Details of the Drug-Related molecule(s) Expression Atlas

General Information of DTP (ID: DTJCWP8)

• DTP Name: Mitochondrial glutamate carrier 1 (SLC25A22) DTP Info
• Gene Name: GC1

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	6.00E-10	2.03E-01	7.28E-01
Adrenocortical carcinoma	2D11.Z	Kidney	1.98E-01	2.12E-01	5.87E-01
Alopecia	ED70	Skin from scalp	2.41E-01	2.48E-02	8.45E-02
Alzheimer's disease	8A20	Entorhinal cortex	1.35E-09	-4.19E-01	-9.19E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	8.86E-01	-1.90E-02	-1.29E-01
Aortic stenosis	BB70	Calcified aortic valve	4.60E-01	3.36E-02	7.31E-02
Apnea	7A40	Hyperplastic tonsil	8.37E-01	-5.33E-02	-2.15E-01
Arthropathy	FA00-FA5Z	Peripheral blood	1.91E-01	-6.86E-02	-4.82E-01
Asthma	CA23	Nasal and bronchial airway	8.39E-01	-4.39E-02	-9.22E-02
Atopic dermatitis	EA80	Skin	7.65E-10	4.57E-01	2.22E+00
Autism	6A02	Whole blood	7.30E-01	-1.15E-02	-5.29E-02
Autoimmune uveitis	9A96	Peripheral monocyte	8.99E-01	3.40E-02	1.47E-01
Autosomal dominant monocytopenia	4B04	Whole blood	5.83E-01	4.84E-02	2.81E-01
Bacterial infection of gingival	1C1H	Gingival tissue	8.32E-01	-7.99E-03	-2.44E-02
Batten disease	5C56.1	Whole blood	3.18E-01	-1.41E-01	-7.75E-01
Behcet's disease	4A62	Peripheral blood	2.86E-01	6.37E-02	1.98E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	9.20E-01	-6.42E-02	-2.41E-01
Bladder cancer	2C94	Bladder tissue	6.96E-05	4.48E-01	2.61E+00
Breast cancer	2C60-2C6Z	Breast tissue	9.86E-97	5.84E-01	1.88E+00
Cardioembolic stroke	8B11.20	Whole blood	2.68E-03	-2.30E-01	-9.14E-01
Cervical cancer	2C77	Cervical tissue	2.90E-01	-1.10E-02	-5.81E-02
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	1.30E-01	1.17E-01	4.41E-01
Chronic hepatitis C	1E51.1	Whole blood	9.23E-01	-1.16E-01	-5.14E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	4.94E-02	-1.72E-01	-6.34E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	7.76E-01	-1.01E-01	-3.19E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	5.02E-02	2.62E-01	1.49E+00
Colon cancer	2B90	Colon tissue	6.94E-29	3.50E-01	1.14E+00
Coronary artery disease	BA80-BA8Z	Peripheral blood	5.05E-01	-1.01E-01	-2.95E-01
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	4.83E-01	4.40E-02	8.98E-02
Endometriosis	GA10	Endometrium tissue	6.15E-01	-1.07E-02	-4.24E-02
Familial hypercholesterolemia	5C80.00	Peripheral blood	1.30E-01	-7.05E-02	-3.52E-01
Familial hypercholesterolemia	5C80.00	Whole blood	7.96E-01	8.95E-02	4.95E-01
Gastric cancer	2B72	Gastric tissue	1.88E-01	1.21E-01	4.40E-01
Glioblastopma	2A00.00	Nervous tissue	1.16E-104	-1.42E+00	-1.80E+00
Glioma	2A00.0Y-2A00.0Z	White matter tissue	1.24E-03	5.70E-01	1.31E+00
Head and neck cancer	2D42	Head and neck tissue	9.10E-13	2.74E-01	9.08E-01
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	7.62E-01	1.67E-01	2.45E-01
Huntington's disease	8A01.10	Whole blood	7.36E-01	2.34E-02	7.58E-02
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	8.84E-01	-1.96E-02	-8.38E-02
Immunodeficiency	4A00-4A20	Peripheral blood	3.71E-02	6.75E-02	4.18E-01
Influenza	1.00E+30	Whole blood	8.21E-01	7.96E-02	9.88E-01
Interstitial cystitis	GC00.3	Bladder tissue	7.76E-01	-1.49E-03	-9.41E-03
Intracranial aneurysm	8B01.0	Intracranial artery	9.10E-03	3.09E-01	1.79E+00
Irritable bowel syndrome	DD91.0	Rectal colon tissue	4.46E-02	-2.51E-02	-1.30E-01
Ischemic stroke	8B11	Peripheral blood	9.31E-01	3.62E-02	2.07E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	1.49E-01	5.62E-02	2.49E-01
Lateral sclerosis	8B60.4	Cervical spinal cord	8.57E-02	3.16E-01	1.14E+00
Lateral sclerosis	8B60.4	Skin	8.22E-01	1.92E-02	9.04E-02
Liver cancer	2C12.0	Liver tissue	3.12E-03	-1.75E-01	-5.58E-01
Liver failure	DB99.7-DB99.8	Liver tissue	2.93E-02	-7.13E-01	-1.54E+00
Lung cancer	2C25	Lung tissue	4.10E-26	3.02E-01	9.29E-01
