Details of the Drug-Related molecule(s) Expression Atlas

General Information of DME (ID: DETXQZ1)

• DME Name: Serum paraoxonase/lactonase 3 (PON3) DME Info
• Gene Name: PON3

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	2.60E-04	-1.17E-01	-4.77E-01
Alopecia	ED70	Skin from scalp	4.12E-03	2.41E-01	4.92E-01
Alzheimer's disease	8A20	Entorhinal cortex	2.07E-03	2.39E-01	5.38E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	7.06E-01	2.87E-03	2.91E-02
Aortic stenosis	BB70	Calcified aortic valve	6.18E-01	-3.36E-03	-5.63E-03
Apnea	7A40	Hyperplastic tonsil	2.92E-01	2.35E-01	2.33E+00
Arthropathy	FA00-FA5Z	Peripheral blood	9.69E-01	-2.14E-02	-1.69E-01
Asthma	CA23	Nasal and bronchial airway	6.45E-08	5.09E-01	6.66E-01
Atopic dermatitis	EA80	Skin	6.80E-03	-4.06E-01	-5.32E-01
Autism	6A02	Whole blood	7.24E-02	-9.43E-02	-5.52E-01
Autoimmune uveitis	9A96	Peripheral monocyte	6.24E-02	-2.85E-01	-2.00E+00
Autosomal dominant monocytopenia	4B04	Whole blood	4.87E-01	6.54E-02	3.59E-01
Bacterial infection of gingival	1C1H	Gingival tissue	1.49E-01	-6.16E-02	-2.16E-01
Batten disease	5C56.1	Whole blood	2.51E-01	5.80E-02	3.22E-01
Behcet's disease	4A62	Peripheral blood	3.10E-01	1.67E-01	7.88E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	9.18E-01	1.65E-02	4.58E-02
Bladder cancer	2C94	Bladder tissue	8.14E-04	-1.49E+00	-2.33E+00
Breast cancer	2C60-2C6Z	Breast tissue	1.80E-20	-9.67E-01	-9.36E-01
Cardioembolic stroke	8B11.20	Whole blood	2.50E-01	1.35E-02	6.89E-02
Cervical cancer	2C77	Cervical tissue	1.30E-02	5.29E-01	7.09E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	3.50E-01	7.91E-02	2.88E-01
Chronic hepatitis C	1E51.1	Whole blood	3.49E-01	3.44E-02	1.87E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	9.54E-01	-2.07E-02	-6.36E-02
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	3.34E-01	1.96E-01	2.76E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	4.45E-01	-4.32E-02	-2.43E-01
Colon cancer	2B90	Colon tissue	2.88E-01	-1.08E-01	-2.42E-01
Coronary artery disease	BA80-BA8Z	Peripheral blood	6.06E-01	-6.80E-03	-4.48E-02
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	8.50E-01	-4.73E-02	-2.89E-01
Endometriosis	GA10	Endometrium tissue	3.95E-03	2.19E-02	7.92E-02
Familial hypercholesterolemia	5C80.00	Peripheral blood	6.92E-01	8.68E-02	4.16E-01
Familial hypercholesterolemia	5C80.00	Whole blood	2.30E-02	-3.44E-01	-1.20E+00
Gastric cancer	2B72	Gastric tissue	8.62E-01	1.69E-01	1.74E-01
Glioblastopma	2A00.00	Nervous tissue	3.42E-01	-1.08E-01	-1.96E-01
Glioma	2A00.0Y-2A00.0Z	Brain stem tissue	5.57E-01	-8.76E-02	-1.54E+00
Glioma	2A00.0Y-2A00.0Z	White matter tissue	4.17E-01	-7.23E-02	-2.05E-01
Head and neck cancer	2D42	Head and neck tissue	6.70E-08	-8.33E-01	-6.93E-01
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	2.27E-01	8.93E-02	2.80E-01
Huntington's disease	8A01.10	Whole blood	2.36E-01	4.46E-02	2.55E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	3.10E-01	6.18E-02	1.53E-01
Immunodeficiency	4A00-4A20	Peripheral blood	1.79E-01	8.75E-02	6.61E-01
Influenza	1E30	Whole blood	2.30E-02	1.84E-01	3.50E+00
Interstitial cystitis	GC00.3	Bladder tissue	1.30E-03	-1.23E+00	-2.22E+00
Intracranial aneurysm	8B01.0	Intracranial artery	1.87E-03	-5.89E-01	-1.23E+00
Irritable bowel syndrome	DD91.0	Rectal colon tissue	7.10E-02	1.17E-01	4.55E-01
Ischemic stroke	8B11	Peripheral blood	6.75E-01	6.00E-02	3.02E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	1.61E-05	2.01E-01	8.08E-01
Lateral sclerosis	8B60.4	Skin	7.34E-01	3.87E-02	7.15E-01
Lateral sclerosis	8B60.4	Cervical spinal cord	5.46E-01	7.63E-02	1.67E-01
Liver cancer	2C12.0	Liver tissue	4.29E-52	-1.69E+00	-4.82E+00
Liver failure	DB99.7-DB99.8	Liver tissue	4.29E-05	-4.71E+00	-1.81E+01
Lung cancer	2C25	Lung tissue	4.44E-08	-2.47E-01	-4.46E-01
