Details of the Drug-Related molecule(s) Expression Atlas

General Information of DME (ID: DESO5ZY)

• DME Name: Prolyl 4-hydroxylase alpha-1 (P4HA1) DME Info
• Gene Name: P4HA1

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	2.83E-22	2.79E-01	1.29E+00
Alopecia	ED70	Skin from scalp	1.80E-01	1.47E-02	7.72E-02
Alzheimer's disease	8A20	Entorhinal cortex	2.64E-04	8.06E-02	3.08E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	5.44E-02	-1.63E-01	-5.29E-01
Aortic stenosis	BB70	Calcified aortic valve	3.29E-01	4.55E-02	2.78E-01
Apnea	7A40	Hyperplastic tonsil	9.51E-02	3.64E-01	2.03E+00
Arthropathy	FA00-FA5Z	Peripheral blood	8.29E-01	-5.89E-03	-5.54E-02
Asthma	CA23	Nasal and bronchial airway	3.37E-08	-3.40E-01	-3.42E-01
Atopic dermatitis	EA80	Skin	1.99E-02	-2.07E-01	-1.20E+00
Autism	6A02	Whole blood	3.12E-01	-5.98E-02	-3.48E-01
Autoimmune uveitis	9A96	Peripheral monocyte	6.43E-01	1.50E-02	1.25E-01
Autosomal dominant monocytopenia	4B04	Whole blood	9.42E-02	2.44E-01	1.13E+00
Bacterial infection of gingival	1C1H	Gingival tissue	1.32E-04	1.40E-01	6.11E-01
Batten disease	5C56.1	Whole blood	2.50E-01	-1.22E-01	-1.06E+00
Behcet's disease	4A62	Peripheral blood	8.82E-01	-6.61E-03	-3.37E-02
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	5.19E-01	4.17E-03	2.53E-02
Bladder cancer	2C94	Bladder tissue	9.22E-01	-5.33E-03	-2.90E-02
Breast cancer	2C60-2C6Z	Breast tissue	2.11E-41	2.84E-01	1.05E+00
Cardioembolic stroke	8B11.20	Whole blood	2.22E-07	4.18E-01	1.92E+00
Cervical cancer	2C77	Cervical tissue	8.51E-02	1.30E-01	3.70E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	5.95E-02	-8.59E-02	-4.56E-01
Chronic hepatitis C	1E51.1	Whole blood	3.75E-02	-1.67E-01	-1.52E+00
Chronic obstructive pulmonary disease	CA22	Lung tissue	1.56E-01	3.73E-02	1.58E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	7.76E-01	-1.92E-02	-8.12E-02
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	8.30E-01	-7.12E-02	-2.79E-01
Colon cancer	2B90	Colon tissue	6.92E-47	4.01E-01	1.71E+00
Coronary artery disease	BA80-BA8Z	Peripheral blood	1.39E-01	-1.98E-01	-8.99E-01
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	9.57E-01	-9.39E-02	-3.86E-01
Endometriosis	GA10	Endometrium tissue	7.52E-01	-3.98E-02	-1.01E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	3.01E-01	-2.29E-02	-1.64E-01
Familial hypercholesterolemia	5C80.00	Whole blood	5.76E-12	6.20E-01	1.97E+00
Gastric cancer	2B72	Gastric tissue	9.44E-02	8.82E-02	1.02E+00
Glioblastopma	2A00.00	Nervous tissue	7.44E-65	4.34E-01	1.37E+00
Glioma	2A00.0Y-2A00.0Z	Brain stem tissue	9.19E-01	3.21E-02	2.66E-02
Glioma	2A00.0Y-2A00.0Z	White matter tissue	7.01E-02	2.44E-01	8.51E-01
Head and neck cancer	2D42	Head and neck tissue	5.74E-09	3.38E-01	7.62E-01
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	3.04E-01	-2.14E-02	-4.90E-02
Huntington's disease	8A01.10	Whole blood	3.47E-01	-2.78E-02	-1.80E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	1.60E-01	-2.14E-01	-1.11E+00
Immunodeficiency	4A00-4A20	Peripheral blood	1.43E-02	-7.57E-02	-7.73E-01
Influenza	1E30	Whole blood	5.44E-01	-1.87E-01	-5.34E-01
Interstitial cystitis	GC00.3	Bladder tissue	1.30E-01	-1.55E-01	-1.31E+00
Intracranial aneurysm	8B01.0	Intracranial artery	9.25E-07	4.54E-01	2.76E+00
Irritable bowel syndrome	DD91.0	Rectal colon tissue	1.77E-01	-5.83E-03	-2.09E-02
Ischemic stroke	8B11	Peripheral blood	3.51E-01	-3.93E-02	-3.44E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	2.28E-02	5.16E-02	2.58E-01
Lateral sclerosis	8B60.4	Skin	1.87E-01	-7.49E-02	-7.36E-01
Lateral sclerosis	8B60.4	Cervical spinal cord	2.92E-01	1.66E-01	6.54E-01
Liver cancer	2C12.0	Liver tissue	7.08E-04	-3.80E-01	-7.33E-01
Liver failure	DB99.7-DB99.8	Liver tissue	1.21E-03	-9.87E-01	-1.77E+00
Lung cancer	2C25	Lung tissue	2.77E-53	4.93E-01	1.79E+00
