Details of the Drug-Related molecule(s) Expression Atlas

General Information of DTP (ID: DTC54PX)

• DTP Name: Alanine/serine/cysteine/threonine transporter 1 (SLC1A4) DTP Info
• Gene Name: ASCT1

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	5.94E-02	-1.66E-01	-3.80E-01
Adrenocortical carcinoma	2D11.Z	Kidney	1.24E-05	-5.30E-01	-1.27E+00
Alopecia	ED70	Skin from scalp	2.11E-02	-1.72E-01	-6.35E-01
Alzheimer's disease	8A20	Entorhinal cortex	2.73E-01	-1.32E-01	-3.19E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	4.76E-02	2.38E-01	7.80E-01
Aortic stenosis	BB70	Calcified aortic valve	9.96E-01	-7.80E-02	-8.52E-02
Apnea	7A40	Hyperplastic tonsil	1.31E-01	-4.40E-01	-6.81E-01
Arthropathy	FA00-FA5Z	Peripheral blood	4.45E-01	3.20E-02	2.07E-01
Asthma	CA23	Nasal and bronchial airway	6.04E-01	5.51E-02	1.15E-01
Atopic dermatitis	EA80	Skin	3.48E-03	2.13E-01	1.32E+00
Autism	6A02	Whole blood	6.05E-01	3.93E-02	9.04E-02
Autoimmune uveitis	9A96	Peripheral monocyte	3.44E-01	-2.34E-01	-5.51E-01
Autosomal dominant monocytopenia	4B04	Whole blood	7.72E-01	1.85E-01	3.25E-01
Bacterial infection of gingival	1C1H	Gingival tissue	3.28E-11	4.20E-01	1.15E+00
Batten disease	5C56.1	Whole blood	5.69E-01	-1.78E-01	-5.35E-01
Behcet's disease	4A62	Peripheral blood	8.14E-01	1.24E-02	3.15E-02
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	8.79E-02	6.38E-02	2.19E-01
Bladder cancer	2C94	Bladder tissue	2.76E-02	3.74E-01	1.09E+00
Breast cancer	2C60-2C6Z	Breast tissue	6.61E-34	6.79E-01	9.19E-01
Cardioembolic stroke	8B11.20	Whole blood	8.58E-01	1.91E-02	5.70E-02
Cervical cancer	2C77	Cervical tissue	2.14E-02	-6.27E-01	-8.92E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	3.37E-01	-8.80E-03	-2.72E-02
Chronic hepatitis C	1E51.1	Whole blood	9.37E-01	-2.73E-02	-5.03E-02
Chronic obstructive pulmonary disease	CA22	Lung tissue	2.68E-01	-6.19E-02	-1.36E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	5.58E-02	1.05E-01	2.93E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	1.77E-03	-5.85E-01	-1.60E+00
Colon cancer	2B90	Colon tissue	3.49E-42	5.81E-01	1.47E+00
Coronary artery disease	BA80-BA8Z	Peripheral blood	1.85E-02	5.59E-01	4.53E+00
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	7.27E-01	-1.27E-01	-2.14E-01
Endometriosis	GA10	Endometrium tissue	2.23E-01	-6.20E-01	-7.47E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	8.27E-01	-9.08E-02	-5.47E-01
Familial hypercholesterolemia	5C80.00	Whole blood	3.41E-04	6.85E-01	2.14E+00
Gastric cancer	2B72	Gastric tissue	8.31E-01	-2.31E-01	-3.83E-01
Glioblastopma	2A00.00	Nervous tissue	5.13E-07	-2.76E-01	-4.85E-01
Glioma	2A00.0Y-2A00.0Z	White matter tissue	6.61E-01	-1.27E-02	-3.00E-02
Head and neck cancer	2D42	Head and neck tissue	2.03E-06	2.95E-01	7.39E-01
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	1.20E-01	1.51E-01	3.40E-01
Huntington's disease	8A01.10	Whole blood	1.82E-01	-1.21E-01	-5.28E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	1.24E-01	3.04E-01	7.96E-01
Immunodeficiency	4A00-4A20	Peripheral blood	6.16E-03	5.41E-01	1.73E+00
Influenza	1.00E+30	Whole blood	2.53E-01	-9.22E-02	-8.14E-01
Interstitial cystitis	GC00.3	Bladder tissue	6.31E-05	1.50E+00	4.45E+00
Intracranial aneurysm	8B01.0	Intracranial artery	8.45E-01	-1.40E-01	-2.73E-01
Irritable bowel syndrome	DD91.0	Rectal colon tissue	3.06E-01	-8.24E-02	-2.44E-01
Ischemic stroke	8B11	Peripheral blood	5.59E-01	-6.30E-02	-2.65E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	6.61E-01	-3.63E-02	-7.46E-02
Lateral sclerosis	8B60.4	Cervical spinal cord	5.40E-01	8.03E-02	1.26E-01
Lateral sclerosis	8B60.4	Skin	6.77E-01	-2.34E-01	-2.79E-01
Liver cancer	2C12.0	Liver tissue	7.32E-04	1.11E+00	1.04E+00
Liver failure	DB99.7-DB99.8	Liver tissue	6.24E-01	6.68E-02	8.74E-02
Lung cancer	2C25	Lung tissue	9.32E-77	1.11E+00	2.30E+00
