Details of the Drug-Related molecule(s) Expression Atlas

General Information of DTP (ID: DTKXTPW)

• DTP Name: Sodium/dicarboxylate cotransporter 3 (SLC13A3) DTP Info
• Gene Name: NADC3

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	1.75E-02	1.05E-02	5.37E-02
Adrenocortical carcinoma	2D11.Z	Kidney	1.51E-01	1.63E-02	7.14E-02
Alopecia	ED70	Skin from scalp	1.47E-01	-6.01E-02	-3.80E-01
Alzheimer's disease	8A20	Entorhinal cortex	4.60E-01	4.14E-02	1.37E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	2.49E-01	-8.08E-02	-8.80E-01
Aortic stenosis	BB70	Calcified aortic valve	8.11E-01	2.97E-03	6.27E-03
Apnea	7A40	Hyperplastic tonsil	5.15E-01	-2.34E-02	-7.34E-02
Arthropathy	FA00-FA5Z	Peripheral blood	7.40E-01	4.47E-02	3.78E-01
Asthma	CA23	Nasal and bronchial airway	3.06E-02	-1.12E-01	-2.06E-01
Atopic dermatitis	EA80	Skin	9.31E-02	3.26E-02	3.49E-01
Autism	6A02	Whole blood	1.78E-02	-1.22E-01	-7.05E-01
Autoimmune uveitis	9A96	Peripheral monocyte	9.02E-02	-3.08E-01	-2.21E+00
Autosomal dominant monocytopenia	4B04	Whole blood	6.00E-01	3.21E-02	2.71E-01
Bacterial infection of gingival	1C1H	Gingival tissue	1.38E-01	-5.48E-02	-2.51E-01
Batten disease	5C56.1	Whole blood	5.79E-01	-5.57E-03	-6.56E-02
Behcet's disease	4A62	Peripheral blood	8.94E-03	1.63E-01	1.32E+00
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	3.59E-02	1.41E-01	1.01E+00
Bladder cancer	2C94	Bladder tissue	1.68E-05	7.98E-01	3.95E+00
Breast cancer	2C60-2C6Z	Breast tissue	8.46E-02	2.44E-02	6.70E-02
Cardioembolic stroke	8B11.20	Whole blood	5.09E-02	5.89E-02	4.06E-01
Cervical cancer	2C77	Cervical tissue	9.15E-01	3.55E-02	1.50E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	4.06E-01	-1.30E-02	-6.65E-02
Chronic hepatitis C	1E51.1	Whole blood	2.31E-01	7.58E-02	6.71E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	3.40E-01	4.08E-02	3.03E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	2.67E-02	-1.48E-01	-2.40E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	9.99E-03	-2.50E-01	-1.22E+00
Colon cancer	2B90	Colon tissue	2.90E-51	2.89E-01	1.32E+00
Coronary artery disease	BA80-BA8Z	Peripheral blood	6.33E-01	-6.89E-02	-5.91E-01
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	4.50E-01	-7.83E-02	-5.11E-01
Endometriosis	GA10	Endometrium tissue	5.02E-02	1.37E-01	5.93E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	7.72E-01	-2.67E-02	-2.46E-01
Familial hypercholesterolemia	5C80.00	Whole blood	1.75E-02	-1.61E-01	-7.64E-01
Gastric cancer	2B72	Gastric tissue	3.17E-02	-2.95E-01	-3.77E+00
Glioblastopma	2A00.00	Nervous tissue	1.52E-24	-2.10E-01	-6.41E-01
Glioma	2A00.0Y-2A00.0Z	White matter tissue	1.26E-03	-4.81E-01	-1.24E+00
Head and neck cancer	2D42	Head and neck tissue	4.16E-11	-1.82E-01	-2.18E-01
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	9.19E-01	-6.21E-02	-3.24E-01
Huntington's disease	8A01.10	Whole blood	1.14E-01	6.89E-02	8.48E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	7.83E-01	2.04E-02	1.12E-01
Immunodeficiency	4A00-4A20	Peripheral blood	1.65E-01	1.44E-01	1.08E+00
Influenza	1.00E+30	Whole blood	1.90E-02	2.38E-01	2.60E+00
Interstitial cystitis	GC00.3	Bladder tissue	6.85E-02	-6.35E-02	-6.86E-01
Intracranial aneurysm	8B01.0	Intracranial artery	1.94E-01	6.18E-02	5.21E-01
Irritable bowel syndrome	DD91.0	Rectal colon tissue	1.35E-01	4.94E-02	1.63E-01
Ischemic stroke	8B11	Peripheral blood	7.32E-01	1.05E-02	1.32E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	2.08E-02	1.05E-01	6.16E-01
Lateral sclerosis	8B60.4	Cervical spinal cord	5.91E-01	1.25E-01	8.82E-01
Lateral sclerosis	8B60.4	Skin	8.03E-01	-4.79E-02	-3.03E-01
Liver cancer	2C12.0	Liver tissue	7.65E-03	7.12E-03	1.93E-02
Liver failure	DB99.7-DB99.8	Liver tissue	1.25E-03	-7.91E-01	-2.03E+00
Lung cancer	2C25	Lung tissue	6.48E-24	1.61E-01	8.58E-01
