Details of the Drug-Related molecule(s) Expression Atlas

General Information of DTP (ID: DT021JD)

• DTP Name: Organic anion transporting polypeptide 2A1 (SLCO2A1) DTP Info
• Gene Name: OATP2A1

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	4.08E-02	5.85E-02	2.32E-01
Adrenocortical carcinoma	2D11.Z	Kidney	1.56E-15	-1.19E+00	-2.32E+00
Alopecia	ED70	Skin from scalp	1.02E-04	3.66E-01	9.81E-01
Alzheimer's disease	8A20	Entorhinal cortex	3.03E-03	-9.85E-02	-3.19E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	6.83E-01	1.37E-02	1.20E-01
Aortic stenosis	BB70	Calcified aortic valve	3.41E-01	9.32E-01	7.63E-01
Apnea	7A40	Hyperplastic tonsil	7.32E-01	2.31E-01	3.89E-01
Arthropathy	FA00-FA5Z	Peripheral blood	9.40E-01	-2.86E-02	-1.60E-01
Asthma	CA23	Nasal and bronchial airway	2.33E-04	6.39E-01	5.01E-01
Atopic dermatitis	EA80	Skin	1.11E-07	3.78E-01	1.24E+00
Autism	6A02	Whole blood	7.26E-01	-2.93E-02	-1.15E-01
Autoimmune uveitis	9A96	Peripheral monocyte	2.18E-01	-1.28E-01	-5.03E-01
Autosomal dominant monocytopenia	4B04	Whole blood	5.60E-01	1.68E-01	1.33E+00
Bacterial infection of gingival	1C1H	Gingival tissue	1.96E-14	6.51E-01	1.55E+00
Batten disease	5C56.1	Whole blood	1.34E-02	2.09E-01	1.75E+00
Behcet's disease	4A62	Peripheral blood	5.76E-02	1.39E-01	5.46E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	7.35E-01	-9.97E-03	-3.55E-02
Bladder cancer	2C94	Bladder tissue	9.41E-01	-2.56E-03	-6.30E-03
Breast cancer	2C60-2C6Z	Breast tissue	8.24E-04	-1.27E-01	-2.76E-01
Cardioembolic stroke	8B11.20	Whole blood	6.92E-01	-5.97E-02	-2.17E-01
Cervical cancer	2C77	Cervical tissue	6.16E-05	-1.03E+00	-1.63E+00
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	9.58E-02	7.63E-02	4.56E-01
Chronic hepatitis C	1E51.1	Whole blood	1.87E-02	1.30E-01	8.38E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	2.10E-01	-3.06E-01	-4.11E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	1.01E-02	-1.02E-01	-2.09E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	1.61E-01	5.52E-01	2.12E+00
Colon cancer	2B90	Colon tissue	3.80E-104	-1.68E+00	-3.44E+00
Coronary artery disease	BA80-BA8Z	Peripheral blood	3.89E-01	-1.28E-01	-2.21E-01
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	4.16E-01	1.89E-02	1.01E-01
Endometriosis	GA10	Endometrium tissue	6.15E-01	-3.02E-02	-2.83E-02
Familial hypercholesterolemia	5C80.00	Peripheral blood	3.23E-01	-5.75E-02	-4.39E-01
Familial hypercholesterolemia	5C80.00	Whole blood	4.74E-01	2.24E-02	9.26E-02
Gastric cancer	2B72	Gastric tissue	1.61E-01	-6.16E-01	-1.41E+00
Glioblastopma	2A00.00	Nervous tissue	5.40E-06	9.54E-02	2.07E-01
Glioma	2A00.0Y-2A00.0Z	White matter tissue	5.33E-01	-2.56E-02	-1.18E-01
Head and neck cancer	2D42	Head and neck tissue	1.72E-09	5.68E-01	5.95E-01
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	3.47E-01	-2.39E-02	-9.91E-02
Huntington's disease	8A01.10	Whole blood	7.81E-02	2.43E-01	1.17E+00
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	2.92E-03	-8.71E-01	-1.79E+00
Immunodeficiency	4A00-4A20	Peripheral blood	9.41E-02	2.96E-02	2.02E-01
Influenza	1.00E+30	Whole blood	9.09E-01	-1.91E-02	-1.83E-01
Interstitial cystitis	GC00.3	Bladder tissue	3.38E-03	1.65E+00	4.86E+00
Intracranial aneurysm	8B01.0	Intracranial artery	5.97E-01	6.61E-01	8.84E-01
Irritable bowel syndrome	DD91.0	Rectal colon tissue	5.14E-01	-6.03E-02	-1.07E-01
Ischemic stroke	8B11	Peripheral blood	3.00E-01	1.52E-02	7.85E-02
Juvenile idiopathic arthritis	FA24	Peripheral blood	2.32E-01	8.23E-02	3.55E-01
Lateral sclerosis	8B60.4	Cervical spinal cord	6.79E-01	-1.14E-01	-5.55E-01
Lateral sclerosis	8B60.4	Skin	4.63E-01	7.07E-02	2.38E-01
Liver cancer	2C12.0	Liver tissue	1.36E-16	5.25E-01	1.78E+00
Liver failure	DB99.7-DB99.8	Liver tissue	7.81E-02	1.51E-01	5.53E-01
Lung cancer	2C25	Lung tissue	1.39E-96	-2.14E+00	-2.80E+00
