Details of the Drug-Related molecule(s) Expression Atlas

General Information of DME (ID: DER8LQ6)

• DME Name: Phenylethanolamine N-methyltransferase (PNMT) DME Info
• Gene Name: PNMT

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	4.30E-01	-7.11E-02	-2.62E-01
Alopecia	ED70	Skin from scalp	6.23E-01	9.13E-03	4.02E-02
Alzheimer's disease	8A20	Entorhinal cortex	2.46E-01	-7.60E-03	-2.66E-02
Ankylosing spondylitis	FA92.0	Pheripheral blood	6.61E-01	-1.63E-03	-1.15E-02
Aortic stenosis	BB70	Calcified aortic valve	7.88E-01	-1.30E-01	-2.48E-01
Apnea	7A40	Hyperplastic tonsil	6.26E-01	-5.15E-02	-3.25E-01
Arthropathy	FA00-FA5Z	Peripheral blood	1.84E-01	3.62E-02	2.34E-01
Asthma	CA23	Nasal and bronchial airway	9.16E-03	-1.11E-01	-2.57E-01
Atopic dermatitis	EA80	Skin	2.96E-01	3.16E-02	2.02E-01
Autism	6A02	Whole blood	2.03E-01	-3.62E-02	-1.30E-01
Autoimmune uveitis	9A96	Peripheral monocyte	1.10E-01	-1.80E-01	-2.36E+00
Autosomal dominant monocytopenia	4B04	Whole blood	8.97E-01	-4.94E-03	-4.37E-02
Bacterial infection of gingival	1C1H	Gingival tissue	5.44E-01	-4.80E-02	-2.21E-01
Batten disease	5C56.1	Whole blood	6.65E-01	1.01E-01	1.02E+00
Behcet's disease	4A62	Peripheral blood	9.00E-01	-9.20E-02	-4.47E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	9.73E-03	-1.86E-01	-8.44E-01
Bladder cancer	2C94	Bladder tissue	9.98E-03	3.34E-02	1.44E-01
Breast cancer	2C60-2C6Z	Breast tissue	2.18E-26	2.07E-01	4.35E-01
Cardioembolic stroke	8B11.20	Whole blood	2.52E-02	1.40E-01	7.13E-01
Cervical cancer	2C77	Cervical tissue	9.75E-01	-2.32E-02	-1.19E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	7.75E-01	2.28E-02	6.75E-02
Chronic hepatitis C	1E51.1	Whole blood	9.67E-01	-6.32E-05	-4.25E-04
Chronic obstructive pulmonary disease	CA22	Lung tissue	8.92E-01	1.74E-02	6.96E-02
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	1.24E-01	7.62E-02	2.93E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	7.03E-01	-4.38E-02	-4.29E-01
Colon cancer	2B90	Colon tissue	6.76E-01	4.95E-03	2.15E-02
Coronary artery disease	BA80-BA8Z	Peripheral blood	5.95E-01	-1.00E-02	-2.53E-02
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	4.01E-01	-1.10E-01	-4.77E-01
Endometriosis	GA10	Endometrium tissue	2.24E-01	-1.33E-01	-5.43E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	9.44E-01	-2.52E-03	-1.40E-02
Familial hypercholesterolemia	5C80.00	Whole blood	1.76E-04	-4.18E-01	-1.28E+00
Gastric cancer	2B72	Gastric tissue	5.08E-01	1.08E-01	4.18E-01
Glioblastopma	2A00.00	Nervous tissue	1.36E-30	-3.68E-01	-1.10E+00
Glioma	2A00.0Y-2A00.0Z	Brain stem tissue	8.82E-01	-1.82E-01	-7.03E-01
Glioma	2A00.0Y-2A00.0Z	White matter tissue	1.77E-06	-7.54E-01	-2.96E+00
Head and neck cancer	2D42	Head and neck tissue	3.14E-02	1.08E-01	4.59E-01
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	9.58E-01	-1.97E-02	-4.87E-02
Huntington's disease	8A01.10	Whole blood	6.93E-02	1.36E-01	5.87E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	5.35E-02	-7.11E-01	-1.04E+00
Immunodeficiency	4A00-4A20	Peripheral blood	7.76E-01	1.66E-03	1.93E-02
Influenza	1E30	Whole blood	5.45E-03	2.56E-01	2.30E+00
Interstitial cystitis	GC00.3	Bladder tissue	5.19E-02	-2.78E-01	-1.33E+00
Intracranial aneurysm	8B01.0	Intracranial artery	9.35E-03	-3.17E-01	-9.04E-01
Irritable bowel syndrome	DD91.0	Rectal colon tissue	2.90E-01	-9.82E-03	-4.74E-02
Ischemic stroke	8B11	Peripheral blood	4.89E-01	-5.50E-02	-6.37E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	5.07E-01	-8.16E-03	-3.05E-02
Lateral sclerosis	8B60.4	Skin	7.65E-01	5.51E-02	3.03E-01
Lateral sclerosis	8B60.4	Cervical spinal cord	3.66E-01	7.96E-02	3.07E-01
Liver cancer	2C12.0	Liver tissue	4.46E-03	-2.24E-01	-8.54E-01
Liver failure	DB99.7-DB99.8	Liver tissue	2.80E-02	-3.03E-01	-1.24E+00
Lung cancer	2C25	Lung tissue	6.49E-10	-1.17E-01	-3.97E-01
