Details of the Drug-Related molecule(s) Expression Atlas

General Information of DME (ID: DETYWG5)

• DME Name: UDP-N-acetylhexosamine pyrophosphorylase (AGX) DME Info
• Gene Name: UAP1

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	3.98E-03	-3.57E-02	-5.29E-02
Alopecia	ED70	Skin from scalp	5.65E-05	1.44E-01	7.49E-01
Alzheimer's disease	8A20	Entorhinal cortex	2.64E-03	-1.54E-01	-3.81E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	3.23E-01	-1.97E-01	-8.41E-01
Aortic stenosis	BB70	Calcified aortic valve	9.95E-01	1.14E-01	6.24E-02
Apnea	7A40	Hyperplastic tonsil	3.00E-01	-5.43E-01	-4.42E-01
Arthropathy	FA00-FA5Z	Peripheral blood	8.86E-02	-2.30E-01	-6.28E-01
Asthma	CA23	Nasal and bronchial airway	5.41E-10	5.05E-01	6.11E-01
Atopic dermatitis	EA80	Skin	3.55E-01	4.86E-02	1.86E-01
Autism	6A02	Whole blood	5.13E-01	-1.27E-01	-2.30E-01
Autoimmune uveitis	9A96	Peripheral monocyte	5.57E-01	-6.20E-01	-1.03E+00
Autosomal dominant monocytopenia	4B04	Whole blood	6.31E-01	4.94E-01	6.07E-01
Bacterial infection of gingival	1C1H	Gingival tissue	7.31E-06	4.66E-01	8.34E-01
Batten disease	5C56.1	Whole blood	1.43E-01	1.60E-01	1.06E+00
Behcet's disease	4A62	Peripheral blood	5.45E-01	-1.64E-01	-6.01E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	6.23E-01	3.48E-02	1.28E-01
Bladder cancer	2C94	Bladder tissue	9.97E-01	2.88E-02	7.83E-02
Breast cancer	2C60-2C6Z	Breast tissue	4.40E-24	4.23E-01	6.36E-01
Cardioembolic stroke	8B11.20	Whole blood	5.30E-04	-2.39E-01	-1.20E+00
Cervical cancer	2C77	Cervical tissue	6.64E-01	8.43E-03	1.39E-02
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	1.73E-01	-3.60E-01	-4.78E-01
Chronic hepatitis C	1E51.1	Whole blood	9.30E-01	2.04E-01	2.63E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	7.59E-01	1.46E-03	1.81E-03
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	4.10E-05	-2.09E-01	-6.83E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	2.86E-01	-6.29E-01	-7.92E-01
Colon cancer	2B90	Colon tissue	2.62E-94	-7.97E-01	-2.94E+00
Coronary artery disease	BA80-BA8Z	Peripheral blood	1.33E-02	1.58E+00	2.57E+00
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	6.20E-01	-1.36E-01	-2.54E-01
Endometriosis	GA10	Endometrium tissue	4.80E-02	3.83E-01	7.46E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	8.73E-01	-3.28E-02	-8.75E-02
Familial hypercholesterolemia	5C80.00	Whole blood	6.88E-01	-3.04E-02	-6.99E-02
Gastric cancer	2B72	Gastric tissue	8.74E-01	-2.98E-01	-4.65E-01
Glioblastopma	2A00.00	Nervous tissue	6.46E-21	4.26E-01	5.29E-01
Glioma	2A00.0Y-2A00.0Z	Brain stem tissue	7.85E-01	6.17E-02	6.95E-02
Glioma	2A00.0Y-2A00.0Z	White matter tissue	6.39E-03	3.30E-01	1.00E+00
Head and neck cancer	2D42	Head and neck tissue	2.22E-09	-5.10E-01	-6.25E-01
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	7.08E-01	-4.15E-02	-6.45E-02
Huntington's disease	8A01.10	Whole blood	9.68E-02	-5.58E-01	-1.15E+00
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	5.05E-01	1.18E-01	1.44E-01
Immunodeficiency	4A00-4A20	Peripheral blood	6.24E-03	-2.72E-01	-1.71E+00
Influenza	1E30	Whole blood	1.01E-02	-8.96E-01	-3.58E+00
Interstitial cystitis	GC00.3	Bladder tissue	4.36E-02	4.37E-01	1.48E+00
Intracranial aneurysm	8B01.0	Intracranial artery	6.70E-01	1.55E-02	1.80E-02
Irritable bowel syndrome	DD91.0	Rectal colon tissue	7.43E-01	1.13E-02	6.87E-02
Ischemic stroke	8B11	Peripheral blood	8.53E-01	1.22E-01	2.60E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	3.81E-01	1.16E-01	2.08E-01
Lateral sclerosis	8B60.4	Skin	9.62E-01	1.51E-02	5.53E-02
Lateral sclerosis	8B60.4	Cervical spinal cord	1.21E-01	-3.50E-01	-4.96E-01
Liver cancer	2C12.0	Liver tissue	8.82E-05	-3.44E-01	-7.26E-01
Liver failure	DB99.7-DB99.8	Liver tissue	1.55E-05	-9.99E-01	-3.42E+00
Lung cancer	2C25	Lung tissue	3.18E-12	5.84E-01	8.81E-01