Lupus erythematosus	4A40	Whole blood	2.65E-01	-1.58E-01	-3.60E-01
Major depressive disorder	6A70-6A7Z	Whole blood	3.50E-01	3.09E-02	1.50E-01
Major depressive disorder	6A70-6A7Z	Hippocampus	1.52E-01	7.67E-02	5.65E-01
Melanoma	2C30	Skin	3.86E-03	7.39E-01	1.24E+00
Multiple myeloma	2A83.1	Bone marrow	4.80E-05	-4.28E-01	-3.10E+00
Multiple myeloma	2A83.1	Peripheral blood	2.85E-01	4.94E-02	3.49E-01
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	3.49E-01	-1.37E-01	-6.04E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	2.57E-01	-1.02E-01	-3.83E-01
Myelofibrosis	2A20.2	Whole blood	7.14E-02	1.04E-01	7.77E-01
Myocardial infarction	BA41-BA50	Peripheral blood	4.45E-02	1.76E-01	4.89E-01
Myopathy	8C70.6	Muscle tissue	5.32E-01	-2.42E-02	-2.01E-01
Neonatal sepsis	KA60	Whole blood	1.40E-03	-1.34E-01	-5.76E-01
Neuroectodermal tumour	2A00.11	Brain stem tissue	7.37E-07	-9.46E-01	-3.71E+00
Non-alcoholic fatty liver disease	DB92	Liver tissue	8.75E-02	-5.06E-02	-3.78E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	2.95E-01	1.04E-01	8.25E-01
Olive pollen allergy	CA08.00	Peripheral blood	8.64E-02	2.51E-01	1.28E+00
Oral cancer	2B6E	Oral tissue	9.29E-04	-2.34E-01	-6.97E-01
Osteoarthritis	FA00-FA0Z	Synovial tissue	3.99E-01	-2.07E-01	-1.14E+00
Osteoporosis	FB83.1	Bone marrow	8.98E-01	-4.82E-03	-2.97E-02
Ovarian cancer	2C73	Ovarian tissue	2.23E-01	-8.24E-02	-3.97E-01
Pancreatic cancer	2C10	Pancreas	1.16E-01	-1.13E-01	-3.25E-01
Parkinson's disease	8A00.0	Substantia nigra tissue	4.05E-01	1.10E-02	4.55E-02
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	5.61E-02	-3.25E-02	-3.75E-01
Pituitary cancer	2D12	Pituitary tissue	7.77E-01	-4.80E-02	-2.11E-01
Pituitary gonadotrope tumour	2D12	Pituitary tissue	2.66E-01	-8.78E-02	-3.59E-01
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	4.37E-02	1.02E-01	1.19E+00
Polycythemia vera	2A20.4	Whole blood	3.46E-09	1.77E-01	1.66E+00
Pompe disease	5C51.3	Biceps muscle	5.47E-01	5.31E-03	8.09E-02
Preterm birth	KA21.4Z	Myometrium	4.53E-01	4.67E-02	4.49E-01
Prostate cancer	2C82	Prostate	2.39E-01	1.74E-01	2.94E-01
Psoriasis	EA90	Skin	1.24E-02	-5.60E-02	-2.11E-01
Rectal cancer	2B92	Rectal colon tissue	4.18E-04	2.24E-01	1.81E+00
Renal cancer	2C90-2C91	Kidney	1.02E-02	-9.78E-01	-9.18E-01
Retinoblastoma	2D02.2	Uvea	3.47E-01	2.60E-03	2.54E-02
Rheumatoid arthritis	FA20	Synovial tissue	5.53E-02	-5.96E-02	-3.98E-01
Rhinovirus infection	CA42.1	Nasal epithelium tissue	2.19E-01	-1.42E-01	-3.93E-01
Schizophrenia	6A20	Prefrontal cortex	3.61E-01	-3.71E-02	-1.43E-01
Schizophrenia	6A20	Superior temporal cortex	6.99E-02	-2.87E-02	-2.45E-01
Scleroderma	4A42.Z	Whole blood	3.09E-01	6.42E-02	8.14E-01
Seizure	8A60-8A6Z	Whole blood	2.01E-01	4.60E-02	3.96E-01
Sensitive skin	EK0Z	Skin	8.02E-01	-5.02E-02	-4.36E-01
Sepsis with septic shock	1G41	Whole blood	8.67E-02	-3.85E-02	-1.72E-01
Shwachman-Diamond syndrome	3A70.0	Bone marrow	7.23E-02	6.96E-01	1.51E+00
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	1.24E-01	1.06E-01	7.71E-01
Simpson golabi behmel syndrome	LD2C	Adipose tissue	5.63E-01	-1.30E-02	-5.61E-01
Sjogren's syndrome	4A43.2	Salivary gland tissue	6.93E-01	-2.10E-01	-1.29E+00
Skin cancer	2C30-2C3Z	Skin	2.23E-16	2.67E-01	8.85E-01
Thrombocythemia	3B63	Whole blood	7.36E-03	6.69E-02	5.25E-01
Thrombocytopenia	3B64	Whole blood	4.87E-01	-6.70E-02	-3.67E-01
Thyroid cancer	2D10	Thyroid	3.17E-08	9.94E-02	5.64E-01
Tibial muscular dystrophy	8C75	Muscle tissue	5.27E-02	-1.06E-01	-6.49E-01
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	2.51E-01	2.07E-01	1.22E+00
Type 2 diabetes	5A11	Liver tissue	5.92E-01	7.04E-02	3.33E-01
Ureter cancer	2C92	Urothelium	5.55E-01	-2.21E-02	-1.73E-01
Uterine cancer	2C78	Endometrium tissue	1.82E-03	-9.71E-02	-4.10E-01
Vitiligo	ED63.0	Skin	1.88E-01	-3.97E-02	-2.99E-01