Lupus erythematosus	4A40	Whole blood	1.19E-01	9.20E-02	1.99E-01
Major depressive disorder	6A70-6A7Z	Hippocampus	4.31E-02	-4.26E-02	-2.86E-01
Major depressive disorder	6A70-6A7Z	Whole blood	4.82E-01	3.00E-02	1.34E-01
Melanoma	2C30	Skin	8.18E-01	2.73E-01	5.55E-01
Multiple myeloma	2A83.1	Peripheral blood	6.25E-01	2.33E-02	1.18E-01
Multiple myeloma	2A83.1	Bone marrow	6.39E-01	-1.71E-01	-7.52E-01
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	4.72E-01	-1.42E-01	-8.47E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	8.16E-01	3.91E-02	1.47E-01
Myelofibrosis	2A20.2	Whole blood	9.47E-01	1.55E-02	1.37E-01
Myocardial infarction	BA41-BA50	Peripheral blood	3.90E-01	-2.78E-02	-3.79E-02
Myopathy	8C70.6	Muscle tissue	1.94E-01	-9.14E-02	-7.03E-01
Neonatal sepsis	KA60	Whole blood	3.03E-10	2.43E-01	1.09E+00
Neuroectodermal tumour	2A00.11	Brain stem tissue	1.37E-02	2.26E-01	1.65E+00
Non-alcoholic fatty liver disease	DB92	Liver tissue	1.03E-01	-1.05E+00	-1.54E+00
Obesity related type 2 diabetes	5A11	Omental adipose tissue	7.85E-01	-5.54E-02	-3.37E-01
Olive pollen allergy	CA08.00	Peripheral blood	2.02E-01	4.35E-01	1.27E+00
Oral cancer	2B6E	Oral tissue	4.77E-06	6.01E-01	1.28E+00
Osteoarthritis	FA00-FA0Z	Synovial tissue	8.08E-01	2.36E-01	3.79E-01
Osteoporosis	FB83.1	Bone marrow	2.10E-01	3.19E-01	1.38E+00
Ovarian cancer	2C73	Ovarian tissue	2.10E-03	2.34E-01	1.20E+00
Pancreatic cancer	2C10	Pancreas	8.91E-12	4.21E-01	2.88E+00
Parkinson's disease	8A00.0	Substantia nigra tissue	5.80E-05	4.44E-01	2.49E+00
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	4.24E-01	-2.28E-02	-1.93E-01
Pituitary cancer	2D12	Pituitary tissue	4.14E-02	6.39E-01	1.33E+00
Pituitary gonadotrope tumour	2D12	Pituitary tissue	6.83E-02	6.31E-01	1.30E+00
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	9.51E-01	-1.02E-02	-4.99E-02
Polycythemia vera	2A20.4	Whole blood	2.68E-03	6.36E-02	6.42E-01
Pompe disease	5C51.3	Biceps muscle	2.90E-01	-2.40E-01	-1.21E+00
Preterm birth	KA21.4Z	Myometrium	4.09E-02	-1.93E-01	-8.42E-01
Prostate cancer	2C82	Prostate	5.62E-04	3.49E-01	7.68E-01
Psoriasis	EA90	Skin	6.53E-19	-2.88E-01	-1.14E+00
Rectal cancer	2B92	Rectal colon tissue	7.24E-02	3.31E-01	1.26E+00
Renal cancer	2C90-2C91	Kidney	5.76E-07	7.57E-01	3.18E+00
Retinoblastoma	2D02.2	Uvea	2.47E-07	6.97E-01	2.65E+00
Rheumatoid arthritis	FA20	Synovial tissue	1.55E-01	-1.20E-01	-6.87E-01
Rhinovirus infection	CA42.1	Nasal epithelium tissue	8.91E-01	-5.57E-02	-2.67E-01
Schizophrenia	6A20	Prefrontal cortex	3.15E-04	2.22E-01	8.28E-01
Schizophrenia	6A20	Superior temporal cortex	2.64E-01	7.50E-02	4.13E-01
Scleroderma	4A42.Z	Whole blood	1.43E-01	6.87E-02	6.77E-01
Seizure	8A60-8A6Z	Whole blood	5.29E-02	1.23E-01	8.43E-01
Sensitive skin	EK0Z	Skin	1.70E-01	-7.52E-02	-1.10E+00
Sepsis with septic shock	1G41	Whole blood	1.62E-24	2.18E-01	9.50E-01
Shwachman-Diamond syndrome	3A70.0	Bone marrow	3.03E-02	-2.78E-01	-1.37E+00
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	4.51E-02	-2.31E-01	-4.49E-01
Simpson golabi behmel syndrome	LD2C	Adipose tissue	4.34E-03	5.73E-01	4.48E+00
Sjogren's syndrome	4A43.2	Salivary gland tissue	1.98E-02	2.06E-01	2.72E+00
Skin cancer	2C30-2C3Z	Skin	5.22E-30	3.57E-01	1.41E+00
Thrombocythemia	3B63	Whole blood	1.33E-01	-5.02E-02	-4.61E-01
Thrombocytopenia	3B64	Whole blood	6.31E-01	-1.22E-01	-1.88E-01
Thyroid cancer	2D10	Thyroid	3.36E-30	3.39E-01	1.84E+00
Tibial muscular dystrophy	8C75	Muscle tissue	3.48E-04	-3.74E-01	-1.98E+00
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	4.60E-01	-1.16E-03	-7.32E-03
Type 2 diabetes	5A11	Liver tissue	7.56E-01	-1.69E-02	-3.80E-02
Ureter cancer	2C92	Urothelium	6.51E-01	-5.14E-02	-1.53E-01
Uterine cancer	2C78	Endometrium tissue	1.07E-01	9.21E-02	2.30E-01
Vitiligo	ED63.0	Skin	9.47E-02	5.13E-02	5.77E-01