Details of the Drug-Related molecule(s) Expression Atlas

General Information of DTP (ID: DTH1GEL)

• DTP Name: Sodium-dependent proline transporter (SLC6A7) DTP Info
• Gene Name: PROT

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	1.14E-01	-6.75E-02	-2.79E-01
Adrenocortical carcinoma	2D11.Z	Kidney	7.36E-01	2.09E-03	9.11E-03
Alopecia	ED70	Skin from scalp	6.64E-02	-6.11E-02	-2.65E-01
Alzheimer's disease	8A20	Entorhinal cortex	1.15E-08	-4.43E-01	-8.09E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	5.49E-02	2.13E-01	7.68E-01
Aortic stenosis	BB70	Calcified aortic valve	7.05E-01	-1.15E-02	-3.61E-02
Apnea	7A40	Hyperplastic tonsil	1.61E-01	9.70E-03	7.48E-02
Arthropathy	FA00-FA5Z	Peripheral blood	4.66E-02	6.32E-02	3.84E-01
Asthma	CA23	Nasal and bronchial airway	8.01E-02	-7.93E-02	-2.27E-01
Atopic dermatitis	EA80	Skin	5.07E-05	-1.33E-01	-8.50E-01
Autism	6A02	Whole blood	7.84E-01	-2.98E-02	-1.12E-01
Autoimmune uveitis	9A96	Peripheral monocyte	3.15E-02	-2.73E-01	-1.60E+00
Autosomal dominant monocytopenia	4B04	Whole blood	7.00E-01	-4.08E-02	-2.03E-01
Bacterial infection of gingival	1C1H	Gingival tissue	1.68E-03	8.84E-02	4.47E-01
Batten disease	5C56.1	Whole blood	1.03E-02	1.74E-01	1.49E+00
Behcet's disease	4A62	Peripheral blood	5.23E-01	-6.06E-03	-3.27E-02
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	6.44E-01	-1.00E-02	-5.83E-02
Bladder cancer	2C94	Bladder tissue	6.43E-01	-2.90E-04	-1.42E-03
Breast cancer	2C60-2C6Z	Breast tissue	3.01E-33	2.02E-01	9.22E-01
Cardioembolic stroke	8B11.20	Whole blood	2.15E-02	5.99E-02	3.48E-01
Cervical cancer	2C77	Cervical tissue	3.40E-03	-7.17E-02	-4.86E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	7.67E-01	2.88E-02	1.03E-01
Chronic hepatitis C	1E51.1	Whole blood	6.17E-01	1.79E-02	1.29E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	9.28E-01	-3.33E-02	-1.49E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	2.24E-02	9.97E-02	4.83E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	3.93E-01	-6.17E-02	-7.36E-01
Colon cancer	2B90	Colon tissue	2.65E-09	-1.61E-01	-6.90E-01
Coronary artery disease	BA80-BA8Z	Peripheral blood	7.55E-02	1.56E-01	8.32E-01
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	8.19E-01	2.00E-02	8.41E-02
Endometriosis	GA10	Endometrium tissue	6.10E-01	3.65E-02	1.21E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	8.67E-01	-3.86E-02	-2.08E-01
Familial hypercholesterolemia	5C80.00	Whole blood	2.29E-02	-1.83E-01	-6.28E-01
Gastric cancer	2B72	Gastric tissue	9.80E-03	2.80E-01	5.18E+00
Glioblastopma	2A00.00	Nervous tissue	1.11E-54	-4.46E-01	-8.74E-01
Glioma	2A00.0Y-2A00.0Z	White matter tissue	1.46E-02	-5.66E-01	-1.43E+00
Head and neck cancer	2D42	Head and neck tissue	8.09E-02	4.35E-02	2.28E-01
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	8.81E-02	-6.59E-02	-2.22E-01
Huntington's disease	8A01.10	Whole blood	3.42E-01	1.06E-01	6.64E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	7.08E-01	9.76E-02	3.55E-01
Immunodeficiency	4A00-4A20	Peripheral blood	6.93E-01	2.36E-02	1.99E-01
Influenza	1.00E+30	Whole blood	2.80E-01	2.85E-01	1.35E+00
Interstitial cystitis	GC00.3	Bladder tissue	1.95E-01	1.19E-01	6.96E-01
Intracranial aneurysm	8B01.0	Intracranial artery	4.25E-01	8.76E-02	3.32E-01
Irritable bowel syndrome	DD91.0	Rectal colon tissue	7.18E-01	-1.00E-02	-3.92E-02
Ischemic stroke	8B11	Peripheral blood	9.94E-02	5.90E-02	3.19E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	1.08E-02	5.66E-02	1.85E-01
Lateral sclerosis	8B60.4	Cervical spinal cord	8.97E-02	3.57E-01	1.07E+00
Lateral sclerosis	8B60.4	Skin	2.67E-02	-2.47E-01	-2.23E+00
Liver cancer	2C12.0	Liver tissue	9.03E-08	-1.87E-01	-9.26E-01
Liver failure	DB99.7-DB99.8	Liver tissue	7.94E-03	-1.42E-01	-1.09E+00
Lung cancer	2C25	Lung tissue	5.11E-01	3.25E-02	1.52E-01
