Details of the Drug-Related molecule(s) Expression Atlas

General Information of DTP (ID: DT0KQND)

• DTP Name: ATP-binding cassette sub-family B member 8 (ABCB8) DTP Info
• Gene Name: ABCB8

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	8.49E-03	7.48E-02	3.70E-01
Adrenocortical carcinoma	2D11.Z	Kidney	8.49E-02	2.84E-02	1.10E-01
Alopecia	ED70	Skin from scalp	3.28E-01	8.47E-02	2.57E-01
Alzheimer's disease	8A20	Entorhinal cortex	2.21E-08	-1.11E-01	-6.99E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	2.09E-01	8.43E-02	4.14E-01
Aortic stenosis	BB70	Calcified aortic valve	2.34E-01	2.28E-01	1.11E+00
Apnea	7A40	Hyperplastic tonsil	2.80E-01	-1.98E-01	-1.32E+00
Arthropathy	FA00-FA5Z	Peripheral blood	7.96E-01	-7.50E-02	-5.14E-01
Asthma	CA23	Nasal and bronchial airway	5.37E-01	2.95E-02	9.65E-02
Atopic dermatitis	EA80	Skin	2.72E-12	3.50E-01	2.98E+00
Autism	6A02	Whole blood	6.01E-01	3.37E-02	1.83E-01
Autoimmune uveitis	9A96	Peripheral monocyte	3.45E-01	-2.17E-02	-2.70E-01
Autosomal dominant monocytopenia	4B04	Whole blood	4.86E-01	4.94E-02	4.07E-01
Bacterial infection of gingival	1C1H	Gingival tissue	5.84E-01	-8.21E-03	-2.99E-02
Batten disease	5C56.1	Whole blood	2.99E-01	3.49E-02	2.26E-01
Behcet's disease	4A62	Peripheral blood	5.00E-01	-8.35E-02	-4.70E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	3.90E-01	-6.65E-03	-4.58E-02
Bladder cancer	2C94	Bladder tissue	8.97E-03	2.58E-01	1.35E+00
Breast cancer	2C60-2C6Z	Breast tissue	4.35E-80	3.87E-01	1.60E+00
Cardioembolic stroke	8B11.20	Whole blood	1.20E-02	-1.55E-01	-5.77E-01
Cervical cancer	2C77	Cervical tissue	2.04E-01	1.91E-02	1.30E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	4.22E-01	-5.12E-02	-2.32E-01
Chronic hepatitis C	1E51.1	Whole blood	4.07E-01	-4.58E-02	-2.60E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	6.35E-01	-1.92E-02	-1.06E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	9.36E-01	-3.57E-02	-1.36E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	2.17E-01	1.37E-02	1.17E-01
Colon cancer	2B90	Colon tissue	3.72E-02	4.62E-02	1.96E-01
Coronary artery disease	BA80-BA8Z	Peripheral blood	9.22E-01	-5.08E-02	-2.15E-01
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	8.70E-01	5.60E-02	1.23E-01
Endometriosis	GA10	Endometrium tissue	8.23E-01	6.63E-02	2.04E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	5.21E-01	6.68E-02	5.35E-01
Familial hypercholesterolemia	5C80.00	Whole blood	4.44E-02	-1.95E-01	-8.96E-01
Gastric cancer	2B72	Gastric tissue	4.94E-01	1.18E-01	3.61E-01
Glioblastopma	2A00.00	Nervous tissue	6.11E-52	-3.24E-01	-1.19E+00
Glioma	2A00.0Y-2A00.0Z	White matter tissue	1.24E-03	2.26E-01	9.74E-01
Head and neck cancer	2D42	Head and neck tissue	4.18E-11	-2.05E-01	-8.38E-01
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	7.69E-01	7.80E-02	4.11E-01
Huntington's disease	8A01.10	Whole blood	9.36E-01	6.56E-02	3.58E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	1.55E-02	2.69E-01	2.87E+00
Immunodeficiency	4A00-4A20	Peripheral blood	4.15E-01	4.95E-02	6.02E-01
Influenza	1.00E+30	Whole blood	2.15E-02	2.08E-01	2.09E+00
Interstitial cystitis	GC00.3	Bladder tissue	9.34E-01	-1.65E-02	-7.28E-02
Intracranial aneurysm	8B01.0	Intracranial artery	1.13E-01	2.50E-02	7.48E-02
Irritable bowel syndrome	DD91.0	Rectal colon tissue	8.76E-01	-1.79E-01	-3.92E-01
Ischemic stroke	8B11	Peripheral blood	2.15E-01	-4.62E-02	-2.73E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	3.25E-07	-3.78E-01	-8.85E-01
Lateral sclerosis	8B60.4	Cervical spinal cord	3.88E-01	7.98E-02	2.40E-01
Lateral sclerosis	8B60.4	Skin	7.18E-03	2.54E-01	4.13E+00
Liver cancer	2C12.0	Liver tissue	5.66E-01	2.16E-02	7.82E-02
Liver failure	DB99.7-DB99.8	Liver tissue	7.95E-01	1.01E-01	2.95E-01
Lung cancer	2C25	Lung tissue	1.15E-01	1.14E-02	5.14E-02
