Details of the Drug-Related molecule(s) Expression Atlas

General Information of DTP (ID: DTKLMH6)

• DTP Name: Cystine/glutamate transporter (SLC7A11) DTP Info
• Gene Name: SLC7A11

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	1.86E-07	1.49E-01	4.12E-01
Adrenocortical carcinoma	2D11.Z	Kidney	7.51E-06	9.15E-02	4.72E-01
Alopecia	ED70	Skin from scalp	1.34E-10	-1.17E+00	-1.62E+00
Alzheimer's disease	8A20	Entorhinal cortex	6.50E-05	2.48E-01	3.25E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	1.32E-01	-5.23E-01	-8.58E-01
Aortic stenosis	BB70	Calcified aortic valve	4.87E-01	1.45E-01	2.72E-01
Apnea	7A40	Hyperplastic tonsil	6.35E-02	-4.63E-01	-6.67E-01
Arthropathy	FA00-FA5Z	Peripheral blood	2.36E-01	6.09E-02	3.79E-01
Asthma	CA23	Nasal and bronchial airway	2.63E-07	1.43E+00	1.02E+00
Atopic dermatitis	EA80	Skin	3.17E-01	-2.70E-02	-1.16E-01
Autism	6A02	Whole blood	4.51E-01	-5.51E-02	-2.99E-01
Autoimmune uveitis	9A96	Peripheral monocyte	5.53E-01	5.32E-02	7.26E-02
Autosomal dominant monocytopenia	4B04	Whole blood	1.95E-01	2.47E+00	1.76E+00
Bacterial infection of gingival	1C1H	Gingival tissue	4.08E-10	8.33E-01	1.12E+00
Batten disease	5C56.1	Whole blood	7.83E-01	-8.20E-02	-6.00E-01
Behcet's disease	4A62	Peripheral blood	3.59E-01	-1.34E-01	-5.56E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	1.90E-01	3.02E-01	6.48E-01
Bladder cancer	2C94	Bladder tissue	6.20E-03	3.85E-01	8.97E-01
Breast cancer	2C60-2C6Z	Breast tissue	5.24E-106	4.00E-01	1.69E+00
Cardioembolic stroke	8B11.20	Whole blood	1.40E-05	5.51E-01	1.22E+00
Cervical cancer	2C77	Cervical tissue	9.34E-01	-1.63E-01	-4.94E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	5.01E-01	-3.01E-02	-1.17E-01
Chronic hepatitis C	1E51.1	Whole blood	7.44E-01	4.98E-02	9.95E-02
Chronic obstructive pulmonary disease	CA22	Lung tissue	1.05E-01	2.68E-01	4.47E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	4.45E-06	2.61E+00	1.51E+00
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	1.24E-01	3.04E-01	2.67E+00
Colon cancer	2B90	Colon tissue	7.51E-84	1.88E+00	2.77E+00
Coronary artery disease	BA80-BA8Z	Peripheral blood	3.55E-01	-6.11E-02	-1.49E-01
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	2.75E-01	-5.88E-01	-7.22E-01
Endometriosis	GA10	Endometrium tissue	8.48E-01	1.94E-01	9.41E-02
Familial hypercholesterolemia	5C80.00	Peripheral blood	5.42E-01	-5.76E-02	-4.14E-01
Familial hypercholesterolemia	5C80.00	Whole blood	1.14E-02	-1.56E-01	-8.97E-01
Gastric cancer	2B72	Gastric tissue	8.67E-01	-5.88E-01	-2.96E-01
Glioblastopma	2A00.00	Nervous tissue	3.57E-01	8.51E-02	9.16E-02
Glioma	2A00.0Y-2A00.0Z	White matter tissue	6.79E-01	4.88E-01	4.18E-01
Head and neck cancer	2D42	Head and neck tissue	6.96E-10	1.42E+00	9.56E-01
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	3.35E-01	1.54E-01	4.15E-01
Huntington's disease	8A01.10	Whole blood	1.93E-01	-9.48E-02	-7.99E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	9.01E-03	-2.64E+00	-2.14E+00
Immunodeficiency	4A00-4A20	Peripheral blood	4.37E-02	2.39E-01	1.87E+00
Influenza	1.00E+30	Whole blood	1.41E-02	-2.15E+00	-3.47E+00
Interstitial cystitis	GC00.3	Bladder tissue	1.38E-02	7.96E-01	2.64E+00
Intracranial aneurysm	8B01.0	Intracranial artery	3.13E-05	3.31E+00	1.62E+01
Irritable bowel syndrome	DD91.0	Rectal colon tissue	4.56E-01	-8.02E-03	-2.14E-02
Ischemic stroke	8B11	Peripheral blood	5.92E-01	-2.12E-02	-1.84E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	6.88E-01	1.09E-02	4.24E-02
Lateral sclerosis	8B60.4	Cervical spinal cord	8.35E-01	2.99E-01	2.89E-01
Lateral sclerosis	8B60.4	Skin	5.21E-01	-8.52E-01	-5.69E-01
Liver cancer	2C12.0	Liver tissue	5.61E-49	9.56E-01	4.79E+00
Liver failure	DB99.7-DB99.8	Liver tissue	9.17E-03	4.67E-01	2.07E+00
Lung cancer	2C25	Lung tissue	4.20E-53	1.09E+00	1.19E+00
