Details of the Drug-Related molecule(s) Expression Atlas

General Information of DTP (ID: DT2CFQ5)

• DTP Name: Sodium- and chloride-dependent glycine transporter 1 (SLC6A9) DTP Info
• Gene Name: GLYT1

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	2.04E-03	-3.08E-01	-6.05E-01
Adrenocortical carcinoma	2D11.Z	Kidney	1.87E-01	-5.43E-01	-6.12E-01
Alopecia	ED70	Skin from scalp	3.80E-01	6.46E-02	2.00E-01
Alzheimer's disease	8A20	Entorhinal cortex	2.47E-03	2.14E-01	3.94E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	7.91E-01	2.32E-02	2.31E-01
Aortic stenosis	BB70	Calcified aortic valve	7.75E-01	3.16E-01	6.45E-01
Apnea	7A40	Hyperplastic tonsil	1.75E-01	-3.69E-01	-1.34E+00
Arthropathy	FA00-FA5Z	Peripheral blood	7.88E-01	7.11E-02	2.23E-01
Asthma	CA23	Nasal and bronchial airway	1.72E-06	-2.30E-01	-1.50E-01
Atopic dermatitis	EA80	Skin	3.87E-02	-4.61E-01	-6.97E-01
Autism	6A02	Whole blood	8.15E-03	-2.11E-01	-8.01E-01
Autoimmune uveitis	9A96	Peripheral monocyte	5.68E-02	-7.06E-02	-3.31E-01
Autosomal dominant monocytopenia	4B04	Whole blood	8.59E-01	2.91E-02	2.45E-01
Bacterial infection of gingival	1C1H	Gingival tissue	3.56E-01	-1.24E-01	-1.66E-01
Batten disease	5C56.1	Whole blood	9.28E-01	8.91E-03	6.77E-02
Behcet's disease	4A62	Peripheral blood	2.83E-01	0.00E+00	0.00E+00
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	1.16E-01	-5.14E-02	-3.41E-01
Bladder cancer	2C94	Bladder tissue	6.73E-01	-9.18E-02	-1.53E-01
Breast cancer	2C60-2C6Z	Breast tissue	8.86E-09	6.20E-02	1.58E-01
Cardioembolic stroke	8B11.20	Whole blood	9.81E-02	2.08E-01	4.18E-01
Cervical cancer	2C77	Cervical tissue	1.51E-03	1.21E-01	5.05E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	8.58E-01	3.15E-02	1.10E-01
Chronic hepatitis C	1E51.1	Whole blood	1.38E-01	7.86E-03	3.89E-02
Chronic obstructive pulmonary disease	CA22	Lung tissue	7.97E-01	2.50E-02	8.93E-02
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	8.56E-01	-4.71E-03	-6.86E-03
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	9.51E-01	9.49E-02	3.10E-01
Colon cancer	2B90	Colon tissue	1.25E-35	-6.98E-01	-1.27E+00
Coronary artery disease	BA80-BA8Z	Peripheral blood	2.38E-02	-3.17E-01	-2.27E+00
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	5.81E-01	-1.23E-01	-3.91E-01
Endometriosis	GA10	Endometrium tissue	3.95E-01	-1.07E-01	-3.65E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	8.46E-01	-8.47E-02	-3.98E-01
Familial hypercholesterolemia	5C80.00	Whole blood	1.43E-04	-6.44E-01	-1.52E+00
Gastric cancer	2B72	Gastric tissue	9.71E-01	-1.07E-01	-6.25E-01
Glioblastopma	2A00.00	Nervous tissue	1.37E-01	-3.52E-01	-5.48E-01
Glioma	2A00.0Y-2A00.0Z	White matter tissue	2.45E-03	-3.13E-01	-1.01E+00
Head and neck cancer	2D42	Head and neck tissue	1.92E-04	-2.35E-01	-5.16E-01
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	6.26E-01	-6.34E-02	-2.37E-01
Huntington's disease	8A01.10	Whole blood	7.35E-01	-4.47E-02	-3.44E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	3.55E-01	-2.04E-01	-7.09E-01
Immunodeficiency	4A00-4A20	Peripheral blood	8.96E-01	-1.05E-02	-9.02E-02
Influenza	1.00E+30	Whole blood	6.57E-02	2.40E-01	2.01E+00
Interstitial cystitis	GC00.3	Bladder tissue	7.14E-01	2.29E-02	7.22E-02
Intracranial aneurysm	8B01.0	Intracranial artery	7.74E-01	-3.56E-02	-1.52E-01
Irritable bowel syndrome	DD91.0	Rectal colon tissue	8.49E-01	5.91E-03	2.33E-02
Ischemic stroke	8B11	Peripheral blood	6.11E-01	1.93E-02	1.05E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	4.49E-03	6.50E-02	2.15E-01
Lateral sclerosis	8B60.4	Cervical spinal cord	2.73E-01	4.17E-02	2.31E-01
Lateral sclerosis	8B60.4	Skin	5.87E-01	-1.88E-01	-4.52E-01
Liver cancer	2C12.0	Liver tissue	5.40E-01	-6.28E-02	-2.12E-01
Liver failure	DB99.7-DB99.8	Liver tissue	9.59E-01	-3.71E-02	-1.67E-01
Lung cancer	2C25	Lung tissue	5.38E-15	-3.12E-01	-7.08E-01
