Details of the Drug-Related molecule(s) Expression Atlas

General Information of DME (ID: DER5U19)

• DME Name: Bifunctional epoxide hydrolase 2 (EPHX2) DME Info
• Gene Name: EPHX2

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	8.13E-21	-4.03E-01	-1.19E+00
Alopecia	ED70	Skin from scalp	9.38E-01	-2.14E-02	-8.33E-02
Alzheimer's disease	8A20	Entorhinal cortex	2.80E-01	1.52E-01	3.52E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	1.54E-01	-7.67E-02	-5.67E-01
Aortic stenosis	BB70	Calcified aortic valve	2.50E-01	-7.67E-01	-7.31E-01
Apnea	7A40	Hyperplastic tonsil	7.75E-01	8.05E-03	9.74E-03
Arthropathy	FA00-FA5Z	Peripheral blood	7.33E-02	-5.09E-01	-1.18E+00
Asthma	CA23	Nasal and bronchial airway	2.83E-03	1.74E-01	2.09E-01
Atopic dermatitis	EA80	Skin	6.41E-10	-5.33E-01	-2.44E+00
Autism	6A02	Whole blood	5.14E-01	-3.53E-02	-1.11E-01
Autoimmune uveitis	9A96	Peripheral monocyte	4.09E-01	-8.99E-02	-5.88E-01
Autosomal dominant monocytopenia	4B04	Whole blood	8.37E-02	-1.46E-01	-5.80E-01
Bacterial infection of gingival	1C1H	Gingival tissue	9.50E-10	-4.88E-01	-9.48E-01
Batten disease	5C56.1	Whole blood	2.12E-01	-4.91E-01	-2.14E+00
Behcet's disease	4A62	Peripheral blood	6.05E-01	2.39E-01	5.60E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	1.34E-01	-2.29E-02	-1.05E-01
Bladder cancer	2C94	Bladder tissue	9.04E-07	-2.28E+00	-5.77E+00
Breast cancer	2C60-2C6Z	Breast tissue	4.64E-65	-8.86E-01	-1.64E+00
Cardioembolic stroke	8B11.20	Whole blood	7.19E-09	-7.87E-01	-1.57E+00
Cervical cancer	2C77	Cervical tissue	1.84E-06	-1.02E+00	-1.69E+00
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	5.31E-01	6.37E-02	6.38E-02
Chronic hepatitis C	1E51.1	Whole blood	5.21E-01	-1.38E-01	-2.67E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	8.78E-01	-1.03E-01	-2.69E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	4.40E-02	-1.81E-01	-4.23E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	5.35E-03	-4.73E-01	-1.06E+00
Colon cancer	2B90	Colon tissue	1.08E-126	-1.82E+00	-3.99E+00
Coronary artery disease	BA80-BA8Z	Peripheral blood	5.30E-01	-6.87E-02	-3.27E-01
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	1.07E-01	1.04E-01	4.93E-01
Endometriosis	GA10	Endometrium tissue	2.78E-01	-5.91E-01	-7.31E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	9.02E-01	-9.03E-02	-1.80E-01
Familial hypercholesterolemia	5C80.00	Whole blood	2.34E-11	-9.43E-01	-1.47E+00
Gastric cancer	2B72	Gastric tissue	9.77E-01	1.86E-01	6.19E-01
Glioblastopma	2A00.00	Nervous tissue	2.24E-07	8.44E-02	1.66E-01
Glioma	2A00.0Y-2A00.0Z	Brain stem tissue	7.02E-01	-8.50E-02	-7.12E-01
Glioma	2A00.0Y-2A00.0Z	White matter tissue	1.01E-02	-7.81E-01	-1.33E+00
Head and neck cancer	2D42	Head and neck tissue	1.12E-63	-2.05E+00	-4.09E+00
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	4.58E-01	2.44E-02	7.49E-02
Huntington's disease	8A01.10	Whole blood	2.18E-01	2.32E-01	4.95E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	1.47E-02	8.02E-01	1.71E+00
Immunodeficiency	4A00-4A20	Peripheral blood	1.28E-02	-4.34E-01	-1.30E+00
Influenza	1E30	Whole blood	3.58E-01	-6.95E-03	-1.62E-01
Interstitial cystitis	GC00.3	Bladder tissue	1.35E-04	-1.07E+00	-5.19E+00
Intracranial aneurysm	8B01.0	Intracranial artery	5.95E-06	-1.10E+00	-3.84E+00
Irritable bowel syndrome	DD91.0	Rectal colon tissue	1.44E-02	-1.65E-01	-3.96E-01
Ischemic stroke	8B11	Peripheral blood	8.58E-01	4.47E-02	8.16E-02
Juvenile idiopathic arthritis	FA24	Peripheral blood	6.35E-10	-4.93E-01	-1.03E+00
Lateral sclerosis	8B60.4	Skin	4.31E-01	-1.33E-01	-3.26E-01
Lateral sclerosis	8B60.4	Cervical spinal cord	1.12E-01	-1.80E-01	-5.73E-01
Liver cancer	2C12.0	Liver tissue	3.30E-19	-1.90E+00	-2.39E+00
Liver failure	DB99.7-DB99.8	Liver tissue	1.01E-03	-2.61E+00	-6.39E+00
Lung cancer	2C25	Lung tissue	1.74E-30	-7.39E-01	-1.48E+00
