Details of the Drug-Related molecule(s) Expression Atlas

General Information of DME (ID: DEZGVDW)

• DME Name: Steroid 5-alpha-reductase 3 (SRD5A3) DME Info
• Gene Name: SRD5A3

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	4.27E-33	4.10E-01	1.60E+00
Alopecia	ED70	Skin from scalp	3.82E-01	1.75E-01	2.11E-01
Alzheimer's disease	8A20	Entorhinal cortex	1.74E-02	-2.04E-01	-5.23E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	3.48E-01	1.87E-01	5.03E-01
Aortic stenosis	BB70	Calcified aortic valve	4.53E-01	-2.58E-01	-6.41E-01
Apnea	7A40	Hyperplastic tonsil	2.10E-01	-7.89E-01	-1.70E+00
Arthropathy	FA00-FA5Z	Peripheral blood	6.82E-02	-1.57E-01	-4.98E-01
Asthma	CA23	Nasal and bronchial airway	3.75E-05	2.38E-01	3.41E-01
Atopic dermatitis	EA80	Skin	1.41E-01	1.10E-02	2.92E-02
Autism	6A02	Whole blood	6.89E-01	6.88E-04	4.01E-03
Autoimmune uveitis	9A96	Peripheral monocyte	4.62E-01	-8.32E-03	-3.72E-02
Autosomal dominant monocytopenia	4B04	Whole blood	7.22E-01	3.57E-02	2.63E-01
Bacterial infection of gingival	1C1H	Gingival tissue	3.45E-09	-4.56E-01	-8.34E-01
Batten disease	5C56.1	Whole blood	9.86E-01	4.30E-02	1.56E-01
Behcet's disease	4A62	Peripheral blood	9.45E-01	1.77E-01	2.54E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	3.11E-01	1.16E-01	4.87E-01
Bladder cancer	2C94	Bladder tissue	9.60E-01	1.80E-01	2.61E-01
Breast cancer	2C60-2C6Z	Breast tissue	9.21E-63	7.17E-01	1.32E+00
Cardioembolic stroke	8B11.20	Whole blood	8.20E-01	1.59E-01	2.37E-01
Cervical cancer	2C77	Cervical tissue	2.62E-01	6.01E-02	5.02E-02
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	3.79E-01	-7.92E-02	-1.65E-01
Chronic hepatitis C	1E51.1	Whole blood	6.15E-01	-2.51E-02	-1.33E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	5.20E-01	-3.99E-02	-1.11E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	1.71E-01	9.62E-02	1.95E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	1.52E-02	1.78E+00	2.56E+00
Colon cancer	2B90	Colon tissue	1.15E-17	3.92E-01	7.37E-01
Coronary artery disease	BA80-BA8Z	Peripheral blood	9.24E-02	2.51E-01	1.01E+00
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	2.47E-01	-3.22E-02	-1.79E-01
Endometriosis	GA10	Endometrium tissue	6.20E-02	3.80E-01	6.30E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	5.15E-01	-1.59E-01	-4.06E-01
Familial hypercholesterolemia	5C80.00	Whole blood	3.10E-03	6.99E-01	1.14E+00
Gastric cancer	2B72	Gastric tissue	6.27E-02	8.70E-01	1.59E+00
Glioblastopma	2A00.00	Nervous tissue	4.59E-01	-8.66E-02	-1.88E-01
Glioma	2A00.0Y-2A00.0Z	Brain stem tissue	7.54E-01	1.08E-03	2.87E-03
Glioma	2A00.0Y-2A00.0Z	White matter tissue	3.41E-01	-1.30E-01	-1.59E-01
Head and neck cancer	2D42	Head and neck tissue	1.35E-10	-6.80E-01	-8.52E-01
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	1.02E-01	1.36E-01	3.69E-01
Huntington's disease	8A01.10	Whole blood	7.01E-01	8.29E-03	7.43E-02
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	7.52E-01	5.99E-02	1.06E-01
Immunodeficiency	4A00-4A20	Peripheral blood	2.18E-01	-5.28E-02	-1.47E-01
Influenza	1E30	Whole blood	1.16E-01	-1.16E+00	-1.58E+00
Interstitial cystitis	GC00.3	Bladder tissue	1.69E-01	-3.64E-01	-6.98E-01
Intracranial aneurysm	8B01.0	Intracranial artery	2.67E-01	1.09E-02	4.46E-02
Irritable bowel syndrome	DD91.0	Rectal colon tissue	6.45E-01	-3.65E-02	-3.51E-02
Ischemic stroke	8B11	Peripheral blood	1.30E-01	-1.12E-01	-2.80E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	5.31E-01	5.85E-02	9.93E-02
Lateral sclerosis	8B60.4	Skin	8.31E-01	3.92E-02	6.69E-02
Lateral sclerosis	8B60.4	Cervical spinal cord	8.44E-01	2.57E-01	5.88E-01
Liver cancer	2C12.0	Liver tissue	1.84E-09	3.27E-01	8.90E-01
Liver failure	DB99.7-DB99.8	Liver tissue	2.90E-01	2.25E-01	6.53E-01
Lung cancer	2C25	Lung tissue	1.00E-51	6.60E-01	1.41E+00
