Details of the Drug-Related molecule(s) Expression Atlas

General Information of DME (ID: DEPLH5Z)

• DME Name: Phosphoenolpyruvate carboxykinase (PCK1) DME Info
• Gene Name: PCK1

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	2.12E-06	-6.52E-02	-4.13E-01
Alopecia	ED70	Skin from scalp	1.62E-02	8.80E-02	7.88E-02
Alzheimer's disease	8A20	Entorhinal cortex	1.42E-03	2.23E-01	3.80E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	2.99E-01	-1.54E-03	-1.72E-02
Aortic stenosis	BB70	Calcified aortic valve	4.04E-02	-4.76E-01	-4.13E-01
Apnea	7A40	Hyperplastic tonsil	5.67E-01	-8.82E-02	-5.90E-01
Arthropathy	FA00-FA5Z	Peripheral blood	7.94E-01	-1.90E-03	-1.47E-02
Asthma	CA23	Nasal and bronchial airway	1.02E-01	-5.33E-02	-2.47E-01
Atopic dermatitis	EA80	Skin	1.07E-01	-1.21E+00	-6.66E-01
Autism	6A02	Whole blood	4.58E-01	-5.42E-02	-3.44E-01
Autoimmune uveitis	9A96	Peripheral monocyte	3.99E-01	2.09E-02	1.06E-01
Autosomal dominant monocytopenia	4B04	Whole blood	6.22E-01	7.34E-03	7.46E-02
Bacterial infection of gingival	1C1H	Gingival tissue	1.52E-01	-4.06E-02	-3.68E-01
Batten disease	5C56.1	Whole blood	6.72E-01	-4.40E-02	-2.21E-01
Behcet's disease	4A62	Peripheral blood	5.92E-01	7.68E-02	4.52E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	4.73E-01	7.36E-02	1.34E-01
Bladder cancer	2C94	Bladder tissue	6.86E-01	1.96E-01	2.76E-01
Breast cancer	2C60-2C6Z	Breast tissue	6.84E-67	-4.11E+00	-1.80E+00
Cardioembolic stroke	8B11.20	Whole blood	5.82E-01	-1.06E-02	-6.47E-02
Cervical cancer	2C77	Cervical tissue	1.43E-02	2.55E-02	1.89E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	4.89E-01	-5.28E-02	-2.69E-01
Chronic hepatitis C	1E51.1	Whole blood	2.93E-01	-8.53E-02	-6.92E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	6.07E-01	-3.73E-03	-1.53E-02
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	3.70E-02	-7.82E-02	-5.67E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	7.46E-01	5.79E-03	3.99E-02
Colon cancer	2B90	Colon tissue	1.30E-126	-3.24E+00	-3.83E+00
Coronary artery disease	BA80-BA8Z	Peripheral blood	8.18E-01	-7.32E-02	-1.38E+00
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	4.71E-01	2.07E-02	9.06E-02
Endometriosis	GA10	Endometrium tissue	5.04E-03	1.35E-01	5.68E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	2.83E-01	-3.66E-02	-2.53E-01
Familial hypercholesterolemia	5C80.00	Whole blood	5.06E-02	-1.44E-01	-7.42E-01
Gastric cancer	2B72	Gastric tissue	1.29E-03	1.85E+00	6.60E+00
Glioblastopma	2A00.00	Nervous tissue	2.57E-11	-1.87E-01	-3.03E-01
Glioma	2A00.0Y-2A00.0Z	Brain stem tissue	1.55E-01	3.28E-01	1.66E+00
Glioma	2A00.0Y-2A00.0Z	White matter tissue	2.07E-01	-2.95E-01	-2.72E-01
Head and neck cancer	2D42	Head and neck tissue	1.40E-01	-9.10E-02	-2.10E-01
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	1.39E-02	1.36E-01	5.61E-01
Huntington's disease	8A01.10	Whole blood	5.19E-01	4.20E-02	3.93E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	2.89E-01	-1.05E-01	-4.78E-01
Immunodeficiency	4A00-4A20	Peripheral blood	3.95E-01	5.36E-02	5.28E-01
Influenza	1E30	Whole blood	1.56E-02	3.20E-01	2.88E+00
Interstitial cystitis	GC00.3	Bladder tissue	4.01E-01	1.03E-02	2.37E-02
Intracranial aneurysm	8B01.0	Intracranial artery	2.81E-03	-1.03E+00	-7.08E-01
Irritable bowel syndrome	DD91.0	Rectal colon tissue	2.96E-01	4.55E-02	9.64E-02
Ischemic stroke	8B11	Peripheral blood	1.67E-01	1.13E-01	5.49E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	5.56E-01	3.65E-02	1.34E-01
Lateral sclerosis	8B60.4	Skin	6.62E-01	3.03E-02	1.69E-01
Lateral sclerosis	8B60.4	Cervical spinal cord	8.39E-01	6.87E-02	1.87E-01
Liver cancer	2C12.0	Liver tissue	3.30E-14	-1.82E+00	-1.55E+00
Liver failure	DB99.7-DB99.8	Liver tissue	9.36E-02	-2.71E+00	-3.28E+00
Lung cancer	2C25	Lung tissue	3.86E-15	1.42E-01	2.71E-01
