Details of the Drug-Related molecule(s) Expression Atlas

General Information of DTP (ID: DTE8R17)

• DTP Name: Sodium- and chloride-dependent glycine transporter 2 (SLC6A5) DTP Info
• Gene Name: GLYT2

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	4.76E-01	2.77E-02	1.85E-01
Adrenocortical carcinoma	2D11.Z	Kidney	6.96E-01	-5.59E-02	-4.20E-01
Alopecia	ED70	Skin from scalp	2.06E-01	-4.16E-03	-2.95E-02
Alzheimer's disease	8A20	Entorhinal cortex	6.41E-01	-6.40E-03	-4.07E-02
Ankylosing spondylitis	FA92.0	Pheripheral blood	8.74E-01	1.72E-02	1.29E-01
Aortic stenosis	BB70	Calcified aortic valve	9.71E-01	-5.81E-02	-8.71E-02
Apnea	7A40	Hyperplastic tonsil	3.42E-01	9.73E-02	7.80E-01
Arthropathy	FA00-FA5Z	Peripheral blood	1.72E-01	4.93E-02	4.04E-01
Asthma	CA23	Nasal and bronchial airway	1.61E-02	-1.04E-01	-2.96E-01
Atopic dermatitis	EA80	Skin	1.86E-02	4.56E-02	5.55E-01
Autism	6A02	Whole blood	2.30E-01	-2.63E-02	-1.82E-01
Autoimmune uveitis	9A96	Peripheral monocyte	7.09E-02	-2.20E-01	-1.43E+00
Autosomal dominant monocytopenia	4B04	Whole blood	5.03E-01	1.23E-02	1.34E-01
Bacterial infection of gingival	1C1H	Gingival tissue	1.04E-02	5.06E-02	2.32E-01
Batten disease	5C56.1	Whole blood	7.89E-01	-1.82E-02	-1.29E-01
Behcet's disease	4A62	Peripheral blood	5.50E-01	3.81E-02	3.63E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	1.86E-01	-8.34E-02	-4.69E-01
Bladder cancer	2C94	Bladder tissue	9.55E-04	5.11E-01	2.17E+00
Breast cancer	2C60-2C6Z	Breast tissue	6.69E-13	-9.68E-02	-4.12E-01
Cardioembolic stroke	8B11.20	Whole blood	4.59E-03	8.54E-02	6.42E-01
Cervical cancer	2C77	Cervical tissue	5.16E-01	-5.78E-02	-2.16E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	6.66E-01	-1.68E-02	-7.68E-02
Chronic hepatitis C	1E51.1	Whole blood	3.24E-01	7.12E-02	6.01E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	5.41E-02	4.05E-02	2.70E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	6.81E-06	1.14E-01	7.29E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	1.66E-01	9.08E-02	1.14E+00
Colon cancer	2B90	Colon tissue	3.81E-06	-6.57E-02	-3.06E-01
Coronary artery disease	BA80-BA8Z	Peripheral blood	9.72E-01	-3.62E-02	-5.37E-01
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	5.48E-02	-1.92E-01	-8.17E-01
Endometriosis	GA10	Endometrium tissue	6.25E-02	1.46E-01	7.34E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	7.10E-01	1.78E-02	1.35E-01
Familial hypercholesterolemia	5C80.00	Whole blood	5.16E-04	1.21E-01	8.53E-01
Gastric cancer	2B72	Gastric tissue	7.72E-01	-4.90E-02	-3.42E-01
Glioblastopma	2A00.00	Nervous tissue	6.20E-03	-2.77E-02	-9.12E-02
Glioma	2A00.0Y-2A00.0Z	White matter tissue	4.37E-04	-4.87E-01	-1.53E+00
Head and neck cancer	2D42	Head and neck tissue	9.11E-01	-1.85E-02	-1.03E-01
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	1.58E-01	-5.48E-02	-2.34E-01
Huntington's disease	8A01.10	Whole blood	6.29E-01	-6.92E-02	-5.09E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	4.37E-02	-2.12E-01	-1.84E+00
Immunodeficiency	4A00-4A20	Peripheral blood	4.11E-01	8.57E-02	8.13E-01
Influenza	1.00E+30	Whole blood	3.92E-02	3.73E-01	1.79E+00
Interstitial cystitis	GC00.3	Bladder tissue	8.69E-02	6.68E-02	8.67E-01
Intracranial aneurysm	8B01.0	Intracranial artery	8.39E-01	-2.62E-02	-1.62E-01
Irritable bowel syndrome	DD91.0	Rectal colon tissue	4.83E-01	1.63E-01	4.10E-01
Ischemic stroke	8B11	Peripheral blood	6.75E-01	2.95E-02	2.87E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	5.46E-03	9.73E-02	4.25E-01
Lateral sclerosis	8B60.4	Cervical spinal cord	8.21E-01	-1.22E-01	-2.59E-01
Lateral sclerosis	8B60.4	Skin	4.13E-01	1.89E-02	2.20E-01
Liver cancer	2C12.0	Liver tissue	5.63E-09	-1.85E-01	-1.22E+00
Liver failure	DB99.7-DB99.8	Liver tissue	7.61E-01	-2.96E-02	-2.01E-01
Lung cancer	2C25	Lung tissue	6.52E-01	8.47E-03	4.83E-02
