Details of the Drug-Related molecule(s) Expression Atlas

General Information of DME (ID: DEPTKBQ)

• DME Name: Tryptophanyl-tRNA synthetase mitochondrial (WARS2) DME Info
• Gene Name: WARS2

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	2.31E-06	2.03E-01	5.60E-01
Alopecia	ED70	Skin from scalp	6.10E-01	9.40E-02	2.72E-01
Alzheimer's disease	8A20	Entorhinal cortex	1.65E-01	-4.34E-02	-1.55E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	2.38E-01	2.51E-01	7.17E-01
Aortic stenosis	BB70	Calcified aortic valve	9.17E-01	1.68E-01	1.83E-01
Apnea	7A40	Hyperplastic tonsil	5.08E-01	-2.45E-01	-1.08E+00
Arthropathy	FA00-FA5Z	Peripheral blood	7.35E-02	-1.71E-01	-6.19E-01
Asthma	CA23	Nasal and bronchial airway	1.01E-06	4.74E-01	6.84E-01
Atopic dermatitis	EA80	Skin	1.66E-01	-1.23E-01	-6.05E-01
Autism	6A02	Whole blood	2.27E-01	2.08E-02	1.07E-01
Autoimmune uveitis	9A96	Peripheral monocyte	6.66E-01	-2.35E-01	-5.62E-01
Autosomal dominant monocytopenia	4B04	Whole blood	4.15E-01	-6.72E-02	-2.71E-01
Bacterial infection of gingival	1C1H	Gingival tissue	8.47E-06	-2.12E-01	-5.20E-01
Batten disease	5C56.1	Whole blood	4.40E-01	-2.12E-01	-9.27E-01
Behcet's disease	4A62	Peripheral blood	9.36E-01	5.47E-02	1.54E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	5.53E-01	9.40E-02	3.04E-01
Bladder cancer	2C94	Bladder tissue	3.69E-06	-1.11E+00	-3.89E+00
Breast cancer	2C60-2C6Z	Breast tissue	4.06E-09	1.54E-01	2.67E-01
Cardioembolic stroke	8B11.20	Whole blood	1.03E-01	3.32E-01	3.59E-01
Cervical cancer	2C77	Cervical tissue	6.09E-01	1.32E-02	2.94E-02
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	8.51E-01	-2.72E-01	-3.20E-01
Chronic hepatitis C	1E51.1	Whole blood	5.84E-01	2.10E-01	3.13E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	3.77E-01	-1.06E-01	-2.56E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	1.65E-01	-1.36E-01	-3.22E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	1.12E-01	-1.50E-01	-5.23E-01
Colon cancer	2B90	Colon tissue	4.68E-03	5.86E-02	1.14E-01
Coronary artery disease	BA80-BA8Z	Peripheral blood	7.25E-01	-1.03E-01	-6.57E-01
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	8.56E-01	5.53E-05	1.35E-04
Endometriosis	GA10	Endometrium tissue	1.93E-02	-5.77E-01	-7.25E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	7.92E-01	6.18E-02	2.45E-01
Familial hypercholesterolemia	5C80.00	Whole blood	1.57E-04	6.54E-01	1.76E+00
Gastric cancer	2B72	Gastric tissue	1.48E-01	1.08E+00	1.26E+00
Glioblastopma	2A00.00	Nervous tissue	4.20E-51	4.42E-01	1.05E+00
Glioma	2A00.0Y-2A00.0Z	Brain stem tissue	1.34E-04	3.30E-01	2.86E+01
Glioma	2A00.0Y-2A00.0Z	White matter tissue	8.56E-02	5.47E-01	8.53E-01
Head and neck cancer	2D42	Head and neck tissue	2.25E-01	-7.58E-02	-1.72E-01
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	4.72E-01	-1.12E-01	-4.19E-01
Huntington's disease	8A01.10	Whole blood	1.18E-01	-1.66E-01	-1.05E+00
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	7.14E-01	-8.94E-03	-3.32E-02
Immunodeficiency	4A00-4A20	Peripheral blood	1.10E-01	7.14E-02	3.14E-01
Influenza	1E30	Whole blood	3.14E-04	-1.69E+00	-5.58E+01
Interstitial cystitis	GC00.3	Bladder tissue	5.05E-03	-7.40E-01	-2.32E+00
Intracranial aneurysm	8B01.0	Intracranial artery	1.06E-01	-1.94E-01	-1.54E+00
Irritable bowel syndrome	DD91.0	Rectal colon tissue	6.54E-01	-6.33E-02	-1.29E-01
Ischemic stroke	8B11	Peripheral blood	7.07E-01	-6.75E-02	-2.07E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	7.05E-01	-5.84E-02	-9.58E-02
Lateral sclerosis	8B60.4	Skin	4.15E-01	1.33E-01	1.18E+00
Lateral sclerosis	8B60.4	Cervical spinal cord	2.54E-01	-1.04E-01	-3.44E-01
Liver cancer	2C12.0	Liver tissue	3.99E-08	3.02E-01	8.09E-01
Liver failure	DB99.7-DB99.8	Liver tissue	7.07E-02	4.39E-01	1.61E+00
Lung cancer	2C25	Lung tissue	6.86E-04	2.35E-02	5.97E-02
