Details of the Drug-Related molecule(s) Expression Atlas

General Information of DTP (ID: DT3D8F0)

• DTP Name: Organic anion transporting polypeptide 1B1 (SLCO1B1) DTP Info
• Gene Name: OATP1B1

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	9.49E-02	5.87E-03	5.86E-02
Adrenocortical carcinoma	2D11.Z	Kidney	2.07E-01	3.07E-02	2.01E-01
Alopecia	ED70	Skin from scalp	2.75E-01	2.07E-02	9.26E-02
Alzheimer's disease	8A20	Entorhinal cortex	8.15E-01	6.20E-03	5.61E-02
Ankylosing spondylitis	FA92.0	Pheripheral blood	9.87E-01	1.11E-02	1.24E-01
Aortic stenosis	BB70	Calcified aortic valve	6.85E-01	-5.08E-02	-1.72E-01
Apnea	7A40	Hyperplastic tonsil	4.99E-01	-2.54E-04	-2.46E-03
Arthropathy	FA00-FA5Z	Peripheral blood	6.69E-01	4.88E-03	3.78E-02
Asthma	CA23	Nasal and bronchial airway	4.30E-05	7.91E-02	3.70E-01
Atopic dermatitis	EA80	Skin	3.30E-02	4.23E-02	2.51E-01
Autism	6A02	Whole blood	5.07E-01	-5.21E-02	-2.97E-01
Autoimmune uveitis	9A96	Peripheral monocyte	2.63E-01	-5.35E-02	-3.52E-01
Autosomal dominant monocytopenia	4B04	Whole blood	1.60E-02	-1.16E-01	-1.37E+00
Bacterial infection of gingival	1C1H	Gingival tissue	1.58E-03	4.02E-02	2.15E-01
Batten disease	5C56.1	Whole blood	7.27E-01	-9.38E-02	-1.09E+00
Behcet's disease	4A62	Peripheral blood	1.09E-01	-3.03E-02	-1.51E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	3.89E-01	-1.75E-02	-1.15E-01
Bladder cancer	2C94	Bladder tissue	1.23E-02	1.36E-02	1.01E-01
Breast cancer	2C60-2C6Z	Breast tissue	9.12E-01	9.67E-03	3.43E-02
Cardioembolic stroke	8B11.20	Whole blood	6.46E-01	-7.72E-02	-3.41E-01
Cervical cancer	2C77	Cervical tissue	1.35E-02	-9.49E-02	-4.27E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	9.37E-01	2.74E-02	1.51E-01
Chronic hepatitis C	1E51.1	Whole blood	4.29E-01	-1.04E-03	-1.20E-02
Chronic obstructive pulmonary disease	CA22	Lung tissue	2.41E-01	-2.63E-02	-8.50E-02
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	5.54E-01	-1.65E-02	-1.24E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	7.69E-01	1.88E-02	2.46E-01
Colon cancer	2B90	Colon tissue	3.12E-09	7.77E-02	3.84E-01
Coronary artery disease	BA80-BA8Z	Peripheral blood	3.17E-01	6.66E-02	4.62E-01
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	2.93E-01	-1.09E-01	-3.82E-01
Endometriosis	GA10	Endometrium tissue	5.94E-01	-5.43E-03	-2.82E-02
Familial hypercholesterolemia	5C80.00	Peripheral blood	3.75E-01	6.66E-02	5.58E-01
Familial hypercholesterolemia	5C80.00	Whole blood	3.27E-01	-5.78E-02	-3.84E-01
Gastric cancer	2B72	Gastric tissue	9.20E-01	-1.59E-03	-9.27E-03
Glioblastopma	2A00.00	Nervous tissue	1.28E-02	-3.03E-02	-1.77E-01
Glioma	2A00.0Y-2A00.0Z	White matter tissue	1.27E-01	-1.70E-01	-5.42E-01
Head and neck cancer	2D42	Head and neck tissue	8.73E-01	1.50E-03	9.14E-03
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	2.68E-01	-3.85E-02	-3.86E-01
Huntington's disease	8A01.10	Whole blood	2.23E-01	-6.79E-02	-4.89E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	6.11E-01	-1.87E-01	-9.80E-01
Immunodeficiency	4A00-4A20	Peripheral blood	2.21E-01	-5.57E-02	-6.30E-01
Influenza	1.00E+30	Whole blood	1.58E-01	1.80E-01	1.63E+00
Interstitial cystitis	GC00.3	Bladder tissue	1.67E-02	7.40E-02	1.58E+00
Intracranial aneurysm	8B01.0	Intracranial artery	5.08E-01	-9.92E-02	-5.05E-01
Irritable bowel syndrome	DD91.0	Rectal colon tissue	7.76E-01	-8.58E-03	-4.87E-02
Ischemic stroke	8B11	Peripheral blood	8.66E-01	1.67E-02	1.04E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	3.41E-01	9.35E-02	3.49E-01
Lateral sclerosis	8B60.4	Cervical spinal cord	7.81E-01	-1.08E-01	-5.41E-01
Lateral sclerosis	8B60.4	Skin	5.23E-01	-1.00E-01	-3.26E-01
Liver cancer	2C12.0	Liver tissue	1.45E-26	-1.31E+00	-2.12E+00
Liver failure	DB99.7-DB99.8	Liver tissue	1.73E-03	-4.33E+00	-7.79E+00
Lung cancer	2C25	Lung tissue	2.80E-34	1.44E-01	9.71E-01
