Details of the Drug-Related molecule(s) Expression Atlas

General Information of DTP (ID: DTF9Y2V)

• DTP Name: ATP-binding cassette sub-family B member 6 (ABCB6) DTP Info
• Gene Name: ABCB6

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	3.27E-19	-5.46E-01	-1.32E+00
Adrenocortical carcinoma	2D11.Z	Kidney	2.15E-02	1.16E-01	6.65E-01
Alopecia	ED70	Skin from scalp	1.27E-04	-1.95E-01	-6.41E-01
Alzheimer's disease	8A20	Entorhinal cortex	1.01E-01	-3.67E-02	-2.58E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	8.36E-01	-2.39E-02	-1.85E-01
Aortic stenosis	BB70	Calcified aortic valve	2.27E-01	-1.22E-01	-5.47E-01
Apnea	7A40	Hyperplastic tonsil	1.84E-01	-1.36E-01	-5.88E-01
Arthropathy	FA00-FA5Z	Peripheral blood	5.42E-01	-6.18E-02	-3.03E-01
Asthma	CA23	Nasal and bronchial airway	5.83E-01	5.44E-02	1.76E-01
Atopic dermatitis	EA80	Skin	7.15E-05	2.02E-01	1.28E+00
Autism	6A02	Whole blood	1.82E-01	-1.22E-01	-5.82E-01
Autoimmune uveitis	9A96	Peripheral monocyte	1.22E-03	-3.37E-01	-2.18E+00
Autosomal dominant monocytopenia	4B04	Whole blood	6.88E-01	1.90E-02	1.86E-01
Bacterial infection of gingival	1C1H	Gingival tissue	1.07E-01	7.38E-02	2.56E-01
Batten disease	5C56.1	Whole blood	5.58E-01	1.12E-01	7.58E-01
Behcet's disease	4A62	Peripheral blood	2.26E-01	1.11E-01	4.41E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	6.51E-01	-3.13E-02	-2.30E-01
Bladder cancer	2C94	Bladder tissue	2.00E-01	-1.30E-01	-7.59E-01
Breast cancer	2C60-2C6Z	Breast tissue	5.43E-02	-6.40E-02	-1.75E-01
Cardioembolic stroke	8B11.20	Whole blood	9.93E-01	-4.12E-03	-2.51E-02
Cervical cancer	2C77	Cervical tissue	4.98E-01	-7.09E-02	-2.65E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	1.18E-01	1.95E-02	8.01E-02
Chronic hepatitis C	1E51.1	Whole blood	2.67E-01	1.05E-01	5.64E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	3.01E-01	-1.34E-01	-4.37E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	1.81E-05	3.04E-01	7.26E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	1.72E-01	-2.13E-01	-9.32E-01
Colon cancer	2B90	Colon tissue	3.20E-17	2.35E-01	8.00E-01
Coronary artery disease	BA80-BA8Z	Peripheral blood	8.88E-02	1.12E-01	2.40E+00
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	7.20E-01	-6.44E-02	-3.05E-01
Endometriosis	GA10	Endometrium tissue	2.19E-01	2.37E-02	6.21E-02
Familial hypercholesterolemia	5C80.00	Peripheral blood	3.29E-01	6.08E-02	3.77E-01
Familial hypercholesterolemia	5C80.00	Whole blood	9.56E-01	2.81E-02	9.55E-02
Gastric cancer	2B72	Gastric tissue	1.38E-01	1.58E-01	1.31E+00
Glioblastopma	2A00.00	Nervous tissue	5.65E-01	6.64E-03	2.83E-02
Glioma	2A00.0Y-2A00.0Z	White matter tissue	3.57E-01	5.39E-03	1.57E-02
Head and neck cancer	2D42	Head and neck tissue	7.73E-02	-6.88E-02	-2.41E-01
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	8.53E-01	-6.77E-02	-2.63E-01
Huntington's disease	8A01.10	Whole blood	1.82E-01	1.56E-01	8.64E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	4.31E-01	-2.28E-01	-1.14E+00
Immunodeficiency	4A00-4A20	Peripheral blood	4.81E-01	3.24E-02	2.48E-01
Influenza	1.00E+30	Whole blood	1.47E-01	1.30E-01	9.47E-01
Interstitial cystitis	GC00.3	Bladder tissue	7.40E-04	-3.71E-01	-3.00E+00
Intracranial aneurysm	8B01.0	Intracranial artery	2.65E-01	1.41E-01	4.23E-01
Irritable bowel syndrome	DD91.0	Rectal colon tissue	2.54E-01	-2.65E-02	-1.10E-01
Ischemic stroke	8B11	Peripheral blood	2.93E-01	1.08E-01	4.20E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	3.02E-01	-5.53E-03	-1.55E-02
Lateral sclerosis	8B60.4	Cervical spinal cord	6.01E-01	7.89E-02	3.04E-01
Lateral sclerosis	8B60.4	Skin	6.54E-01	-1.02E-01	-3.20E-01
Liver cancer	2C12.0	Liver tissue	4.88E-01	4.06E-02	1.45E-01
Liver failure	DB99.7-DB99.8	Liver tissue	7.05E-01	-6.73E-02	-1.81E-01
Lung cancer	2C25	Lung tissue	3.53E-53	4.71E-01	1.80E+00
