Details of the Drug-Related molecule(s) Expression Atlas

General Information of DME (ID: DEVDR46)

• DME Name: Pyrrolidone-carboxylate peptidase (PGPI) DME Info
• Gene Name: PGPEP1

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	1.08E-22	3.01E-01	1.10E+00
Alopecia	ED70	Skin from scalp	1.49E-02	-4.71E-02	-1.98E-01
Alzheimer's disease	8A20	Entorhinal cortex	2.18E-04	1.67E-01	7.39E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	4.54E-02	2.20E-01	1.42E+00
Aortic stenosis	BB70	Calcified aortic valve	7.14E-01	-7.06E-03	-2.70E-02
Apnea	7A40	Hyperplastic tonsil	1.85E-01	2.51E-01	7.71E-01
Arthropathy	FA00-FA5Z	Peripheral blood	4.63E-01	4.30E-03	4.08E-02
Asthma	CA23	Nasal and bronchial airway	2.03E-02	6.35E-02	2.19E-01
Atopic dermatitis	EA80	Skin	1.61E-01	2.31E-02	1.31E-01
Autism	6A02	Whole blood	3.27E-01	-1.45E-01	-5.91E-01
Autoimmune uveitis	9A96	Peripheral monocyte	8.85E-01	-1.95E-01	-1.09E+00
Autosomal dominant monocytopenia	4B04	Whole blood	1.05E-03	7.97E-01	3.05E+00
Bacterial infection of gingival	1C1H	Gingival tissue	5.20E-27	4.89E-01	2.15E+00
Batten disease	5C56.1	Whole blood	8.88E-01	-6.78E-03	-4.41E-02
Behcet's disease	4A62	Peripheral blood	9.30E-02	-1.01E-01	-6.67E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	5.98E-01	5.85E-02	2.14E-01
Bladder cancer	2C94	Bladder tissue	7.04E-03	-3.64E-01	-1.61E+00
Breast cancer	2C60-2C6Z	Breast tissue	1.58E-08	-1.22E-01	-3.86E-01
Cardioembolic stroke	8B11.20	Whole blood	8.24E-01	5.32E-02	3.18E-01
Cervical cancer	2C77	Cervical tissue	3.94E-01	2.59E-02	8.11E-02
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	1.68E-01	5.81E-02	2.81E-01
Chronic hepatitis C	1E51.1	Whole blood	3.50E-01	-5.46E-02	-3.62E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	7.35E-01	-9.83E-03	-5.94E-02
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	9.68E-03	-6.56E-02	-2.61E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	8.96E-01	-6.16E-02	-2.71E-01
Colon cancer	2B90	Colon tissue	1.14E-36	-4.40E-01	-1.35E+00
Coronary artery disease	BA80-BA8Z	Peripheral blood	2.04E-01	1.08E-01	9.56E-01
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	6.60E-01	-1.57E-01	-3.31E-01
Endometriosis	GA10	Endometrium tissue	7.86E-01	1.74E-01	3.02E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	5.86E-02	-1.13E-01	-8.93E-01
Familial hypercholesterolemia	5C80.00	Whole blood	8.61E-02	-8.42E-02	-5.29E-01
Gastric cancer	2B72	Gastric tissue	1.36E-01	-4.51E-01	-1.48E+00
Glioblastopma	2A00.00	Nervous tissue	3.84E-04	1.19E-01	2.70E-01
Glioma	2A00.0Y-2A00.0Z	Brain stem tissue	7.45E-02	-2.66E-01	-2.81E+00
Glioma	2A00.0Y-2A00.0Z	White matter tissue	8.84E-02	-1.69E-01	-5.84E-01
Head and neck cancer	2D42	Head and neck tissue	7.73E-15	-5.68E-01	-1.23E+00
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	7.27E-01	1.47E-02	9.65E-02
Huntington's disease	8A01.10	Whole blood	2.32E-01	1.30E-01	9.72E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	2.88E-01	1.20E-01	4.99E-01
Immunodeficiency	4A00-4A20	Peripheral blood	7.65E-01	-4.19E-02	-4.38E-01
Influenza	1E30	Whole blood	5.94E-01	5.66E-02	2.81E+00
Interstitial cystitis	GC00.3	Bladder tissue	4.70E-03	-3.98E-01	-2.35E+00
Intracranial aneurysm	8B01.0	Intracranial artery	2.66E-02	3.47E-01	1.08E+00
Irritable bowel syndrome	DD91.0	Rectal colon tissue	2.15E-02	-1.29E-01	-5.00E-01
Ischemic stroke	8B11	Peripheral blood	2.85E-01	-4.16E-02	-2.99E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	3.90E-01	3.89E-02	1.81E-01
Lateral sclerosis	8B60.4	Skin	5.39E-01	8.23E-02	7.95E-01
Lateral sclerosis	8B60.4	Cervical spinal cord	8.10E-01	9.38E-02	2.61E-01
Liver cancer	2C12.0	Liver tissue	4.34E-02	-9.42E-02	-2.55E-01
Liver failure	DB99.7-DB99.8	Liver tissue	9.16E-01	4.90E-02	1.27E-01
Lung cancer	2C25	Lung tissue	2.99E-01	-1.98E-02	-9.30E-02