Lupus erythematosus	4A40	Whole blood	8.04E-01	-4.17E-02	-1.12E-01
Major depressive disorder	6A70-6A7Z	Whole blood	1.92E-01	4.30E-02	2.04E-01
Major depressive disorder	6A70-6A7Z	Hippocampus	6.96E-01	-2.46E-02	-1.41E-01
Melanoma	2C30	Skin	6.58E-01	1.75E-01	2.82E-01
Multiple myeloma	2A83.1	Bone marrow	3.86E-02	-1.95E-01	-9.68E-01
Multiple myeloma	2A83.1	Peripheral blood	7.83E-02	6.84E-02	4.34E-01
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	5.41E-02	9.49E-02	7.71E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	4.06E-01	-5.55E-02	-2.44E-01
Myelofibrosis	2A20.2	Whole blood	1.98E-04	1.10E-01	1.20E+00
Myocardial infarction	BA41-BA50	Peripheral blood	1.91E-02	1.85E-01	5.93E-01
Myopathy	8C70.6	Muscle tissue	1.25E-02	-1.73E-01	-1.39E+00
Neonatal sepsis	KA60	Whole blood	2.57E-02	6.37E-02	3.40E-01
Neuroectodermal tumour	2A00.11	Brain stem tissue	4.85E-06	-1.38E+00	-2.79E+00
Non-alcoholic fatty liver disease	DB92	Liver tissue	6.30E-01	1.82E-02	1.09E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	7.64E-02	8.25E-02	1.81E+00
Olive pollen allergy	CA08.00	Peripheral blood	3.77E-02	1.41E-01	9.53E-01
Oral cancer	2B6E	Oral tissue	5.37E-05	-2.72E-01	-1.27E+00
Osteoarthritis	FA00-FA0Z	Synovial tissue	7.50E-01	-8.80E-02	-5.20E-01
Osteoporosis	FB83.1	Bone marrow	9.43E-02	1.03E-01	1.31E+00
Ovarian cancer	2C73	Ovarian tissue	2.31E-02	-3.08E-01	-8.88E-01
Pancreatic cancer	2C10	Pancreas	2.19E-03	-1.88E-01	-1.28E+00
Parkinson's disease	8A00.0	Substantia nigra tissue	5.44E-01	-6.94E-02	-3.09E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	1.90E-01	-4.36E-02	-3.08E-01
Pituitary cancer	2D12	Pituitary tissue	6.78E-04	5.48E-01	1.42E+00
Pituitary gonadotrope tumour	2D12	Pituitary tissue	4.44E-04	8.11E-01	1.99E+00
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	2.12E-01	-3.17E-02	-3.78E-01
Polycythemia vera	2A20.4	Whole blood	2.76E-09	1.42E-01	1.36E+00
Pompe disease	5C51.3	Biceps muscle	3.48E-02	-9.88E-02	-9.44E-01
Preterm birth	KA21.4Z	Myometrium	4.48E-01	-1.88E-02	-2.50E-01
Prostate cancer	2C82	Prostate	7.02E-02	-3.41E-01	-7.52E-01
Psoriasis	EA90	Skin	7.14E-08	-1.15E-01	-3.90E-01
Rectal cancer	2B92	Rectal colon tissue	5.45E-01	1.35E-02	1.17E-01
Renal cancer	2C90-2C91	Kidney	3.66E-02	-2.13E-01	-7.76E-01
Retinoblastoma	2D02.2	Uvea	5.25E-01	-6.84E-02	-8.57E-01
Rheumatoid arthritis	FA20	Synovial tissue	3.51E-01	-1.91E-01	-5.97E-01
Rhinovirus infection	CA42.1	Nasal epithelium tissue	6.21E-01	-1.57E-02	-1.42E-01
Schizophrenia	6A20	Prefrontal cortex	8.70E-01	1.64E-02	8.80E-02
Schizophrenia	6A20	Superior temporal cortex	8.76E-01	-1.33E-02	-9.49E-02
Scleroderma	4A42.Z	Whole blood	9.72E-01	1.25E-02	6.36E-02
Seizure	8A60-8A6Z	Whole blood	2.68E-01	-1.14E-01	-6.12E-01
Sensitive skin	EK0Z	Skin	3.52E-01	1.20E-02	7.45E-02
Sepsis with septic shock	1G41	Whole blood	8.92E-02	1.49E-02	7.89E-02
Shwachman-Diamond syndrome	3A70.0	Bone marrow	9.25E-01	4.86E-02	2.57E-01
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	5.06E-01	6.67E-02	2.68E-01
Simpson golabi behmel syndrome	LD2C	Adipose tissue	2.65E-02	1.40E-01	5.05E+00
Sjogren's syndrome	4A43.2	Salivary gland tissue	4.57E-01	-1.36E-01	-7.50E-01
Skin cancer	2C30-2C3Z	Skin	6.73E-02	-1.17E-01	-3.25E-01
Thrombocythemia	3B63	Whole blood	2.08E-04	2.06E-01	1.99E+00
Thrombocytopenia	3B64	Whole blood	2.23E-01	2.11E-02	1.24E-01
Thyroid cancer	2D10	Thyroid	9.06E-01	-1.31E-02	-7.43E-02
Tibial muscular dystrophy	8C75	Muscle tissue	1.95E-02	-1.37E-01	-7.86E-01
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	1.02E-01	6.76E-02	3.08E+00
Type 2 diabetes	5A11	Liver tissue	4.33E-01	-7.44E-02	-6.59E-01
Ureter cancer	2C92	Urothelium	6.46E-01	-2.95E-03	-1.21E-02
Uterine cancer	2C78	Endometrium tissue	2.19E-02	-6.28E-02	-2.53E-01
Vitiligo	ED63.0	Skin	4.16E-03	-2.03E-01	-1.69E+00