Lupus erythematosus	4A40	Whole blood	6.23E-01	7.31E-02	1.25E-01
Major depressive disorder	6A70-6A7Z	Hippocampus	6.26E-01	-6.74E-03	-2.15E-02
Major depressive disorder	6A70-6A7Z	Whole blood	8.48E-01	-4.35E-02	-7.39E-02
Melanoma	2C30	Skin	8.24E-01	-5.41E-02	-7.10E-02
Multiple myeloma	2A83.1	Peripheral blood	3.42E-01	-7.10E-01	-1.02E+00
Multiple myeloma	2A83.1	Bone marrow	1.32E-06	6.43E-01	3.73E+00
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	9.93E-01	-1.02E-01	-1.62E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	8.27E-01	-4.28E-02	-9.08E-02
Myelofibrosis	2A20.2	Whole blood	2.57E-01	-1.34E-01	-5.28E-01
Myocardial infarction	BA41-BA50	Peripheral blood	4.81E-02	-4.20E-01	-5.08E-01
Myopathy	8C70.6	Muscle tissue	2.37E-01	-2.39E-03	-5.85E-03
Neonatal sepsis	KA60	Whole blood	4.90E-11	-3.71E-01	-1.40E+00
Neuroectodermal tumour	2A00.11	Brain stem tissue	9.47E-07	1.53E+00	3.28E+00
Non-alcoholic fatty liver disease	DB92	Liver tissue	1.09E-01	1.73E-01	8.33E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	5.33E-02	-6.70E-01	-1.07E+00
Olive pollen allergy	CA08.00	Peripheral blood	2.94E-01	-2.37E-01	-2.83E-01
Oral cancer	2B6E	Oral tissue	3.51E-06	6.52E-01	1.46E+00
Osteoarthritis	FA00-FA0Z	Synovial tissue	7.41E-01	-8.18E-02	-2.11E-01
Osteoporosis	FB83.1	Bone marrow	2.80E-01	-2.52E-01	-7.85E-01
Ovarian cancer	2C73	Ovarian tissue	2.45E-02	4.08E-01	7.36E-01
Pancreatic cancer	2C10	Pancreas	2.91E-01	-1.89E-01	-3.46E-01
Parkinson's disease	8A00.0	Substantia nigra tissue	2.74E-01	-1.70E-01	-7.10E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	2.96E-01	-6.73E-02	-1.56E-01
Pituitary cancer	2D12	Pituitary tissue	1.97E-01	-5.68E-01	-1.05E+00
Pituitary gonadotrope tumour	2D12	Pituitary tissue	2.34E-01	-4.83E-01	-1.19E+00
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	9.21E-01	5.53E-03	3.32E-02
Polycythemia vera	2A20.4	Whole blood	2.82E-09	-3.59E-01	-1.27E+00
Pompe disease	5C51.3	Biceps muscle	7.65E-01	-1.88E-02	-5.46E-02
Preterm birth	KA21.4Z	Myometrium	4.64E-01	3.29E-02	5.17E-02
Prostate cancer	2C82	Prostate	4.97E-02	2.13E-01	2.05E-01
Psoriasis	EA90	Skin	5.07E-01	6.51E-02	1.30E-01
Rectal cancer	2B92	Rectal colon tissue	6.28E-01	1.50E-01	5.18E-01
Renal cancer	2C90-2C91	Kidney	3.70E-02	6.55E-01	1.07E+00
Retinoblastoma	2D02.2	Uvea	6.22E-03	6.47E-01	2.46E+00
Rheumatoid arthritis	FA20	Synovial tissue	5.08E-02	2.32E-01	3.28E-01
Rhinovirus infection	CA42.1	Nasal epithelium tissue	3.46E-01	7.90E-03	3.27E-02
Schizophrenia	6A20	Prefrontal cortex	6.89E-01	-1.44E-02	-2.47E-02
Schizophrenia	6A20	Superior temporal cortex	6.15E-01	3.29E-02	2.06E-01
Scleroderma	4A42.Z	Whole blood	1.65E-03	2.85E-01	1.66E+00
Seizure	8A60-8A6Z	Whole blood	8.12E-01	1.36E-01	4.97E-01
Sensitive skin	EK0Z	Skin	2.12E-01	-6.74E-02	-2.70E-01
Sepsis with septic shock	1G41	Whole blood	3.93E-23	-2.94E-01	-1.15E+00
Shwachman-Diamond syndrome	3A70.0	Bone marrow	4.36E-01	-5.40E-01	-9.11E-01
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	4.15E-03	-1.25E-01	-1.48E+00
Simpson golabi behmel syndrome	LD2C	Adipose tissue	9.22E-01	-2.98E-02	-1.25E-01
Sjogren's syndrome	4A43.2	Salivary gland tissue	4.74E-01	-8.95E-02	-2.06E-01
Skin cancer	2C30-2C3Z	Skin	9.76E-04	-1.97E-01	-4.13E-01
Thrombocythemia	3B63	Whole blood	2.60E-05	-4.20E-01	-1.61E+00
Thrombocytopenia	3B64	Whole blood	7.28E-01	1.65E-01	2.33E-01
Thyroid cancer	2D10	Thyroid	2.03E-01	-9.33E-02	-2.55E-01
Tibial muscular dystrophy	8C75	Muscle tissue	9.43E-01	1.00E-01	3.59E-01
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	2.78E-01	-9.21E-02	-3.41E-01
Type 2 diabetes	5A11	Liver tissue	2.61E-01	5.44E-01	1.05E+00
Ureter cancer	2C92	Urothelium	5.74E-01	5.55E-02	3.37E-01
Uterine cancer	2C78	Endometrium tissue	9.92E-01	-5.74E-02	-1.05E-01
Vitiligo	ED63.0	Skin	2.10E-03	-2.07E-01	-1.73E+00