Lupus erythematosus	4A40	Whole blood	1.59E-01	-1.73E-02	-6.36E-02
Major depressive disorder	6A70-6A7Z	Hippocampus	3.61E-01	-1.19E-01	-4.45E-01
Major depressive disorder	6A70-6A7Z	Whole blood	9.02E-01	-1.53E-02	-7.71E-02
Melanoma	2C30	Skin	3.04E-01	1.92E-01	3.42E-01
Multiple myeloma	2A83.1	Peripheral blood	6.16E-01	2.10E-01	5.44E-01
Multiple myeloma	2A83.1	Bone marrow	1.08E-02	2.91E-01	1.24E+00
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	8.01E-01	-1.88E-02	-7.91E-02
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	1.62E-07	2.95E-01	1.17E+00
Myelofibrosis	2A20.2	Whole blood	1.88E-01	-4.67E-02	-7.18E-01
Myocardial infarction	BA41-BA50	Peripheral blood	2.29E-01	1.44E-02	5.05E-02
Myopathy	8C70.6	Muscle tissue	5.84E-01	-7.39E-02	-2.68E-01
Neonatal sepsis	KA60	Whole blood	2.44E-08	1.90E-01	9.54E-01
Neuroectodermal tumour	2A00.11	Brain stem tissue	6.05E-09	-1.32E+00	-5.45E+00
Non-alcoholic fatty liver disease	DB92	Liver tissue	1.56E-01	-1.73E-01	-4.76E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	9.89E-02	1.49E-01	4.73E-01
Olive pollen allergy	CA08.00	Peripheral blood	1.67E-01	1.15E-01	6.25E-01
Oral cancer	2B6E	Oral tissue	1.18E-04	-4.57E-01	-8.05E-01
Osteoarthritis	FA00-FA0Z	Synovial tissue	6.07E-01	8.21E-02	3.21E-01
Osteoporosis	FB83.1	Bone marrow	1.88E-01	1.16E-01	5.82E-01
Ovarian cancer	2C73	Ovarian tissue	1.23E-01	-4.92E-02	-1.62E-01
Pancreatic cancer	2C10	Pancreas	2.32E-02	-3.70E-01	-1.12E+00
Parkinson's disease	8A00.0	Substantia nigra tissue	4.37E-02	1.66E-01	8.17E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	8.38E-02	1.13E-01	7.97E-01
Pituitary cancer	2D12	Pituitary tissue	1.13E-05	-5.31E-01	-1.93E+00
Pituitary gonadotrope tumour	2D12	Pituitary tissue	1.47E-05	-5.72E-01	-2.45E+00
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	9.09E-01	3.23E-02	2.56E-01
Polycythemia vera	2A20.4	Whole blood	3.56E-01	2.40E-02	3.22E-01
Pompe disease	5C51.3	Biceps muscle	3.15E-01	1.52E-01	4.69E-01
Preterm birth	KA21.4Z	Myometrium	6.77E-02	8.41E-02	3.89E-01
Prostate cancer	2C82	Prostate	1.73E-06	2.45E-01	9.63E-01
Psoriasis	EA90	Skin	1.52E-04	-9.14E-02	-4.29E-01
Rectal cancer	2B92	Rectal colon tissue	1.12E-02	-3.61E-01	-1.93E+00
Renal cancer	2C90-2C91	Kidney	1.44E-02	-4.51E-01	-6.49E-01
Retinoblastoma	2D02.2	Uvea	6.66E-10	1.25E+00	5.39E+00
Rheumatoid arthritis	FA20	Synovial tissue	3.61E-02	5.34E-01	1.46E+00
Rhinovirus infection	CA42.1	Nasal epithelium tissue	8.89E-04	-9.27E-02	-5.95E-01
Schizophrenia	6A20	Prefrontal cortex	3.75E-01	7.97E-02	2.07E-01
Schizophrenia	6A20	Superior temporal cortex	9.01E-01	1.21E-02	8.08E-02
Scleroderma	4A42.Z	Whole blood	7.27E-02	7.65E-02	7.06E-01
Seizure	8A60-8A6Z	Whole blood	3.38E-01	-1.11E-01	-6.89E-01
Sensitive skin	EK0Z	Skin	4.40E-01	-1.30E-01	-1.02E+00
Sepsis with septic shock	1G41	Whole blood	2.66E-37	1.79E-01	1.15E+00
Shwachman-Diamond syndrome	3A70.0	Bone marrow	3.60E-01	1.45E-01	6.83E-01
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	9.24E-03	4.39E-01	1.52E+00
Simpson golabi behmel syndrome	LD2C	Adipose tissue	5.18E-01	8.72E-02	6.61E-01
Sjogren's syndrome	4A43.2	Salivary gland tissue	5.98E-02	-3.14E-01	-2.39E+00
Skin cancer	2C30-2C3Z	Skin	4.45E-49	6.11E-01	1.88E+00
Thrombocythemia	3B63	Whole blood	8.52E-01	-3.23E-02	-4.18E-01
Thrombocytopenia	3B64	Whole blood	7.06E-01	2.56E-01	2.35E-01
Thyroid cancer	2D10	Thyroid	2.08E-20	3.68E-01	1.92E+00
Tibial muscular dystrophy	8C75	Muscle tissue	7.10E-03	-3.85E-01	-1.06E+00
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	3.27E-02	7.02E-01	4.70E+00
Type 2 diabetes	5A11	Liver tissue	3.65E-01	-2.64E-01	-1.09E+00
Ureter cancer	2C92	Urothelium	4.11E-01	1.43E-02	9.77E-02
Uterine cancer	2C78	Endometrium tissue	7.42E-12	-2.71E-01	-6.22E-01
Vitiligo	ED63.0	Skin	6.07E-02	-2.51E-01	-1.19E+00