Lupus erythematosus	4A40	Whole blood	9.64E-01	-1.27E-02	-4.74E-02
Major depressive disorder	6A70-6A7Z	Hippocampus	8.91E-01	6.13E-02	1.38E-01
Major depressive disorder	6A70-6A7Z	Whole blood	2.19E-01	-7.75E-03	-3.45E-02
Melanoma	2C30	Skin	1.65E-03	-2.26E+00	-1.25E+00
Multiple myeloma	2A83.1	Peripheral blood	6.65E-02	5.12E-02	5.26E-01
Multiple myeloma	2A83.1	Bone marrow	7.59E-01	-5.48E-02	-8.82E-01
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	2.24E-01	-3.31E-02	-7.02E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	4.27E-02	6.63E-02	5.11E-01
Myelofibrosis	2A20.2	Whole blood	7.36E-01	1.68E-02	1.80E-01
Myocardial infarction	BA41-BA50	Peripheral blood	8.02E-02	-7.61E-02	-1.21E-01
Myopathy	8C70.6	Muscle tissue	2.20E-02	2.42E-01	8.73E-01
Neonatal sepsis	KA60	Whole blood	2.28E-01	2.91E-02	2.06E-01
Neuroectodermal tumour	2A00.11	Brain stem tissue	3.14E-04	4.98E-02	2.30E-01
Non-alcoholic fatty liver disease	DB92	Liver tissue	5.48E-01	-1.28E-01	-3.68E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	6.11E-02	1.37E+00	1.71E+00
Olive pollen allergy	CA08.00	Peripheral blood	5.67E-01	8.34E-03	7.33E-02
Oral cancer	2B6E	Oral tissue	2.16E-03	-3.90E-01	-5.41E-01
Osteoarthritis	FA00-FA0Z	Synovial tissue	3.18E-01	-2.82E+00	-1.15E+00
Osteoporosis	FB83.1	Bone marrow	6.98E-01	-4.11E-02	-5.53E-01
Ovarian cancer	2C73	Ovarian tissue	2.37E-02	5.72E-01	5.51E-01
Pancreatic cancer	2C10	Pancreas	3.57E-01	-8.07E-01	-3.77E-01
Parkinson's disease	8A00.0	Substantia nigra tissue	1.17E-01	3.22E-01	6.72E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	6.07E-01	-2.95E-02	-1.64E-01
Pituitary cancer	2D12	Pituitary tissue	5.67E-10	-6.44E+00	-6.70E+00
Pituitary gonadotrope tumour	2D12	Pituitary tissue	8.79E-09	-6.65E+00	-7.48E+00
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	7.37E-01	1.00E-01	2.23E-01
Polycythemia vera	2A20.4	Whole blood	1.28E-03	3.61E-02	3.59E-01
Pompe disease	5C51.3	Biceps muscle	5.75E-02	-1.55E-01	-6.82E-01
Preterm birth	KA21.4Z	Myometrium	3.26E-01	4.25E-02	1.96E-01
Prostate cancer	2C82	Prostate	1.82E-01	-2.43E-01	-1.35E-01
Psoriasis	EA90	Skin	1.63E-08	-1.25E+00	-9.77E-01
Rectal cancer	2B92	Rectal colon tissue	1.15E-14	-2.78E+00	-7.69E+00
Renal cancer	2C90-2C91	Kidney	3.89E-04	-4.64E+00	-2.03E+00
Retinoblastoma	2D02.2	Uvea	4.24E-03	-3.98E-01	-5.73E-01
Rheumatoid arthritis	FA20	Synovial tissue	3.31E-05	-4.24E+00	-4.52E+00
Rhinovirus infection	CA42.1	Nasal epithelium tissue	1.19E-01	6.88E-02	6.54E-01
Schizophrenia	6A20	Prefrontal cortex	3.77E-01	-5.56E-04	-1.23E-03
Schizophrenia	6A20	Superior temporal cortex	7.29E-01	-8.89E-03	-5.37E-02
Scleroderma	4A42.Z	Whole blood	1.71E-04	3.00E-01	2.02E+00
Seizure	8A60-8A6Z	Whole blood	1.10E-01	-1.56E-01	-8.60E-01
Sensitive skin	EK0Z	Skin	9.53E-01	-2.80E-01	-3.22E-01
Sepsis with septic shock	1G41	Whole blood	4.26E-02	4.84E-02	3.12E-01
Shwachman-Diamond syndrome	3A70.0	Bone marrow	1.34E-01	2.03E-01	1.05E+00
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	2.72E-01	5.90E-02	7.46E-01
Simpson golabi behmel syndrome	LD2C	Adipose tissue	9.95E-01	-2.49E-01	-2.18E-01
Sjogren's syndrome	4A43.2	Salivary gland tissue	7.95E-01	-8.14E-02	-2.07E-01
Skin cancer	2C30-2C3Z	Skin	6.80E-43	-2.00E+00	-1.31E+00
Thrombocythemia	3B63	Whole blood	1.48E-01	-6.62E-04	-6.55E-03
Thrombocytopenia	3B64	Whole blood	3.66E-01	3.49E+00	1.51E+00
Thyroid cancer	2D10	Thyroid	3.84E-02	-1.65E-01	-3.82E-01
Tibial muscular dystrophy	8C75	Muscle tissue	1.41E-01	4.22E-01	5.44E-01
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	6.76E-01	-6.58E-02	-1.42E+00
Type 2 diabetes	5A11	Liver tissue	6.20E-01	3.22E-01	4.07E-01
Ureter cancer	2C92	Urothelium	3.70E-01	-2.48E-02	-7.70E-02
Uterine cancer	2C78	Endometrium tissue	1.82E-14	2.78E-01	5.01E-01
Vitiligo	ED63.0	Skin	7.58E-01	-2.70E-01	-1.28E-01