Details of the Drug-Related molecule(s) Expression Atlas

General Information of DTP (ID: DTCSGPB)

• DTP Name: Multidrug resistance-associated protein 4 (ABCC4) DTP Info
• Gene Name: MRP4

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	4.44E-03	1.29E-01	2.96E-01
Adrenocortical carcinoma	2D11.Z	Kidney	3.28E-04	1.29E-01	1.01E+00
Alopecia	ED70	Skin from scalp	4.79E-03	5.95E-02	2.61E-01
Alzheimer's disease	8A20	Entorhinal cortex	3.73E-06	2.82E-01	7.01E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	1.89E-01	4.27E-01	8.89E-01
Aortic stenosis	BB70	Calcified aortic valve	8.92E-01	7.89E-02	1.65E-01
Apnea	7A40	Hyperplastic tonsil	4.64E-01	-1.07E-01	-7.84E-01
Arthropathy	FA00-FA5Z	Peripheral blood	1.30E-02	3.52E-01	8.22E-01
Asthma	CA23	Nasal and bronchial airway	6.01E-05	-4.10E-01	-3.86E-01
Atopic dermatitis	EA80	Skin	2.32E-03	7.78E-02	5.58E-01
Autism	6A02	Whole blood	6.20E-01	2.01E-02	3.88E-02
Autoimmune uveitis	9A96	Peripheral monocyte	2.92E-01	1.31E-01	5.28E-01
Autosomal dominant monocytopenia	4B04	Whole blood	1.24E-01	2.71E-01	1.14E+00
Bacterial infection of gingival	1C1H	Gingival tissue	3.99E-01	4.49E-02	1.30E-01
Batten disease	5C56.1	Whole blood	1.61E-01	-4.86E-01	-4.95E-01
Behcet's disease	4A62	Peripheral blood	9.32E-01	3.07E-03	6.77E-03
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	7.79E-01	-3.49E-04	-2.76E-03
Bladder cancer	2C94	Bladder tissue	3.77E-06	-3.12E+00	-5.55E+00
Breast cancer	2C60-2C6Z	Breast tissue	6.84E-05	8.79E-02	1.77E-01
Cardioembolic stroke	8B11.20	Whole blood	3.35E-01	1.12E-01	1.97E-01
Cervical cancer	2C77	Cervical tissue	8.85E-01	1.43E-02	6.54E-02
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	1.29E-02	4.24E-01	6.28E-01
Chronic hepatitis C	1E51.1	Whole blood	5.32E-01	-5.83E-02	-3.32E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	7.64E-01	-9.15E-02	-1.85E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	1.09E-09	-6.55E-01	-1.03E+00
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	3.17E-01	7.72E-02	4.63E-01
Colon cancer	2B90	Colon tissue	3.99E-04	-4.42E-01	-6.80E-01
Coronary artery disease	BA80-BA8Z	Peripheral blood	5.62E-01	-1.57E-01	-8.51E-01
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	9.01E-01	5.23E-03	2.31E-02
Endometriosis	GA10	Endometrium tissue	3.78E-01	-2.23E-02	-1.90E-02
Familial hypercholesterolemia	5C80.00	Peripheral blood	1.45E-01	-1.84E-01	-7.08E-01
Familial hypercholesterolemia	5C80.00	Whole blood	1.52E-01	4.56E-01	8.84E-01
Gastric cancer	2B72	Gastric tissue	3.31E-03	7.37E-01	4.41E+00
Glioblastopma	2A00.00	Nervous tissue	1.17E-20	2.12E-01	5.35E-01
Glioma	2A00.0Y-2A00.0Z	White matter tissue	9.78E-01	2.37E-01	2.99E-01
Head and neck cancer	2D42	Head and neck tissue	4.80E-02	-2.04E-02	-2.13E-02
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	4.29E-01	4.07E-03	1.82E-02
Huntington's disease	8A01.10	Whole blood	4.70E-01	1.37E-02	7.16E-02
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	2.79E-03	-9.72E-01	-2.65E+00
Immunodeficiency	4A00-4A20	Peripheral blood	3.25E-01	-4.22E-02	-4.98E-01
Influenza	1.00E+30	Whole blood	2.73E-03	-4.84E-01	-5.59E+00
Interstitial cystitis	GC00.3	Bladder tissue	2.74E-05	-1.55E+00	-4.39E+00
Intracranial aneurysm	8B01.0	Intracranial artery	2.08E-03	3.99E-01	2.58E+00
Irritable bowel syndrome	DD91.0	Rectal colon tissue	8.50E-01	1.16E-02	2.81E-02
Ischemic stroke	8B11	Peripheral blood	6.25E-01	1.52E-01	3.54E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	7.09E-08	3.33E-01	8.17E-01
Lateral sclerosis	8B60.4	Cervical spinal cord	6.31E-01	-1.10E-01	-5.41E-01
Lateral sclerosis	8B60.4	Skin	1.12E-01	3.55E-01	3.35E+00
Liver cancer	2C12.0	Liver tissue	4.53E-12	2.09E-01	9.71E-01
Liver failure	DB99.7-DB99.8	Liver tissue	1.38E-01	1.15E-01	9.05E-01
Lung cancer	2C25	Lung tissue	1.26E-03	-4.35E-01	-5.28E-01
