Details of the Drug-Related molecule(s) Expression Atlas

General Information of DTP (ID: DT8Z563)

• DTP Name: Sodium- and chloride-dependent GABA transporter 1 (SLC6A1) DTP Info
• Gene Name: GABT1

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	8.85E-02	5.66E-04	4.38E-03
Adrenocortical carcinoma	2D11.Z	Kidney	3.12E-01	-2.38E-02	-5.94E-02
Alopecia	ED70	Skin from scalp	3.47E-01	-2.20E-01	-3.73E-01
Alzheimer's disease	8A20	Entorhinal cortex	7.12E-02	-1.09E-01	-2.65E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	8.17E-01	6.64E-04	5.12E-03
Aortic stenosis	BB70	Calcified aortic valve	6.44E-02	-5.31E-01	-7.53E-01
Apnea	7A40	Hyperplastic tonsil	3.06E-01	3.35E-01	1.11E+00
Arthropathy	FA00-FA5Z	Peripheral blood	1.37E-01	-2.40E-02	-1.54E-01
Asthma	CA23	Nasal and bronchial airway	9.90E-01	-1.45E-02	-3.34E-02
Atopic dermatitis	EA80	Skin	5.55E-03	2.46E-01	8.54E-01
Autism	6A02	Whole blood	4.85E-01	1.90E-02	1.63E-01
Autoimmune uveitis	9A96	Peripheral monocyte	1.32E-01	-1.82E-01	-1.34E+00
Autosomal dominant monocytopenia	4B04	Whole blood	9.22E-01	3.60E-02	3.03E-01
Bacterial infection of gingival	1C1H	Gingival tissue	2.76E-06	1.30E-01	7.18E-01
Batten disease	5C56.1	Whole blood	5.52E-01	5.01E-02	6.15E-01
Behcet's disease	4A62	Peripheral blood	6.45E-01	4.64E-03	1.62E-02
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	2.34E-01	1.08E-01	4.74E-01
Bladder cancer	2C94	Bladder tissue	1.29E-03	4.88E-01	2.15E+00
Breast cancer	2C60-2C6Z	Breast tissue	8.62E-25	1.41E-01	5.37E-01
Cardioembolic stroke	8B11.20	Whole blood	4.75E-01	1.15E-02	8.89E-02
Cervical cancer	2C77	Cervical tissue	8.54E-01	6.03E-02	1.75E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	1.81E-01	3.15E-02	3.35E-01
Chronic hepatitis C	1E51.1	Whole blood	7.70E-01	-8.72E-03	-1.40E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	4.84E-01	-2.91E-02	-7.54E-02
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	5.25E-03	-6.70E-02	-2.40E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	6.74E-02	1.52E-01	7.77E-01
Colon cancer	2B90	Colon tissue	5.76E-16	1.12E-01	5.59E-01
Coronary artery disease	BA80-BA8Z	Peripheral blood	1.27E-01	-1.17E-01	-8.99E-01
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	9.46E-01	5.81E-02	2.80E-01
Endometriosis	GA10	Endometrium tissue	3.56E-02	9.66E-02	4.22E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	4.08E-01	-6.16E-02	-4.44E-01
Familial hypercholesterolemia	5C80.00	Whole blood	6.45E-02	-6.85E-02	-4.68E-01
Gastric cancer	2B72	Gastric tissue	4.15E-01	-5.43E-02	-3.75E-01
Glioblastopma	2A00.00	Nervous tissue	1.67E-75	-1.19E+00	-1.33E+00
Glioma	2A00.0Y-2A00.0Z	White matter tissue	1.71E-01	-1.25E+00	-7.20E-01
Head and neck cancer	2D42	Head and neck tissue	5.57E-05	-1.97E-01	-2.46E-01
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	4.79E-01	-2.11E-01	-3.37E-01
Huntington's disease	8A01.10	Whole blood	4.31E-01	-1.71E-02	-1.15E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	1.80E-04	1.17E+00	3.75E+00
Immunodeficiency	4A00-4A20	Peripheral blood	5.66E-01	-8.02E-03	-1.09E-01
Influenza	1.00E+30	Whole blood	5.89E-01	1.79E-02	3.49E-01
Interstitial cystitis	GC00.3	Bladder tissue	1.03E-02	6.93E-01	3.52E+00
Intracranial aneurysm	8B01.0	Intracranial artery	5.88E-02	1.11E+00	1.63E+00
Irritable bowel syndrome	DD91.0	Rectal colon tissue	8.49E-01	-1.02E-02	-2.61E-02
Ischemic stroke	8B11	Peripheral blood	5.10E-01	-1.37E-02	-8.62E-02
Juvenile idiopathic arthritis	FA24	Peripheral blood	4.22E-02	1.26E-02	8.69E-02
Lateral sclerosis	8B60.4	Cervical spinal cord	1.21E-01	-9.01E-01	-7.31E-01
Lateral sclerosis	8B60.4	Skin	2.20E-01	1.20E-01	5.68E-01
Liver cancer	2C12.0	Liver tissue	1.54E-05	-2.39E-01	-2.48E-01
Liver failure	DB99.7-DB99.8	Liver tissue	2.52E-09	-4.70E+00	-8.98E+00
Lung cancer	2C25	Lung tissue	5.79E-02	-1.72E-01	-3.66E-01
