Details of the Drug-Related molecule(s) Expression Atlas

General Information of DME (ID: DEZS5YK)

• DME Name: Estradiol 17-beta-dehydrogenase 1 (HSD17B1) DME Info
• Gene Name: HSD17B1

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	2.55E-04	1.09E-01	3.39E-01
Alopecia	ED70	Skin from scalp	7.55E-01	-1.08E-02	-3.01E-02
Alzheimer's disease	8A20	Entorhinal cortex	8.14E-01	-4.78E-02	-2.97E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	3.22E-01	2.02E-01	1.19E+00
Aortic stenosis	BB70	Calcified aortic valve	3.33E-01	-1.22E-01	-6.69E-01
Apnea	7A40	Hyperplastic tonsil	2.34E-02	-8.56E-01	-4.12E+00
Arthropathy	FA00-FA5Z	Peripheral blood	3.47E-01	-9.20E-02	-5.07E-01
Asthma	CA23	Nasal and bronchial airway	1.36E-01	1.66E-01	3.62E-01
Atopic dermatitis	EA80	Skin	4.58E-04	4.18E-01	2.56E+00
Autism	6A02	Whole blood	1.17E-01	-5.15E-02	-3.01E-01
Autoimmune uveitis	9A96	Peripheral monocyte	6.80E-01	7.17E-02	7.67E-01
Autosomal dominant monocytopenia	4B04	Whole blood	8.99E-01	-1.04E-01	-3.73E-01
Bacterial infection of gingival	1C1H	Gingival tissue	2.64E-07	-3.01E-01	-1.02E+00
Batten disease	5C56.1	Whole blood	4.91E-01	5.83E-02	4.79E-01
Behcet's disease	4A62	Peripheral blood	5.25E-01	-5.44E-02	-3.79E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	2.38E-01	-3.75E-02	-3.12E-01
Bladder cancer	2C94	Bladder tissue	1.99E-02	1.64E-01	1.37E+00
Breast cancer	2C60-2C6Z	Breast tissue	4.27E-02	2.68E-02	4.68E-02
Cardioembolic stroke	8B11.20	Whole blood	1.42E-02	1.19E-01	6.80E-01
Cervical cancer	2C77	Cervical tissue	1.27E-01	-1.54E-01	-5.26E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	1.65E-02	-1.19E-01	-7.94E-01
Chronic hepatitis C	1E51.1	Whole blood	7.47E-01	-2.63E-02	-1.30E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	1.40E-01	-3.36E-02	-2.07E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	7.20E-01	5.99E-04	3.72E-03
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	3.06E-01	5.83E-02	3.97E-01
Colon cancer	2B90	Colon tissue	1.93E-16	1.58E-01	7.69E-01
Coronary artery disease	BA80-BA8Z	Peripheral blood	8.23E-01	7.22E-02	1.66E-01
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	2.10E-01	-3.63E-01	-2.36E+00
Endometriosis	GA10	Endometrium tissue	7.68E-01	-1.53E-02	-2.75E-02
Familial hypercholesterolemia	5C80.00	Peripheral blood	2.90E-02	7.81E-02	7.27E-01
Familial hypercholesterolemia	5C80.00	Whole blood	3.37E-03	1.97E-01	1.37E+00
Gastric cancer	2B72	Gastric tissue	9.83E-03	5.33E-01	3.78E+00
Glioblastopma	2A00.00	Nervous tissue	6.16E-13	1.20E-01	4.72E-01
Glioma	2A00.0Y-2A00.0Z	Brain stem tissue	6.46E-01	-3.06E-01	-5.83E-01
Glioma	2A00.0Y-2A00.0Z	White matter tissue	7.16E-01	2.01E-02	4.65E-02
Head and neck cancer	2D42	Head and neck tissue	7.01E-13	3.20E-01	1.34E+00
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	9.37E-01	7.36E-02	2.61E-01
Huntington's disease	8A01.10	Whole blood	4.30E-01	-1.45E-01	-7.25E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	2.19E-01	3.09E-02	2.08E-01
Immunodeficiency	4A00-4A20	Peripheral blood	3.94E-01	-1.56E-02	-1.32E-01
Influenza	1E30	Whole blood	2.47E-04	-3.45E-01	-6.62E+00
Interstitial cystitis	GC00.3	Bladder tissue	1.30E-02	-2.16E-01	-1.38E+00
Intracranial aneurysm	8B01.0	Intracranial artery	1.36E-01	1.64E-01	7.88E-01
Irritable bowel syndrome	DD91.0	Rectal colon tissue	4.03E-01	-4.99E-02	-1.67E-01
Ischemic stroke	8B11	Peripheral blood	5.02E-01	-6.99E-02	-4.09E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	5.05E-04	-1.75E-01	-4.80E-01
Lateral sclerosis	8B60.4	Skin	1.28E-01	-1.69E-01	-7.96E-01
Lateral sclerosis	8B60.4	Cervical spinal cord	1.46E-01	6.84E-02	2.15E-01
Liver cancer	2C12.0	Liver tissue	2.82E-01	-8.19E-03	-2.77E-02
Liver failure	DB99.7-DB99.8	Liver tissue	6.46E-01	1.46E-02	4.30E-02
Lung cancer	2C25	Lung tissue	1.80E-113	5.15E-01	2.49E+00