Lupus erythematosus	4A40	Whole blood	1.02E-01	7.61E-02	1.36E-01
Major depressive disorder	6A70-6A7Z	Whole blood	7.69E-01	4.16E-02	1.34E-01
Major depressive disorder	6A70-6A7Z	Hippocampus	5.47E-02	-9.78E-02	-3.58E-01
Melanoma	2C30	Skin	6.37E-01	2.27E-02	2.72E-02
Multiple myeloma	2A83.1	Bone marrow	1.05E-05	1.20E+00	3.79E+00
Multiple myeloma	2A83.1	Peripheral blood	5.47E-01	-2.21E-01	-1.66E-01
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	3.44E-01	1.94E-01	3.02E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	6.22E-08	-3.66E-01	-1.23E+00
Myelofibrosis	2A20.2	Whole blood	1.75E-05	4.59E-01	2.10E+00
Myocardial infarction	BA41-BA50	Peripheral blood	9.40E-01	-9.54E-02	-1.07E-01
Myopathy	8C70.6	Muscle tissue	4.66E-02	-5.77E-01	-1.31E+00
Neonatal sepsis	KA60	Whole blood	4.99E-01	9.61E-03	2.78E-02
Neuroectodermal tumour	2A00.11	Brain stem tissue	4.52E-02	2.99E-01	6.94E-01
Non-alcoholic fatty liver disease	DB92	Liver tissue	4.64E-01	-1.18E-01	-4.06E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	5.32E-01	4.63E-02	3.18E-01
Olive pollen allergy	CA08.00	Peripheral blood	7.11E-01	-3.64E-01	-4.04E-01
Oral cancer	2B6E	Oral tissue	2.39E-02	4.28E-01	4.42E-01
Osteoarthritis	FA00-FA0Z	Synovial tissue	8.09E-01	1.20E-01	2.55E-01
Osteoporosis	FB83.1	Bone marrow	1.19E-01	4.94E-01	1.44E+00
Ovarian cancer	2C73	Ovarian tissue	1.38E-01	-4.99E-01	-1.03E+00
Pancreatic cancer	2C10	Pancreas	2.87E-03	-6.70E-01	-1.01E+00
Parkinson's disease	8A00.0	Substantia nigra tissue	5.71E-01	-2.07E-01	-4.63E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	3.78E-02	9.48E-02	3.66E-01
Pituitary cancer	2D12	Pituitary tissue	8.67E-02	2.61E-01	6.86E-01
Pituitary gonadotrope tumour	2D12	Pituitary tissue	7.66E-01	-4.72E-04	-1.07E-03
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	2.56E-01	1.08E-01	3.04E-01
Polycythemia vera	2A20.4	Whole blood	7.29E-02	6.18E-02	3.81E-01
Pompe disease	5C51.3	Biceps muscle	6.19E-01	7.90E-04	8.23E-04
Preterm birth	KA21.4Z	Myometrium	5.74E-01	3.48E-02	9.00E-02
Prostate cancer	2C82	Prostate	2.58E-06	1.08E+00	1.47E+00
Psoriasis	EA90	Skin	7.35E-19	4.03E-01	1.06E+00
Rectal cancer	2B92	Rectal colon tissue	7.02E-02	1.89E-01	5.96E-01
Renal cancer	2C90-2C91	Kidney	1.05E-06	1.10E+00	3.35E+00
Retinoblastoma	2D02.2	Uvea	4.23E-01	2.19E-01	6.51E-01
Rheumatoid arthritis	FA20	Synovial tissue	2.93E-02	-7.62E-01	-1.84E+00
Rhinovirus infection	CA42.1	Nasal epithelium tissue	9.27E-01	-7.52E-02	-2.40E-01
Schizophrenia	6A20	Prefrontal cortex	3.33E-01	-1.01E-01	-1.26E-01
Schizophrenia	6A20	Superior temporal cortex	1.93E-01	1.65E-01	5.95E-01
Scleroderma	4A42.Z	Whole blood	2.66E-05	3.12E-01	1.78E+00
Seizure	8A60-8A6Z	Whole blood	7.20E-01	4.87E-02	8.62E-02
Sensitive skin	EK0Z	Skin	7.65E-01	-1.54E-01	-5.89E-01
Sepsis with septic shock	1G41	Whole blood	3.24E-02	6.64E-02	1.91E-01
Shwachman-Diamond syndrome	3A70.0	Bone marrow	2.46E-01	-1.90E-01	-1.22E+00
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	2.43E-02	-1.24E-01	-7.36E-01
Simpson golabi behmel syndrome	LD2C	Adipose tissue	4.28E-01	1.02E+00	1.09E+00
Sjogren's syndrome	4A43.2	Salivary gland tissue	1.38E-01	4.43E-01	1.63E+00
Skin cancer	2C30-2C3Z	Skin	2.46E-14	6.40E-01	1.09E+00
Thrombocythemia	3B63	Whole blood	1.27E-04	2.19E-01	1.25E+00
Thrombocytopenia	3B64	Whole blood	8.07E-01	-1.65E-01	-2.15E-01
Thyroid cancer	2D10	Thyroid	4.28E-07	6.26E-01	8.71E-01
Tibial muscular dystrophy	8C75	Muscle tissue	7.29E-04	-6.81E-01	-9.92E-01
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	6.92E-01	-3.13E-01	-8.10E-01
Type 2 diabetes	5A11	Liver tissue	1.35E-01	1.81E-01	1.02E+00
Ureter cancer	2C92	Urothelium	2.20E-01	1.38E-01	5.68E-01
Uterine cancer	2C78	Endometrium tissue	4.19E-09	-5.93E-01	-7.86E-01
Vitiligo	ED63.0	Skin	2.26E-03	-2.92E-01	-1.35E+00