Lupus erythematosus	4A40	Whole blood	7.76E-01	-8.91E-03	-2.52E-02
Major depressive disorder	6A70-6A7Z	Whole blood	3.78E-01	-1.10E-02	-4.97E-02
Major depressive disorder	6A70-6A7Z	Hippocampus	5.19E-01	1.74E-03	1.33E-02
Melanoma	2C30	Skin	2.32E-01	-1.61E-01	-3.94E-01
Multiple myeloma	2A83.1	Bone marrow	7.55E-02	1.72E-01	8.35E-01
Multiple myeloma	2A83.1	Peripheral blood	9.22E-01	-3.35E-02	-7.81E-02
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	8.60E-01	2.24E-01	8.04E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	9.51E-02	3.09E-02	1.28E-01
Myelofibrosis	2A20.2	Whole blood	8.67E-03	4.13E-01	2.51E+00
Myocardial infarction	BA41-BA50	Peripheral blood	6.55E-02	7.87E-02	2.97E-01
Myopathy	8C70.6	Muscle tissue	6.85E-02	-3.29E-01	-1.39E+00
Neonatal sepsis	KA60	Whole blood	9.35E-01	-7.38E-02	-2.31E-01
Neuroectodermal tumour	2A00.11	Brain stem tissue	7.41E-09	4.61E-01	3.83E+00
Non-alcoholic fatty liver disease	DB92	Liver tissue	1.38E-02	-3.81E-01	-1.37E+00
Obesity related type 2 diabetes	5A11	Omental adipose tissue	8.82E-01	-2.92E-03	-1.83E-02
Olive pollen allergy	CA08.00	Peripheral blood	2.14E-01	1.81E-01	5.51E-01
Oral cancer	2B6E	Oral tissue	8.72E-06	-4.50E-01	-9.60E-01
Osteoarthritis	FA00-FA0Z	Synovial tissue	1.55E-01	-4.10E-01	-7.74E-01
Osteoporosis	FB83.1	Bone marrow	5.38E-01	9.57E-02	6.42E-01
Ovarian cancer	2C73	Ovarian tissue	8.68E-02	-2.32E-01	-7.27E-01
Pancreatic cancer	2C10	Pancreas	7.87E-01	2.72E-04	1.09E-03
Parkinson's disease	8A00.0	Substantia nigra tissue	8.88E-02	1.85E-01	8.15E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	1.32E-01	-1.03E-01	-5.65E-01
Pituitary cancer	2D12	Pituitary tissue	1.15E-01	1.14E-01	3.99E-01
Pituitary gonadotrope tumour	2D12	Pituitary tissue	7.06E-01	-5.07E-02	-1.52E-01
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	4.76E-01	-2.44E-02	-6.43E-02
Polycythemia vera	2A20.4	Whole blood	3.13E-08	2.00E-01	1.15E+00
Pompe disease	5C51.3	Biceps muscle	3.52E-02	1.87E-01	1.64E+00
Preterm birth	KA21.4Z	Myometrium	5.28E-01	-2.14E-01	-5.86E-01
Prostate cancer	2C82	Prostate	4.25E-05	5.43E-01	1.13E+00
Psoriasis	EA90	Skin	4.39E-35	5.22E-01	2.09E+00
Rectal cancer	2B92	Rectal colon tissue	3.97E-02	2.82E-01	8.99E-01
Renal cancer	2C90-2C91	Kidney	3.13E-02	1.87E-01	6.30E-01
Retinoblastoma	2D02.2	Uvea	2.89E-01	-8.12E-02	-6.16E-01
Rheumatoid arthritis	FA20	Synovial tissue	3.86E-01	-5.04E-01	-7.98E-01
Rhinovirus infection	CA42.1	Nasal epithelium tissue	7.58E-02	-4.63E-02	-3.68E-01
Schizophrenia	6A20	Prefrontal cortex	6.83E-01	-2.67E-02	-8.84E-02
Schizophrenia	6A20	Superior temporal cortex	6.70E-01	-5.60E-02	-4.26E-01
Scleroderma	4A42.Z	Whole blood	6.82E-03	-2.40E-01	-1.43E+00
Seizure	8A60-8A6Z	Whole blood	9.71E-01	9.14E-03	5.23E-02
Sensitive skin	EK0Z	Skin	4.49E-01	7.96E-02	3.88E-01
Sepsis with septic shock	1G41	Whole blood	9.81E-01	-7.52E-02	-2.19E-01
Shwachman-Diamond syndrome	3A70.0	Bone marrow	9.92E-01	-7.59E-02	-5.07E-01
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	4.49E-03	1.67E-01	6.59E-01
Simpson golabi behmel syndrome	LD2C	Adipose tissue	1.45E-01	5.73E-01	1.67E+00
Sjogren's syndrome	4A43.2	Salivary gland tissue	6.21E-01	6.33E-02	7.92E-01
Skin cancer	2C30-2C3Z	Skin	2.37E-38	4.39E-01	1.44E+00
Thrombocythemia	3B63	Whole blood	4.86E-03	2.43E-02	1.42E-01
Thrombocytopenia	3B64	Whole blood	6.82E-01	2.09E-01	3.29E-01
Thyroid cancer	2D10	Thyroid	6.28E-19	-3.38E-01	-1.61E+00
Tibial muscular dystrophy	8C75	Muscle tissue	4.37E-06	-5.64E-01	-2.60E+00
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	5.77E-01	-1.33E-02	-8.99E-02
Type 2 diabetes	5A11	Liver tissue	6.76E-01	-1.02E-01	-4.74E-01
Ureter cancer	2C92	Urothelium	8.18E-02	1.24E-01	6.35E-01
Uterine cancer	2C78	Endometrium tissue	1.22E-06	1.73E-01	5.14E-01
Vitiligo	ED63.0	Skin	3.02E-01	-1.17E-01	-7.55E-01