Lupus erythematosus	4A40	Whole blood	4.35E-01	1.06E-03	3.33E-03
Major depressive disorder	6A70-6A7Z	Hippocampus	8.07E-01	-2.65E-02	-2.47E-01
Major depressive disorder	6A70-6A7Z	Whole blood	9.92E-01	-1.86E-03	-5.37E-03
Melanoma	2C30	Skin	3.39E-02	2.15E-01	4.14E-01
Multiple myeloma	2A83.1	Peripheral blood	3.77E-01	-7.58E-02	-3.96E-01
Multiple myeloma	2A83.1	Bone marrow	2.99E-05	3.52E-01	2.45E+00
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	3.49E-02	-2.13E-01	-1.32E+00
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	2.09E-03	1.48E-01	8.02E-01
Myelofibrosis	2A20.2	Whole blood	1.99E-01	5.62E-02	5.68E-01
Myocardial infarction	BA41-BA50	Peripheral blood	9.85E-01	-1.88E-01	-3.40E-01
Myopathy	8C70.6	Muscle tissue	6.31E-01	-2.81E-02	-1.87E-01
Neonatal sepsis	KA60	Whole blood	9.76E-02	-2.01E-02	-9.45E-02
Neuroectodermal tumour	2A00.11	Brain stem tissue	1.39E-08	6.81E-01	3.66E+00
Non-alcoholic fatty liver disease	DB92	Liver tissue	7.49E-01	-1.08E-01	-5.05E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	1.61E-01	1.62E-01	9.10E-01
Olive pollen allergy	CA08.00	Peripheral blood	6.54E-01	-6.48E-03	-3.92E-02
Oral cancer	2B6E	Oral tissue	6.72E-02	3.76E-01	5.57E-01
Osteoarthritis	FA00-FA0Z	Synovial tissue	1.26E-01	2.05E-01	7.24E-01
Osteoporosis	FB83.1	Bone marrow	1.37E-01	1.25E-01	1.33E+00
Ovarian cancer	2C73	Ovarian tissue	9.40E-01	8.68E-02	2.17E-01
Pancreatic cancer	2C10	Pancreas	2.17E-03	1.69E-01	7.78E-01
Parkinson's disease	8A00.0	Substantia nigra tissue	2.71E-03	2.81E-01	1.32E+00
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	5.40E-01	6.03E-03	3.63E-02
Pituitary cancer	2D12	Pituitary tissue	5.31E-01	-9.80E-02	-4.04E-01
Pituitary gonadotrope tumour	2D12	Pituitary tissue	8.27E-01	-1.43E-01	-7.29E-01
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	8.36E-01	-1.64E-02	-2.32E-01
Polycythemia vera	2A20.4	Whole blood	1.11E-03	1.40E-02	1.23E-01
Pompe disease	5C51.3	Biceps muscle	3.36E-03	2.60E-01	1.52E+00
Preterm birth	KA21.4Z	Myometrium	5.10E-01	3.98E-02	8.41E-02
Prostate cancer	2C82	Prostate	1.49E-02	1.44E-01	3.14E-01
Psoriasis	EA90	Skin	1.21E-04	9.42E-02	2.39E-01
Rectal cancer	2B92	Rectal colon tissue	3.56E-02	-3.13E-01	-1.42E+00
Renal cancer	2C90-2C91	Kidney	5.45E-01	-4.51E-02	-2.21E-01
Retinoblastoma	2D02.2	Uvea	5.55E-07	6.00E-01	4.25E+00
Rheumatoid arthritis	FA20	Synovial tissue	9.57E-01	1.58E-01	5.02E-01
Rhinovirus infection	CA42.1	Nasal epithelium tissue	6.34E-01	2.88E-02	2.50E-01
Schizophrenia	6A20	Prefrontal cortex	2.24E-01	-3.18E-03	-1.65E-02
Schizophrenia	6A20	Superior temporal cortex	3.52E-01	-2.39E-02	-2.03E-01
Scleroderma	4A42.Z	Whole blood	2.28E-01	9.88E-02	7.92E-01
Seizure	8A60-8A6Z	Whole blood	7.74E-01	-6.11E-05	-3.77E-04
Sensitive skin	EK0Z	Skin	9.77E-01	-2.81E-02	-1.36E-01
Sepsis with septic shock	1G41	Whole blood	2.80E-03	6.64E-02	3.34E-01
Shwachman-Diamond syndrome	3A70.0	Bone marrow	3.45E-01	-6.18E-02	-2.99E-01
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	1.50E-03	-2.60E-01	-2.06E+00
Simpson golabi behmel syndrome	LD2C	Adipose tissue	6.61E-01	1.39E-01	4.41E-01
Sjogren's syndrome	4A43.2	Salivary gland tissue	1.47E-01	-5.84E-01	-1.54E+00
Skin cancer	2C30-2C3Z	Skin	2.06E-03	-2.51E-01	-6.02E-01
Thrombocythemia	3B63	Whole blood	7.33E-04	7.40E-02	7.42E-01
Thrombocytopenia	3B64	Whole blood	6.00E-01	4.73E-02	5.43E-02
Thyroid cancer	2D10	Thyroid	2.65E-11	-3.00E-01	-1.06E+00
Tibial muscular dystrophy	8C75	Muscle tissue	6.19E-01	-3.50E-02	-1.64E-01
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	3.39E-01	-7.12E-02	-3.77E-01
Type 2 diabetes	5A11	Liver tissue	5.03E-02	-8.80E-02	-6.92E-01
Ureter cancer	2C92	Urothelium	7.98E-01	-4.22E-02	-2.32E-01
Uterine cancer	2C78	Endometrium tissue	2.45E-04	-1.69E-01	-2.16E-01
Vitiligo	ED63.0	Skin	1.32E-01	1.78E-01	6.49E-01