Details of the Drug-Related molecule(s) Expression Atlas

General Information of DTP (ID: DTAV4SY)

• DTP Name: Sodium-dependent serotonin transporter (SLC6A4) DTP Info
• Gene Name: SERT

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	1.09E-02	-7.21E-02	-4.64E-01
Adrenocortical carcinoma	2D11.Z	Kidney	7.25E-01	8.85E-03	7.34E-02
Alopecia	ED70	Skin from scalp	1.34E-03	2.17E-01	6.03E-01
Alzheimer's disease	8A20	Entorhinal cortex	4.85E-01	-5.68E-03	-6.27E-02
Ankylosing spondylitis	FA92.0	Pheripheral blood	2.25E-01	2.78E-02	2.73E-01
Aortic stenosis	BB70	Calcified aortic valve	4.05E-01	-2.73E-01	-4.91E-01
Apnea	7A40	Hyperplastic tonsil	6.70E-01	4.57E-01	1.09E+00
Arthropathy	FA00-FA5Z	Peripheral blood	8.68E-02	6.01E-02	3.73E-01
Asthma	CA23	Nasal and bronchial airway	4.04E-01	4.35E-02	1.44E-01
Atopic dermatitis	EA80	Skin	1.97E-03	1.78E-01	1.75E+00
Autism	6A02	Whole blood	2.52E-01	6.90E-02	3.48E-01
Autoimmune uveitis	9A96	Peripheral monocyte	5.51E-01	4.64E-02	3.98E-01
Autosomal dominant monocytopenia	4B04	Whole blood	7.29E-01	7.10E-02	4.54E-01
Bacterial infection of gingival	1C1H	Gingival tissue	1.30E-14	-7.21E-01	-1.41E+00
Batten disease	5C56.1	Whole blood	9.11E-01	4.64E-02	6.14E-02
Behcet's disease	4A62	Peripheral blood	6.73E-01	2.09E-04	1.08E-03
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	1.34E-01	2.48E-02	2.17E-01
Bladder cancer	2C94	Bladder tissue	5.97E-01	1.26E-03	1.35E-02
Breast cancer	2C60-2C6Z	Breast tissue	2.85E-34	7.25E-02	2.52E-01
Cardioembolic stroke	8B11.20	Whole blood	8.73E-01	5.44E-02	1.10E-01
Cervical cancer	2C77	Cervical tissue	5.26E-03	-7.41E-01	-9.36E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	1.78E-01	3.16E-02	1.71E-01
Chronic hepatitis C	1E51.1	Whole blood	5.78E-01	9.84E-02	7.25E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	9.46E-01	2.06E-01	1.19E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	5.63E-01	8.42E-03	1.75E-02
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	1.91E-01	7.49E-02	1.05E+00
Colon cancer	2B90	Colon tissue	5.64E-06	7.92E-02	1.38E-01
Coronary artery disease	BA80-BA8Z	Peripheral blood	7.61E-02	-2.48E-01	-1.73E+00
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	3.76E-01	-1.81E-01	-7.68E-01
Endometriosis	GA10	Endometrium tissue	9.72E-01	-3.97E-02	-2.81E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	6.17E-01	-1.23E-02	-1.54E-01
Familial hypercholesterolemia	5C80.00	Whole blood	1.59E-01	2.62E-01	7.91E-01
Gastric cancer	2B72	Gastric tissue	4.86E-01	2.96E-02	1.60E-01
Glioblastopma	2A00.00	Nervous tissue	8.93E-01	-8.72E-03	-1.73E-02
Glioma	2A00.0Y-2A00.0Z	White matter tissue	8.84E-01	-5.67E-02	-2.44E-01
Head and neck cancer	2D42	Head and neck tissue	3.13E-11	-5.23E-01	-4.63E-01
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	1.26E-02	-7.58E-02	-9.49E-01
Huntington's disease	8A01.10	Whole blood	2.23E-01	7.49E-02	6.36E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	7.84E-02	-1.48E+00	-1.45E+00
Immunodeficiency	4A00-4A20	Peripheral blood	8.73E-01	-2.42E-02	-4.47E-01
Influenza	1.00E+30	Whole blood	1.02E-02	2.71E-01	6.23E+00
Interstitial cystitis	GC00.3	Bladder tissue	6.48E-01	-1.17E-02	-9.23E-02
Intracranial aneurysm	8B01.0	Intracranial artery	1.09E-01	-1.46E-03	-1.09E-02
Irritable bowel syndrome	DD91.0	Rectal colon tissue	2.74E-01	5.69E-02	2.12E-01
Ischemic stroke	8B11	Peripheral blood	4.21E-01	7.84E-02	3.00E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	8.84E-05	1.66E-01	6.44E-01
Lateral sclerosis	8B60.4	Cervical spinal cord	4.01E-02	1.71E-01	1.35E+00
Lateral sclerosis	8B60.4	Skin	5.93E-01	-1.31E-02	-1.40E-01
Liver cancer	2C12.0	Liver tissue	3.38E-05	-4.63E-02	-3.45E-01
Liver failure	DB99.7-DB99.8	Liver tissue	2.29E-01	1.79E-02	1.89E-01
Lung cancer	2C25	Lung tissue	3.41E-80	-5.03E+00	-2.90E+00