Lupus erythematosus	4A40	Whole blood	1.78E-02	-5.82E-02	-2.20E-01
Major depressive disorder	6A70-6A7Z	Whole blood	1.72E-01	1.56E-02	8.80E-02
Major depressive disorder	6A70-6A7Z	Hippocampus	5.31E-01	-3.03E-02	-1.38E-01
Melanoma	2C30	Skin	3.88E-01	-9.72E-02	-1.16E-01
Multiple myeloma	2A83.1	Bone marrow	4.99E-02	-2.37E-01	-6.24E-01
Multiple myeloma	2A83.1	Peripheral blood	5.23E-01	4.77E-02	5.53E-01
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	1.90E-01	1.03E-01	4.90E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	2.77E-01	-4.78E-02	-2.91E-01
Myelofibrosis	2A20.2	Whole blood	2.29E-02	1.44E-01	1.32E+00
Myocardial infarction	BA41-BA50	Peripheral blood	1.84E-01	5.31E-02	1.75E-01
Myopathy	8C70.6	Muscle tissue	1.37E-02	-6.10E-01	-1.71E+00
Neonatal sepsis	KA60	Whole blood	3.53E-01	4.24E-02	2.95E-01
Neuroectodermal tumour	2A00.11	Brain stem tissue	2.71E-16	-1.95E+00	-6.29E+00
Non-alcoholic fatty liver disease	DB92	Liver tissue	5.32E-01	1.03E-01	1.86E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	5.29E-01	4.92E-02	1.79E-01
Olive pollen allergy	CA08.00	Peripheral blood	7.01E-01	-2.94E-02	-3.16E-01
Oral cancer	2B6E	Oral tissue	6.97E-02	-1.94E-01	-2.85E-01
Osteoarthritis	FA00-FA0Z	Synovial tissue	8.56E-01	3.95E-01	5.49E-01
Osteoporosis	FB83.1	Bone marrow	4.92E-01	7.07E-02	9.54E-01
Ovarian cancer	2C73	Ovarian tissue	4.50E-01	-5.20E-02	-9.44E-02
Pancreatic cancer	2C10	Pancreas	7.61E-05	4.34E-01	1.18E+00
Parkinson's disease	8A00.0	Substantia nigra tissue	1.74E-02	-3.29E-01	-1.16E+00
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	2.19E-01	-6.15E-02	-4.83E-01
Pituitary cancer	2D12	Pituitary tissue	5.54E-01	1.51E-01	4.69E-01
Pituitary gonadotrope tumour	2D12	Pituitary tissue	9.23E-02	5.45E-01	1.34E+00
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	1.61E-01	-1.89E-03	-5.12E-03
Polycythemia vera	2A20.4	Whole blood	7.23E-05	6.76E-02	6.87E-01
Pompe disease	5C51.3	Biceps muscle	7.96E-03	-4.52E-01	-1.60E+00
Preterm birth	KA21.4Z	Myometrium	8.11E-01	4.44E-02	1.37E-01
Prostate cancer	2C82	Prostate	9.13E-01	3.58E-01	3.41E-01
Psoriasis	EA90	Skin	8.52E-18	4.01E-01	8.23E-01
Rectal cancer	2B92	Rectal colon tissue	1.81E-02	1.87E-01	9.20E-01
Renal cancer	2C90-2C91	Kidney	4.02E-04	4.96E-01	1.16E+00
Retinoblastoma	2D02.2	Uvea	9.74E-08	-5.10E+00	-1.55E+01
Rheumatoid arthritis	FA20	Synovial tissue	3.19E-01	-2.79E-01	-4.96E-01
Rhinovirus infection	CA42.1	Nasal epithelium tissue	4.25E-01	-3.77E-02	-3.40E-01
Schizophrenia	6A20	Prefrontal cortex	9.75E-02	-1.80E-01	-5.84E-02
Schizophrenia	6A20	Superior temporal cortex	2.19E-01	-7.27E-02	-3.24E-01
Scleroderma	4A42.Z	Whole blood	8.46E-01	2.13E-02	1.24E-01
Seizure	8A60-8A6Z	Whole blood	3.56E-01	-7.83E-02	-4.06E-01
Sensitive skin	EK0Z	Skin	1.70E-01	-5.64E-03	-5.00E-02
Sepsis with septic shock	1G41	Whole blood	8.41E-03	7.60E-02	4.35E-01
Shwachman-Diamond syndrome	3A70.0	Bone marrow	1.39E-01	1.28E-01	1.04E+00
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	6.65E-01	4.92E-02	4.23E-01
Simpson golabi behmel syndrome	LD2C	Adipose tissue	2.46E-01	5.93E-02	3.08E+00
Sjogren's syndrome	4A43.2	Salivary gland tissue	5.66E-01	-6.30E-02	-6.36E-01
Skin cancer	2C30-2C3Z	Skin	5.91E-06	2.00E-01	3.86E-01
Thrombocythemia	3B63	Whole blood	2.38E-03	1.89E-01	1.75E+00
Thrombocytopenia	3B64	Whole blood	5.63E-01	4.98E-02	1.83E-01
Thyroid cancer	2D10	Thyroid	1.04E-17	5.12E-01	9.38E-01
Tibial muscular dystrophy	8C75	Muscle tissue	1.02E-01	1.83E-01	3.96E-01
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	2.30E-01	-4.12E-01	-3.85E+00
Type 2 diabetes	5A11	Liver tissue	6.65E-01	2.07E-01	5.99E-01
Ureter cancer	2C92	Urothelium	8.80E-02	-7.98E-02	-4.98E-01
Uterine cancer	2C78	Endometrium tissue	8.33E-03	1.55E-01	2.93E-01
Vitiligo	ED63.0	Skin	1.91E-01	-5.85E-01	-7.21E-01