Details of the Drug-Related molecule(s) Expression Atlas

General Information of DTP (ID: DT06JWZ)

• DTP Name: Organic anion transporter 4 (SLC22A11) DTP Info
• Gene Name: OAT4

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	6.40E-01	-5.39E-02	-1.79E-01
Adrenocortical carcinoma	2D11.Z	Kidney	8.79E-01	-1.26E-01	-1.82E-01
Alopecia	ED70	Skin from scalp	3.72E-02	-9.47E-02	-4.93E-01
Alzheimer's disease	8A20	Entorhinal cortex	4.61E-04	-7.04E-02	-3.49E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	2.62E-01	-2.42E-01	-1.10E+00
Aortic stenosis	BB70	Calcified aortic valve	4.34E-01	3.72E-01	5.43E-01
Apnea	7A40	Hyperplastic tonsil	2.12E-01	-1.57E-01	-8.27E-01
Arthropathy	FA00-FA5Z	Peripheral blood	5.35E-01	1.40E-02	7.36E-02
Asthma	CA23	Nasal and bronchial airway	4.31E-03	-1.17E-01	-3.95E-01
Atopic dermatitis	EA80	Skin	5.82E-01	-1.98E-02	-1.27E-01
Autism	6A02	Whole blood	6.35E-01	-1.96E-03	-4.90E-03
Autoimmune uveitis	9A96	Peripheral monocyte	2.87E-01	-2.71E-01	-1.49E+00
Autosomal dominant monocytopenia	4B04	Whole blood	6.02E-01	7.41E-02	3.98E-01
Bacterial infection of gingival	1C1H	Gingival tissue	1.27E-01	3.04E-02	1.11E-01
Batten disease	5C56.1	Whole blood	8.65E-01	-1.45E-02	-1.28E-01
Behcet's disease	4A62	Peripheral blood	3.28E-01	1.14E-01	4.37E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	5.86E-01	-2.08E-02	-1.23E-01
Bladder cancer	2C94	Bladder tissue	3.10E-04	6.13E-01	1.98E+00
Breast cancer	2C60-2C6Z	Breast tissue	7.77E-09	-1.33E-01	-3.72E-01
Cardioembolic stroke	8B11.20	Whole blood	1.67E-04	1.21E-01	6.12E-01
Cervical cancer	2C77	Cervical tissue	3.93E-01	4.09E-03	1.12E-02
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	9.70E-01	9.40E-03	2.71E-02
Chronic hepatitis C	1E51.1	Whole blood	8.40E-01	1.38E-04	5.40E-04
Chronic obstructive pulmonary disease	CA22	Lung tissue	5.66E-02	5.09E-02	2.04E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	4.14E-01	5.87E-03	2.63E-02
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	1.66E-01	8.33E-02	4.59E-01
Colon cancer	2B90	Colon tissue	9.45E-02	1.82E-02	5.90E-02
Coronary artery disease	BA80-BA8Z	Peripheral blood	5.92E-01	-1.22E-01	-4.08E-01
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	2.05E-02	-1.13E-01	-3.35E-01
Endometriosis	GA10	Endometrium tissue	2.91E-01	9.91E-02	3.18E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	9.50E-01	-2.48E-03	-1.08E-02
Familial hypercholesterolemia	5C80.00	Whole blood	3.76E-03	-3.49E-01	-8.70E-01
Gastric cancer	2B72	Gastric tissue	9.61E-01	-3.67E-02	-5.95E-01
Glioblastopma	2A00.00	Nervous tissue	4.82E-06	-1.24E-01	-3.70E-01
Glioma	2A00.0Y-2A00.0Z	White matter tissue	6.77E-05	-4.29E-01	-3.07E+00
Head and neck cancer	2D42	Head and neck tissue	1.44E-03	9.52E-02	3.85E-01
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	2.63E-01	-7.85E-02	-2.11E-01
Huntington's disease	8A01.10	Whole blood	1.57E-01	8.42E-04	4.24E-03
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	3.18E-01	-1.53E-01	-6.16E-01
Immunodeficiency	4A00-4A20	Peripheral blood	9.91E-02	6.69E-02	3.89E-01
Influenza	1.00E+30	Whole blood	6.09E-03	2.80E-01	2.45E+00
Interstitial cystitis	GC00.3	Bladder tissue	7.31E-01	8.75E-02	4.42E-01
Intracranial aneurysm	8B01.0	Intracranial artery	4.92E-01	-3.38E-02	-1.72E-01
Irritable bowel syndrome	DD91.0	Rectal colon tissue	4.48E-01	-6.78E-03	-2.61E-02
Ischemic stroke	8B11	Peripheral blood	1.51E-01	2.36E-02	1.21E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	2.84E-01	-1.96E-02	-7.35E-02
Lateral sclerosis	8B60.4	Cervical spinal cord	9.67E-01	9.14E-02	5.47E-01
Lateral sclerosis	8B60.4	Skin	5.78E-01	8.83E-02	2.75E-01
Liver cancer	2C12.0	Liver tissue	8.58E-23	2.43E-01	9.75E-01
Liver failure	DB99.7-DB99.8	Liver tissue	4.67E-02	6.26E-01	5.98E+00
Lung cancer	2C25	Lung tissue	8.28E-01	-3.39E-03	-1.41E-02