Lupus erythematosus	4A40	Whole blood	2.65E-01	-3.79E-03	-6.65E-03
Major depressive disorder	6A70-6A7Z	Hippocampus	6.94E-01	5.65E-02	1.76E-01
Major depressive disorder	6A70-6A7Z	Whole blood	5.04E-01	3.32E-02	9.99E-02
Melanoma	2C30	Skin	4.94E-04	-2.63E+00	-1.20E+00
Multiple myeloma	2A83.1	Peripheral blood	4.95E-01	2.88E-02	1.37E-01
Multiple myeloma	2A83.1	Bone marrow	1.22E-01	-2.02E-01	-7.28E-01
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	1.16E-01	2.83E-01	8.72E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	1.30E-01	6.37E-02	2.32E-01
Myelofibrosis	2A20.2	Whole blood	2.69E-02	3.45E-01	1.74E+00
Myocardial infarction	BA41-BA50	Peripheral blood	2.10E-02	2.97E-01	5.00E-01
Myopathy	8C70.6	Muscle tissue	2.35E-01	-8.10E-02	-3.32E-01
Neonatal sepsis	KA60	Whole blood	6.90E-02	-1.94E-02	-6.13E-02
Neuroectodermal tumour	2A00.11	Brain stem tissue	2.00E-08	-1.38E+00	-4.28E+00
Non-alcoholic fatty liver disease	DB92	Liver tissue	8.98E-01	-3.38E-02	-8.36E-02
Obesity related type 2 diabetes	5A11	Omental adipose tissue	2.86E-01	-2.18E-01	-3.43E-01
Olive pollen allergy	CA08.00	Peripheral blood	2.87E-01	-9.30E-03	-4.07E-02
Oral cancer	2B6E	Oral tissue	5.71E-01	-1.63E-02	-1.17E-02
Osteoarthritis	FA00-FA0Z	Synovial tissue	4.13E-01	4.70E-02	1.29E-01
Osteoporosis	FB83.1	Bone marrow	4.19E-01	-1.29E-02	-5.40E-02
Ovarian cancer	2C73	Ovarian tissue	4.03E-05	-3.21E+00	-3.20E+00
Pancreatic cancer	2C10	Pancreas	9.81E-01	-3.02E-01	-2.87E-01
Parkinson's disease	8A00.0	Substantia nigra tissue	3.39E-01	-3.69E-01	-7.95E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	9.09E-03	9.27E-02	7.83E-01
Pituitary cancer	2D12	Pituitary tissue	8.70E-13	-4.81E+00	-9.01E+00
Pituitary gonadotrope tumour	2D12	Pituitary tissue	1.36E-04	-4.23E+00	-9.09E+00
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	3.62E-02	1.57E-01	1.09E+00
Polycythemia vera	2A20.4	Whole blood	1.37E-04	1.09E-01	5.62E-01
Pompe disease	5C51.3	Biceps muscle	2.28E-03	8.05E-01	2.45E+00
Preterm birth	KA21.4Z	Myometrium	8.97E-01	-3.49E-02	-1.33E-01
Prostate cancer	2C82	Prostate	9.95E-08	-1.24E+00	-1.85E+00
Psoriasis	EA90	Skin	1.20E-03	4.79E-01	6.30E-01
Rectal cancer	2B92	Rectal colon tissue	6.93E-03	-6.10E-01	-1.62E+00
Renal cancer	2C90-2C91	Kidney	9.88E-07	-9.50E-01	-3.24E+00
Retinoblastoma	2D02.2	Uvea	4.85E-02	2.61E-01	1.84E+00
Rheumatoid arthritis	FA20	Synovial tissue	3.95E-01	-1.76E-01	-4.32E-01
Rhinovirus infection	CA42.1	Nasal epithelium tissue	6.62E-01	1.45E-02	4.15E-02
Schizophrenia	6A20	Prefrontal cortex	9.35E-01	-1.15E-02	-2.69E-02
Schizophrenia	6A20	Superior temporal cortex	2.01E-01	1.86E-02	9.79E-02
Scleroderma	4A42.Z	Whole blood	9.17E-01	2.24E-02	9.53E-02
Seizure	8A60-8A6Z	Whole blood	6.35E-01	-1.82E-02	-6.56E-02
Sensitive skin	EK0Z	Skin	5.07E-01	-5.75E-02	-1.71E-01
Sepsis with septic shock	1G41	Whole blood	8.17E-01	3.64E-02	1.35E-01
Shwachman-Diamond syndrome	3A70.0	Bone marrow	4.38E-02	2.37E-01	5.59E-01
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	9.21E-01	8.60E-02	3.17E-01
Simpson golabi behmel syndrome	LD2C	Adipose tissue	5.71E-01	-7.92E-03	-9.18E-02
Sjogren's syndrome	4A43.2	Salivary gland tissue	1.00E-01	-9.40E-01	-1.32E+00
Skin cancer	2C30-2C3Z	Skin	4.95E-76	-2.18E+00	-2.32E+00
Thrombocythemia	3B63	Whole blood	9.06E-02	1.18E-01	5.91E-01
Thrombocytopenia	3B64	Whole blood	3.25E-01	2.02E-01	5.53E-01
Thyroid cancer	2D10	Thyroid	1.68E-18	-1.02E+00	-1.29E+00
Tibial muscular dystrophy	8C75	Muscle tissue	4.51E-05	5.90E-01	1.93E+00
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	4.27E-01	2.96E-01	6.49E-01
Type 2 diabetes	5A11	Liver tissue	3.48E-01	-2.10E-01	-7.25E-01
Ureter cancer	2C92	Urothelium	9.11E-01	-9.73E-03	-4.48E-02
Uterine cancer	2C78	Endometrium tissue	9.58E-01	-2.49E-01	-4.00E-01
Vitiligo	ED63.0	Skin	6.92E-01	-6.68E-01	-1.05E+00