Details of the Drug-Related molecule(s) Expression Atlas

General Information of DME (ID: DEPTJ3D)

• DME Name: Steroid 5-alpha-reductase 2 (SRD5A2) DME Info
• Gene Name: SRD5A2

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	6.52E-02	1.61E-02	9.76E-02
Alopecia	ED70	Skin from scalp	3.65E-01	-1.53E-01	-3.53E-01
Alzheimer's disease	8A20	Entorhinal cortex	9.64E-01	7.96E-03	4.87E-02
Ankylosing spondylitis	FA92.0	Pheripheral blood	9.57E-01	1.27E-03	1.11E-02
Aortic stenosis	BB70	Calcified aortic valve	9.54E-01	1.40E-01	3.52E-01
Apnea	7A40	Hyperplastic tonsil	1.30E-01	-2.64E-01	-2.44E+00
Arthropathy	FA00-FA5Z	Peripheral blood	2.58E-02	1.20E-01	9.35E-01
Asthma	CA23	Nasal and bronchial airway	6.90E-01	6.11E-02	6.28E-02
Atopic dermatitis	EA80	Skin	7.85E-01	-4.88E-02	-4.79E-01
Autism	6A02	Whole blood	8.21E-01	1.86E-02	8.93E-02
Autoimmune uveitis	9A96	Peripheral monocyte	5.57E-01	-1.76E-01	-1.81E+00
Autosomal dominant monocytopenia	4B04	Whole blood	2.52E-02	-2.20E-01	-1.45E+00
Bacterial infection of gingival	1C1H	Gingival tissue	1.53E-05	1.06E-01	5.44E-01
Batten disease	5C56.1	Whole blood	8.96E-01	-6.32E-04	-6.95E-03
Behcet's disease	4A62	Peripheral blood	3.50E-01	-5.14E-02	-1.51E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	7.88E-01	-1.27E-02	-7.92E-02
Bladder cancer	2C94	Bladder tissue	3.02E-03	-3.49E-01	-1.89E+00
Breast cancer	2C60-2C6Z	Breast tissue	4.51E-05	8.69E-02	3.21E-01
Cardioembolic stroke	8B11.20	Whole blood	1.55E-01	8.03E-02	4.37E-01
Cervical cancer	2C77	Cervical tissue	5.21E-01	-4.17E-03	-1.59E-02
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	6.21E-01	-1.97E-02	-1.07E-01
Chronic hepatitis C	1E51.1	Whole blood	2.73E-01	1.34E-02	8.80E-02
Chronic obstructive pulmonary disease	CA22	Lung tissue	5.41E-01	4.88E-02	2.04E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	8.35E-08	3.33E-01	6.13E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	1.49E-01	-7.75E-01	-8.92E-01
Colon cancer	2B90	Colon tissue	2.70E-10	-1.73E-01	-6.97E-01
Coronary artery disease	BA80-BA8Z	Peripheral blood	3.44E-01	-4.43E-01	-6.99E-01
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	9.54E-01	-3.72E-02	-3.63E-01
Endometriosis	GA10	Endometrium tissue	5.61E-01	4.78E-02	1.63E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	3.30E-02	1.45E-01	1.00E+00
Familial hypercholesterolemia	5C80.00	Whole blood	1.19E-02	-1.04E-01	-4.40E-01
Gastric cancer	2B72	Gastric tissue	1.23E-01	-6.97E-01	-2.09E+00
Glioblastopma	2A00.00	Nervous tissue	1.60E-52	-3.14E-01	-1.18E+00
Glioma	2A00.0Y-2A00.0Z	Brain stem tissue	4.43E-01	-1.67E-01	-9.44E-01
Glioma	2A00.0Y-2A00.0Z	White matter tissue	1.16E-01	5.09E-02	1.73E-01
Head and neck cancer	2D42	Head and neck tissue	3.55E-14	-4.97E-01	-2.98E-01
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	1.64E-01	-1.16E-01	-4.14E-01
Huntington's disease	8A01.10	Whole blood	5.75E-01	1.62E-02	5.90E-02
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	8.56E-01	7.76E-03	2.59E-02
Immunodeficiency	4A00-4A20	Peripheral blood	2.25E-01	8.27E-02	1.39E+00
Influenza	1E30	Whole blood	9.18E-03	5.28E-01	3.07E+00
Interstitial cystitis	GC00.3	Bladder tissue	2.01E-01	-1.60E-01	-3.57E-01
Intracranial aneurysm	8B01.0	Intracranial artery	8.29E-01	7.49E-03	2.25E-02
Irritable bowel syndrome	DD91.0	Rectal colon tissue	2.39E-01	7.11E-02	3.40E-01
Ischemic stroke	8B11	Peripheral blood	5.52E-02	6.05E-02	5.63E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	1.11E-03	1.47E-01	5.77E-01
Lateral sclerosis	8B60.4	Skin	2.02E-01	1.52E-01	9.19E-01
Lateral sclerosis	8B60.4	Cervical spinal cord	5.20E-01	6.28E-02	3.39E-01
Liver cancer	2C12.0	Liver tissue	1.81E-24	-3.11E+00	-3.33E+00
Liver failure	DB99.7-DB99.8	Liver tissue	8.82E-06	-1.91E+00	-2.62E+00
Lung cancer	2C25	Lung tissue	5.50E-06	-2.04E-01	-3.32E-01
