Details of the Drug-Related molecule(s) Expression Atlas

General Information of DTP (ID: DT9NXMV)

• DTP Name: ATP-binding cassette sub-family A member 8 (ABCA8) DTP Info
• Gene Name: ABCA8

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	2.01E-03	4.91E-02	3.00E-01
Adrenocortical carcinoma	2D11.Z	Kidney	6.46E-01	-8.28E-02	-1.37E-01
Alopecia	ED70	Skin from scalp	8.81E-01	1.15E-02	4.08E-02
Alzheimer's disease	8A20	Entorhinal cortex	3.65E-02	2.10E-01	3.12E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	6.07E-01	3.88E-02	4.35E-01
Aortic stenosis	BB70	Calcified aortic valve	6.40E-01	-3.01E-02	-3.65E-02
Apnea	7A40	Hyperplastic tonsil	3.70E-01	-4.24E-02	-2.22E-01
Arthropathy	FA00-FA5Z	Peripheral blood	8.27E-01	2.90E-02	3.10E-01
Asthma	CA23	Nasal and bronchial airway	2.37E-03	-1.07E-01	-3.79E-01
Atopic dermatitis	EA80	Skin	2.43E-10	-5.48E-01	-1.72E+00
Autism	6A02	Whole blood	8.30E-02	8.78E-02	5.74E-01
Autoimmune uveitis	9A96	Peripheral monocyte	6.79E-01	-9.65E-02	-5.27E-01
Autosomal dominant monocytopenia	4B04	Whole blood	2.59E-01	-2.57E-02	-2.04E-01
Bacterial infection of gingival	1C1H	Gingival tissue	7.31E-01	1.22E-03	6.76E-03
Batten disease	5C56.1	Whole blood	4.49E-01	1.28E-01	1.01E+00
Behcet's disease	4A62	Peripheral blood	9.74E-01	-4.50E-02	-3.00E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	6.61E-01	4.72E-02	1.48E-01
Bladder cancer	2C94	Bladder tissue	8.03E-02	-2.09E-01	-5.66E-01
Breast cancer	2C60-2C6Z	Breast tissue	2.06E-72	-5.62E-01	-1.43E+00
Cardioembolic stroke	8B11.20	Whole blood	1.75E-01	6.52E-02	4.47E-01
Cervical cancer	2C77	Cervical tissue	6.16E-02	-7.69E-02	-4.43E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	7.82E-01	-2.92E-03	-1.16E-02
Chronic hepatitis C	1E51.1	Whole blood	9.77E-01	-1.14E-01	-4.35E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	4.70E-01	-1.61E-02	-4.36E-02
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	8.29E-01	1.98E-02	1.47E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	9.68E-01	5.41E-02	2.40E-01
Colon cancer	2B90	Colon tissue	4.26E-56	-5.06E-01	-1.85E+00
Coronary artery disease	BA80-BA8Z	Peripheral blood	3.42E-01	-8.22E-02	-5.44E-01
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	7.44E-01	5.82E-02	3.13E-01
Endometriosis	GA10	Endometrium tissue	1.13E-03	1.84E-01	5.35E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	7.17E-01	-4.75E-02	-2.87E-01
Familial hypercholesterolemia	5C80.00	Whole blood	4.10E-07	-2.65E-01	-1.44E+00
Gastric cancer	2B72	Gastric tissue	1.10E-01	-1.06E+00	-2.14E+00
Glioblastopma	2A00.00	Nervous tissue	4.25E-49	-6.46E-01	-7.46E-01
Glioma	2A00.0Y-2A00.0Z	White matter tissue	4.16E-04	-5.47E-01	-1.61E+00
Head and neck cancer	2D42	Head and neck tissue	6.18E-02	-4.67E-02	-9.50E-02
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	9.68E-01	9.68E-02	7.49E-02
Huntington's disease	8A01.10	Whole blood	1.28E-01	9.59E-02	8.66E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	5.29E-01	-4.08E-01	-1.32E+00
Immunodeficiency	4A00-4A20	Peripheral blood	8.18E-02	6.30E-02	6.65E-01
Influenza	1.00E+30	Whole blood	1.38E-01	3.37E-01	2.93E+00
Interstitial cystitis	GC00.3	Bladder tissue	2.31E-01	-1.92E-01	-2.13E+00
Intracranial aneurysm	8B01.0	Intracranial artery	7.65E-02	-6.09E-01	-6.13E-01
Irritable bowel syndrome	DD91.0	Rectal colon tissue	2.76E-01	8.98E-02	2.27E-01
Ischemic stroke	8B11	Peripheral blood	3.76E-01	-1.57E-02	-1.23E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	6.33E-02	8.51E-02	3.80E-01
Lateral sclerosis	8B60.4	Cervical spinal cord	9.97E-01	6.50E-02	2.71E-01
Lateral sclerosis	8B60.4	Skin	6.55E-01	-1.18E-01	-1.00E+00
Liver cancer	2C12.0	Liver tissue	1.39E-05	-6.51E-01	-5.68E-01
Liver failure	DB99.7-DB99.8	Liver tissue	2.14E-05	-1.38E+00	-3.20E+00
Lung cancer	2C25	Lung tissue	3.27E-30	-2.62E-01	-9.68E-01
