Details of the Drug-Related molecule(s) Expression Atlas

General Information of DTP (ID: DTFI42L)

• DTP Name: Multidrug resistance-associated protein 2 (ABCC2) DTP Info
• Gene Name: MRP2

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	1.29E-14	-3.25E-01	-7.49E-01
Adrenocortical carcinoma	2D11.Z	Kidney	6.05E-01	-6.69E-02	-1.18E-01
Alopecia	ED70	Skin from scalp	4.03E-01	3.49E-02	1.11E-01
Alzheimer's disease	8A20	Entorhinal cortex	7.16E-01	-1.28E-02	-6.06E-02
Ankylosing spondylitis	FA92.0	Pheripheral blood	2.49E-01	1.29E-01	7.94E-01
Aortic stenosis	BB70	Calcified aortic valve	8.86E-01	7.20E-03	1.84E-02
Apnea	7A40	Hyperplastic tonsil	3.64E-01	9.84E-02	6.62E-01
Arthropathy	FA00-FA5Z	Peripheral blood	3.63E-01	4.16E-02	2.24E-01
Asthma	CA23	Nasal and bronchial airway	7.82E-01	2.14E-03	4.38E-03
Atopic dermatitis	EA80	Skin	2.52E-01	1.05E-02	8.67E-02
Autism	6A02	Whole blood	8.54E-01	-3.99E-02	-1.31E-01
Autoimmune uveitis	9A96	Peripheral monocyte	4.81E-01	4.69E-02	2.89E-01
Autosomal dominant monocytopenia	4B04	Whole blood	2.05E-01	4.07E-01	1.62E+00
Bacterial infection of gingival	1C1H	Gingival tissue	6.91E-01	6.87E-03	3.05E-02
Batten disease	5C56.1	Whole blood	7.00E-01	1.86E-01	1.07E+00
Behcet's disease	4A62	Peripheral blood	3.08E-01	7.35E-02	3.54E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	8.63E-01	9.14E-03	5.41E-02
Bladder cancer	2C94	Bladder tissue	9.44E-01	-1.80E-01	-5.06E-01
Breast cancer	2C60-2C6Z	Breast tissue	2.95E-07	-2.11E-01	-4.00E-01
Cardioembolic stroke	8B11.20	Whole blood	2.54E-06	6.44E-01	1.49E+00
Cervical cancer	2C77	Cervical tissue	7.81E-01	3.85E-02	1.27E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	4.19E-01	-8.92E-02	-1.73E-01
Chronic hepatitis C	1E51.1	Whole blood	7.73E-01	-2.06E-02	-1.29E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	3.49E-01	6.59E-02	3.03E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	3.57E-01	-8.50E-02	-2.09E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	2.19E-01	0.00E+00	0.00E+00
Colon cancer	2B90	Colon tissue	1.42E-20	2.40E-01	5.69E-01
Coronary artery disease	BA80-BA8Z	Peripheral blood	2.45E-01	-3.27E-01	-1.24E+00
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	3.39E-01	-9.43E-02	-1.75E-01
Endometriosis	GA10	Endometrium tissue	6.57E-01	-7.03E-03	-3.29E-02
Familial hypercholesterolemia	5C80.00	Peripheral blood	8.01E-01	-9.49E-02	-6.06E-01
Familial hypercholesterolemia	5C80.00	Whole blood	4.30E-02	-2.29E-01	-9.10E-01
Gastric cancer	2B72	Gastric tissue	4.48E-02	1.85E-01	9.45E-01
Glioblastopma	2A00.00	Nervous tissue	6.76E-01	2.25E-02	7.43E-02
Glioma	2A00.0Y-2A00.0Z	White matter tissue	2.04E-01	-1.77E-01	-5.42E-01
Head and neck cancer	2D42	Head and neck tissue	5.32E-02	-1.36E-01	-2.97E-01
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	1.17E-02	-1.29E-01	-4.98E-01
Huntington's disease	8A01.10	Whole blood	1.38E-01	6.18E-02	4.19E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	1.80E-01	-1.17E-01	-7.13E-01
Immunodeficiency	4A00-4A20	Peripheral blood	5.49E-01	-2.68E-02	-2.25E-01
Influenza	1.00E+30	Whole blood	5.14E-01	1.28E-01	4.45E-01
Interstitial cystitis	GC00.3	Bladder tissue	6.75E-01	-2.47E-03	-9.45E-03
Intracranial aneurysm	8B01.0	Intracranial artery	1.25E-03	-3.79E-01	-9.14E-01
Irritable bowel syndrome	DD91.0	Rectal colon tissue	5.23E-01	8.97E-03	3.36E-02
Ischemic stroke	8B11	Peripheral blood	6.64E-01	-1.38E-02	-9.45E-02
Juvenile idiopathic arthritis	FA24	Peripheral blood	1.46E-02	-1.88E-01	-3.83E-01
Lateral sclerosis	8B60.4	Cervical spinal cord	8.87E-01	1.81E-01	6.06E-01
Lateral sclerosis	8B60.4	Skin	9.30E-01	2.49E-03	1.31E-02
Liver cancer	2C12.0	Liver tissue	3.26E-02	2.25E-02	3.48E-02
Liver failure	DB99.7-DB99.8	Liver tissue	1.45E-02	-1.98E+00	-3.61E+00
Lung cancer	2C25	Lung tissue	1.02E-08	-5.12E-02	-2.22E-01
