Details of the Drug-Related molecule(s) Expression Atlas

General Information of DME (ID: DEON3ED)

• DME Name: Phosphodiesterase 7B (PDE7B) DME Info
• Gene Name: PDE7B

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	1.34E-14	1.23E-01	7.58E-01
Alopecia	ED70	Skin from scalp	1.45E-01	1.13E-01	3.66E-01
Alzheimer's disease	8A20	Entorhinal cortex	5.44E-01	2.26E-02	9.02E-02
Ankylosing spondylitis	FA92.0	Pheripheral blood	9.80E-01	2.53E-02	2.39E-01
Aortic stenosis	BB70	Calcified aortic valve	5.82E-01	-2.19E-01	-3.82E-01
Apnea	7A40	Hyperplastic tonsil	9.22E-01	-8.30E-02	-5.52E-01
Arthropathy	FA00-FA5Z	Peripheral blood	8.56E-01	-1.53E-02	-1.01E-01
Asthma	CA23	Nasal and bronchial airway	3.48E-02	-8.26E-02	-2.05E-01
Atopic dermatitis	EA80	Skin	6.61E-01	-4.67E-02	-3.29E-01
Autism	6A02	Whole blood	8.86E-02	5.48E-02	4.12E-01
Autoimmune uveitis	9A96	Peripheral monocyte	2.68E-02	-2.88E-01	-1.96E+00
Autosomal dominant monocytopenia	4B04	Whole blood	4.09E-01	-7.00E-02	-6.13E-01
Bacterial infection of gingival	1C1H	Gingival tissue	2.36E-15	4.01E-01	1.58E+00
Batten disease	5C56.1	Whole blood	5.65E-01	-1.47E-02	-1.83E-01
Behcet's disease	4A62	Peripheral blood	8.46E-01	2.09E-02	1.35E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	8.25E-01	7.24E-02	1.68E-01
Bladder cancer	2C94	Bladder tissue	4.49E-05	-1.97E+00	-3.94E+00
Breast cancer	2C60-2C6Z	Breast tissue	2.62E-47	-3.05E-01	-1.19E+00
Cardioembolic stroke	8B11.20	Whole blood	7.94E-03	-9.26E-02	-6.00E-01
Cervical cancer	2C77	Cervical tissue	6.20E-01	8.88E-02	3.02E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	4.86E-01	-8.05E-02	-4.94E-01
Chronic hepatitis C	1E51.1	Whole blood	2.88E-01	-3.68E-02	-6.01E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	7.23E-01	5.96E-03	2.67E-02
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	2.78E-01	-2.85E-02	-1.39E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	1.60E-01	-9.63E-02	-1.58E-01
Colon cancer	2B90	Colon tissue	1.83E-70	-4.70E-01	-2.49E+00
Coronary artery disease	BA80-BA8Z	Peripheral blood	2.74E-01	-9.11E-02	-7.97E-01
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	4.63E-01	-1.00E-01	-4.70E-01
Endometriosis	GA10	Endometrium tissue	1.12E-02	-7.22E-02	-1.54E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	6.46E-01	5.79E-02	3.65E-01
Familial hypercholesterolemia	5C80.00	Whole blood	5.57E-01	5.99E-02	4.38E-01
Gastric cancer	2B72	Gastric tissue	4.01E-01	-6.22E-01	-6.32E-01
Glioblastopma	2A00.00	Nervous tissue	1.34E-29	-3.41E-01	-7.71E-01
Glioma	2A00.0Y-2A00.0Z	Brain stem tissue	3.17E-01	-9.84E-03	-1.11E-01
Glioma	2A00.0Y-2A00.0Z	White matter tissue	1.95E-01	-2.70E-01	-4.44E-01
Head and neck cancer	2D42	Head and neck tissue	3.24E-05	-1.09E-01	-4.43E-01
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	1.94E-01	-1.60E-01	-4.17E-01
Huntington's disease	8A01.10	Whole blood	3.16E-01	3.10E-02	1.76E+00
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	2.14E-02	9.46E-02	1.09E+00
Immunodeficiency	4A00-4A20	Peripheral blood	2.54E-01	6.33E-02	4.90E-01
Influenza	1E30	Whole blood	6.90E-01	2.31E-01	1.24E+00
Interstitial cystitis	GC00.3	Bladder tissue	1.03E-02	-1.85E-01	-9.11E-01
Intracranial aneurysm	8B01.0	Intracranial artery	9.37E-01	9.32E-02	3.49E-01
Irritable bowel syndrome	DD91.0	Rectal colon tissue	4.72E-01	4.59E-02	1.08E-01
Ischemic stroke	8B11	Peripheral blood	7.27E-01	4.11E-02	2.18E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	2.39E-01	1.70E-01	3.67E-01
Lateral sclerosis	8B60.4	Skin	2.67E-01	-2.33E-01	-5.56E-01
Lateral sclerosis	8B60.4	Cervical spinal cord	9.63E-01	1.32E-02	7.35E-02
Liver cancer	2C12.0	Liver tissue	7.09E-15	-4.87E-01	-2.01E+00
Liver failure	DB99.7-DB99.8	Liver tissue	6.11E-02	1.89E-01	1.25E+00
Lung cancer	2C25	Lung tissue	2.32E-21	-2.37E-01	-9.45E-01