Lupus erythematosus	4A40	Whole blood	9.02E-01	-3.98E-02	-9.83E-02
Major depressive disorder	6A70-6A7Z	Hippocampus	4.02E-01	-6.86E-02	-5.30E-01
Major depressive disorder	6A70-6A7Z	Whole blood	1.01E-02	4.10E-02	2.54E-01
Melanoma	2C30	Skin	4.10E-03	-3.26E-01	-4.42E-01
Multiple myeloma	2A83.1	Peripheral blood	3.64E-01	-5.25E-02	-2.51E-01
Multiple myeloma	2A83.1	Bone marrow	2.30E-01	-4.32E-02	-4.08E-01
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	4.85E-01	-5.25E-02	-3.48E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	5.85E-01	4.02E-03	2.47E-02
Myelofibrosis	2A20.2	Whole blood	4.58E-02	7.70E-02	4.86E-01
Myocardial infarction	BA41-BA50	Peripheral blood	6.55E-01	4.81E-02	1.21E-01
Myopathy	8C70.6	Muscle tissue	1.11E-02	-2.72E-01	-1.46E+00
Neonatal sepsis	KA60	Whole blood	5.11E-03	3.46E-02	1.69E-01
Neuroectodermal tumour	2A00.11	Brain stem tissue	2.82E-04	-5.31E-01	-1.96E+00
Non-alcoholic fatty liver disease	DB92	Liver tissue	4.90E-03	9.68E-01	1.39E+00
Obesity related type 2 diabetes	5A11	Omental adipose tissue	9.11E-01	-2.74E-03	-3.19E-02
Olive pollen allergy	CA08.00	Peripheral blood	6.82E-01	7.06E-02	3.22E-01
Oral cancer	2B6E	Oral tissue	4.22E-06	-3.03E-01	-1.21E+00
Osteoarthritis	FA00-FA0Z	Synovial tissue	1.59E-01	-2.76E-01	-8.20E-01
Osteoporosis	FB83.1	Bone marrow	3.61E-02	3.17E-01	1.46E+00
Ovarian cancer	2C73	Ovarian tissue	7.16E-01	6.92E-02	6.13E-02
Pancreatic cancer	2C10	Pancreas	4.06E-01	-1.22E-01	-3.55E-01
Parkinson's disease	8A00.0	Substantia nigra tissue	5.29E-01	5.82E-02	2.01E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	6.24E-01	4.15E-03	2.75E-02
Pituitary cancer	2D12	Pituitary tissue	2.03E-04	2.55E-01	1.57E+00
Pituitary gonadotrope tumour	2D12	Pituitary tissue	2.65E-02	2.64E-01	1.44E+00
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	2.58E-01	-6.45E-02	-5.50E-01
Polycythemia vera	2A20.4	Whole blood	6.17E-09	2.03E-01	1.29E+00
Pompe disease	5C51.3	Biceps muscle	1.25E-01	-1.75E-01	-8.41E-01
Preterm birth	KA21.4Z	Myometrium	5.83E-01	-7.76E-03	-3.95E-02
Prostate cancer	2C82	Prostate	1.43E-01	4.83E-01	5.62E-01
Psoriasis	EA90	Skin	3.90E-05	-1.15E-01	-4.10E-01
Rectal cancer	2B92	Rectal colon tissue	2.06E-01	-1.23E-01	-5.52E-01
Renal cancer	2C90-2C91	Kidney	4.20E-03	-3.79E-01	-1.10E+00
Retinoblastoma	2D02.2	Uvea	3.34E-03	-1.51E-01	-1.38E+00
Rheumatoid arthritis	FA20	Synovial tissue	1.91E-03	-6.27E-01	-2.00E+00
Rhinovirus infection	CA42.1	Nasal epithelium tissue	6.76E-01	-5.33E-02	-7.23E-02
Schizophrenia	6A20	Prefrontal cortex	3.63E-01	-3.25E-02	-1.22E-01
Schizophrenia	6A20	Superior temporal cortex	4.36E-01	-2.96E-02	-3.00E-01
Scleroderma	4A42.Z	Whole blood	1.81E-01	1.04E-01	8.16E-01
Seizure	8A60-8A6Z	Whole blood	6.64E-02	-2.07E-01	-9.60E-01
Sensitive skin	EK0Z	Skin	8.24E-01	-7.25E-02	-3.31E-01
Sepsis with septic shock	1G41	Whole blood	8.76E-01	1.51E-03	5.86E-03
Shwachman-Diamond syndrome	3A70.0	Bone marrow	3.61E-01	-1.56E-01	-9.61E-01
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	1.59E-01	2.18E-01	5.46E-01
Simpson golabi behmel syndrome	LD2C	Adipose tissue	1.21E-01	1.10E-01	8.25E-01
Sjogren's syndrome	4A43.2	Salivary gland tissue	3.63E-01	8.61E-02	1.02E+00
Skin cancer	2C30-2C3Z	Skin	7.51E-02	-1.23E-01	-2.96E-01
Thrombocythemia	3B63	Whole blood	6.93E-04	6.51E-02	4.14E-01
Thrombocytopenia	3B64	Whole blood	6.09E-01	0.00E+00	0.00E+00
Thyroid cancer	2D10	Thyroid	2.77E-03	6.21E-02	3.37E-01
Tibial muscular dystrophy	8C75	Muscle tissue	1.09E-05	-3.17E-01	-1.65E+00
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	5.05E-01	-1.10E-02	-1.43E-01
Type 2 diabetes	5A11	Liver tissue	3.81E-01	-2.08E-01	-5.17E-01
Ureter cancer	2C92	Urothelium	7.15E-01	3.75E-02	1.11E-01
Uterine cancer	2C78	Endometrium tissue	3.87E-02	3.95E-02	1.04E-01
Vitiligo	ED63.0	Skin	3.60E-01	-8.92E-02	-2.49E-01