Details of the Drug-Related molecule(s) Expression Atlas

General Information of DME (ID: DEXPVUN)

• DME Name: Short-chain dehydrogenase/reductase retSDR1 (DHRS3) DME Info
• Gene Name: DHRS3

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	3.69E-08	-5.29E-01	-1.08E+00
Alopecia	ED70	Skin from scalp	1.76E-01	7.76E-02	3.72E-01
Alzheimer's disease	8A20	Entorhinal cortex	1.45E-06	2.53E-01	4.76E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	1.92E-01	-1.67E-01	-9.90E-01
Aortic stenosis	BB70	Calcified aortic valve	7.71E-02	-1.30E-01	-3.97E-01
Apnea	7A40	Hyperplastic tonsil	9.19E-01	7.43E-02	2.47E-01
Arthropathy	FA00-FA5Z	Peripheral blood	4.48E-02	-3.35E-01	-1.09E+00
Asthma	CA23	Nasal and bronchial airway	5.18E-06	2.57E-01	3.30E-01
Atopic dermatitis	EA80	Skin	3.95E-01	-2.77E-02	-1.41E-01
Autism	6A02	Whole blood	9.04E-01	5.57E-02	1.62E-01
Autoimmune uveitis	9A96	Peripheral monocyte	6.89E-01	-5.50E-01	-1.09E+00
Autosomal dominant monocytopenia	4B04	Whole blood	6.21E-01	-1.16E-01	-3.74E-01
Bacterial infection of gingival	1C1H	Gingival tissue	9.94E-01	5.14E-02	1.41E-01
Batten disease	5C56.1	Whole blood	8.94E-01	8.29E-02	3.14E-01
Behcet's disease	4A62	Peripheral blood	1.08E-01	-1.22E-01	-3.79E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	4.23E-01	1.56E-01	4.94E-01
Bladder cancer	2C94	Bladder tissue	1.53E-03	-6.26E-01	-2.22E+00
Breast cancer	2C60-2C6Z	Breast tissue	2.35E-67	-1.13E+00	-1.31E+00
Cardioembolic stroke	8B11.20	Whole blood	2.21E-10	-7.33E-01	-2.55E+00
Cervical cancer	2C77	Cervical tissue	8.40E-01	1.34E-01	2.13E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	9.18E-01	-5.20E-02	-5.19E-02
Chronic hepatitis C	1E51.1	Whole blood	1.56E-01	-2.65E-01	-1.11E+00
Chronic obstructive pulmonary disease	CA22	Lung tissue	8.83E-02	-2.03E-01	-5.63E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	1.06E-01	1.67E-01	4.50E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	4.36E-03	-3.94E-01	-1.19E+00
Colon cancer	2B90	Colon tissue	5.35E-19	-2.70E-01	-7.98E-01
Coronary artery disease	BA80-BA8Z	Peripheral blood	5.37E-02	6.02E-01	1.64E+00
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	1.03E-01	1.35E-01	4.28E-01
Endometriosis	GA10	Endometrium tissue	7.33E-05	7.86E-01	1.08E+00
Familial hypercholesterolemia	5C80.00	Peripheral blood	1.42E-03	3.70E-01	1.21E+00
Familial hypercholesterolemia	5C80.00	Whole blood	3.91E-01	-8.20E-02	-2.16E-01
Gastric cancer	2B72	Gastric tissue	8.70E-01	-1.81E-01	-2.77E-01
Glioblastopma	2A00.00	Nervous tissue	5.85E-07	3.23E-01	4.88E-01
Glioma	2A00.0Y-2A00.0Z	Brain stem tissue	8.63E-01	5.75E-02	1.44E-01
Glioma	2A00.0Y-2A00.0Z	White matter tissue	8.33E-01	-2.72E-01	-1.81E-01
Head and neck cancer	2D42	Head and neck tissue	3.98E-21	-8.30E-01	-1.02E+00
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	4.18E-01	4.70E-02	1.44E-01
Huntington's disease	8A01.10	Whole blood	4.65E-01	2.46E-01	6.05E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	1.05E-01	2.15E-01	5.13E-01
Immunodeficiency	4A00-4A20	Peripheral blood	2.27E-04	-5.16E-01	-2.65E+00
Influenza	1E30	Whole blood	1.13E-01	1.31E-01	7.67E-01
Interstitial cystitis	GC00.3	Bladder tissue	1.17E-04	-9.55E-01	-6.14E+00
Intracranial aneurysm	8B01.0	Intracranial artery	1.54E-02	9.85E-01	1.77E+00
Irritable bowel syndrome	DD91.0	Rectal colon tissue	1.75E-01	-3.33E-01	-6.76E-01
Ischemic stroke	8B11	Peripheral blood	8.49E-01	-7.27E-02	-2.23E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	3.18E-09	-2.67E-01	-8.04E-01
Lateral sclerosis	8B60.4	Skin	2.86E-01	-1.31E-01	-1.64E-01
Lateral sclerosis	8B60.4	Cervical spinal cord	6.18E-01	1.03E-03	9.21E-04
Liver cancer	2C12.0	Liver tissue	1.41E-06	-3.81E-01	-9.73E-01
Liver failure	DB99.7-DB99.8	Liver tissue	3.38E-04	-1.02E+00	-2.52E+00
Lung cancer	2C25	Lung tissue	9.13E-22	-4.12E-01	-1.16E+00