Lupus erythematosus	4A40	Whole blood	2.46E-02	-1.52E-01	-4.20E-01
Major depressive disorder	6A70-6A7Z	Hippocampus	6.18E-01	-3.99E-02	-8.95E-02
Major depressive disorder	6A70-6A7Z	Whole blood	1.90E-01	-6.00E-02	-2.08E-01
Melanoma	2C30	Skin	1.03E-02	2.92E-01	7.02E-01
Multiple myeloma	2A83.1	Peripheral blood	4.42E-01	9.06E-02	5.37E-01
Multiple myeloma	2A83.1	Bone marrow	2.14E-01	-6.94E-02	-2.91E-01
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	5.47E-01	7.97E-02	2.86E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	6.17E-01	1.13E-02	1.18E-01
Myelofibrosis	2A20.2	Whole blood	8.96E-02	-1.90E-01	-1.66E+00
Myocardial infarction	BA41-BA50	Peripheral blood	9.59E-02	2.19E-01	3.27E-01
Myopathy	8C70.6	Muscle tissue	8.51E-01	-9.23E-03	-4.50E-02
Neonatal sepsis	KA60	Whole blood	9.14E-11	-1.91E-01	-1.04E+00
Neuroectodermal tumour	2A00.11	Brain stem tissue	2.15E-02	-5.56E-01	-1.26E+00
Non-alcoholic fatty liver disease	DB92	Liver tissue	3.02E-01	4.34E-01	8.14E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	3.60E-01	-1.22E-01	-8.12E-01
Olive pollen allergy	CA08.00	Peripheral blood	6.59E-02	9.33E-02	1.30E+00
Oral cancer	2B6E	Oral tissue	3.75E-04	-1.84E-01	-6.90E-01
Osteoarthritis	FA00-FA0Z	Synovial tissue	5.69E-02	-5.93E-02	-5.21E-01
Osteoporosis	FB83.1	Bone marrow	8.06E-01	-7.70E-02	-9.00E-02
Ovarian cancer	2C73	Ovarian tissue	2.82E-03	-1.59E+00	-1.59E+00
Pancreatic cancer	2C10	Pancreas	6.93E-02	-1.86E-01	-6.57E-01
Parkinson's disease	8A00.0	Substantia nigra tissue	3.53E-01	-8.36E-02	-1.75E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	3.17E-04	-1.71E-01	-1.33E+00
Pituitary cancer	2D12	Pituitary tissue	1.60E-03	6.33E-01	1.86E+00
Pituitary gonadotrope tumour	2D12	Pituitary tissue	3.21E-05	1.17E+00	3.65E+00
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	5.97E-01	0.00E+00	0.00E+00
Polycythemia vera	2A20.4	Whole blood	8.40E-01	4.32E-03	2.87E-02
Pompe disease	5C51.3	Biceps muscle	5.72E-03	-5.38E-01	-1.22E+00
Preterm birth	KA21.4Z	Myometrium	7.68E-01	-3.27E-03	-1.41E-02
Prostate cancer	2C82	Prostate	1.93E-01	1.35E-03	4.12E-03
Psoriasis	EA90	Skin	1.28E-05	-1.42E-01	-6.36E-01
Rectal cancer	2B92	Rectal colon tissue	1.25E-03	-2.71E-01	-2.15E+00
Renal cancer	2C90-2C91	Kidney	1.50E-01	-1.67E-01	-3.91E-01
Retinoblastoma	2D02.2	Uvea	3.40E-02	-6.27E-01	-3.27E+00
Rheumatoid arthritis	FA20	Synovial tissue	9.37E-01	-7.30E-02	-7.34E-01
Rhinovirus infection	CA42.1	Nasal epithelium tissue	5.15E-01	-9.11E-02	-2.75E-01
Schizophrenia	6A20	Prefrontal cortex	9.26E-02	-9.23E-02	-1.86E-01
Schizophrenia	6A20	Superior temporal cortex	9.50E-01	-2.53E-02	-1.75E-01
Scleroderma	4A42.Z	Whole blood	3.26E-01	-1.22E-02	-6.99E-02
Seizure	8A60-8A6Z	Whole blood	3.37E-01	8.89E-03	6.38E-02
Sensitive skin	EK0Z	Skin	6.29E-01	-2.16E-03	-1.64E-02
Sepsis with septic shock	1G41	Whole blood	8.60E-14	-1.41E-01	-7.01E-01
Shwachman-Diamond syndrome	3A70.0	Bone marrow	6.82E-01	-1.56E-02	-6.75E-02
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	4.76E-01	5.38E-02	2.44E-01
Simpson golabi behmel syndrome	LD2C	Adipose tissue	8.52E-01	-8.53E-02	-7.46E-01
Sjogren's syndrome	4A43.2	Salivary gland tissue	7.70E-01	-9.62E-02	-4.55E-01
Skin cancer	2C30-2C3Z	Skin	1.93E-03	-2.11E-02	-6.43E-02
Thrombocythemia	3B63	Whole blood	7.86E-01	-6.41E-02	-4.44E-01
Thrombocytopenia	3B64	Whole blood	5.86E-01	-5.76E-02	-2.69E-01
Thyroid cancer	2D10	Thyroid	1.19E-01	-4.43E-02	-1.30E-01
Tibial muscular dystrophy	8C75	Muscle tissue	1.65E-03	5.54E-01	1.87E+00
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	8.78E-02	-5.10E-01	-1.26E+00
Type 2 diabetes	5A11	Liver tissue	9.30E-01	-6.75E-02	-5.91E-01
Ureter cancer	2C92	Urothelium	2.34E-01	-1.01E-01	-4.80E-01
Uterine cancer	2C78	Endometrium tissue	7.34E-02	4.18E-02	1.04E-01
Vitiligo	ED63.0	Skin	1.83E-01	-5.75E-02	-2.58E-01