Lupus erythematosus	4A40	Whole blood	3.56E-04	5.83E-02	1.92E-01
Major depressive disorder	6A70-6A7Z	Whole blood	2.86E-01	9.09E-03	4.61E-02
Major depressive disorder	6A70-6A7Z	Hippocampus	8.47E-01	1.14E-02	8.20E-02
Melanoma	2C30	Skin	1.12E-01	-7.30E-02	-1.37E-01
Multiple myeloma	2A83.1	Bone marrow	1.50E-04	1.94E-01	2.06E+00
Multiple myeloma	2A83.1	Peripheral blood	6.86E-01	3.72E-02	2.86E-01
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	3.23E-01	6.36E-02	5.84E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	9.55E-01	1.20E-02	9.21E-02
Myelofibrosis	2A20.2	Whole blood	3.14E-04	9.49E-02	8.25E-01
Myocardial infarction	BA41-BA50	Peripheral blood	1.73E-02	1.07E-01	2.61E-01
Myopathy	8C70.6	Muscle tissue	4.62E-01	-8.97E-03	-6.28E-02
Neonatal sepsis	KA60	Whole blood	2.70E-01	-2.71E-02	-1.46E-01
Neuroectodermal tumour	2A00.11	Brain stem tissue	6.37E-01	-1.96E-03	-1.14E-02
Non-alcoholic fatty liver disease	DB92	Liver tissue	2.00E-02	7.38E-01	9.90E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	5.57E-01	1.53E-02	1.76E-01
Olive pollen allergy	CA08.00	Peripheral blood	1.25E-01	-8.96E-02	-5.03E-01
Oral cancer	2B6E	Oral tissue	2.47E-04	1.32E-01	7.89E-01
Osteoarthritis	FA00-FA0Z	Synovial tissue	9.30E-01	7.68E-02	3.82E-01
Osteoporosis	FB83.1	Bone marrow	7.68E-02	1.80E-01	1.25E+00
Ovarian cancer	2C73	Ovarian tissue	5.40E-01	-3.16E-02	-1.22E-01
Pancreatic cancer	2C10	Pancreas	9.07E-02	-9.94E-02	-5.12E-01
Parkinson's disease	8A00.0	Substantia nigra tissue	8.03E-01	8.37E-02	4.07E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	2.07E-01	5.26E-02	4.81E-01
Pituitary cancer	2D12	Pituitary tissue	1.88E-02	1.77E-01	9.29E-01
Pituitary gonadotrope tumour	2D12	Pituitary tissue	6.46E-02	2.08E-01	1.09E+00
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	3.33E-01	-5.25E-03	-4.09E-02
Polycythemia vera	2A20.4	Whole blood	3.85E-09	1.32E-01	1.12E+00
Pompe disease	5C51.3	Biceps muscle	1.38E-01	-1.46E-01	-1.22E+00
Preterm birth	KA21.4Z	Myometrium	7.18E-01	-5.08E-02	-4.53E-01
Prostate cancer	2C82	Prostate	7.59E-01	-3.08E-02	-1.64E-01
Psoriasis	EA90	Skin	3.65E-04	-1.54E-01	-7.81E-01
Rectal cancer	2B92	Rectal colon tissue	2.48E-01	-8.99E-02	-4.81E-01
Renal cancer	2C90-2C91	Kidney	6.76E-03	8.67E-02	6.17E-01
Retinoblastoma	2D02.2	Uvea	3.26E-02	1.34E-01	1.81E+00
Rheumatoid arthritis	FA20	Synovial tissue	5.71E-01	-1.33E-02	-6.44E-02
Rhinovirus infection	CA42.1	Nasal epithelium tissue	3.13E-01	3.50E-03	3.41E-02
Schizophrenia	6A20	Prefrontal cortex	9.01E-01	3.70E-03	2.13E-02
Schizophrenia	6A20	Superior temporal cortex	9.70E-01	2.57E-03	2.16E-02
Scleroderma	4A42.Z	Whole blood	1.26E-03	2.42E-01	1.68E+00
Seizure	8A60-8A6Z	Whole blood	4.28E-01	-5.35E-02	-3.18E-01
Sensitive skin	EK0Z	Skin	4.49E-01	-1.07E-01	-8.21E-01
Sepsis with septic shock	1G41	Whole blood	2.45E-01	3.59E-02	1.70E-01
Shwachman-Diamond syndrome	3A70.0	Bone marrow	5.08E-01	-2.87E-02	-2.90E-01
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	1.90E-01	8.99E-03	9.09E-02
Simpson golabi behmel syndrome	LD2C	Adipose tissue	9.30E-01	6.08E-02	3.23E-01
Sjogren's syndrome	4A43.2	Salivary gland tissue	1.00E-01	-3.29E-01	-1.92E+00
Skin cancer	2C30-2C3Z	Skin	2.65E-04	5.83E-02	1.94E-01
Thrombocythemia	3B63	Whole blood	2.66E-02	2.54E-02	2.28E-01
Thrombocytopenia	3B64	Whole blood	9.08E-02	1.19E-01	5.19E-01
Thyroid cancer	2D10	Thyroid	5.98E-03	9.85E-03	5.46E-02
Tibial muscular dystrophy	8C75	Muscle tissue	1.37E-01	-9.96E-02	-4.51E-01
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	2.24E-01	5.34E-02	6.68E-01
Type 2 diabetes	5A11	Liver tissue	2.81E-01	3.67E-02	2.82E-01
Ureter cancer	2C92	Urothelium	9.93E-01	-8.70E-02	-4.54E-01
Uterine cancer	2C78	Endometrium tissue	1.12E-01	8.17E-03	5.03E-02
Vitiligo	ED63.0	Skin	5.69E-01	-2.82E-02	-1.27E-01