Details of the Drug-Related molecule(s) Expression Atlas

General Information of DTP (ID: DT3I124)

• DTP Name: Monocarboxylate transporter 6 (SLC16A5) DTP Info
• Gene Name: MCT6

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	3.08E-05	1.47E-01	3.73E-01
Adrenocortical carcinoma	2D11.Z	Kidney	3.35E-01	9.96E-03	4.87E-02
Alopecia	ED70	Skin from scalp	1.47E-03	2.92E-01	9.05E-01
Alzheimer's disease	8A20	Entorhinal cortex	4.08E-01	4.22E-03	2.64E-02
Ankylosing spondylitis	FA92.0	Pheripheral blood	1.49E-01	1.39E-01	4.49E-01
Aortic stenosis	BB70	Calcified aortic valve	9.52E-01	8.61E-02	4.15E-01
Apnea	7A40	Hyperplastic tonsil	9.09E-02	-3.48E-01	-1.70E+00
Arthropathy	FA00-FA5Z	Peripheral blood	3.05E-01	3.09E-02	9.47E-02
Asthma	CA23	Nasal and bronchial airway	3.45E-02	8.27E-02	1.46E-01
Atopic dermatitis	EA80	Skin	1.85E-02	-2.22E-01	-1.13E+00
Autism	6A02	Whole blood	2.91E-01	1.07E-01	3.67E-01
Autoimmune uveitis	9A96	Peripheral monocyte	9.93E-02	3.89E-01	7.79E-01
Autosomal dominant monocytopenia	4B04	Whole blood	9.64E-01	-5.14E-02	-1.10E-01
Bacterial infection of gingival	1C1H	Gingival tissue	8.03E-05	-1.43E-01	-4.87E-01
Batten disease	5C56.1	Whole blood	5.34E-01	-4.13E-02	-1.73E-01
Behcet's disease	4A62	Peripheral blood	8.82E-01	-1.47E-02	-6.42E-02
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	6.71E-01	-7.67E-03	-4.82E-02
Bladder cancer	2C94	Bladder tissue	1.30E-03	-1.78E+00	-2.55E+00
Breast cancer	2C60-2C6Z	Breast tissue	2.50E-06	1.51E-01	3.39E-01
Cardioembolic stroke	8B11.20	Whole blood	1.86E-01	9.21E-02	2.79E-01
Cervical cancer	2C77	Cervical tissue	3.72E-02	-1.05E-01	-2.35E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	6.22E-01	1.85E-01	1.86E-01
Chronic hepatitis C	1E51.1	Whole blood	9.19E-01	-3.39E-01	-5.96E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	2.49E-02	-2.38E-01	-7.08E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	7.70E-02	3.90E-02	1.08E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	2.19E-02	-6.10E-01	-1.61E+00
Colon cancer	2B90	Colon tissue	3.92E-36	-5.28E-01	-1.29E+00
Coronary artery disease	BA80-BA8Z	Peripheral blood	8.69E-01	8.01E-02	9.20E-02
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	3.91E-01	-1.15E-01	-3.40E-01
Endometriosis	GA10	Endometrium tissue	1.02E-02	-2.20E-01	-6.94E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	2.08E-01	-1.21E-01	-6.07E-01
Familial hypercholesterolemia	5C80.00	Whole blood	4.03E-04	4.58E-01	1.76E+00
Gastric cancer	2B72	Gastric tissue	6.02E-01	-1.06E-01	-1.09E-01
Glioblastopma	2A00.00	Nervous tissue	2.47E-01	-1.16E-02	-5.95E-02
Glioma	2A00.0Y-2A00.0Z	White matter tissue	2.44E-01	-3.29E-01	-7.01E-01
Head and neck cancer	2D42	Head and neck tissue	1.59E-14	-6.93E-01	-5.51E-01
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	7.64E-01	-1.03E-01	-4.19E-01
Huntington's disease	8A01.10	Whole blood	2.40E-01	2.17E-01	5.35E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	5.41E-01	1.29E-01	2.11E-01
Immunodeficiency	4A00-4A20	Peripheral blood	6.39E-01	-6.06E-02	-3.49E-01
Influenza	1.00E+30	Whole blood	3.37E-01	-5.45E-01	-1.16E+00
Interstitial cystitis	GC00.3	Bladder tissue	6.52E-05	-1.62E+00	-3.83E+00
Intracranial aneurysm	8B01.0	Intracranial artery	4.97E-03	3.94E-01	1.72E+00
Irritable bowel syndrome	DD91.0	Rectal colon tissue	7.83E-01	-7.45E-02	-1.12E-01
Ischemic stroke	8B11	Peripheral blood	2.97E-01	1.03E-01	2.86E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	8.39E-03	-2.32E-01	-3.92E-01
Lateral sclerosis	8B60.4	Cervical spinal cord	3.15E-02	1.43E-01	7.90E-01
Lateral sclerosis	8B60.4	Skin	1.56E-01	-1.25E-01	-8.55E-01
Liver cancer	2C12.0	Liver tissue	6.09E-11	-3.05E-01	-1.39E+00
Liver failure	DB99.7-DB99.8	Liver tissue	4.11E-01	9.54E-02	3.47E-01
Lung cancer	2C25	Lung tissue	7.47E-44	-5.20E-01	-1.46E+00