Lupus erythematosus	4A40	Whole blood	2.05E-01	1.47E-01	1.62E-01
Major depressive disorder	6A70-6A7Z	Hippocampus	1.03E-01	1.26E-01	4.91E-01
Major depressive disorder	6A70-6A7Z	Whole blood	9.73E-01	3.52E-01	3.40E-01
Melanoma	2C30	Skin	2.19E-02	-1.03E+00	-6.99E-01
Multiple myeloma	2A83.1	Peripheral blood	1.73E-01	-3.12E-01	-4.61E-01
Multiple myeloma	2A83.1	Bone marrow	1.89E-04	4.31E-01	1.93E+00
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	5.69E-01	-1.60E-01	-4.11E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	6.02E-01	-2.93E-02	-8.90E-02
Myelofibrosis	2A20.2	Whole blood	2.61E-01	6.55E-02	2.76E-01
Myocardial infarction	BA41-BA50	Peripheral blood	8.45E-02	-4.55E-01	-4.94E-01
Myopathy	8C70.6	Muscle tissue	4.95E-03	3.98E-01	1.66E+00
Neonatal sepsis	KA60	Whole blood	1.82E-04	1.05E-01	4.51E-01
Neuroectodermal tumour	2A00.11	Brain stem tissue	2.91E-04	1.03E+00	1.98E+00
Non-alcoholic fatty liver disease	DB92	Liver tissue	8.82E-01	-1.42E-01	-1.69E+00
Obesity related type 2 diabetes	5A11	Omental adipose tissue	5.60E-01	1.85E-01	5.12E-01
Olive pollen allergy	CA08.00	Peripheral blood	1.01E-01	1.23E-01	2.84E-01
Oral cancer	2B6E	Oral tissue	6.37E-01	1.44E-01	1.87E-01
Osteoarthritis	FA00-FA0Z	Synovial tissue	2.43E-02	4.12E-01	1.16E+00
Osteoporosis	FB83.1	Bone marrow	4.07E-01	-1.57E-01	-2.75E-01
Ovarian cancer	2C73	Ovarian tissue	5.31E-08	1.57E+00	4.94E+00
Pancreatic cancer	2C10	Pancreas	6.47E-05	7.93E-01	1.36E+00
Parkinson's disease	8A00.0	Substantia nigra tissue	2.81E-01	-4.59E-02	-9.60E-02
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	7.99E-02	-1.24E-01	-4.68E-01
Pituitary cancer	2D12	Pituitary tissue	2.87E-01	1.35E-01	3.17E-01
Pituitary gonadotrope tumour	2D12	Pituitary tissue	4.53E-01	5.07E-01	1.05E+00
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	1.52E-01	-3.00E-02	-2.42E-01
Polycythemia vera	2A20.4	Whole blood	1.00E+00	-1.24E-03	-5.11E-03
Pompe disease	5C51.3	Biceps muscle	7.16E-01	6.16E-02	1.90E-01
Preterm birth	KA21.4Z	Myometrium	7.78E-01	-2.11E-01	-5.12E-01
Prostate cancer	2C82	Prostate	1.06E-04	1.86E+00	1.63E+00
Psoriasis	EA90	Skin	5.68E-19	8.91E-01	1.49E+00
Rectal cancer	2B92	Rectal colon tissue	2.22E-01	-2.77E-01	-4.25E-01
Renal cancer	2C90-2C91	Kidney	4.25E-07	1.41E+00	3.54E+00
Retinoblastoma	2D02.2	Uvea	1.28E-11	2.27E+00	6.80E+00
Rheumatoid arthritis	FA20	Synovial tissue	4.08E-02	2.53E-01	7.32E-01
Rhinovirus infection	CA42.1	Nasal epithelium tissue	5.94E-01	-1.54E-01	-3.72E-01
Schizophrenia	6A20	Prefrontal cortex	6.89E-02	-7.63E-02	-1.65E-01
Schizophrenia	6A20	Superior temporal cortex	7.35E-01	-7.43E-03	-5.45E-02
Scleroderma	4A42.Z	Whole blood	7.00E-01	5.55E-02	1.62E-01
Seizure	8A60-8A6Z	Whole blood	2.39E-01	-2.24E-01	-1.12E+00
Sensitive skin	EK0Z	Skin	6.56E-01	2.77E-02	9.33E-02
Sepsis with septic shock	1G41	Whole blood	8.71E-08	4.72E-02	1.84E-01
Shwachman-Diamond syndrome	3A70.0	Bone marrow	3.32E-01	-2.36E-01	-6.19E-01
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	8.66E-01	3.65E-02	2.47E-01
Simpson golabi behmel syndrome	LD2C	Adipose tissue	5.04E-01	1.24E-01	8.13E-01
Sjogren's syndrome	4A43.2	Salivary gland tissue	2.29E-01	1.67E-01	5.61E-01
Skin cancer	2C30-2C3Z	Skin	1.33E-01	1.58E-01	1.64E-01
Thrombocythemia	3B63	Whole blood	7.33E-01	-1.20E-01	-4.58E-01
Thrombocytopenia	3B64	Whole blood	7.93E-01	3.67E-02	3.63E-02
Thyroid cancer	2D10	Thyroid	6.60E-02	-1.00E-01	-1.94E-01
Tibial muscular dystrophy	8C75	Muscle tissue	1.97E-04	4.18E-01	2.17E+00
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	5.04E-02	-3.01E-01	-3.49E+00
Type 2 diabetes	5A11	Liver tissue	9.47E-01	-1.27E-01	-5.47E-01
Ureter cancer	2C92	Urothelium	3.24E-01	3.65E-03	2.61E-02
Uterine cancer	2C78	Endometrium tissue	2.25E-03	-4.80E-01	-3.99E-01
Vitiligo	ED63.0	Skin	3.46E-04	7.04E-01	2.22E+00