Lupus erythematosus	4A40	Whole blood	2.21E-03	-2.42E-01	-5.21E-01
Major depressive disorder	6A70-6A7Z	Whole blood	1.82E-01	2.02E-02	8.65E-02
Major depressive disorder	6A70-6A7Z	Hippocampus	3.93E-01	-2.12E-02	-1.42E-01
Melanoma	2C30	Skin	3.75E-01	-2.38E-01	-2.65E-01
Multiple myeloma	2A83.1	Bone marrow	9.65E-03	5.02E-02	3.40E-01
Multiple myeloma	2A83.1	Peripheral blood	7.86E-01	6.00E-02	3.27E-01
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	2.47E-01	2.64E-01	5.81E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	9.23E-01	-5.55E-02	-2.44E-01
Myelofibrosis	2A20.2	Whole blood	3.93E-02	1.23E-01	6.25E-01
Myocardial infarction	BA41-BA50	Peripheral blood	2.00E-03	3.98E-01	8.45E-01
Myopathy	8C70.6	Muscle tissue	9.21E-01	6.52E-02	6.25E-01
Neonatal sepsis	KA60	Whole blood	2.47E-01	-6.55E-02	-1.85E-01
Neuroectodermal tumour	2A00.11	Brain stem tissue	1.36E-06	-1.72E+00	-3.62E+00
Non-alcoholic fatty liver disease	DB92	Liver tissue	6.36E-01	-1.17E-01	-4.80E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	4.23E-01	3.38E-02	1.91E-01
Olive pollen allergy	CA08.00	Peripheral blood	4.70E-01	2.29E-01	6.80E-01
Oral cancer	2B6E	Oral tissue	2.20E-03	-3.53E-01	-6.03E-01
Osteoarthritis	FA00-FA0Z	Synovial tissue	6.92E-01	-1.97E-01	-9.02E-01
Osteoporosis	FB83.1	Bone marrow	1.64E-02	5.73E-01	1.81E+00
Ovarian cancer	2C73	Ovarian tissue	2.17E-01	1.77E-01	4.52E-01
Pancreatic cancer	2C10	Pancreas	7.99E-01	-1.85E-03	-6.41E-03
Parkinson's disease	8A00.0	Substantia nigra tissue	6.10E-01	-3.57E-01	-8.09E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	2.89E-01	5.27E-02	3.70E-01
Pituitary cancer	2D12	Pituitary tissue	8.88E-02	1.03E-01	3.63E-01
Pituitary gonadotrope tumour	2D12	Pituitary tissue	1.05E-01	1.45E-01	4.05E-01
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	5.03E-02	1.06E-01	8.22E-01
Polycythemia vera	2A20.4	Whole blood	1.52E-05	2.22E-01	1.12E+00
Pompe disease	5C51.3	Biceps muscle	5.14E-01	-3.64E-02	-2.66E-01
Preterm birth	KA21.4Z	Myometrium	4.87E-01	-7.31E-02	-3.68E-01
Prostate cancer	2C82	Prostate	8.29E-01	-4.20E-02	-1.15E-01
Psoriasis	EA90	Skin	1.04E-01	-4.45E-01	-5.06E-01
Rectal cancer	2B92	Rectal colon tissue	7.39E-04	-4.62E-01	-2.19E+00
Renal cancer	2C90-2C91	Kidney	2.47E-01	2.31E-02	8.41E-02
Retinoblastoma	2D02.2	Uvea	3.72E-07	-1.48E+00	-2.77E+00
Rheumatoid arthritis	FA20	Synovial tissue	7.40E-01	1.39E-01	3.76E-01
Rhinovirus infection	CA42.1	Nasal epithelium tissue	4.76E-01	2.30E-02	8.47E-02
Schizophrenia	6A20	Prefrontal cortex	4.94E-01	-8.60E-02	-3.42E-01
Schizophrenia	6A20	Superior temporal cortex	1.64E-01	-3.45E-02	-1.71E-01
Scleroderma	4A42.Z	Whole blood	3.99E-01	6.88E-03	3.83E-02
Seizure	8A60-8A6Z	Whole blood	2.71E-01	-1.09E-01	-2.74E-01
Sensitive skin	EK0Z	Skin	2.14E-01	2.19E-01	5.08E-01
Sepsis with septic shock	1G41	Whole blood	3.19E-01	1.02E-01	3.03E-01
Shwachman-Diamond syndrome	3A70.0	Bone marrow	1.17E-02	4.31E-01	1.00E+00
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	8.11E-01	2.80E-02	1.49E-01
Simpson golabi behmel syndrome	LD2C	Adipose tissue	6.29E-01	-1.45E-02	-8.10E-02
Sjogren's syndrome	4A43.2	Salivary gland tissue	4.54E-01	-6.80E-02	-1.06E+00
Skin cancer	2C30-2C3Z	Skin	9.75E-27	-1.45E+00	-1.71E+00
Thrombocythemia	3B63	Whole blood	5.70E-02	1.75E-01	8.85E-01
Thrombocytopenia	3B64	Whole blood	7.54E-01	1.52E-02	9.04E-02
Thyroid cancer	2D10	Thyroid	1.63E-01	-6.58E-02	-2.24E-01
Tibial muscular dystrophy	8C75	Muscle tissue	2.48E-04	-2.03E-01	-8.82E-01
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	1.32E-01	1.76E-01	1.40E+00
Type 2 diabetes	5A11	Liver tissue	6.18E-01	-5.06E-02	-5.40E-01
Ureter cancer	2C92	Urothelium	5.87E-01	5.92E-02	4.11E-01
Uterine cancer	2C78	Endometrium tissue	1.73E-06	9.70E-02	3.26E-01
Vitiligo	ED63.0	Skin	6.17E-04	3.55E-01	2.56E+00