Details of the Drug-Related molecule(s) Expression Atlas

General Information of DME (ID: DEXI4UQ)

• DME Name: Aldehyde dehydrogenase 5 (ALDHX) DME Info
• Gene Name: ALDH1B1

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	4.05E-14	1.86E-01	9.44E-01
Alopecia	ED70	Skin from scalp	8.22E-01	-3.29E-02	-1.65E-01
Alzheimer's disease	8A20	Entorhinal cortex	2.88E-05	-1.12E-01	-5.57E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	1.25E-01	2.07E-01	9.32E-01
Aortic stenosis	BB70	Calcified aortic valve	6.06E-01	8.10E-02	1.46E-01
Apnea	7A40	Hyperplastic tonsil	5.34E-01	1.76E-02	1.14E-01
Arthropathy	FA00-FA5Z	Peripheral blood	5.16E-01	3.21E-02	2.79E-01
Asthma	CA23	Nasal and bronchial airway	5.65E-02	-1.39E-01	-1.25E-01
Atopic dermatitis	EA80	Skin	5.46E-03	-1.69E-01	-8.30E-01
Autism	6A02	Whole blood	2.73E-01	-4.36E-02	-2.09E-01
Autoimmune uveitis	9A96	Peripheral monocyte	3.64E-05	-4.73E-01	-2.22E+00
Autosomal dominant monocytopenia	4B04	Whole blood	1.49E-01	-4.43E-02	-3.32E-01
Bacterial infection of gingival	1C1H	Gingival tissue	3.59E-03	1.31E-01	5.68E-01
Batten disease	5C56.1	Whole blood	8.13E-01	-1.20E-02	-1.92E-01
Behcet's disease	4A62	Peripheral blood	7.82E-01	-3.64E-02	-1.45E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	4.42E-01	-5.38E-02	-3.28E-01
Bladder cancer	2C94	Bladder tissue	8.95E-01	1.39E-01	1.86E-01
Breast cancer	2C60-2C6Z	Breast tissue	1.04E-23	2.60E-01	7.61E-01
Cardioembolic stroke	8B11.20	Whole blood	9.35E-01	-7.84E-03	-3.56E-02
Cervical cancer	2C77	Cervical tissue	1.58E-03	9.30E-02	4.76E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	6.80E-01	-1.91E-02	-1.27E-01
Chronic hepatitis C	1E51.1	Whole blood	6.40E-01	-1.04E-01	-7.41E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	9.11E-01	2.81E-02	9.61E-02
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	9.22E-01	-2.66E-02	-1.47E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	5.50E-01	-8.79E-02	-1.27E+00
Colon cancer	2B90	Colon tissue	4.89E-18	3.02E-01	7.81E-01
Coronary artery disease	BA80-BA8Z	Peripheral blood	5.27E-01	1.26E-02	1.29E-01
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	7.33E-01	5.98E-02	2.05E-01
Endometriosis	GA10	Endometrium tissue	2.56E-01	6.51E-03	2.49E-02
Familial hypercholesterolemia	5C80.00	Peripheral blood	5.45E-01	-1.95E-02	-1.79E-01
Familial hypercholesterolemia	5C80.00	Whole blood	5.46E-03	-9.77E-02	-5.68E-01
Gastric cancer	2B72	Gastric tissue	1.61E-01	1.01E+00	1.48E+00
Glioblastopma	2A00.00	Nervous tissue	4.11E-08	8.00E-02	2.92E-01
Glioma	2A00.0Y-2A00.0Z	Brain stem tissue	2.83E-01	1.19E-01	8.67E-01
Glioma	2A00.0Y-2A00.0Z	White matter tissue	9.01E-05	-3.76E-01	-1.68E+00
Head and neck cancer	2D42	Head and neck tissue	5.34E-13	2.06E-01	1.12E+00
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	1.86E-01	-7.01E-02	-4.02E-01
Huntington's disease	8A01.10	Whole blood	3.51E-01	5.01E-02	2.89E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	8.78E-02	1.98E-01	9.32E-01
Immunodeficiency	4A00-4A20	Peripheral blood	5.80E-01	7.31E-02	1.10E+00
Influenza	1E30	Whole blood	3.41E-02	-3.79E-01	-2.24E+00
Interstitial cystitis	GC00.3	Bladder tissue	2.00E-01	4.32E-01	1.20E+00
Intracranial aneurysm	8B01.0	Intracranial artery	2.97E-05	-1.34E+00	-1.57E+00
Irritable bowel syndrome	DD91.0	Rectal colon tissue	9.52E-01	1.46E-02	7.32E-02
Ischemic stroke	8B11	Peripheral blood	4.52E-01	-2.35E-02	-1.54E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	6.45E-01	-1.02E-02	-4.12E-02
Lateral sclerosis	8B60.4	Skin	6.89E-01	-2.20E-01	-3.40E-01
Lateral sclerosis	8B60.4	Cervical spinal cord	1.60E-01	1.24E+00	1.59E+00
Liver cancer	2C12.0	Liver tissue	9.97E-07	-1.21E+00	-1.31E+00
Liver failure	DB99.7-DB99.8	Liver tissue	1.15E-03	-9.89E-01	-1.90E+00
Lung cancer	2C25	Lung tissue	2.23E-10	1.78E-01	5.37E-01
