Details of the Drug-Related molecule(s) Expression Atlas

General Information of DME (ID: DEX8J7E)

• DME Name: Testicular 17-beta-hydroxysteroid dehydrogenase (HSD17B3) DME Info
• Gene Name: HSD17B3

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	8.84E-01	-2.75E-02	-1.14E-01
Alopecia	ED70	Skin from scalp	8.50E-01	8.33E-02	2.14E-01
Alzheimer's disease	8A20	Entorhinal cortex	1.31E-02	3.27E-01	4.98E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	5.61E-01	5.36E-02	3.25E-01
Aortic stenosis	BB70	Calcified aortic valve	5.18E-01	-5.72E-02	-8.88E-02
Apnea	7A40	Hyperplastic tonsil	2.46E-01	-1.71E-01	-3.08E-01
Arthropathy	FA00-FA5Z	Peripheral blood	1.66E-01	9.80E-02	4.40E-01
Asthma	CA23	Nasal and bronchial airway	2.17E-05	3.69E-01	3.38E-01
Atopic dermatitis	EA80	Skin	4.53E-01	-4.40E-02	-3.42E-01
Autism	6A02	Whole blood	5.72E-01	-3.64E-02	-1.35E-01
Autoimmune uveitis	9A96	Peripheral monocyte	9.66E-05	-3.13E-01	-2.24E+00
Autosomal dominant monocytopenia	4B04	Whole blood	2.77E-01	1.27E-01	8.41E-01
Bacterial infection of gingival	1C1H	Gingival tissue	2.40E-03	1.37E-01	4.27E-01
Batten disease	5C56.1	Whole blood	6.57E-01	1.03E-01	1.72E-01
Behcet's disease	4A62	Peripheral blood	5.46E-01	0.00E+00	0.00E+00
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	2.17E-01	-6.94E-02	-2.23E-01
Bladder cancer	2C94	Bladder tissue	5.71E-07	5.22E-01	3.14E+00
Breast cancer	2C60-2C6Z	Breast tissue	7.86E-01	-1.58E-03	-5.22E-03
Cardioembolic stroke	8B11.20	Whole blood	1.71E-01	-1.74E-01	-4.48E-01
Cervical cancer	2C77	Cervical tissue	3.36E-01	-9.86E-02	-3.27E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	7.95E-01	-4.52E-02	-1.26E-01
Chronic hepatitis C	1E51.1	Whole blood	1.41E-01	6.76E-02	4.40E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	1.72E-01	9.37E-02	3.64E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	2.23E-02	-2.85E-01	-5.61E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	1.88E-01	-2.03E-01	-3.43E-01
Colon cancer	2B90	Colon tissue	7.75E-01	-8.79E-02	-3.01E-01
Coronary artery disease	BA80-BA8Z	Peripheral blood	6.17E-01	1.02E-03	6.51E-03
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	6.83E-01	-2.80E-02	-1.06E-01
Endometriosis	GA10	Endometrium tissue	1.99E-01	6.70E-02	2.28E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	8.16E-01	-4.40E-02	-2.41E-01
Familial hypercholesterolemia	5C80.00	Whole blood	1.92E-02	-2.91E-01	-1.02E+00
Gastric cancer	2B72	Gastric tissue	5.18E-01	2.10E-01	7.47E-01
Glioblastopma	2A00.00	Nervous tissue	2.56E-02	-1.51E-01	-2.07E-01
Glioma	2A00.0Y-2A00.0Z	Brain stem tissue	5.45E-01	-1.05E+00	-5.72E-01
Glioma	2A00.0Y-2A00.0Z	White matter tissue	7.10E-03	-9.42E-01	-1.40E+00
Head and neck cancer	2D42	Head and neck tissue	1.98E-08	-3.05E-01	-3.08E-01
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	5.95E-01	-6.88E-02	-9.55E-02
Huntington's disease	8A01.10	Whole blood	1.45E-01	6.61E-03	2.87E-02
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	2.03E-01	-1.31E-01	-5.44E-01
Immunodeficiency	4A00-4A20	Peripheral blood	7.99E-01	7.00E-02	1.06E+00
Influenza	1E30	Whole blood	9.98E-01	1.78E-01	2.59E+00
Interstitial cystitis	GC00.3	Bladder tissue	1.60E-01	1.07E-01	1.03E+00
Intracranial aneurysm	8B01.0	Intracranial artery	2.07E-03	-4.03E-01	-1.16E+00
Irritable bowel syndrome	DD91.0	Rectal colon tissue	1.92E-01	-1.04E-01	-1.99E-01
Ischemic stroke	8B11	Peripheral blood	4.28E-02	1.08E-01	4.77E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	1.87E-01	-9.37E-02	-2.46E-01
Lateral sclerosis	8B60.4	Skin	6.15E-01	4.98E-02	3.91E-01
Lateral sclerosis	8B60.4	Cervical spinal cord	6.29E-01	-1.80E-01	-3.68E-01
Liver cancer	2C12.0	Liver tissue	6.85E-02	9.78E-02	2.07E-01
Liver failure	DB99.7-DB99.8	Liver tissue	1.40E-04	-6.87E-01	-2.32E+00
Lung cancer	2C25	Lung tissue	5.91E-08	-5.47E-03	-2.32E-02