Lupus erythematosus	4A40	Whole blood	1.14E-09	-4.62E-01	-5.58E-01
Major depressive disorder	6A70-6A7Z	Hippocampus	5.69E-02	-1.06E-01	-3.48E-01
Major depressive disorder	6A70-6A7Z	Whole blood	1.89E-01	-1.10E-01	-2.16E-01
Melanoma	2C30	Skin	1.53E-02	-7.49E-01	-8.32E-01
Multiple myeloma	2A83.1	Peripheral blood	9.05E-01	2.84E-02	1.49E-01
Multiple myeloma	2A83.1	Bone marrow	2.60E-02	-4.68E-01	-7.99E-01
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	2.16E-01	1.93E-01	5.51E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	2.46E-01	2.75E-01	4.67E-01
Myelofibrosis	2A20.2	Whole blood	3.39E-02	-4.63E-01	-2.02E+00
Myocardial infarction	BA41-BA50	Peripheral blood	8.68E-02	-3.99E-01	-4.87E-01
Myopathy	8C70.6	Muscle tissue	4.42E-01	-1.31E-02	-4.46E-02
Neonatal sepsis	KA60	Whole blood	1.75E-39	-1.07E+00	-2.79E+00
Neuroectodermal tumour	2A00.11	Brain stem tissue	3.50E-05	-9.11E-01	-2.21E+00
Non-alcoholic fatty liver disease	DB92	Liver tissue	2.62E-01	-4.39E-02	-2.39E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	4.33E-03	3.58E-01	2.72E+00
Olive pollen allergy	CA08.00	Peripheral blood	9.09E-01	-4.33E-01	-3.33E-01
Oral cancer	2B6E	Oral tissue	2.86E-04	-4.92E-01	-1.05E+00
Osteoarthritis	FA00-FA0Z	Synovial tissue	5.56E-01	4.84E-01	5.45E-01
Osteoporosis	FB83.1	Bone marrow	5.41E-01	-2.59E-01	-5.24E-01
Ovarian cancer	2C73	Ovarian tissue	8.76E-01	1.07E-01	1.72E-01
Pancreatic cancer	2C10	Pancreas	8.45E-02	2.84E-01	5.45E-01
Parkinson's disease	8A00.0	Substantia nigra tissue	4.51E-01	1.82E-01	3.88E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	2.43E-03	-1.48E-01	-6.09E-01
Pituitary cancer	2D12	Pituitary tissue	2.54E-09	-1.51E+00	-4.05E+00
Pituitary gonadotrope tumour	2D12	Pituitary tissue	7.70E-10	-1.80E+00	-4.89E+00
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	2.17E-01	-7.10E-02	-3.52E-01
Polycythemia vera	2A20.4	Whole blood	4.21E-13	-3.36E-01	-1.34E+00
Pompe disease	5C51.3	Biceps muscle	8.79E-01	-8.08E-02	-4.56E-01
Preterm birth	KA21.4Z	Myometrium	2.58E-02	-7.52E-01	-1.96E+00
Prostate cancer	2C82	Prostate	6.83E-04	-1.25E-01	-3.38E-01
Psoriasis	EA90	Skin	3.60E-13	-3.07E-01	-9.97E-01
Rectal cancer	2B92	Rectal colon tissue	3.82E-03	-4.41E-01	-1.50E+00
Renal cancer	2C90-2C91	Kidney	5.85E-01	1.47E-01	5.62E-01
Retinoblastoma	2D02.2	Uvea	1.57E-01	-4.62E-01	-1.01E+00
Rheumatoid arthritis	FA20	Synovial tissue	1.27E-05	9.65E-01	3.64E+00
Rhinovirus infection	CA42.1	Nasal epithelium tissue	1.84E-01	-7.56E-02	-3.64E-01
Schizophrenia	6A20	Prefrontal cortex	1.97E-02	2.56E-01	5.62E-01
Schizophrenia	6A20	Superior temporal cortex	5.88E-01	3.49E-02	9.69E-02
Scleroderma	4A42.Z	Whole blood	3.54E-06	-5.64E-01	-2.94E+00
Seizure	8A60-8A6Z	Whole blood	4.78E-01	-1.10E-02	-2.37E-02
Sensitive skin	EK0Z	Skin	7.77E-01	-6.76E-02	-2.83E-01
Sepsis with septic shock	1G41	Whole blood	4.11E-89	-1.01E+00	-2.98E+00
Shwachman-Diamond syndrome	3A70.0	Bone marrow	6.20E-01	8.30E-02	2.87E-01
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	8.20E-01	1.67E-01	2.23E-01
Simpson golabi behmel syndrome	LD2C	Adipose tissue	1.94E-01	5.95E-01	1.24E+00
Sjogren's syndrome	4A43.2	Salivary gland tissue	8.62E-02	4.93E-02	4.24E-01
Skin cancer	2C30-2C3Z	Skin	8.06E-66	-1.02E+00	-2.58E+00
Thrombocythemia	3B63	Whole blood	1.31E-04	-2.06E-01	-8.64E-01
Thrombocytopenia	3B64	Whole blood	6.52E-01	7.85E-01	5.90E-01
Thyroid cancer	2D10	Thyroid	9.05E-06	5.39E-01	1.60E+00
Tibial muscular dystrophy	8C75	Muscle tissue	6.82E-03	-3.24E-01	-8.13E-01
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	1.98E-02	9.22E-01	1.89E+00
Type 2 diabetes	5A11	Liver tissue	7.49E-01	3.08E-02	1.65E-01
Ureter cancer	2C92	Urothelium	8.79E-01	-3.41E-02	-6.89E-02
Uterine cancer	2C78	Endometrium tissue	1.22E-03	5.18E-03	5.06E-03
Vitiligo	ED63.0	Skin	2.29E-01	3.81E-02	1.78E-01