Lupus erythematosus	4A40	Whole blood	8.27E-01	2.07E-02	4.34E-02
Major depressive disorder	6A70-6A7Z	Whole blood	1.20E-02	9.16E-02	3.52E-01
Major depressive disorder	6A70-6A7Z	Hippocampus	1.17E-01	6.87E-02	5.88E-01
Melanoma	2C30	Skin	5.88E-03	-4.75E-01	-6.70E-01
Multiple myeloma	2A83.1	Bone marrow	2.67E-02	-2.53E-01	-8.23E-01
Multiple myeloma	2A83.1	Peripheral blood	8.13E-01	1.05E-02	7.31E-02
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	2.81E-02	-2.78E-01	-1.13E+00
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	1.52E-01	-2.37E-02	-1.26E-01
Myelofibrosis	2A20.2	Whole blood	5.40E-02	6.32E-02	6.35E-01
Myocardial infarction	BA41-BA50	Peripheral blood	1.33E-01	1.82E-01	3.19E-01
Myopathy	8C70.6	Muscle tissue	8.49E-01	3.13E-02	3.57E-01
Neonatal sepsis	KA60	Whole blood	7.74E-01	-3.29E-03	-2.20E-02
Neuroectodermal tumour	2A00.11	Brain stem tissue	2.20E-05	8.79E-02	1.13E+00
Non-alcoholic fatty liver disease	DB92	Liver tissue	8.12E-01	1.33E-03	1.25E-02
Obesity related type 2 diabetes	5A11	Omental adipose tissue	8.91E-01	-9.00E-02	-3.35E-01
Olive pollen allergy	CA08.00	Peripheral blood	7.35E-01	-1.99E-01	-5.97E-01
Oral cancer	2B6E	Oral tissue	1.27E-02	-7.88E-01	-1.10E+00
Osteoarthritis	FA00-FA0Z	Synovial tissue	2.00E-01	-1.12E-01	-4.95E-01
Osteoporosis	FB83.1	Bone marrow	5.29E-02	1.91E-01	2.23E+00
Ovarian cancer	2C73	Ovarian tissue	3.03E-01	-1.72E-01	-3.18E-01
Pancreatic cancer	2C10	Pancreas	1.81E-01	-6.56E-02	-2.22E-01
Parkinson's disease	8A00.0	Substantia nigra tissue	8.76E-01	7.18E-05	6.19E-04
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	9.00E-01	-7.57E-02	-4.35E-01
Pituitary cancer	2D12	Pituitary tissue	1.21E-03	9.66E-02	1.00E+00
Pituitary gonadotrope tumour	2D12	Pituitary tissue	2.73E-01	6.41E-02	6.93E-01
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	4.06E-01	3.19E-03	4.85E-02
Polycythemia vera	2A20.4	Whole blood	6.90E-03	5.61E-02	5.45E-01
Pompe disease	5C51.3	Biceps muscle	8.76E-01	6.17E-02	8.10E-01
Preterm birth	KA21.4Z	Myometrium	5.69E-01	-1.21E-01	-1.01E+00
Prostate cancer	2C82	Prostate	1.46E-03	1.31E-01	6.45E-01
Psoriasis	EA90	Skin	1.30E-11	-2.73E-01	-6.78E-01
Rectal cancer	2B92	Rectal colon tissue	4.54E-01	-5.16E-02	-2.43E-01
Renal cancer	2C90-2C91	Kidney	9.00E-01	-1.31E-01	-9.05E-01
Retinoblastoma	2D02.2	Uvea	3.84E-01	3.60E-02	4.59E-01
Rheumatoid arthritis	FA20	Synovial tissue	3.06E-02	-4.08E-01	-1.29E+00
Rhinovirus infection	CA42.1	Nasal epithelium tissue	9.86E-01	6.57E-03	9.39E-02
Schizophrenia	6A20	Prefrontal cortex	7.90E-01	3.80E-02	1.42E-01
Schizophrenia	6A20	Superior temporal cortex	4.98E-01	4.47E-02	7.03E-01
Scleroderma	4A42.Z	Whole blood	1.45E-01	1.65E-01	7.73E-01
Seizure	8A60-8A6Z	Whole blood	1.36E-01	-6.73E-02	-3.54E-01
Sensitive skin	EK0Z	Skin	4.72E-01	-1.43E-02	-1.26E-01
Sepsis with septic shock	1G41	Whole blood	1.99E-01	4.61E-02	2.32E-01
Shwachman-Diamond syndrome	3A70.0	Bone marrow	5.83E-01	-8.31E-02	-4.19E-01
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	2.20E-01	-4.42E-01	-7.81E-01
Simpson golabi behmel syndrome	LD2C	Adipose tissue	8.57E-01	3.86E-02	3.36E-01
Sjogren's syndrome	4A43.2	Salivary gland tissue	4.52E-01	-3.66E-02	-3.77E-01
Skin cancer	2C30-2C3Z	Skin	2.03E-37	-5.58E-01	-1.27E+00
Thrombocythemia	3B63	Whole blood	9.31E-01	-2.39E-02	-2.50E-01
Thrombocytopenia	3B64	Whole blood	6.29E-01	-8.46E-03	-6.03E-02
Thyroid cancer	2D10	Thyroid	3.80E-03	-1.03E-01	-3.52E-01
Tibial muscular dystrophy	8C75	Muscle tissue	1.05E-03	-2.00E-01	-1.29E+00
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	3.06E-01	5.41E-02	5.49E-01
Type 2 diabetes	5A11	Liver tissue	3.77E-01	9.22E-02	7.78E-01
Ureter cancer	2C92	Urothelium	7.16E-02	1.49E-01	9.28E-01
Uterine cancer	2C78	Endometrium tissue	3.88E-01	2.45E-02	6.09E-02
Vitiligo	ED63.0	Skin	6.37E-01	3.57E-02	2.69E-01