Lupus erythematosus	4A40	Whole blood	7.36E-09	3.25E-01	6.71E-01
Major depressive disorder	6A70-6A7Z	Whole blood	5.42E-02	1.01E-01	2.09E-01
Major depressive disorder	6A70-6A7Z	Hippocampus	1.85E-02	5.14E-02	3.36E-01
Melanoma	2C30	Skin	3.60E-03	5.12E-02	6.03E-02
Multiple myeloma	2A83.1	Bone marrow	2.22E-01	-1.68E-01	-6.27E-01
Multiple myeloma	2A83.1	Peripheral blood	2.44E-01	6.35E-02	3.90E-01
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	4.24E-01	2.07E-01	6.55E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	8.42E-01	6.53E-04	5.72E-03
Myelofibrosis	2A20.2	Whole blood	5.87E-01	-2.27E-02	-1.39E-01
Myocardial infarction	BA41-BA50	Peripheral blood	6.93E-01	9.50E-02	1.25E-01
Myopathy	8C70.6	Muscle tissue	1.38E-01	-1.42E-01	-8.33E-01
Neonatal sepsis	KA60	Whole blood	2.04E-05	1.82E-01	6.30E-01
Neuroectodermal tumour	2A00.11	Brain stem tissue	7.79E-04	-8.57E-01	-1.99E+00
Non-alcoholic fatty liver disease	DB92	Liver tissue	8.73E-01	3.60E-02	8.80E-02
Obesity related type 2 diabetes	5A11	Omental adipose tissue	1.94E-01	3.14E-01	2.46E+00
Olive pollen allergy	CA08.00	Peripheral blood	1.05E-01	-2.11E-01	-1.36E+00
Oral cancer	2B6E	Oral tissue	2.89E-03	-2.40E-01	-9.52E-01
Osteoarthritis	FA00-FA0Z	Synovial tissue	5.68E-01	5.84E-03	1.64E-02
Osteoporosis	FB83.1	Bone marrow	6.56E-01	6.43E-02	2.99E-01
Ovarian cancer	2C73	Ovarian tissue	9.91E-01	-4.05E-02	-1.15E-01
Pancreatic cancer	2C10	Pancreas	2.85E-01	-3.85E-01	-9.20E-01
Parkinson's disease	8A00.0	Substantia nigra tissue	6.25E-01	8.95E-02	8.58E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	2.15E-01	8.74E-02	5.78E-01
Pituitary cancer	2D12	Pituitary tissue	1.96E-01	-8.30E-03	-2.10E-02
Pituitary gonadotrope tumour	2D12	Pituitary tissue	2.15E-01	-8.70E-02	-2.24E-01
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	4.68E-01	5.75E-02	3.48E-01
Polycythemia vera	2A20.4	Whole blood	5.58E-03	9.73E-02	5.83E-01
Pompe disease	5C51.3	Biceps muscle	7.81E-01	-8.15E-02	-4.87E-01
Preterm birth	KA21.4Z	Myometrium	5.00E-01	-1.74E-02	-1.81E-01
Prostate cancer	2C82	Prostate	1.58E-01	-4.23E-01	-7.28E-01
Psoriasis	EA90	Skin	7.41E-21	4.03E-01	1.33E+00
Rectal cancer	2B92	Rectal colon tissue	2.34E-03	4.75E-01	1.43E+00
Renal cancer	2C90-2C91	Kidney	5.05E-01	-2.11E-01	-2.62E-01
Retinoblastoma	2D02.2	Uvea	8.84E-02	-7.19E-01	-1.41E+00
Rheumatoid arthritis	FA20	Synovial tissue	5.30E-02	3.89E-01	7.37E-01
Rhinovirus infection	CA42.1	Nasal epithelium tissue	4.20E-01	-4.75E-02	-1.92E-01
Schizophrenia	6A20	Prefrontal cortex	8.96E-02	1.20E-01	3.25E-01
Schizophrenia	6A20	Superior temporal cortex	8.44E-01	1.30E-02	1.07E-01
Scleroderma	4A42.Z	Whole blood	7.59E-01	5.11E-02	1.98E-01
Seizure	8A60-8A6Z	Whole blood	8.88E-01	4.47E-02	1.88E-01
Sensitive skin	EK0Z	Skin	9.43E-01	6.45E-02	3.37E-01
Sepsis with septic shock	1G41	Whole blood	2.71E-24	2.63E-01	7.81E-01
Shwachman-Diamond syndrome	3A70.0	Bone marrow	4.53E-01	4.05E-01	1.36E+00
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	4.40E-02	1.38E-01	6.50E-01
Simpson golabi behmel syndrome	LD2C	Adipose tissue	7.16E-01	1.73E-01	1.25E+00
Sjogren's syndrome	4A43.2	Salivary gland tissue	7.84E-01	8.30E-03	2.75E-01
Skin cancer	2C30-2C3Z	Skin	7.78E-17	2.20E-01	4.83E-01
Thrombocythemia	3B63	Whole blood	6.94E-03	8.23E-02	4.95E-01
Thrombocytopenia	3B64	Whole blood	3.99E-01	1.71E-01	3.53E-01
Thyroid cancer	2D10	Thyroid	1.52E-01	3.61E-02	1.60E-01
Tibial muscular dystrophy	8C75	Muscle tissue	1.49E-06	-6.14E-01	-2.68E+00
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	7.68E-01	5.74E-02	5.34E-01
Type 2 diabetes	5A11	Liver tissue	7.65E-01	-2.63E-02	-1.32E-01
Ureter cancer	2C92	Urothelium	1.26E-01	-1.20E-01	-5.95E-01
Uterine cancer	2C78	Endometrium tissue	1.96E-01	3.38E-02	1.08E-01
Vitiligo	ED63.0	Skin	1.33E-02	-3.60E-01	-1.43E+00