Lupus erythematosus	4A40	Whole blood	8.04E-08	2.44E-01	4.50E-01
Major depressive disorder	6A70-6A7Z	Whole blood	3.83E-01	2.16E-02	4.92E-02
Major depressive disorder	6A70-6A7Z	Hippocampus	5.28E-01	8.20E-03	5.08E-02
Melanoma	2C30	Skin	1.03E-02	-6.16E-01	-7.74E-01
Multiple myeloma	2A83.1	Bone marrow	7.77E-03	-2.05E-01	-1.45E+00
Multiple myeloma	2A83.1	Peripheral blood	5.19E-01	4.41E-02	3.31E-01
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	9.88E-01	6.68E-02	5.15E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	1.26E-02	1.92E-01	5.18E-01
Myelofibrosis	2A20.2	Whole blood	7.37E-01	2.26E-01	9.53E-01
Myocardial infarction	BA41-BA50	Peripheral blood	1.51E-02	2.72E-01	4.77E-01
Myopathy	8C70.6	Muscle tissue	4.10E-02	1.68E-01	1.04E+00
Neonatal sepsis	KA60	Whole blood	2.89E-12	4.79E-01	1.15E+00
Neuroectodermal tumour	2A00.11	Brain stem tissue	4.50E-01	-2.01E-01	-7.60E-01
Non-alcoholic fatty liver disease	DB92	Liver tissue	2.58E-01	-2.71E-02	-3.66E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	1.84E-01	-1.07E-01	-1.24E+00
Olive pollen allergy	CA08.00	Peripheral blood	4.41E-01	-6.74E-03	-2.20E-02
Oral cancer	2B6E	Oral tissue	1.49E-01	8.79E-02	1.62E-01
Osteoarthritis	FA00-FA0Z	Synovial tissue	9.22E-01	-1.31E-01	-2.74E-01
Osteoporosis	FB83.1	Bone marrow	9.54E-02	2.65E-01	1.07E+00
Ovarian cancer	2C73	Ovarian tissue	1.76E-03	5.28E-01	1.23E+00
Pancreatic cancer	2C10	Pancreas	6.34E-05	5.95E-01	1.12E+00
Parkinson's disease	8A00.0	Substantia nigra tissue	8.89E-01	1.58E-02	1.15E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	7.17E-03	1.42E-01	5.36E-01
Pituitary cancer	2D12	Pituitary tissue	4.48E-01	6.51E-02	1.83E-01
Pituitary gonadotrope tumour	2D12	Pituitary tissue	9.73E-01	1.36E-01	4.24E-01
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	5.18E-01	-6.35E-02	-3.87E-01
Polycythemia vera	2A20.4	Whole blood	2.86E-01	1.02E-03	4.03E-03
Pompe disease	5C51.3	Biceps muscle	1.35E-07	2.20E+00	8.56E+00
Preterm birth	KA21.4Z	Myometrium	3.86E-01	4.64E-02	3.29E-01
Prostate cancer	2C82	Prostate	8.07E-05	-1.31E+00	-1.79E+00
Psoriasis	EA90	Skin	1.97E-06	1.84E-01	6.05E-01
Rectal cancer	2B92	Rectal colon tissue	1.09E-01	-5.10E-01	-9.40E-01
Renal cancer	2C90-2C91	Kidney	1.60E-06	-1.56E+00	-3.11E+00
Retinoblastoma	2D02.2	Uvea	8.26E-16	2.45E+00	1.20E+01
Rheumatoid arthritis	FA20	Synovial tissue	5.84E-01	2.09E-01	3.61E-01
Rhinovirus infection	CA42.1	Nasal epithelium tissue	1.49E-01	-3.51E-02	-1.32E-01
Schizophrenia	6A20	Prefrontal cortex	8.65E-02	5.64E-02	7.10E-02
Schizophrenia	6A20	Superior temporal cortex	4.83E-01	-4.56E-02	-2.78E-01
Scleroderma	4A42.Z	Whole blood	8.09E-06	4.39E-01	2.84E+00
Seizure	8A60-8A6Z	Whole blood	3.80E-01	-1.42E-01	-4.31E-01
Sensitive skin	EK0Z	Skin	3.94E-01	-3.50E-02	-1.34E-01
Sepsis with septic shock	1G41	Whole blood	3.29E-35	5.80E-01	1.50E+00
Shwachman-Diamond syndrome	3A70.0	Bone marrow	7.46E-03	-6.24E-01	-2.42E+00
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	5.40E-01	1.42E-01	5.19E-01
Simpson golabi behmel syndrome	LD2C	Adipose tissue	8.20E-01	-2.57E-01	-4.43E-01
Sjogren's syndrome	4A43.2	Salivary gland tissue	3.22E-01	-4.33E-02	-3.02E-01
Skin cancer	2C30-2C3Z	Skin	1.46E-24	-5.01E-01	-1.31E+00
Thrombocythemia	3B63	Whole blood	3.17E-01	-4.36E-02	-1.87E-01
Thrombocytopenia	3B64	Whole blood	3.74E-01	8.09E-01	6.09E-01
Thyroid cancer	2D10	Thyroid	2.82E-29	-7.05E-01	-1.67E+00
Tibial muscular dystrophy	8C75	Muscle tissue	2.37E-01	2.42E-01	4.34E-01
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	1.11E-02	2.68E-01	4.84E+00
Type 2 diabetes	5A11	Liver tissue	2.75E-01	-6.05E-02	-2.21E-01
Ureter cancer	2C92	Urothelium	2.91E-01	-2.44E-01	-8.41E-01
Uterine cancer	2C78	Endometrium tissue	1.61E-03	-2.80E-01	-4.20E-01
Vitiligo	ED63.0	Skin	2.12E-01	9.09E-02	6.09E-01