Lupus erythematosus	4A40	Whole blood	3.28E-01	-8.51E-02	-1.78E-01
Major depressive disorder	6A70-6A7Z	Whole blood	1.27E-01	3.76E-02	1.55E-01
Major depressive disorder	6A70-6A7Z	Hippocampus	7.10E-02	7.92E-02	4.51E-01
Melanoma	2C30	Skin	9.03E-01	5.94E-02	1.41E-01
Multiple myeloma	2A83.1	Bone marrow	3.04E-02	9.65E-02	5.78E-01
Multiple myeloma	2A83.1	Peripheral blood	1.36E-01	-9.62E-02	-5.08E-01
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	1.41E-01	1.31E-01	4.09E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	5.33E-01	-3.05E-02	-1.54E-01
Myelofibrosis	2A20.2	Whole blood	2.17E-01	-7.70E-04	-3.83E-03
Myocardial infarction	BA41-BA50	Peripheral blood	1.03E-01	4.07E-01	7.08E-01
Myopathy	8C70.6	Muscle tissue	4.63E-01	-5.01E-02	-2.61E-01
Neonatal sepsis	KA60	Whole blood	6.99E-04	-1.53E-01	-4.25E-01
Neuroectodermal tumour	2A00.11	Brain stem tissue	6.68E-01	9.35E-03	2.42E-02
Non-alcoholic fatty liver disease	DB92	Liver tissue	2.16E-01	-7.38E-02	-4.14E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	7.32E-01	2.59E-02	1.96E-01
Olive pollen allergy	CA08.00	Peripheral blood	9.63E-02	1.56E-02	2.35E-01
Oral cancer	2B6E	Oral tissue	3.32E-03	-1.84E-01	-6.75E-01
Osteoarthritis	FA00-FA0Z	Synovial tissue	5.62E-01	-3.45E-03	-1.08E-02
Osteoporosis	FB83.1	Bone marrow	2.71E-01	1.16E-01	6.19E-01
Ovarian cancer	2C73	Ovarian tissue	3.09E-01	-2.32E-01	-5.30E-01
Pancreatic cancer	2C10	Pancreas	4.18E-03	-2.75E-01	-8.24E-01
Parkinson's disease	8A00.0	Substantia nigra tissue	4.86E-01	-8.37E-03	-6.35E-02
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	7.36E-02	6.56E-02	5.76E-01
Pituitary cancer	2D12	Pituitary tissue	9.50E-03	2.02E-01	1.08E+00
Pituitary gonadotrope tumour	2D12	Pituitary tissue	8.50E-02	9.40E-02	6.56E-01
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	6.70E-02	6.89E-02	7.09E-01
Polycythemia vera	2A20.4	Whole blood	3.89E-01	6.17E-02	3.29E-01
Pompe disease	5C51.3	Biceps muscle	5.97E-02	-9.12E-02	-4.27E-01
Preterm birth	KA21.4Z	Myometrium	5.82E-01	1.39E-02	1.51E-01
Prostate cancer	2C82	Prostate	2.92E-01	-2.25E-01	-5.24E-01
Psoriasis	EA90	Skin	8.52E-02	-4.17E-02	-8.92E-02
Rectal cancer	2B92	Rectal colon tissue	5.92E-01	-1.21E-01	-5.16E-01
Renal cancer	2C90-2C91	Kidney	7.19E-01	-1.47E-02	-6.44E-02
Retinoblastoma	2D02.2	Uvea	3.42E-01	-8.90E-02	-7.35E-01
Rheumatoid arthritis	FA20	Synovial tissue	1.24E-01	-7.64E-02	-2.38E-01
Rhinovirus infection	CA42.1	Nasal epithelium tissue	6.42E-01	-5.16E-03	-3.25E-02
Schizophrenia	6A20	Prefrontal cortex	4.34E-01	-9.89E-03	-2.78E-02
Schizophrenia	6A20	Superior temporal cortex	6.72E-01	2.86E-03	1.57E-02
Scleroderma	4A42.Z	Whole blood	5.86E-01	6.09E-03	5.43E-02
Seizure	8A60-8A6Z	Whole blood	3.16E-01	-3.37E-02	-1.11E-01
Sensitive skin	EK0Z	Skin	5.41E-01	4.09E-03	2.54E-02
Sepsis with septic shock	1G41	Whole blood	8.79E-03	-5.95E-02	-1.87E-01
Shwachman-Diamond syndrome	3A70.0	Bone marrow	8.29E-03	3.56E-01	2.18E+00
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	4.29E-02	1.10E-01	4.70E-01
Simpson golabi behmel syndrome	LD2C	Adipose tissue	2.56E-01	3.14E-02	3.34E-01
Sjogren's syndrome	4A43.2	Salivary gland tissue	1.63E-01	-5.59E-01	-1.24E+00
Skin cancer	2C30-2C3Z	Skin	1.71E-06	-1.98E-01	-4.02E-01
Thrombocythemia	3B63	Whole blood	7.14E-01	5.77E-03	3.07E-02
Thrombocytopenia	3B64	Whole blood	1.15E-01	-1.65E-01	-8.02E-01
Thyroid cancer	2D10	Thyroid	1.44E-04	7.01E-02	3.10E-01
Tibial muscular dystrophy	8C75	Muscle tissue	1.20E-03	-2.46E-01	-9.76E-01
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	2.07E-01	-1.84E-01	-8.63E-01
Type 2 diabetes	5A11	Liver tissue	3.03E-01	-1.54E-01	-4.75E-01
Ureter cancer	2C92	Urothelium	4.71E-01	-8.61E-02	-3.16E-01
Uterine cancer	2C78	Endometrium tissue	1.98E-02	-5.76E-02	-2.18E-01
Vitiligo	ED63.0	Skin	2.89E-01	-5.67E-02	-3.91E-01