Lupus erythematosus	4A40	Whole blood	8.53E-01	1.97E-01	2.21E-01
Major depressive disorder	6A70-6A7Z	Hippocampus	7.25E-01	-3.93E-02	-1.73E-01
Major depressive disorder	6A70-6A7Z	Whole blood	2.72E-01	-7.44E-02	-1.95E-01
Melanoma	2C30	Skin	1.58E-01	-3.61E-01	-4.08E-01
Multiple myeloma	2A83.1	Peripheral blood	7.76E-01	2.01E-01	4.06E-01
Multiple myeloma	2A83.1	Bone marrow	4.60E-05	1.33E+00	3.13E+00
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	1.67E-01	-1.07E-01	-3.47E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	2.07E-02	1.44E-01	4.07E-01
Myelofibrosis	2A20.2	Whole blood	3.97E-03	-3.37E-01	-9.87E-01
Myocardial infarction	BA41-BA50	Peripheral blood	1.37E-01	-3.98E-01	-3.59E-01
Myopathy	8C70.6	Muscle tissue	4.98E-02	-1.23E-01	-3.19E-01
Neonatal sepsis	KA60	Whole blood	2.86E-02	-3.64E-01	-5.21E-01
Neuroectodermal tumour	2A00.11	Brain stem tissue	3.82E-06	2.60E+00	3.09E+00
Non-alcoholic fatty liver disease	DB92	Liver tissue	1.44E-03	7.29E-01	1.91E+00
Obesity related type 2 diabetes	5A11	Omental adipose tissue	5.35E-01	1.04E-01	2.13E-01
Olive pollen allergy	CA08.00	Peripheral blood	4.38E-02	-4.06E-01	-1.17E+00
Oral cancer	2B6E	Oral tissue	1.64E-02	6.24E-01	6.67E-01
Osteoarthritis	FA00-FA0Z	Synovial tissue	8.00E-01	-2.39E-01	-2.44E-01
Osteoporosis	FB83.1	Bone marrow	6.23E-02	-3.36E-01	-5.50E-01
Ovarian cancer	2C73	Ovarian tissue	8.48E-01	-4.57E-02	-4.15E-02
Pancreatic cancer	2C10	Pancreas	1.04E-01	-1.07E-01	-1.32E-01
Parkinson's disease	8A00.0	Substantia nigra tissue	5.00E-01	-3.56E-01	-4.90E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	6.91E-01	1.52E-02	5.52E-02
Pituitary cancer	2D12	Pituitary tissue	4.04E-01	-1.83E-01	-2.86E-01
Pituitary gonadotrope tumour	2D12	Pituitary tissue	3.61E-01	4.73E-02	1.13E-01
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	8.52E-01	8.14E-02	4.61E-01
Polycythemia vera	2A20.4	Whole blood	1.61E-12	-4.85E-01	-1.38E+00
Pompe disease	5C51.3	Biceps muscle	8.00E-03	-4.88E-01	-2.40E+00
Preterm birth	KA21.4Z	Myometrium	2.35E-01	-1.18E+00	-1.81E+00
Prostate cancer	2C82	Prostate	1.79E-04	5.87E-01	7.53E-01
Psoriasis	EA90	Skin	5.69E-05	-1.37E-01	-3.09E-01
Rectal cancer	2B92	Rectal colon tissue	9.67E-08	-7.98E-01	-5.23E+00
Renal cancer	2C90-2C91	Kidney	4.58E-04	7.14E-01	1.03E+00
Retinoblastoma	2D02.2	Uvea	8.06E-01	3.71E-02	1.36E-01
Rheumatoid arthritis	FA20	Synovial tissue	4.54E-01	3.78E-01	4.49E-01
Rhinovirus infection	CA42.1	Nasal epithelium tissue	2.52E-01	-6.28E-02	-4.03E-01
Schizophrenia	6A20	Prefrontal cortex	9.81E-02	-2.63E-01	-5.22E-01
Schizophrenia	6A20	Superior temporal cortex	6.91E-02	1.92E-01	5.83E-01
Scleroderma	4A42.Z	Whole blood	9.75E-01	4.42E-03	1.88E-02
Seizure	8A60-8A6Z	Whole blood	2.30E-01	5.51E-01	6.81E-01
Sensitive skin	EK0Z	Skin	8.97E-01	1.06E-01	5.68E-01
Sepsis with septic shock	1G41	Whole blood	3.07E-14	-6.22E-01	-1.07E+00
Shwachman-Diamond syndrome	3A70.0	Bone marrow	1.32E-02	-7.18E-01	-1.61E+00
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	4.83E-02	-4.36E-01	-5.49E-01
Simpson golabi behmel syndrome	LD2C	Adipose tissue	8.09E-02	6.06E-01	1.61E+00
Sjogren's syndrome	4A43.2	Salivary gland tissue	3.57E-01	-2.42E-01	-1.39E+00
Skin cancer	2C30-2C3Z	Skin	5.27E-03	2.02E-01	2.83E-01
Thrombocythemia	3B63	Whole blood	1.30E-03	-3.35E-01	-9.93E-01
Thrombocytopenia	3B64	Whole blood	2.12E-01	-8.23E-01	-7.99E-01
Thyroid cancer	2D10	Thyroid	1.30E-12	2.15E-01	7.97E-01
Tibial muscular dystrophy	8C75	Muscle tissue	7.37E-01	-2.46E-01	-4.67E-01
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	1.05E-01	-4.30E-01	-5.40E+00
Type 2 diabetes	5A11	Liver tissue	4.25E-01	1.09E-01	6.71E-01
Ureter cancer	2C92	Urothelium	2.48E-01	1.02E-01	1.83E-01
Uterine cancer	2C78	Endometrium tissue	5.07E-04	3.26E-01	4.46E-01
Vitiligo	ED63.0	Skin	5.96E-01	1.83E-01	4.86E-01