Lupus erythematosus	4A40	Whole blood	2.49E-01	-9.45E-02	-2.09E-01
Major depressive disorder	6A70-6A7Z	Hippocampus	4.54E-01	-6.06E-02	-2.68E-01
Major depressive disorder	6A70-6A7Z	Whole blood	6.18E-02	-1.93E-02	-9.78E-02
Melanoma	2C30	Skin	1.02E-01	-9.11E-02	-2.88E-01
Multiple myeloma	2A83.1	Peripheral blood	4.13E-01	-6.95E-02	-5.47E-01
Multiple myeloma	2A83.1	Bone marrow	1.40E-01	-2.05E-01	-8.47E-01
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	2.84E-01	2.21E-02	6.95E-02
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	9.26E-02	5.88E-02	1.78E-01
Myelofibrosis	2A20.2	Whole blood	1.57E-01	5.19E-02	3.87E-01
Myocardial infarction	BA41-BA50	Peripheral blood	1.64E-01	4.04E-01	7.73E-01
Myopathy	8C70.6	Muscle tissue	8.48E-02	-1.70E-01	-1.51E+00
Neonatal sepsis	KA60	Whole blood	2.58E-01	-5.39E-02	-1.64E-01
Neuroectodermal tumour	2A00.11	Brain stem tissue	1.93E-01	-2.70E-01	-7.84E-01
Non-alcoholic fatty liver disease	DB92	Liver tissue	6.38E-01	-5.29E-02	-3.71E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	9.18E-01	2.97E-02	1.38E-01
Olive pollen allergy	CA08.00	Peripheral blood	4.44E-02	1.78E-01	1.28E+00
Oral cancer	2B6E	Oral tissue	2.35E-07	-3.38E-01	-1.05E+00
Osteoarthritis	FA00-FA0Z	Synovial tissue	4.20E-01	9.64E-02	2.32E-01
Osteoporosis	FB83.1	Bone marrow	2.50E-01	1.93E-01	6.60E-01
Ovarian cancer	2C73	Ovarian tissue	5.62E-01	-1.90E-01	-7.10E-01
Pancreatic cancer	2C10	Pancreas	7.06E-02	-1.48E-01	-4.19E-01
Parkinson's disease	8A00.0	Substantia nigra tissue	4.20E-01	2.46E-02	5.61E-02
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	5.81E-02	-1.27E-01	-6.43E-01
Pituitary cancer	2D12	Pituitary tissue	7.40E-02	-5.92E-01	-5.16E-01
Pituitary gonadotrope tumour	2D12	Pituitary tissue	1.12E-01	-4.08E-01	-3.47E-01
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	4.14E-01	8.46E-02	3.54E-01
Polycythemia vera	2A20.4	Whole blood	3.99E-02	5.41E-02	3.27E-01
Pompe disease	5C51.3	Biceps muscle	2.05E-05	-8.24E-01	-2.48E+00
Preterm birth	KA21.4Z	Myometrium	6.81E-01	1.73E-03	1.02E-02
Prostate cancer	2C82	Prostate	4.69E-01	-1.26E-01	-3.05E-01
Psoriasis	EA90	Skin	2.70E-03	-1.90E-01	-5.01E-01
Rectal cancer	2B92	Rectal colon tissue	3.37E-01	9.42E-02	5.96E-01
Renal cancer	2C90-2C91	Kidney	8.96E-02	-2.59E-01	-8.65E-01
Retinoblastoma	2D02.2	Uvea	1.54E-01	-2.93E-02	-1.89E-01
Rheumatoid arthritis	FA20	Synovial tissue	5.30E-02	-3.27E-01	-6.62E-01
Rhinovirus infection	CA42.1	Nasal epithelium tissue	5.60E-01	3.85E-02	2.85E-01
Schizophrenia	6A20	Prefrontal cortex	3.09E-01	-4.99E-02	-1.58E-01
Schizophrenia	6A20	Superior temporal cortex	6.91E-01	4.62E-02	2.93E-01
Scleroderma	4A42.Z	Whole blood	7.83E-03	3.06E-01	1.40E+00
Seizure	8A60-8A6Z	Whole blood	3.31E-01	-4.53E-02	-2.26E-01
Sensitive skin	EK0Z	Skin	2.74E-01	6.58E-03	5.61E-02
Sepsis with septic shock	1G41	Whole blood	2.19E-01	4.43E-02	1.60E-01
Shwachman-Diamond syndrome	3A70.0	Bone marrow	8.45E-01	2.80E-02	1.11E-01
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	4.71E-01	-1.14E-03	-5.62E-03
Simpson golabi behmel syndrome	LD2C	Adipose tissue	7.20E-01	9.76E-03	1.36E-01
Sjogren's syndrome	4A43.2	Salivary gland tissue	6.79E-01	-1.32E-01	-2.97E-01
Skin cancer	2C30-2C3Z	Skin	2.68E-08	-1.61E-01	-4.11E-01
Thrombocythemia	3B63	Whole blood	9.69E-01	-7.17E-04	-5.15E-03
Thrombocytopenia	3B64	Whole blood	3.72E-01	-5.93E-02	-1.37E-01
Thyroid cancer	2D10	Thyroid	1.68E-23	3.18E-01	1.34E+00
Tibial muscular dystrophy	8C75	Muscle tissue	5.02E-01	4.95E-02	2.39E-01
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	3.67E-01	-3.31E-01	-1.34E+00
Type 2 diabetes	5A11	Liver tissue	3.24E-01	-8.31E-05	-7.00E-04
Ureter cancer	2C92	Urothelium	6.69E-01	2.02E-02	9.14E-02
Uterine cancer	2C78	Endometrium tissue	2.69E-03	-9.57E-02	-2.82E-01
Vitiligo	ED63.0	Skin	2.81E-01	2.11E-02	2.75E-01