Lupus erythematosus	4A40	Whole blood	1.75E-03	-2.86E-01	-3.96E-01
Major depressive disorder	6A70-6A7Z	Whole blood	7.33E-01	-4.60E-02	-1.63E-01
Major depressive disorder	6A70-6A7Z	Hippocampus	3.75E-01	-1.06E-02	-6.27E-02
Melanoma	2C30	Skin	2.22E-01	5.62E-01	7.13E-01
Multiple myeloma	2A83.1	Bone marrow	2.34E-05	-7.31E-01	-3.42E+00
Multiple myeloma	2A83.1	Peripheral blood	4.82E-02	8.62E-02	6.36E-01
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	6.66E-01	9.61E-02	1.76E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	4.85E-01	4.29E-02	1.84E-01
Myelofibrosis	2A20.2	Whole blood	6.69E-04	2.54E-01	9.37E-01
Myocardial infarction	BA41-BA50	Peripheral blood	5.44E-02	3.11E-01	5.05E-01
Myopathy	8C70.6	Muscle tissue	3.13E-01	-9.89E-02	-7.87E-01
Neonatal sepsis	KA60	Whole blood	4.46E-03	-1.44E-01	-3.63E-01
Neuroectodermal tumour	2A00.11	Brain stem tissue	3.01E-03	-7.90E-01	-1.44E+00
Non-alcoholic fatty liver disease	DB92	Liver tissue	2.63E-01	-1.25E-01	-7.02E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	8.13E-01	8.15E-02	5.69E-01
Olive pollen allergy	CA08.00	Peripheral blood	2.57E-02	1.46E-01	7.38E-01
Oral cancer	2B6E	Oral tissue	4.88E-07	-4.49E-01	-1.48E+00
Osteoarthritis	FA00-FA0Z	Synovial tissue	5.86E-01	1.66E-02	4.99E-02
Osteoporosis	FB83.1	Bone marrow	3.50E-01	7.37E-02	3.14E-01
Ovarian cancer	2C73	Ovarian tissue	5.04E-01	-4.21E-02	-1.56E-01
Pancreatic cancer	2C10	Pancreas	4.36E-02	-2.23E-01	-7.23E-01
Parkinson's disease	8A00.0	Substantia nigra tissue	2.69E-01	-9.08E-02	-4.66E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	3.28E-01	4.49E-02	2.28E-01
Pituitary cancer	2D12	Pituitary tissue	3.45E-01	6.96E-05	2.21E-04
Pituitary gonadotrope tumour	2D12	Pituitary tissue	8.48E-01	-2.33E-02	-7.56E-02
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	4.56E-01	-5.62E-03	-2.06E-02
Polycythemia vera	2A20.4	Whole blood	2.70E-08	3.13E-01	1.11E+00
Pompe disease	5C51.3	Biceps muscle	3.96E-01	-2.42E-02	-2.95E-01
Preterm birth	KA21.4Z	Myometrium	3.74E-01	1.62E-01	6.29E-01
Prostate cancer	2C82	Prostate	2.17E-02	-3.62E-01	-4.73E-01
Psoriasis	EA90	Skin	3.58E-06	-2.91E-01	-6.89E-01
Rectal cancer	2B92	Rectal colon tissue	6.13E-01	-1.88E-01	-6.40E-01
Renal cancer	2C90-2C91	Kidney	1.37E-01	-1.60E+00	-1.16E+00
Retinoblastoma	2D02.2	Uvea	2.01E-05	-3.25E-01	-2.06E+00
Rheumatoid arthritis	FA20	Synovial tissue	4.87E-01	3.39E-03	9.17E-03
Rhinovirus infection	CA42.1	Nasal epithelium tissue	3.30E-01	-1.57E-02	-1.30E-01
Schizophrenia	6A20	Prefrontal cortex	3.98E-01	3.30E-02	1.08E-01
Schizophrenia	6A20	Superior temporal cortex	8.93E-01	-4.67E-02	-2.64E-01
Scleroderma	4A42.Z	Whole blood	9.46E-02	-1.44E-01	-4.17E-01
Seizure	8A60-8A6Z	Whole blood	7.90E-01	4.82E-02	1.91E-01
Sensitive skin	EK0Z	Skin	8.93E-01	-1.09E-01	-3.75E-01
Sepsis with septic shock	1G41	Whole blood	2.94E-01	-9.11E-03	-2.24E-02
Shwachman-Diamond syndrome	3A70.0	Bone marrow	7.29E-02	4.83E-01	9.15E-01
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	8.83E-02	1.02E-01	4.48E-01
Simpson golabi behmel syndrome	LD2C	Adipose tissue	4.73E-01	7.40E-02	4.74E-01
Sjogren's syndrome	4A43.2	Salivary gland tissue	5.41E-01	-2.94E-01	-1.02E+00
Skin cancer	2C30-2C3Z	Skin	4.46E-07	-3.79E-01	-6.61E-01
Thrombocythemia	3B63	Whole blood	1.36E-04	4.02E-01	1.38E+00
Thrombocytopenia	3B64	Whole blood	5.01E-01	-2.78E-02	-1.67E-01
Thyroid cancer	2D10	Thyroid	1.75E-05	8.06E-02	4.03E-01
Tibial muscular dystrophy	8C75	Muscle tissue	1.48E-01	-2.47E-01	-1.48E+00
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	6.43E-01	4.62E-02	2.67E-01
Type 2 diabetes	5A11	Liver tissue	6.35E-01	-7.38E-02	-2.01E-01
Ureter cancer	2C92	Urothelium	7.19E-01	-1.94E-02	-7.05E-02
Uterine cancer	2C78	Endometrium tissue	3.62E-06	1.15E-01	3.28E-01
Vitiligo	ED63.0	Skin	3.06E-01	-7.12E-02	-5.85E-01