Lupus erythematosus	4A40	Whole blood	1.83E-04	-3.07E-01	-4.27E-01
Major depressive disorder	6A70-6A7Z	Hippocampus	8.35E-01	-1.10E-02	-4.82E-02
Major depressive disorder	6A70-6A7Z	Whole blood	3.43E-01	-1.34E-01	-2.45E-01
Melanoma	2C30	Skin	6.35E-04	-1.72E+00	-1.34E+00
Multiple myeloma	2A83.1	Peripheral blood	4.66E-01	5.04E-02	2.96E-01
Multiple myeloma	2A83.1	Bone marrow	9.01E-06	7.51E-01	2.72E+00
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	1.16E-01	2.96E-01	1.46E+00
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	1.36E-01	2.67E-01	5.96E-01
Myelofibrosis	2A20.2	Whole blood	1.21E-03	-4.72E-01	-2.36E+00
Myocardial infarction	BA41-BA50	Peripheral blood	1.36E-01	-2.61E-01	-2.99E-01
Myopathy	8C70.6	Muscle tissue	9.53E-01	1.01E-02	4.81E-02
Neonatal sepsis	KA60	Whole blood	2.74E-33	-1.13E+00	-2.16E+00
Neuroectodermal tumour	2A00.11	Brain stem tissue	4.92E-01	-2.83E-02	-7.73E-02
Non-alcoholic fatty liver disease	DB92	Liver tissue	5.39E-01	-6.56E-03	-1.11E-02
Obesity related type 2 diabetes	5A11	Omental adipose tissue	5.30E-01	-1.27E-01	-8.70E-01
Olive pollen allergy	CA08.00	Peripheral blood	7.63E-01	3.21E-02	1.14E-01
Oral cancer	2B6E	Oral tissue	3.49E-11	-1.54E+00	-2.38E+00
Osteoarthritis	FA00-FA0Z	Synovial tissue	9.43E-01	-2.89E-01	-4.17E-01
Osteoporosis	FB83.1	Bone marrow	5.03E-02	3.61E-01	1.03E+00
Ovarian cancer	2C73	Ovarian tissue	4.38E-02	-8.19E-01	-1.04E+00
Pancreatic cancer	2C10	Pancreas	8.87E-04	-1.18E+00	-1.49E+00
Parkinson's disease	8A00.0	Substantia nigra tissue	2.21E-01	-2.36E-01	-5.15E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	1.41E-02	-5.06E-01	-1.14E+00
Pituitary cancer	2D12	Pituitary tissue	4.80E-01	4.20E-01	8.05E-01
Pituitary gonadotrope tumour	2D12	Pituitary tissue	1.33E-02	4.87E-01	9.94E-01
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	9.07E-01	1.25E-02	5.10E-02
Polycythemia vera	2A20.4	Whole blood	5.79E-15	-3.98E-01	-2.28E+00
Pompe disease	5C51.3	Biceps muscle	2.24E-01	-4.11E-01	-7.41E-01
Preterm birth	KA21.4Z	Myometrium	5.01E-02	4.76E-01	1.51E+00
Prostate cancer	2C82	Prostate	2.76E-01	-2.08E-01	-1.95E-01
Psoriasis	EA90	Skin	3.38E-04	-3.39E-01	-6.29E-01
Rectal cancer	2B92	Rectal colon tissue	6.21E-15	-1.71E+00	-9.42E+00
Renal cancer	2C90-2C91	Kidney	3.58E-05	-1.34E+00	-1.87E+00
Retinoblastoma	2D02.2	Uvea	9.29E-01	1.86E-01	7.38E-01
Rheumatoid arthritis	FA20	Synovial tissue	1.28E-02	6.03E-01	1.40E+00
Rhinovirus infection	CA42.1	Nasal epithelium tissue	7.93E-01	7.32E-02	2.44E-01
Schizophrenia	6A20	Prefrontal cortex	1.27E-01	1.65E-01	2.87E-01
Schizophrenia	6A20	Superior temporal cortex	6.89E-01	2.05E-02	1.18E-01
Scleroderma	4A42.Z	Whole blood	2.11E-01	-2.21E-01	-4.80E-01
Seizure	8A60-8A6Z	Whole blood	8.28E-01	1.78E-01	2.74E-01
Sensitive skin	EK0Z	Skin	4.20E-01	-1.61E-01	-1.15E+00
Sepsis with septic shock	1G41	Whole blood	8.82E-70	-1.16E+00	-2.39E+00
Shwachman-Diamond syndrome	3A70.0	Bone marrow	1.59E-01	-2.15E-01	-4.29E-01
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	7.97E-03	1.51E-01	1.08E+00
Simpson golabi behmel syndrome	LD2C	Adipose tissue	9.31E-01	2.40E-01	3.15E-01
Sjogren's syndrome	4A43.2	Salivary gland tissue	9.20E-01	-7.17E-02	-2.71E-01
Skin cancer	2C30-2C3Z	Skin	7.34E-129	-2.01E+00	-4.20E+00
Thrombocythemia	3B63	Whole blood	4.01E-07	-3.59E-01	-1.78E+00
Thrombocytopenia	3B64	Whole blood	4.84E-01	2.53E-01	1.97E-01
Thyroid cancer	2D10	Thyroid	1.31E-33	-7.41E-01	-2.02E+00
Tibial muscular dystrophy	8C75	Muscle tissue	1.34E-01	-3.08E-01	-1.07E+00
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	6.33E-01	-1.30E-01	-4.74E-01
Type 2 diabetes	5A11	Liver tissue	4.31E-01	-2.84E-01	-1.23E+00
Ureter cancer	2C92	Urothelium	9.97E-01	-1.16E-02	-6.78E-02
Uterine cancer	2C78	Endometrium tissue	1.05E-03	-3.96E-01	-4.62E-01
Vitiligo	ED63.0	Skin	4.60E-01	-1.93E-01	-4.83E-01