Details of the Drug-Related molecule(s) Expression Atlas

General Information of DME (ID: DEWJYTE)

• DME Name: Uridine 5'-monophosphate synthase (UMPS) DME Info
• Gene Name: UMPS

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	6.72E-09	-2.29E-01	-6.51E-01
Alopecia	ED70	Skin from scalp	4.45E-02	1.17E-01	5.16E-01
Alzheimer's disease	8A20	Entorhinal cortex	5.16E-04	-7.00E-02	-5.60E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	1.33E-01	1.69E-01	9.47E-01
Aortic stenosis	BB70	Calcified aortic valve	9.97E-01	-8.81E-02	-3.30E-01
Apnea	7A40	Hyperplastic tonsil	1.45E-01	-1.64E-01	-3.73E-01
Arthropathy	FA00-FA5Z	Peripheral blood	7.31E-02	-1.87E-01	-1.39E+00
Asthma	CA23	Nasal and bronchial airway	2.66E-02	1.29E-01	3.36E-01
Atopic dermatitis	EA80	Skin	5.65E-01	6.56E-02	2.87E-01
Autism	6A02	Whole blood	6.13E-01	3.79E-03	1.45E-02
Autoimmune uveitis	9A96	Peripheral monocyte	5.18E-01	9.14E-02	5.64E-01
Autosomal dominant monocytopenia	4B04	Whole blood	5.91E-01	-4.49E-02	-3.12E-01
Bacterial infection of gingival	1C1H	Gingival tissue	6.04E-11	-1.87E-01	-1.17E+00
Batten disease	5C56.1	Whole blood	9.77E-01	-5.77E-03	-3.40E-02
Behcet's disease	4A62	Peripheral blood	9.38E-01	-1.06E-01	-3.91E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	9.43E-01	4.28E-02	2.83E-01
Bladder cancer	2C94	Bladder tissue	1.57E-01	7.11E-02	5.32E-01
Breast cancer	2C60-2C6Z	Breast tissue	3.00E-10	8.49E-02	2.30E-01
Cardioembolic stroke	8B11.20	Whole blood	1.07E-05	-2.81E-01	-1.44E+00
Cervical cancer	2C77	Cervical tissue	2.87E-01	4.62E-02	1.95E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	3.80E-01	5.34E-02	9.95E-02
Chronic hepatitis C	1E51.1	Whole blood	1.00E-02	1.62E-01	1.32E+00
Chronic obstructive pulmonary disease	CA22	Lung tissue	1.36E-01	-3.19E-02	-2.13E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	5.80E-01	5.24E-02	2.54E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	6.03E-01	-6.63E-03	-6.49E-02
Colon cancer	2B90	Colon tissue	4.84E-33	3.15E-01	1.34E+00
Coronary artery disease	BA80-BA8Z	Peripheral blood	7.09E-02	1.77E-01	1.12E+00
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	3.98E-01	1.72E-01	4.68E-01
Endometriosis	GA10	Endometrium tissue	4.43E-01	-5.25E-02	-1.56E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	8.21E-01	2.30E-02	1.83E-01
Familial hypercholesterolemia	5C80.00	Whole blood	8.83E-03	1.70E-01	6.90E-01
Gastric cancer	2B72	Gastric tissue	5.24E-02	4.97E-01	1.81E+00
Glioblastopma	2A00.00	Nervous tissue	1.22E-171	6.81E-01	2.42E+00
Glioma	2A00.0Y-2A00.0Z	Brain stem tissue	4.25E-05	6.84E-01	1.05E+01
Glioma	2A00.0Y-2A00.0Z	White matter tissue	1.52E-03	5.59E-01	1.44E+00
Head and neck cancer	2D42	Head and neck tissue	1.09E-13	2.39E-01	1.07E+00
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	1.59E-01	-1.14E-01	-8.11E-01
Huntington's disease	8A01.10	Whole blood	2.09E-01	-1.38E-01	-8.75E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	7.72E-01	-2.42E-02	-1.25E-01
Immunodeficiency	4A00-4A20	Peripheral blood	4.05E-01	-1.59E-02	-1.11E-01
Influenza	1E30	Whole blood	1.64E-02	-7.56E-01	-4.17E+00
Interstitial cystitis	GC00.3	Bladder tissue	8.81E-02	-1.57E-01	-2.54E+00
Intracranial aneurysm	8B01.0	Intracranial artery	3.01E-02	1.45E-01	5.75E-01
Irritable bowel syndrome	DD91.0	Rectal colon tissue	6.64E-01	3.35E-03	1.58E-02
Ischemic stroke	8B11	Peripheral blood	6.28E-01	-1.44E-01	-3.86E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	9.38E-08	-1.94E-01	-6.74E-01
Lateral sclerosis	8B60.4	Skin	3.33E-01	6.47E-02	1.11E+00
Lateral sclerosis	8B60.4	Cervical spinal cord	4.34E-01	-1.47E-02	-8.66E-02
Liver cancer	2C12.0	Liver tissue	6.11E-01	-3.37E-02	-1.11E-01
Liver failure	DB99.7-DB99.8	Liver tissue	1.12E-02	-5.62E-01	-2.43E+00
Lung cancer	2C25	Lung tissue	3.64E-55	2.81E-01	1.59E+00
