Details of the Drug-Related molecule(s) Expression Atlas

General Information of DTP (ID: DT2UQYR)

• DTP Name: Mitochondrial 2-oxodicarboxylate carrier (SLC25A21) DTP Info
• Gene Name: ODC

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	8.86E-37	-1.82E+00	-1.59E+00
Adrenocortical carcinoma	2D11.Z	Kidney	7.58E-01	-2.49E-02	-2.31E-01
Alopecia	ED70	Skin from scalp	5.18E-02	1.01E-01	2.64E-01
Alzheimer's disease	8A20	Entorhinal cortex	5.13E-01	1.09E-02	8.38E-02
Ankylosing spondylitis	FA92.0	Pheripheral blood	8.77E-01	1.20E-02	9.40E-02
Aortic stenosis	BB70	Calcified aortic valve	2.85E-01	3.83E-02	1.99E-01
Apnea	7A40	Hyperplastic tonsil	6.42E-01	-4.32E-02	-2.58E-01
Arthropathy	FA00-FA5Z	Peripheral blood	5.90E-01	-6.54E-03	-6.47E-02
Asthma	CA23	Nasal and bronchial airway	1.40E-01	-1.02E-01	-1.10E-01
Atopic dermatitis	EA80	Skin	3.39E-01	-7.20E-02	-2.89E-01
Autism	6A02	Whole blood	1.05E-01	2.64E-02	2.59E-01
Autoimmune uveitis	9A96	Peripheral monocyte	6.29E-02	8.37E-02	1.02E+00
Autosomal dominant monocytopenia	4B04	Whole blood	2.75E-01	-1.31E-02	-1.41E-01
Bacterial infection of gingival	1C1H	Gingival tissue	2.49E-05	-1.02E-01	-6.45E-01
Batten disease	5C56.1	Whole blood	7.73E-01	-4.42E-02	-5.68E-01
Behcet's disease	4A62	Peripheral blood	7.42E-01	-1.10E-03	-1.15E-02
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	8.27E-01	3.05E-03	2.90E-02
Bladder cancer	2C94	Bladder tissue	1.39E-01	4.12E-02	4.70E-01
Breast cancer	2C60-2C6Z	Breast tissue	2.40E-01	-7.24E-02	-2.57E-01
Cardioembolic stroke	8B11.20	Whole blood	3.12E-01	1.98E-02	1.53E-01
Cervical cancer	2C77	Cervical tissue	2.85E-01	-1.17E-01	-3.06E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	8.39E-01	5.30E-03	4.52E-02
Chronic hepatitis C	1E51.1	Whole blood	6.61E-01	1.07E-02	9.26E-02
Chronic obstructive pulmonary disease	CA22	Lung tissue	5.21E-01	1.12E-02	7.19E-02
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	4.27E-02	-5.40E-02	-3.79E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	7.76E-01	5.46E-02	2.56E-01
Colon cancer	2B90	Colon tissue	8.02E-06	-2.80E-02	-1.66E-01
Coronary artery disease	BA80-BA8Z	Peripheral blood	9.01E-01	-1.14E-01	-6.21E-01
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	4.43E-01	-4.47E-02	-3.82E-01
Endometriosis	GA10	Endometrium tissue	7.06E-01	5.20E-02	1.61E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	2.72E-01	-6.44E-02	-7.00E-01
Familial hypercholesterolemia	5C80.00	Whole blood	3.22E-02	-1.33E-01	-1.34E+00
Gastric cancer	2B72	Gastric tissue	7.43E-02	9.23E-02	5.01E-01
Glioblastopma	2A00.00	Nervous tissue	2.88E-36	8.41E-02	5.27E-01
Glioma	2A00.0Y-2A00.0Z	White matter tissue	1.45E-03	3.92E-01	1.24E+00
Head and neck cancer	2D42	Head and neck tissue	2.40E-07	-1.89E-01	-6.98E-01
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	2.13E-01	-2.58E-02	-2.09E-01
Huntington's disease	8A01.10	Whole blood	7.78E-01	-4.03E-02	-3.52E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	5.29E-01	-1.26E-01	-1.37E+00
Immunodeficiency	4A00-4A20	Peripheral blood	1.76E-02	3.99E-02	6.20E-01
Influenza	1.00E+30	Whole blood	9.83E-01	6.16E-02	5.25E-01
Interstitial cystitis	GC00.3	Bladder tissue	7.93E-02	-1.67E-01	-1.35E+00
Intracranial aneurysm	8B01.0	Intracranial artery	1.65E-02	-3.18E-01	-1.10E+00
Irritable bowel syndrome	DD91.0	Rectal colon tissue	4.09E-01	-7.62E-02	-1.91E-01
Ischemic stroke	8B11	Peripheral blood	4.30E-01	1.14E-02	1.55E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	5.04E-01	3.31E-02	8.31E-02
Lateral sclerosis	8B60.4	Cervical spinal cord	5.15E-02	1.42E-01	1.23E+00
Lateral sclerosis	8B60.4	Skin	6.72E-01	-2.61E-02	-1.84E-01
Liver cancer	2C12.0	Liver tissue	6.76E-02	-3.14E-02	-1.52E-01
Liver failure	DB99.7-DB99.8	Liver tissue	7.11E-02	-2.18E-01	-1.09E+00
Lung cancer	2C25	Lung tissue	3.86E-40	1.52E-01	7.24E-01