Lupus erythematosus	4A40	Whole blood	1.06E-01	-3.33E-02	-9.15E-02
Major depressive disorder	6A70-6A7Z	Whole blood	1.63E-01	1.28E-02	5.67E-02
Major depressive disorder	6A70-6A7Z	Hippocampus	5.93E-01	-5.42E-03	-2.00E-02
Melanoma	2C30	Skin	5.73E-01	-4.96E-02	-1.11E-01
Multiple myeloma	2A83.1	Bone marrow	7.97E-02	1.37E-01	5.67E-01
Multiple myeloma	2A83.1	Peripheral blood	2.23E-01	-1.99E-01	-7.22E-01
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	7.50E-01	1.38E-01	5.87E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	3.62E-01	-1.60E-01	-4.51E-01
Myelofibrosis	2A20.2	Whole blood	1.90E-04	-8.98E-02	-7.61E-01
Myocardial infarction	BA41-BA50	Peripheral blood	3.29E-01	-6.51E-02	-1.45E-01
Myopathy	8C70.6	Muscle tissue	3.01E-01	-1.32E-02	-9.79E-02
Neonatal sepsis	KA60	Whole blood	8.40E-10	-3.08E-01	-1.07E+00
Neuroectodermal tumour	2A00.11	Brain stem tissue	3.79E-07	3.98E-01	2.42E+00
Non-alcoholic fatty liver disease	DB92	Liver tissue	3.07E-02	-1.20E-01	-7.37E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	9.83E-01	-1.66E-03	-5.54E-03
Olive pollen allergy	CA08.00	Peripheral blood	3.23E-01	2.87E-01	1.01E+00
Oral cancer	2B6E	Oral tissue	9.56E-01	4.68E-02	1.39E-01
Osteoarthritis	FA00-FA0Z	Synovial tissue	3.43E-01	2.15E-02	6.01E-02
Osteoporosis	FB83.1	Bone marrow	4.60E-01	1.35E-01	2.92E-01
Ovarian cancer	2C73	Ovarian tissue	1.51E-01	2.73E-01	6.82E-01
Pancreatic cancer	2C10	Pancreas	2.62E-01	4.78E-02	6.37E-02
Parkinson's disease	8A00.0	Substantia nigra tissue	2.84E-01	-1.12E-01	-2.83E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	1.65E-02	1.35E-01	7.41E-01
Pituitary cancer	2D12	Pituitary tissue	1.58E-02	-2.59E-01	-1.00E+00
Pituitary gonadotrope tumour	2D12	Pituitary tissue	4.71E-01	-3.46E-02	-1.05E-01
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	5.69E-01	1.10E-01	3.89E-01
Polycythemia vera	2A20.4	Whole blood	1.62E-07	-1.33E-01	-9.70E-01
Pompe disease	5C51.3	Biceps muscle	4.37E-01	-5.09E-02	-1.87E-01
Preterm birth	KA21.4Z	Myometrium	6.22E-01	5.69E-02	2.20E-01
Prostate cancer	2C82	Prostate	5.87E-03	1.41E-01	3.17E-01
Psoriasis	EA90	Skin	1.67E-01	-6.47E-03	-1.52E-02
Rectal cancer	2B92	Rectal colon tissue	1.61E-02	2.07E-01	9.17E-01
Renal cancer	2C90-2C91	Kidney	3.41E-01	2.17E-02	1.22E-01
Retinoblastoma	2D02.2	Uvea	5.57E-13	-1.43E+00	-9.74E+00
Rheumatoid arthritis	FA20	Synovial tissue	5.16E-01	4.74E-02	1.37E-01
Rhinovirus infection	CA42.1	Nasal epithelium tissue	6.88E-01	2.21E-02	1.77E-01
Schizophrenia	6A20	Prefrontal cortex	4.79E-02	-1.75E-01	-2.45E-01
Schizophrenia	6A20	Superior temporal cortex	7.52E-01	2.56E-02	8.98E-02
Scleroderma	4A42.Z	Whole blood	2.08E-01	-1.29E-01	-5.93E-01
Seizure	8A60-8A6Z	Whole blood	7.61E-01	5.98E-02	3.58E-01
Sensitive skin	EK0Z	Skin	6.83E-01	4.59E-02	2.36E-01
Sepsis with septic shock	1G41	Whole blood	7.03E-18	-2.46E-01	-9.13E-01
Shwachman-Diamond syndrome	3A70.0	Bone marrow	8.29E-01	-1.26E-02	-6.64E-02
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	1.71E-01	1.30E-01	6.91E-01
Simpson golabi behmel syndrome	LD2C	Adipose tissue	6.63E-01	5.98E-02	2.95E-01
Sjogren's syndrome	4A43.2	Salivary gland tissue	5.46E-01	-7.57E-02	-1.21E+00
Skin cancer	2C30-2C3Z	Skin	1.56E-14	2.98E-01	7.26E-01
Thrombocythemia	3B63	Whole blood	6.15E-06	-1.44E-01	-1.10E+00
Thrombocytopenia	3B64	Whole blood	2.62E-01	6.13E-01	1.26E+00
Thyroid cancer	2D10	Thyroid	3.10E-12	1.58E-01	6.74E-01
Tibial muscular dystrophy	8C75	Muscle tissue	3.56E-01	-4.39E-02	-1.93E-01
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	1.18E-02	-1.01E+00	-7.78E+00
Type 2 diabetes	5A11	Liver tissue	2.25E-01	-5.73E-02	-2.49E-01
Ureter cancer	2C92	Urothelium	8.11E-01	6.12E-02	2.72E-01
Uterine cancer	2C78	Endometrium tissue	7.43E-06	-1.56E-01	-2.84E-01
Vitiligo	ED63.0	Skin	7.45E-01	1.06E-02	3.78E-02