Lupus erythematosus	4A40	Whole blood	1.77E-01	5.13E-02	1.06E-01
Major depressive disorder	6A70-6A7Z	Hippocampus	4.99E-01	7.34E-02	4.74E-01
Major depressive disorder	6A70-6A7Z	Whole blood	5.23E-01	-2.37E-02	-1.07E-01
Melanoma	2C30	Skin	3.86E-01	-1.86E-01	-5.01E-01
Multiple myeloma	2A83.1	Peripheral blood	3.37E-01	-2.19E-01	-3.40E-01
Multiple myeloma	2A83.1	Bone marrow	7.24E-07	3.19E-01	3.69E+00
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	1.26E-01	-2.20E-01	-6.41E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	7.11E-03	1.75E-01	4.90E-01
Myelofibrosis	2A20.2	Whole blood	3.34E-02	-1.18E-01	-1.09E+00
Myocardial infarction	BA41-BA50	Peripheral blood	1.84E-06	-3.22E-01	-7.81E-01
Myopathy	8C70.6	Muscle tissue	8.16E-01	4.43E-02	2.24E-01
Neonatal sepsis	KA60	Whole blood	1.22E-15	-2.95E-01	-1.14E+00
Neuroectodermal tumour	2A00.11	Brain stem tissue	3.83E-10	1.27E+00	6.56E+00
Non-alcoholic fatty liver disease	DB92	Liver tissue	6.81E-02	4.23E-01	5.59E+00
Obesity related type 2 diabetes	5A11	Omental adipose tissue	6.11E-01	-2.66E-02	-1.19E-01
Olive pollen allergy	CA08.00	Peripheral blood	7.71E-01	7.01E-02	5.67E-01
Oral cancer	2B6E	Oral tissue	2.66E-03	3.49E-01	6.21E-01
Osteoarthritis	FA00-FA0Z	Synovial tissue	3.62E-01	1.68E-01	5.88E-01
Osteoporosis	FB83.1	Bone marrow	1.88E-01	-7.10E-02	-4.29E-01
Ovarian cancer	2C73	Ovarian tissue	4.28E-05	4.92E-01	2.77E+00
Pancreatic cancer	2C10	Pancreas	8.72E-01	-1.39E-02	-7.95E-02
Parkinson's disease	8A00.0	Substantia nigra tissue	1.71E-01	-9.53E-02	-4.42E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	9.61E-01	3.14E-02	1.70E-01
Pituitary cancer	2D12	Pituitary tissue	1.20E-09	7.38E-01	3.65E+00
Pituitary gonadotrope tumour	2D12	Pituitary tissue	2.70E-10	8.18E-01	5.48E+00
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	3.46E-01	-2.57E-02	-2.00E-01
Polycythemia vera	2A20.4	Whole blood	1.76E-11	-1.72E-01	-1.57E+00
Pompe disease	5C51.3	Biceps muscle	1.77E-02	-1.78E-01	-1.38E+00
Preterm birth	KA21.4Z	Myometrium	8.07E-01	-8.09E-02	-2.98E-01
Prostate cancer	2C82	Prostate	9.86E-08	5.52E-01	1.81E+00
Psoriasis	EA90	Skin	5.66E-30	4.24E-01	1.79E+00
Rectal cancer	2B92	Rectal colon tissue	1.94E-02	3.05E-01	1.45E+00
Renal cancer	2C90-2C91	Kidney	1.99E-02	2.27E-01	8.19E-01
Retinoblastoma	2D02.2	Uvea	2.70E-07	8.97E-01	3.86E+00
Rheumatoid arthritis	FA20	Synovial tissue	8.32E-01	-1.75E-01	-5.15E-01
Rhinovirus infection	CA42.1	Nasal epithelium tissue	8.27E-01	1.74E-02	1.38E-01
Schizophrenia	6A20	Prefrontal cortex	5.23E-01	2.11E-02	5.06E-02
Schizophrenia	6A20	Superior temporal cortex	1.00E+00	4.18E-03	4.49E-02
Scleroderma	4A42.Z	Whole blood	6.35E-02	-7.92E-02	-4.14E-01
Seizure	8A60-8A6Z	Whole blood	4.02E-01	2.35E-01	9.22E-01
Sensitive skin	EK0Z	Skin	5.82E-01	3.23E-02	3.33E-01
Sepsis with septic shock	1G41	Whole blood	3.24E-43	-3.26E-01	-1.39E+00
Shwachman-Diamond syndrome	3A70.0	Bone marrow	5.47E-01	1.90E-02	5.87E-02
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	8.56E-02	-8.12E-02	-5.11E-01
Simpson golabi behmel syndrome	LD2C	Adipose tissue	1.83E-01	-2.92E-01	-1.61E+00
Sjogren's syndrome	4A43.2	Salivary gland tissue	3.43E-01	1.68E-01	8.99E-01
Skin cancer	2C30-2C3Z	Skin	1.78E-19	2.68E-01	9.39E-01
Thrombocythemia	3B63	Whole blood	5.78E-05	-1.32E-01	-1.20E+00
Thrombocytopenia	3B64	Whole blood	1.19E-03	-3.96E-01	-1.46E+00
Thyroid cancer	2D10	Thyroid	4.31E-01	-4.77E-02	-2.60E-01
Tibial muscular dystrophy	8C75	Muscle tissue	2.25E-01	5.17E-02	2.53E-01
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	6.48E-01	6.75E-02	3.40E-01
Type 2 diabetes	5A11	Liver tissue	3.75E-01	1.48E-02	8.10E-02
Ureter cancer	2C92	Urothelium	6.11E-01	2.81E-02	2.18E-01
Uterine cancer	2C78	Endometrium tissue	3.02E-24	4.89E-01	1.45E+00
Vitiligo	ED63.0	Skin	9.38E-03	2.63E-01	1.50E+00