Lupus erythematosus	4A40	Whole blood	7.87E-01	3.53E-02	5.92E-02
Major depressive disorder	6A70-6A7Z	Whole blood	4.44E-03	1.47E-01	5.25E-01
Major depressive disorder	6A70-6A7Z	Hippocampus	1.30E-01	-1.07E-01	-2.32E-01
Melanoma	2C30	Skin	9.32E-01	3.71E-01	1.88E-01
Multiple myeloma	2A83.1	Bone marrow	1.97E-07	3.33E-01	2.53E+00
Multiple myeloma	2A83.1	Peripheral blood	8.53E-01	-5.40E-01	-6.08E-01
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	6.01E-01	1.99E-01	5.69E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	9.68E-01	5.60E-02	2.87E-01
Myelofibrosis	2A20.2	Whole blood	4.55E-01	-8.73E-02	-8.87E-01
Myocardial infarction	BA41-BA50	Peripheral blood	3.71E-01	1.36E-01	2.84E-01
Myopathy	8C70.6	Muscle tissue	1.20E-02	1.35E-01	1.15E+00
Neonatal sepsis	KA60	Whole blood	6.16E-06	9.44E-02	4.62E-01
Neuroectodermal tumour	2A00.11	Brain stem tissue	4.45E-14	-2.55E+00	-5.89E+00
Non-alcoholic fatty liver disease	DB92	Liver tissue	6.93E-01	-2.32E-02	-1.94E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	7.93E-01	-1.70E-01	-2.09E-01
Olive pollen allergy	CA08.00	Peripheral blood	3.55E-02	-1.09E+00	-1.97E+00
Oral cancer	2B6E	Oral tissue	1.79E-03	8.13E-01	6.15E-01
Osteoarthritis	FA00-FA0Z	Synovial tissue	5.27E-01	-3.85E-02	-1.76E-02
Osteoporosis	FB83.1	Bone marrow	7.26E-01	-7.36E-01	-7.11E-01
Ovarian cancer	2C73	Ovarian tissue	2.27E-01	2.63E-01	2.09E-01
Pancreatic cancer	2C10	Pancreas	6.61E-11	8.94E-01	2.29E+00
Parkinson's disease	8A00.0	Substantia nigra tissue	2.84E-01	-1.03E-01	-1.60E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	1.03E-01	8.02E-02	6.13E-01
Pituitary cancer	2D12	Pituitary tissue	3.31E-02	2.38E-01	5.72E-01
Pituitary gonadotrope tumour	2D12	Pituitary tissue	4.77E-02	4.05E-01	9.61E-01
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	6.65E-01	1.83E-02	1.56E-01
Polycythemia vera	2A20.4	Whole blood	3.82E-05	9.00E-02	8.00E-01
Pompe disease	5C51.3	Biceps muscle	9.21E-01	8.13E-02	1.56E-01
Preterm birth	KA21.4Z	Myometrium	9.70E-01	6.74E-02	4.00E-01
Prostate cancer	2C82	Prostate	2.46E-02	3.80E-01	4.28E-01
Psoriasis	EA90	Skin	4.15E-36	1.23E+00	2.15E+00
Rectal cancer	2B92	Rectal colon tissue	2.33E-04	1.52E+00	2.97E+00
Renal cancer	2C90-2C91	Kidney	4.79E-11	6.62E-01	2.11E+00
Retinoblastoma	2D02.2	Uvea	4.98E-04	-1.25E+00	-3.11E+00
Rheumatoid arthritis	FA20	Synovial tissue	4.16E-04	3.53E-02	1.40E-01
Rhinovirus infection	CA42.1	Nasal epithelium tissue	1.32E-01	-9.45E-02	-1.68E-01
Schizophrenia	6A20	Prefrontal cortex	2.22E-01	-1.85E-01	-1.12E-01
Schizophrenia	6A20	Superior temporal cortex	9.72E-01	1.31E-01	3.09E-01
Scleroderma	4A42.Z	Whole blood	3.80E-02	1.50E-01	7.80E-01
Seizure	8A60-8A6Z	Whole blood	8.61E-01	-2.09E-02	-4.87E-02
Sensitive skin	EK0Z	Skin	7.04E-02	1.85E-01	1.15E+00
Sepsis with septic shock	1G41	Whole blood	6.42E-26	2.36E-01	9.65E-01
Shwachman-Diamond syndrome	3A70.0	Bone marrow	2.95E-01	8.40E-03	2.43E-02
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	1.93E-02	2.13E-01	1.46E+00
Simpson golabi behmel syndrome	LD2C	Adipose tissue	3.49E-01	1.06E+00	7.95E-01
Sjogren's syndrome	4A43.2	Salivary gland tissue	6.26E-01	4.79E-02	1.22E-01
Skin cancer	2C30-2C3Z	Skin	3.27E-28	6.65E-01	1.21E+00
Thrombocythemia	3B63	Whole blood	9.66E-02	8.15E-02	8.53E-01
Thrombocytopenia	3B64	Whole blood	2.75E-01	-3.15E-02	-1.35E-01
Thyroid cancer	2D10	Thyroid	3.71E-02	-2.14E-01	-2.78E-01
Tibial muscular dystrophy	8C75	Muscle tissue	7.71E-01	-4.42E-02	-3.09E-01
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	6.85E-02	6.76E-01	1.31E+00
Type 2 diabetes	5A11	Liver tissue	3.89E-02	7.36E-02	1.24E+00
Ureter cancer	2C92	Urothelium	2.18E-01	-2.72E-02	-8.55E-02
Uterine cancer	2C78	Endometrium tissue	4.52E-23	3.78E-01	1.01E+00
Vitiligo	ED63.0	Skin	7.84E-01	-1.13E-02	-1.23E-02