Lupus erythematosus	4A40	Whole blood	3.54E-02	1.45E-02	7.00E-02
Major depressive disorder	6A70-6A7Z	Whole blood	2.35E-01	-1.06E-01	-3.28E-01
Major depressive disorder	6A70-6A7Z	Hippocampus	2.88E-01	-1.55E-02	-1.50E-01
Melanoma	2C30	Skin	2.09E-01	-3.29E-01	-6.71E-01
Multiple myeloma	2A83.1	Bone marrow	2.76E-05	4.32E-01	3.26E+00
Multiple myeloma	2A83.1	Peripheral blood	6.89E-01	-5.95E-03	-2.17E-02
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	4.62E-01	2.62E-03	8.88E-03
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	4.89E-02	-1.13E-01	-8.99E-01
Myelofibrosis	2A20.2	Whole blood	3.22E-01	-7.33E-03	-9.82E-02
Myocardial infarction	BA41-BA50	Peripheral blood	1.49E-01	-7.03E-02	-2.06E-01
Myopathy	8C70.6	Muscle tissue	4.98E-02	-2.63E-01	-1.44E+00
Neonatal sepsis	KA60	Whole blood	8.04E-05	-1.34E-01	-6.65E-01
Neuroectodermal tumour	2A00.11	Brain stem tissue	1.62E-03	-3.43E-01	-1.67E+00
Non-alcoholic fatty liver disease	DB92	Liver tissue	8.45E-01	-1.75E-02	-8.03E-02
Obesity related type 2 diabetes	5A11	Omental adipose tissue	6.50E-01	-3.39E-02	-2.95E-01
Olive pollen allergy	CA08.00	Peripheral blood	5.92E-01	5.95E-02	1.05E+00
Oral cancer	2B6E	Oral tissue	1.14E-02	-1.80E-01	-6.55E-01
Osteoarthritis	FA00-FA0Z	Synovial tissue	4.62E-01	-2.27E-03	-4.08E-03
Osteoporosis	FB83.1	Bone marrow	3.26E-02	3.34E-01	1.59E+00
Ovarian cancer	2C73	Ovarian tissue	1.02E-01	-9.58E-02	-4.54E-01
Pancreatic cancer	2C10	Pancreas	4.30E-02	-2.56E-01	-7.68E-01
Parkinson's disease	8A00.0	Substantia nigra tissue	6.82E-01	7.05E-02	4.13E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	7.79E-01	4.20E-02	2.86E-01
Pituitary cancer	2D12	Pituitary tissue	9.19E-01	8.31E-02	2.38E-01
Pituitary gonadotrope tumour	2D12	Pituitary tissue	4.77E-01	3.43E-01	1.05E+00
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	8.49E-01	-5.33E-02	-4.70E-01
Polycythemia vera	2A20.4	Whole blood	1.92E-01	-2.80E-02	-3.51E-01
Pompe disease	5C51.3	Biceps muscle	6.26E-01	8.74E-04	4.69E-03
Preterm birth	KA21.4Z	Myometrium	3.38E-01	-9.04E-02	-1.95E-01
Prostate cancer	2C82	Prostate	6.82E-01	-9.00E-02	-2.49E-01
Psoriasis	EA90	Skin	4.48E-01	7.07E-02	2.48E-01
Rectal cancer	2B92	Rectal colon tissue	9.76E-01	1.60E-01	7.26E-01
Renal cancer	2C90-2C91	Kidney	5.23E-02	-1.81E-01	-8.27E-01
Retinoblastoma	2D02.2	Uvea	9.09E-01	7.66E-03	4.82E-02
Rheumatoid arthritis	FA20	Synovial tissue	8.68E-02	1.43E-01	6.16E-01
Rhinovirus infection	CA42.1	Nasal epithelium tissue	1.18E-01	1.99E-02	1.98E-01
Schizophrenia	6A20	Prefrontal cortex	1.46E-02	-8.88E-02	-5.47E-01
Schizophrenia	6A20	Superior temporal cortex	8.21E-01	-3.04E-02	-3.20E-01
Scleroderma	4A42.Z	Whole blood	1.20E-02	1.74E-01	9.36E-01
Seizure	8A60-8A6Z	Whole blood	8.91E-01	-1.04E-01	-4.86E-01
Sensitive skin	EK0Z	Skin	8.49E-01	-1.26E-01	-5.76E-01
Sepsis with septic shock	1G41	Whole blood	4.61E-01	-3.06E-02	-1.57E-01
Shwachman-Diamond syndrome	3A70.0	Bone marrow	6.79E-01	2.86E-02	1.64E-01
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	3.05E-01	6.15E-02	3.84E-01
Simpson golabi behmel syndrome	LD2C	Adipose tissue	7.29E-01	2.05E-01	6.46E-01
Sjogren's syndrome	4A43.2	Salivary gland tissue	3.24E-02	-2.04E-01	-1.87E+00
Skin cancer	2C30-2C3Z	Skin	4.43E-07	1.52E-01	4.84E-01
Thrombocythemia	3B63	Whole blood	7.66E-01	-2.04E-02	-2.30E-01
Thrombocytopenia	3B64	Whole blood	6.38E-01	6.71E-01	5.37E-01
Thyroid cancer	2D10	Thyroid	2.36E-12	-2.69E-01	-1.00E+00
Tibial muscular dystrophy	8C75	Muscle tissue	1.06E-02	-1.43E-01	-7.46E-01
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	5.44E-01	-3.56E-03	-3.39E-02
Type 2 diabetes	5A11	Liver tissue	3.66E-02	-2.30E-01	-1.37E+00
Ureter cancer	2C92	Urothelium	2.21E-01	-8.07E-03	-3.84E-02
Uterine cancer	2C78	Endometrium tissue	1.72E-16	-3.59E-01	-6.69E-01
Vitiligo	ED63.0	Skin	4.13E-01	-8.32E-02	-8.36E-01