Lupus erythematosus	4A40	Whole blood	5.10E-02	4.65E-02	2.80E-01
Major depressive disorder	6A70-6A7Z	Whole blood	9.46E-02	4.16E-02	2.76E-01
Major depressive disorder	6A70-6A7Z	Hippocampus	9.90E-01	-2.56E-02	-2.31E-01
Melanoma	2C30	Skin	5.79E-02	-4.87E-01	-7.35E-01
Multiple myeloma	2A83.1	Bone marrow	2.92E-01	-4.11E-02	-4.53E-01
Multiple myeloma	2A83.1	Peripheral blood	8.83E-01	4.11E-02	3.93E-01
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	1.99E-01	-1.52E-01	-4.71E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	6.35E-01	1.53E-01	1.81E-01
Myelofibrosis	2A20.2	Whole blood	1.01E-01	1.55E-01	1.68E+00
Myocardial infarction	BA41-BA50	Peripheral blood	3.89E-01	1.89E-02	2.46E-02
Myopathy	8C70.6	Muscle tissue	5.21E-02	1.93E-01	1.02E+00
Neonatal sepsis	KA60	Whole blood	1.93E-01	2.44E-03	1.91E-02
Neuroectodermal tumour	2A00.11	Brain stem tissue	9.61E-10	1.75E-01	1.32E+00
Non-alcoholic fatty liver disease	DB92	Liver tissue	2.49E-01	-9.62E-02	-5.60E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	2.82E-02	-1.48E-01	-1.59E+00
Olive pollen allergy	CA08.00	Peripheral blood	7.94E-01	1.01E-01	5.71E-01
Oral cancer	2B6E	Oral tissue	4.43E-01	1.09E-03	4.22E-03
Osteoarthritis	FA00-FA0Z	Synovial tissue	8.94E-01	2.18E-02	1.04E-01
Osteoporosis	FB83.1	Bone marrow	1.80E-01	1.64E-01	8.24E-01
Ovarian cancer	2C73	Ovarian tissue	1.21E-01	-1.68E-01	-3.42E-01
Pancreatic cancer	2C10	Pancreas	1.58E-01	-1.24E-01	-3.66E-01
Parkinson's disease	8A00.0	Substantia nigra tissue	2.03E-01	-2.90E-02	-3.72E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	8.01E-01	1.23E-02	1.19E-01
Pituitary cancer	2D12	Pituitary tissue	7.51E-01	-1.76E-02	-9.70E-02
Pituitary gonadotrope tumour	2D12	Pituitary tissue	5.43E-02	7.88E-02	5.80E-01
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	8.95E-01	5.20E-02	3.01E-01
Polycythemia vera	2A20.4	Whole blood	1.19E-02	4.47E-02	4.70E-01
Pompe disease	5C51.3	Biceps muscle	4.97E-01	1.17E-01	4.64E-01
Preterm birth	KA21.4Z	Myometrium	3.05E-01	-4.25E-02	-1.31E+00
Prostate cancer	2C82	Prostate	5.11E-05	1.08E+00	1.69E+00
Psoriasis	EA90	Skin	7.01E-01	1.71E-02	5.97E-02
Rectal cancer	2B92	Rectal colon tissue	7.64E-02	-2.72E-01	-1.28E+00
Renal cancer	2C90-2C91	Kidney	2.01E-02	-1.80E-02	-7.36E-02
Retinoblastoma	2D02.2	Uvea	5.54E-02	-1.39E-01	-5.63E-01
Rheumatoid arthritis	FA20	Synovial tissue	4.25E-01	-1.33E-01	-6.60E-01
Rhinovirus infection	CA42.1	Nasal epithelium tissue	6.01E-01	2.63E-03	2.35E-02
Schizophrenia	6A20	Prefrontal cortex	7.88E-01	-2.69E-02	-2.32E-01
Schizophrenia	6A20	Superior temporal cortex	9.21E-01	4.21E-02	5.39E-01
Scleroderma	4A42.Z	Whole blood	9.23E-02	1.01E-01	7.27E-01
Seizure	8A60-8A6Z	Whole blood	6.93E-01	2.56E-02	1.66E-01
Sensitive skin	EK0Z	Skin	8.69E-01	7.34E-03	2.53E-02
Sepsis with septic shock	1G41	Whole blood	4.26E-06	6.30E-02	3.89E-01
Shwachman-Diamond syndrome	3A70.0	Bone marrow	7.25E-01	4.64E-01	5.87E-01
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	7.65E-01	1.13E-02	7.31E-02
Simpson golabi behmel syndrome	LD2C	Adipose tissue	6.75E-01	-4.37E-02	-1.99E-01
Sjogren's syndrome	4A43.2	Salivary gland tissue	8.24E-02	1.32E-01	1.67E+00
Skin cancer	2C30-2C3Z	Skin	7.56E-08	7.67E-02	1.76E-01
Thrombocythemia	3B63	Whole blood	5.87E-03	5.71E-02	6.09E-01
Thrombocytopenia	3B64	Whole blood	6.72E-01	1.76E-02	5.98E-02
Thyroid cancer	2D10	Thyroid	6.95E-01	-1.17E-01	-2.32E-01
Tibial muscular dystrophy	8C75	Muscle tissue	1.60E-01	-7.08E-02	-4.37E-01
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	9.58E-01	-8.16E-02	-4.91E-01
Type 2 diabetes	5A11	Liver tissue	9.69E-02	-5.36E-02	-7.85E-01
Ureter cancer	2C92	Urothelium	1.87E-01	3.88E-02	2.75E-01
Uterine cancer	2C78	Endometrium tissue	5.02E-01	-2.92E-02	-1.01E-01
Vitiligo	ED63.0	Skin	1.39E-01	-2.81E-01	-1.20E+00