Lupus erythematosus	4A40	Whole blood	1.45E-01	5.63E-02	1.03E-01
Major depressive disorder	6A70-6A7Z	Hippocampus	8.76E-01	-3.72E-02	-2.20E-01
Major depressive disorder	6A70-6A7Z	Whole blood	4.64E-01	1.37E-02	9.22E-02
Melanoma	2C30	Skin	2.85E-01	-4.00E-01	-5.14E-01
Multiple myeloma	2A83.1	Peripheral blood	4.38E-01	-1.60E-01	-4.90E-01
Multiple myeloma	2A83.1	Bone marrow	1.67E-01	7.91E-02	3.96E-01
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	7.13E-01	3.97E-02	1.53E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	3.33E-03	5.40E-02	2.78E-01
Myelofibrosis	2A20.2	Whole blood	5.43E-01	-9.21E-02	-8.65E-01
Myocardial infarction	BA41-BA50	Peripheral blood	3.74E-01	-1.93E-01	-2.41E-01
Myopathy	8C70.6	Muscle tissue	6.78E-04	6.79E-01	1.62E+00
Neonatal sepsis	KA60	Whole blood	3.58E-02	-8.44E-02	-3.90E-01
Neuroectodermal tumour	2A00.11	Brain stem tissue	2.84E-05	4.83E-01	2.22E+00
Non-alcoholic fatty liver disease	DB92	Liver tissue	8.73E-02	3.20E-01	1.40E+00
Obesity related type 2 diabetes	5A11	Omental adipose tissue	6.62E-01	-2.94E-02	-1.45E-01
Olive pollen allergy	CA08.00	Peripheral blood	8.38E-01	-2.39E-02	-1.12E-01
Oral cancer	2B6E	Oral tissue	1.63E-01	-5.00E-02	-1.64E-01
Osteoarthritis	FA00-FA0Z	Synovial tissue	6.85E-01	-1.73E-01	-3.78E-01
Osteoporosis	FB83.1	Bone marrow	4.78E-01	5.78E-01	4.72E-01
Ovarian cancer	2C73	Ovarian tissue	6.94E-01	6.13E-02	1.35E-01
Pancreatic cancer	2C10	Pancreas	1.15E-03	3.20E-01	7.37E-01
Parkinson's disease	8A00.0	Substantia nigra tissue	9.50E-02	-1.31E-01	-7.59E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	3.01E-03	-1.25E-01	-9.47E-01
Pituitary cancer	2D12	Pituitary tissue	9.90E-05	4.20E-01	1.72E+00
Pituitary gonadotrope tumour	2D12	Pituitary tissue	2.52E-02	2.23E-01	9.17E-01
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	4.77E-01	8.99E-02	4.40E-01
Polycythemia vera	2A20.4	Whole blood	1.76E-01	-5.05E-02	-4.85E-01
Pompe disease	5C51.3	Biceps muscle	2.96E-06	2.39E+00	1.00E+01
Preterm birth	KA21.4Z	Myometrium	2.45E-01	8.01E-01	1.25E+00
Prostate cancer	2C82	Prostate	7.00E-05	1.24E+00	1.15E+00
Psoriasis	EA90	Skin	1.47E-03	1.03E-01	2.32E-01
Rectal cancer	2B92	Rectal colon tissue	1.90E-02	3.80E-01	1.54E+00
Renal cancer	2C90-2C91	Kidney	1.30E-01	-5.53E-01	-8.49E-01
Retinoblastoma	2D02.2	Uvea	4.01E-07	1.96E+00	1.53E+01
Rheumatoid arthritis	FA20	Synovial tissue	5.33E-03	2.81E-01	1.17E+00
Rhinovirus infection	CA42.1	Nasal epithelium tissue	5.96E-01	-3.31E-03	-2.52E-02
Schizophrenia	6A20	Prefrontal cortex	7.97E-01	-6.93E-03	-3.55E-02
Schizophrenia	6A20	Superior temporal cortex	6.18E-01	-1.62E-02	-1.50E-01
Scleroderma	4A42.Z	Whole blood	4.97E-01	6.98E-02	4.70E-01
Seizure	8A60-8A6Z	Whole blood	5.12E-01	-2.08E-03	-1.27E-02
Sensitive skin	EK0Z	Skin	5.98E-01	2.61E-02	8.41E-02
Sepsis with septic shock	1G41	Whole blood	7.91E-02	-2.78E-02	-1.49E-01
Shwachman-Diamond syndrome	3A70.0	Bone marrow	1.92E-01	1.58E-01	9.08E-01
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	8.90E-01	3.05E-02	1.30E-01
Simpson golabi behmel syndrome	LD2C	Adipose tissue	6.67E-01	5.26E-03	2.89E-02
Sjogren's syndrome	4A43.2	Salivary gland tissue	1.89E-01	-1.51E-01	-6.68E-01
Skin cancer	2C30-2C3Z	Skin	1.84E-16	5.01E-01	8.19E-01
Thrombocythemia	3B63	Whole blood	1.39E-01	-1.35E-01	-1.27E+00
Thrombocytopenia	3B64	Whole blood	8.31E-01	-1.57E-02	-6.19E-02
Thyroid cancer	2D10	Thyroid	9.12E-25	-6.05E-01	-1.68E+00
Tibial muscular dystrophy	8C75	Muscle tissue	8.40E-01	1.83E-02	4.32E-02
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	3.94E-01	3.92E-02	4.35E-01
Type 2 diabetes	5A11	Liver tissue	1.89E-01	3.11E-01	1.03E+00
Ureter cancer	2C92	Urothelium	9.82E-02	4.10E-03	3.43E-02
Uterine cancer	2C78	Endometrium tissue	3.30E-01	-4.96E-02	-8.78E-02
Vitiligo	ED63.0	Skin	7.65E-01	3.37E-02	1.38E-01