Details of the Drug-Related molecule(s) Expression Atlas

General Information of DME (ID: DEROYHE)

• DME Name: N-acetyl-D-glucosamine 2-epimerase (AGE) DME Info
• Gene Name: RENBP

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	1.47E-09	3.24E-01	7.88E-01
Alopecia	ED70	Skin from scalp	2.42E-03	1.06E-01	4.64E-01
Alzheimer's disease	8A20	Entorhinal cortex	4.55E-04	1.38E-01	5.14E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	3.83E-01	-4.37E-02	-1.17E-01
Aortic stenosis	BB70	Calcified aortic valve	5.54E-01	-9.28E-02	-1.97E-01
Apnea	7A40	Hyperplastic tonsil	3.47E-01	-2.90E-01	-8.17E-01
Arthropathy	FA00-FA5Z	Peripheral blood	8.69E-01	-4.90E-02	-1.72E-01
Asthma	CA23	Nasal and bronchial airway	3.54E-01	-1.16E-01	-1.97E-01
Atopic dermatitis	EA80	Skin	6.15E-01	-8.10E-02	-2.39E-01
Autism	6A02	Whole blood	1.56E-01	-1.75E-02	-3.62E-02
Autoimmune uveitis	9A96	Peripheral monocyte	7.51E-02	4.43E-01	3.30E+00
Autosomal dominant monocytopenia	4B04	Whole blood	2.05E-02	1.19E-01	2.82E-01
Bacterial infection of gingival	1C1H	Gingival tissue	3.32E-03	1.83E-01	4.08E-01
Batten disease	5C56.1	Whole blood	3.18E-01	1.93E-01	9.36E-01
Behcet's disease	4A62	Peripheral blood	3.22E-01	3.58E-01	1.02E+00
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	1.30E-01	-9.90E-02	-4.46E-01
Bladder cancer	2C94	Bladder tissue	1.90E-04	1.16E+00	2.80E+00
Breast cancer	2C60-2C6Z	Breast tissue	6.34E-01	-8.96E-02	-1.14E-01
Cardioembolic stroke	8B11.20	Whole blood	8.49E-02	-1.18E-01	-3.87E-01
Cervical cancer	2C77	Cervical tissue	2.16E-02	1.44E-01	5.82E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	9.47E-01	9.13E-02	1.07E-01
Chronic hepatitis C	1E51.1	Whole blood	1.52E-01	2.02E-01	8.87E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	8.09E-01	-4.67E-02	-9.80E-02
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	1.59E-01	1.27E-01	3.96E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	1.59E-02	2.44E-01	1.23E+00
Colon cancer	2B90	Colon tissue	5.21E-03	-1.22E-01	-3.15E-01
Coronary artery disease	BA80-BA8Z	Peripheral blood	3.43E-01	-1.07E-01	-8.80E-01
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	5.02E-01	-1.56E-01	-6.44E-01
Endometriosis	GA10	Endometrium tissue	2.29E-01	1.33E-01	1.90E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	8.19E-02	-2.68E-02	-1.30E-01
Familial hypercholesterolemia	5C80.00	Whole blood	3.44E-10	7.37E-01	2.24E+00
Gastric cancer	2B72	Gastric tissue	3.37E-01	-2.42E-01	-1.59E+00
Glioblastopma	2A00.00	Nervous tissue	6.20E-04	-3.25E-01	-6.01E-01
Glioma	2A00.0Y-2A00.0Z	Brain stem tissue	7.73E-01	-1.31E-01	-4.66E-01
Glioma	2A00.0Y-2A00.0Z	White matter tissue	9.83E-01	-4.10E-02	-1.09E-01
Head and neck cancer	2D42	Head and neck tissue	1.51E-04	1.35E-01	4.74E-01
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	6.93E-01	5.55E-02	1.61E-01
Huntington's disease	8A01.10	Whole blood	8.13E-01	6.88E-02	1.59E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	8.75E-02	2.69E-01	9.10E-01
Immunodeficiency	4A00-4A20	Peripheral blood	4.05E-02	1.30E-01	1.61E+00
Influenza	1E30	Whole blood	2.22E-01	2.37E-01	1.30E+00
Interstitial cystitis	GC00.3	Bladder tissue	3.23E-01	4.30E-01	9.22E-01
Intracranial aneurysm	8B01.0	Intracranial artery	1.20E-01	4.83E-01	1.13E+00
Irritable bowel syndrome	DD91.0	Rectal colon tissue	3.69E-01	4.45E-02	1.44E-01
Ischemic stroke	8B11	Peripheral blood	4.56E-02	-3.17E-01	-9.73E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	4.07E-01	-5.50E-02	-1.76E-01
Lateral sclerosis	8B60.4	Skin	3.01E-01	1.60E-01	7.52E-01
Lateral sclerosis	8B60.4	Cervical spinal cord	6.18E-02	-1.68E-01	-8.02E-01
Liver cancer	2C12.0	Liver tissue	9.74E-01	-8.97E-02	-2.50E-01
Liver failure	DB99.7-DB99.8	Liver tissue	9.37E-05	5.51E-01	3.09E+00
Lung cancer	2C25	Lung tissue	5.38E-27	-4.75E-01	-9.09E-01