Lupus erythematosus	4A40	Whole blood	7.56E-01	1.92E-02	8.08E-02
Major depressive disorder	6A70-6A7Z	Whole blood	2.36E-01	7.13E-02	3.03E-01
Major depressive disorder	6A70-6A7Z	Hippocampus	2.36E-01	-6.40E-02	-1.86E-01
Melanoma	2C30	Skin	6.76E-01	-1.33E-01	-3.60E-01
Multiple myeloma	2A83.1	Bone marrow	5.68E-02	8.49E-02	7.28E-01
Multiple myeloma	2A83.1	Peripheral blood	7.32E-01	-4.85E-03	-3.10E-02
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	7.94E-01	4.11E-03	1.35E-02
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	7.29E-01	-2.30E-03	-1.57E-02
Myelofibrosis	2A20.2	Whole blood	2.10E-03	-1.99E-01	-1.42E+00
Myocardial infarction	BA41-BA50	Peripheral blood	1.21E-01	2.47E-02	6.81E-02
Myopathy	8C70.6	Muscle tissue	9.46E-01	-9.15E-02	-2.99E-01
Neonatal sepsis	KA60	Whole blood	7.22E-01	3.81E-02	2.47E-01
Neuroectodermal tumour	2A00.11	Brain stem tissue	1.15E-07	-1.08E+00	-4.44E+00
Non-alcoholic fatty liver disease	DB92	Liver tissue	9.31E-01	-2.19E-02	-1.01E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	2.20E-01	-5.76E-02	-1.25E-01
Olive pollen allergy	CA08.00	Peripheral blood	1.75E-01	1.35E-01	2.21E+00
Oral cancer	2B6E	Oral tissue	1.18E-05	-4.12E-01	-1.14E+00
Osteoarthritis	FA00-FA0Z	Synovial tissue	5.78E-01	1.54E-02	5.80E-02
Osteoporosis	FB83.1	Bone marrow	1.58E-01	9.21E-02	4.72E-01
Ovarian cancer	2C73	Ovarian tissue	3.46E-03	-9.97E-01	-1.21E+00
Pancreatic cancer	2C10	Pancreas	7.65E-03	-3.47E-01	-8.98E-01
Parkinson's disease	8A00.0	Substantia nigra tissue	7.52E-01	8.14E-02	1.22E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	2.62E-04	-1.61E-01	-2.00E+00
Pituitary cancer	2D12	Pituitary tissue	4.95E-04	-9.52E-01	-1.63E+00
Pituitary gonadotrope tumour	2D12	Pituitary tissue	1.03E-03	-1.01E+00	-1.59E+00
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	5.87E-01	3.59E-02	3.39E-01
Polycythemia vera	2A20.4	Whole blood	1.09E-06	-1.65E-01	-1.32E+00
Pompe disease	5C51.3	Biceps muscle	3.62E-01	-5.33E-02	-5.81E-01
Preterm birth	KA21.4Z	Myometrium	1.35E-01	-5.64E-02	-7.07E-01
Prostate cancer	2C82	Prostate	8.02E-03	-2.98E-01	-7.27E-01
Psoriasis	EA90	Skin	4.28E-04	-2.40E-01	-5.23E-01
Rectal cancer	2B92	Rectal colon tissue	8.24E-04	-5.74E-01	-2.08E+00
Renal cancer	2C90-2C91	Kidney	9.46E-04	-2.99E-01	-1.22E+00
Retinoblastoma	2D02.2	Uvea	2.65E-03	1.42E+00	1.23E+01
Rheumatoid arthritis	FA20	Synovial tissue	5.12E-01	-4.83E-02	-1.91E-01
Rhinovirus infection	CA42.1	Nasal epithelium tissue	9.00E-01	8.62E-03	6.62E-02
Schizophrenia	6A20	Prefrontal cortex	2.23E-01	-2.69E-02	-4.77E-02
Schizophrenia	6A20	Superior temporal cortex	2.68E-01	-1.14E-02	-4.00E-02
Scleroderma	4A42.Z	Whole blood	4.02E-02	1.41E-01	1.07E+00
Seizure	8A60-8A6Z	Whole blood	9.01E-01	-6.13E-02	-2.72E-01
Sensitive skin	EK0Z	Skin	3.56E-01	8.37E-02	3.53E-01
Sepsis with septic shock	1G41	Whole blood	2.59E-06	9.59E-02	4.92E-01
Shwachman-Diamond syndrome	3A70.0	Bone marrow	2.71E-01	8.13E-02	3.26E-01
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	2.27E-01	2.19E-02	1.54E-01
Simpson golabi behmel syndrome	LD2C	Adipose tissue	7.62E-01	-6.75E-02	-2.85E-01
Sjogren's syndrome	4A43.2	Salivary gland tissue	1.28E-01	-2.84E-02	-5.86E-01
Skin cancer	2C30-2C3Z	Skin	1.69E-15	-3.88E-01	-9.46E-01
Thrombocythemia	3B63	Whole blood	1.05E-06	-1.70E-01	-1.25E+00
Thrombocytopenia	3B64	Whole blood	4.36E-01	-3.06E-02	-1.13E-01
Thyroid cancer	2D10	Thyroid	4.29E-01	-3.90E-02	-1.49E-01
Tibial muscular dystrophy	8C75	Muscle tissue	6.91E-02	-2.31E-01	-5.55E-01
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	4.01E-01	1.84E-01	6.03E-01
Type 2 diabetes	5A11	Liver tissue	3.75E-01	-2.33E-01	-4.33E-01
Ureter cancer	2C92	Urothelium	5.71E-01	-3.50E-02	-1.65E-01
Uterine cancer	2C78	Endometrium tissue	1.03E-12	-2.03E-01	-6.14E-01
Vitiligo	ED63.0	Skin	1.35E-01	3.94E-01	1.03E+00