Lupus erythematosus	4A40	Whole blood	1.58E-03	-2.17E-01	-4.50E-01
Major depressive disorder	6A70-6A7Z	Whole blood	4.86E-02	4.68E-02	2.26E-01
Major depressive disorder	6A70-6A7Z	Hippocampus	4.03E-01	7.34E-02	2.65E-01
Melanoma	2C30	Skin	2.79E-01	-6.58E-01	-5.16E-01
Multiple myeloma	2A83.1	Bone marrow	1.35E-03	-6.66E-01	-1.87E+00
Multiple myeloma	2A83.1	Peripheral blood	4.72E-01	-1.79E-02	-5.82E-02
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	2.15E-01	1.14E-01	6.15E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	2.94E-01	6.98E-02	2.04E-01
Myelofibrosis	2A20.2	Whole blood	3.73E-01	3.81E-02	2.22E-01
Myocardial infarction	BA41-BA50	Peripheral blood	3.06E-03	5.42E-01	1.03E+00
Myopathy	8C70.6	Muscle tissue	9.60E-01	-2.84E-02	-1.39E-01
Neonatal sepsis	KA60	Whole blood	5.62E-02	5.97E-02	2.75E-01
Neuroectodermal tumour	2A00.11	Brain stem tissue	5.00E-02	-6.23E-01	-1.05E+00
Non-alcoholic fatty liver disease	DB92	Liver tissue	5.30E-02	-9.11E-02	-4.58E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	2.40E-01	4.71E-01	8.52E-01
Olive pollen allergy	CA08.00	Peripheral blood	2.35E-01	2.74E-01	1.06E+00
Oral cancer	2B6E	Oral tissue	5.83E-01	-1.68E-01	-3.23E-01
Osteoarthritis	FA00-FA0Z	Synovial tissue	4.06E-01	3.99E-01	4.41E-01
Osteoporosis	FB83.1	Bone marrow	1.73E-02	1.85E-01	1.58E+00
Ovarian cancer	2C73	Ovarian tissue	8.68E-02	3.41E-01	3.48E-01
Pancreatic cancer	2C10	Pancreas	1.92E-03	-1.67E-01	-2.94E-01
Parkinson's disease	8A00.0	Substantia nigra tissue	1.15E-01	-1.35E-01	-3.72E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	8.36E-01	4.30E-03	2.49E-02
Pituitary cancer	2D12	Pituitary tissue	2.33E-02	-7.81E-01	-1.63E+00
Pituitary gonadotrope tumour	2D12	Pituitary tissue	1.63E-03	-1.19E+00	-2.07E+00
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	4.96E-01	2.21E-02	9.93E-02
Polycythemia vera	2A20.4	Whole blood	2.99E-04	1.16E-01	7.10E-01
Pompe disease	5C51.3	Biceps muscle	5.53E-01	2.00E-01	3.51E-01
Preterm birth	KA21.4Z	Myometrium	1.25E-01	7.78E-01	1.39E+00
Prostate cancer	2C82	Prostate	9.89E-02	1.98E-02	2.29E-02
Psoriasis	EA90	Skin	7.00E-02	2.00E-01	3.55E-01
Rectal cancer	2B92	Rectal colon tissue	1.38E-05	-6.83E-01	-3.50E+00
Renal cancer	2C90-2C91	Kidney	4.42E-01	-1.35E-01	-1.82E-01
Retinoblastoma	2D02.2	Uvea	2.13E-03	5.41E-01	2.93E+00
Rheumatoid arthritis	FA20	Synovial tissue	6.57E-01	8.24E-01	9.94E-01
Rhinovirus infection	CA42.1	Nasal epithelium tissue	8.38E-01	7.82E-02	2.07E-01
Schizophrenia	6A20	Prefrontal cortex	2.37E-01	-1.40E-01	-2.53E-01
Schizophrenia	6A20	Superior temporal cortex	8.04E-01	-4.46E-02	-3.24E-01
Scleroderma	4A42.Z	Whole blood	1.02E-01	-9.64E-02	-6.85E-01
Seizure	8A60-8A6Z	Whole blood	1.74E-01	-9.18E-02	-4.58E-01
Sensitive skin	EK0Z	Skin	1.47E-02	2.43E-01	2.29E+00
Sepsis with septic shock	1G41	Whole blood	1.65E-08	1.09E-01	5.22E-01
Shwachman-Diamond syndrome	3A70.0	Bone marrow	1.56E-01	5.23E-01	1.18E+00
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	5.98E-01	-1.32E-01	-2.94E-01
Simpson golabi behmel syndrome	LD2C	Adipose tissue	2.43E-01	1.29E-01	1.08E+00
Sjogren's syndrome	4A43.2	Salivary gland tissue	1.36E-01	4.82E-01	1.42E+00
Skin cancer	2C30-2C3Z	Skin	2.25E-02	-7.25E-02	-1.21E-01
Thrombocythemia	3B63	Whole blood	2.44E-02	1.41E-01	7.75E-01
Thrombocytopenia	3B64	Whole blood	1.58E-01	8.64E-01	1.77E+00
Thyroid cancer	2D10	Thyroid	7.70E-07	-2.59E-01	-5.72E-01
Tibial muscular dystrophy	8C75	Muscle tissue	7.05E-02	3.12E-01	8.18E-01
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	7.22E-01	2.19E-01	1.21E+00
Type 2 diabetes	5A11	Liver tissue	8.12E-01	1.01E-02	4.39E-02
Ureter cancer	2C92	Urothelium	1.87E-01	-7.38E-02	-4.29E-01
Uterine cancer	2C78	Endometrium tissue	4.01E-02	2.12E-01	1.95E-01
Vitiligo	ED63.0	Skin	5.50E-02	-2.01E-01	-4.79E-01