Lupus erythematosus	4A40	Whole blood	1.43E-01	-9.45E-02	-1.52E-01
Major depressive disorder	6A70-6A7Z	Whole blood	3.15E-01	4.94E-02	1.00E-01
Major depressive disorder	6A70-6A7Z	Hippocampus	9.08E-01	-3.28E-02	-2.63E-01
Melanoma	2C30	Skin	8.75E-02	5.66E-01	5.96E-01
Multiple myeloma	2A83.1	Bone marrow	4.65E-04	-4.21E-01	-2.33E+00
Multiple myeloma	2A83.1	Peripheral blood	6.72E-01	4.32E-02	1.84E-01
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	9.96E-01	-7.25E-02	-1.82E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	7.81E-02	-2.29E-02	-7.70E-02
Myelofibrosis	2A20.2	Whole blood	7.42E-02	3.39E-01	2.35E+00
Myocardial infarction	BA41-BA50	Peripheral blood	5.30E-01	3.95E-01	3.47E-01
Myopathy	8C70.6	Muscle tissue	5.37E-01	4.57E-01	6.89E-01
Neonatal sepsis	KA60	Whole blood	6.38E-14	4.69E-01	1.32E+00
Neuroectodermal tumour	2A00.11	Brain stem tissue	1.37E-01	-3.31E-01	-4.74E-01
Non-alcoholic fatty liver disease	DB92	Liver tissue	4.19E-01	-9.76E-03	-8.17E-02
Obesity related type 2 diabetes	5A11	Omental adipose tissue	6.19E-01	3.46E-02	1.16E-01
Olive pollen allergy	CA08.00	Peripheral blood	1.18E-01	1.44E-01	9.57E-01
Oral cancer	2B6E	Oral tissue	1.63E-15	5.66E-01	2.56E+00
Osteoarthritis	FA00-FA0Z	Synovial tissue	2.49E-01	9.94E-02	2.94E-01
Osteoporosis	FB83.1	Bone marrow	7.16E-01	4.51E-01	2.51E+00
Ovarian cancer	2C73	Ovarian tissue	6.05E-04	8.98E-01	1.91E+00
Pancreatic cancer	2C10	Pancreas	1.26E-02	2.58E-01	6.82E-01
Parkinson's disease	8A00.0	Substantia nigra tissue	3.22E-01	-9.85E-02	-3.01E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	1.12E-02	2.14E-01	8.20E-01
Pituitary cancer	2D12	Pituitary tissue	6.55E-04	2.70E-01	1.55E+00
Pituitary gonadotrope tumour	2D12	Pituitary tissue	1.64E-03	3.45E-01	2.43E+00
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	7.65E-02	-6.01E-02	-6.85E-01
Polycythemia vera	2A20.4	Whole blood	1.81E-05	8.86E-02	6.77E-01
Pompe disease	5C51.3	Biceps muscle	2.68E-02	3.34E-01	1.67E+00
Preterm birth	KA21.4Z	Myometrium	7.61E-02	-1.44E-01	-6.28E-01
Prostate cancer	2C82	Prostate	1.29E-05	1.99E+00	1.55E+00
Psoriasis	EA90	Skin	2.51E-01	-9.70E-02	-3.26E-01
Rectal cancer	2B92	Rectal colon tissue	7.19E-03	5.16E-01	1.81E+00
Renal cancer	2C90-2C91	Kidney	1.04E-01	5.13E-01	6.20E-01
Retinoblastoma	2D02.2	Uvea	1.77E-03	3.10E-01	3.29E+00
Rheumatoid arthritis	FA20	Synovial tissue	3.41E-10	6.77E-01	4.34E+00
Rhinovirus infection	CA42.1	Nasal epithelium tissue	5.63E-01	-5.78E-02	-1.38E-01
Schizophrenia	6A20	Prefrontal cortex	9.83E-02	7.67E-02	1.61E-01
Schizophrenia	6A20	Superior temporal cortex	2.95E-01	2.68E-04	3.79E-03
Scleroderma	4A42.Z	Whole blood	3.18E-02	6.17E-01	1.24E+00
Seizure	8A60-8A6Z	Whole blood	4.53E-02	-1.94E-01	-4.09E-01
Sensitive skin	EK0Z	Skin	6.35E-01	1.09E-01	3.94E-01
Sepsis with septic shock	1G41	Whole blood	2.52E-05	1.35E-01	3.32E-01
Shwachman-Diamond syndrome	3A70.0	Bone marrow	7.94E-03	5.06E-01	2.80E+00
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	6.82E-02	1.01E+00	2.45E+00
Simpson golabi behmel syndrome	LD2C	Adipose tissue	4.24E-01	-8.94E-02	-9.54E-01
Sjogren's syndrome	4A43.2	Salivary gland tissue	5.98E-01	3.01E-03	4.22E-02
Skin cancer	2C30-2C3Z	Skin	3.82E-27	4.31E-01	1.23E+00
Thrombocythemia	3B63	Whole blood	2.28E-01	6.00E-02	4.49E-01
Thrombocytopenia	3B64	Whole blood	5.25E-01	-2.26E-01	-4.88E-01
Thyroid cancer	2D10	Thyroid	1.97E-09	-3.94E-01	-8.48E-01
Tibial muscular dystrophy	8C75	Muscle tissue	4.07E-01	2.22E-01	6.78E-01
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	5.05E-02	2.16E-01	1.59E+00
Type 2 diabetes	5A11	Liver tissue	6.77E-01	3.03E-02	1.51E-01
Ureter cancer	2C92	Urothelium	6.37E-01	7.53E-03	8.24E-02
Uterine cancer	2C78	Endometrium tissue	4.35E-03	8.11E-02	2.44E-01
Vitiligo	ED63.0	Skin	1.45E-02	1.88E-01	7.27E-01