Lupus erythematosus	4A40	Whole blood	1.15E-01	-6.12E-02	-1.33E-01
Major depressive disorder	6A70-6A7Z	Hippocampus	8.11E-01	1.69E-02	5.33E-02
Major depressive disorder	6A70-6A7Z	Whole blood	3.68E-01	1.35E-02	3.95E-02
Melanoma	2C30	Skin	4.96E-01	1.75E-02	2.34E-02
Multiple myeloma	2A83.1	Peripheral blood	4.51E-01	1.18E-02	5.62E-02
Multiple myeloma	2A83.1	Bone marrow	6.13E-01	-1.66E-01	-8.01E-01
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	3.46E-01	4.07E-01	1.16E+00
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	8.05E-01	1.82E-03	9.37E-03
Myelofibrosis	2A20.2	Whole blood	4.79E-01	-8.25E-02	-5.41E-01
Myocardial infarction	BA41-BA50	Peripheral blood	7.77E-01	-3.71E-02	-5.93E-02
Myopathy	8C70.6	Muscle tissue	8.43E-01	-4.30E-02	-2.54E-01
Neonatal sepsis	KA60	Whole blood	3.77E-01	-3.78E-02	-1.36E-01
Neuroectodermal tumour	2A00.11	Brain stem tissue	1.47E-05	-1.12E+00	-2.98E+00
Non-alcoholic fatty liver disease	DB92	Liver tissue	4.77E-01	1.38E-01	6.24E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	5.31E-02	1.13E-01	1.01E+00
Olive pollen allergy	CA08.00	Peripheral blood	4.75E-01	-1.56E-01	-4.42E-01
Oral cancer	2B6E	Oral tissue	4.83E-01	3.87E-02	8.34E-02
Osteoarthritis	FA00-FA0Z	Synovial tissue	5.78E-01	-2.52E-03	-1.38E-02
Osteoporosis	FB83.1	Bone marrow	4.58E-03	3.60E-01	2.08E+00
Ovarian cancer	2C73	Ovarian tissue	7.75E-02	-5.63E-02	-1.82E-01
Pancreatic cancer	2C10	Pancreas	4.28E-01	-1.09E-01	-1.83E-01
Parkinson's disease	8A00.0	Substantia nigra tissue	3.21E-01	-2.64E-01	-6.16E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	5.38E-01	5.59E-02	3.25E-01
Pituitary cancer	2D12	Pituitary tissue	4.77E-03	-2.04E-01	-5.71E-01
Pituitary gonadotrope tumour	2D12	Pituitary tissue	1.78E-02	-2.01E-01	-5.36E-01
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	5.22E-01	1.09E-01	5.00E-01
Polycythemia vera	2A20.4	Whole blood	1.30E-01	-6.51E-02	-4.20E-01
Pompe disease	5C51.3	Biceps muscle	6.99E-03	5.87E-01	1.97E+00
Preterm birth	KA21.4Z	Myometrium	6.25E-01	1.20E-02	1.74E-01
Prostate cancer	2C82	Prostate	3.54E-02	2.20E-01	3.98E-01
Psoriasis	EA90	Skin	2.59E-01	7.23E-03	2.40E-02
Rectal cancer	2B92	Rectal colon tissue	8.61E-01	-1.54E-01	-3.49E-01
Renal cancer	2C90-2C91	Kidney	2.56E-02	1.33E-01	4.05E-01
Retinoblastoma	2D02.2	Uvea	2.57E-01	-7.97E-03	-2.57E-02
Rheumatoid arthritis	FA20	Synovial tissue	6.10E-01	-2.01E-01	-4.53E-01
Rhinovirus infection	CA42.1	Nasal epithelium tissue	4.61E-01	7.05E-03	2.24E-02
Schizophrenia	6A20	Prefrontal cortex	9.91E-02	-9.25E-03	-2.52E-02
Schizophrenia	6A20	Superior temporal cortex	2.18E-02	-2.09E-01	-6.15E-01
Scleroderma	4A42.Z	Whole blood	3.65E-01	1.01E-01	2.63E-01
Seizure	8A60-8A6Z	Whole blood	8.25E-01	5.11E-02	2.67E-01
Sensitive skin	EK0Z	Skin	3.31E-01	3.00E-02	1.88E-01
Sepsis with septic shock	1G41	Whole blood	3.39E-01	6.11E-03	2.15E-02
Shwachman-Diamond syndrome	3A70.0	Bone marrow	1.42E-01	4.54E-01	1.16E+00
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	1.55E-02	-1.05E+00	-9.12E-01
Simpson golabi behmel syndrome	LD2C	Adipose tissue	7.22E-01	4.39E-02	3.71E-01
Sjogren's syndrome	4A43.2	Salivary gland tissue	4.72E-01	-1.31E-01	-3.58E-01
Skin cancer	2C30-2C3Z	Skin	7.54E-04	8.39E-02	2.00E-01
Thrombocythemia	3B63	Whole blood	5.17E-01	5.64E-02	3.75E-01
Thrombocytopenia	3B64	Whole blood	9.76E-01	1.21E-01	3.38E-01
Thyroid cancer	2D10	Thyroid	3.13E-31	-7.92E-01	-1.96E+00
Tibial muscular dystrophy	8C75	Muscle tissue	5.51E-03	2.12E-01	1.08E+00
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	1.41E-01	4.95E-01	1.14E+00
Type 2 diabetes	5A11	Liver tissue	5.79E-01	-9.78E-02	-1.66E-01
Ureter cancer	2C92	Urothelium	1.76E-01	-1.55E-01	-6.30E-01
Uterine cancer	2C78	Endometrium tissue	2.37E-03	2.63E-02	7.00E-02
Vitiligo	ED63.0	Skin	2.06E-01	1.62E-01	8.47E-01