Lupus erythematosus	4A40	Whole blood	9.34E-01	-2.36E-02	-3.49E-02
Major depressive disorder	6A70-6A7Z	Hippocampus	5.97E-01	-7.47E-02	-3.48E-01
Major depressive disorder	6A70-6A7Z	Whole blood	1.81E-01	-1.77E-02	-3.81E-02
Melanoma	2C30	Skin	1.26E-04	1.84E+00	1.35E+00
Multiple myeloma	2A83.1	Peripheral blood	2.29E-01	1.23E-01	5.47E-01
Multiple myeloma	2A83.1	Bone marrow	5.04E-06	-7.86E-01	-3.85E+00
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	8.90E-01	9.37E-02	2.70E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	2.97E-01	4.62E-02	1.30E-01
Myelofibrosis	2A20.2	Whole blood	2.62E-03	-2.57E-01	-1.27E+00
Myocardial infarction	BA41-BA50	Peripheral blood	2.27E-02	4.12E-01	6.58E-01
Myopathy	8C70.6	Muscle tissue	2.40E-01	1.64E-01	5.70E-01
Neonatal sepsis	KA60	Whole blood	2.03E-17	7.42E-01	1.34E+00
Neuroectodermal tumour	2A00.11	Brain stem tissue	6.03E-07	-2.11E+00	-3.91E+00
Non-alcoholic fatty liver disease	DB92	Liver tissue	7.60E-01	6.26E-03	4.27E-02
Obesity related type 2 diabetes	5A11	Omental adipose tissue	3.99E-01	1.02E-01	8.01E-01
Olive pollen allergy	CA08.00	Peripheral blood	1.62E-04	5.10E-01	7.21E+00
Oral cancer	2B6E	Oral tissue	2.13E-03	-4.00E-01	-1.05E+00
Osteoarthritis	FA00-FA0Z	Synovial tissue	6.07E-01	-1.30E-02	-3.14E-02
Osteoporosis	FB83.1	Bone marrow	5.63E-02	3.47E-01	2.55E+00
Ovarian cancer	2C73	Ovarian tissue	3.51E-01	8.00E-03	1.72E-02
Pancreatic cancer	2C10	Pancreas	6.42E-01	-9.03E-02	-1.87E-01
Parkinson's disease	8A00.0	Substantia nigra tissue	2.00E-01	-1.49E-01	-5.39E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	2.37E-04	4.38E-01	1.16E+00
Pituitary cancer	2D12	Pituitary tissue	9.65E-01	1.14E-01	2.41E-01
Pituitary gonadotrope tumour	2D12	Pituitary tissue	6.64E-01	-6.47E-02	-1.34E-01
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	9.69E-01	-2.82E-02	-2.61E-01
Polycythemia vera	2A20.4	Whole blood	3.00E-03	-1.13E-01	-5.52E-01
Pompe disease	5C51.3	Biceps muscle	5.74E-02	1.60E-01	1.37E+00
Preterm birth	KA21.4Z	Myometrium	6.35E-01	-1.01E-01	-2.90E-01
Prostate cancer	2C82	Prostate	3.50E-07	-1.63E+00	-2.08E+00
Psoriasis	EA90	Skin	3.68E-12	-4.02E-01	-5.51E-01
Rectal cancer	2B92	Rectal colon tissue	1.07E-02	-3.44E-01	-1.58E+00
Renal cancer	2C90-2C91	Kidney	1.17E-02	-1.09E+00	-1.23E+00
Retinoblastoma	2D02.2	Uvea	1.03E-09	2.15E+00	9.31E+00
Rheumatoid arthritis	FA20	Synovial tissue	7.78E-04	1.11E+00	3.01E+00
Rhinovirus infection	CA42.1	Nasal epithelium tissue	1.30E-01	1.89E-02	1.35E-01
Schizophrenia	6A20	Prefrontal cortex	5.81E-01	1.75E-01	3.06E-01
Schizophrenia	6A20	Superior temporal cortex	1.34E-01	-1.07E-01	-5.80E-01
Scleroderma	4A42.Z	Whole blood	3.10E-02	1.34E-01	5.94E-01
Seizure	8A60-8A6Z	Whole blood	5.90E-01	-9.41E-03	-3.46E-02
Sensitive skin	EK0Z	Skin	5.90E-01	1.95E-02	7.15E-02
Sepsis with septic shock	1G41	Whole blood	2.07E-41	5.02E-01	1.45E+00
Shwachman-Diamond syndrome	3A70.0	Bone marrow	1.25E-01	3.25E-01	1.09E+00
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	7.72E-02	6.85E-02	3.13E-01
Simpson golabi behmel syndrome	LD2C	Adipose tissue	9.65E-01	1.71E-02	4.63E-01
Sjogren's syndrome	4A43.2	Salivary gland tissue	8.16E-01	-3.94E-02	-1.71E-01
Skin cancer	2C30-2C3Z	Skin	2.47E-08	3.96E-01	4.54E-01
Thrombocythemia	3B63	Whole blood	1.54E-02	-1.40E-01	-7.19E-01
Thrombocytopenia	3B64	Whole blood	8.18E-01	-2.38E-01	-4.42E-01
Thyroid cancer	2D10	Thyroid	1.46E-20	4.82E-01	1.32E+00
Tibial muscular dystrophy	8C75	Muscle tissue	1.46E-01	3.55E-02	1.60E-01
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	1.78E-02	1.02E+00	3.93E+00
Type 2 diabetes	5A11	Liver tissue	4.99E-01	-1.36E-01	-2.83E-01
Ureter cancer	2C92	Urothelium	6.76E-01	6.77E-03	2.75E-02
Uterine cancer	2C78	Endometrium tissue	9.73E-01	-5.15E-02	-1.04E-01
Vitiligo	ED63.0	Skin	6.65E-01	1.50E-01	4.67E-01