Details of the Drug-Related molecule(s) Expression Atlas

General Information of DTP (ID: DTM953D)

• DTP Name: Vesicular amine transporter 1 (SLC18A1) DTP Info
• Gene Name: VMAT1

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	9.66E-01	1.92E-02	1.16E-01
Adrenocortical carcinoma	2D11.Z	Kidney	1.27E-02	-7.01E-01	-5.12E-01
Alopecia	ED70	Skin from scalp	1.05E-03	-3.80E-01	-8.45E-01
Alzheimer's disease	8A20	Entorhinal cortex	2.65E-02	-4.30E-02	-2.34E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	1.96E-01	-2.23E-02	-2.71E-01
Aortic stenosis	BB70	Calcified aortic valve	5.55E-01	1.50E-01	3.52E-01
Apnea	7A40	Hyperplastic tonsil	4.95E-01	7.51E-02	2.25E-01
Arthropathy	FA00-FA5Z	Peripheral blood	2.56E-01	-1.18E-01	-9.87E-01
Asthma	CA23	Nasal and bronchial airway	7.23E-01	-4.41E-02	-1.12E-01
Atopic dermatitis	EA80	Skin	5.41E-02	1.71E-02	1.46E-01
Autism	6A02	Whole blood	8.30E-01	7.88E-02	3.46E-01
Autoimmune uveitis	9A96	Peripheral monocyte	1.21E-01	1.59E-01	9.70E-01
Autosomal dominant monocytopenia	4B04	Whole blood	1.38E-01	-9.79E-02	-1.04E+00
Bacterial infection of gingival	1C1H	Gingival tissue	4.89E-01	2.43E-02	9.77E-02
Batten disease	5C56.1	Whole blood	9.28E-01	8.70E-03	4.64E-02
Behcet's disease	4A62	Peripheral blood	2.16E-01	1.14E-01	6.50E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	6.03E-01	8.58E-03	6.11E-02
Bladder cancer	2C94	Bladder tissue	1.33E-02	8.61E-01	1.73E+00
Breast cancer	2C60-2C6Z	Breast tissue	6.86E-13	-1.42E-01	-3.60E-01
Cardioembolic stroke	8B11.20	Whole blood	1.26E-01	-2.61E-01	-5.98E-01
Cervical cancer	2C77	Cervical tissue	7.61E-01	8.49E-02	1.73E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	2.16E-01	-8.17E-02	-4.26E-01
Chronic hepatitis C	1E51.1	Whole blood	3.24E-01	5.63E-02	4.29E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	9.83E-03	1.08E-01	5.51E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	1.31E-01	3.99E-02	2.59E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	8.46E-01	-5.65E-02	-4.07E-01
Colon cancer	2B90	Colon tissue	3.05E-12	-4.26E-01	-9.82E-01
Coronary artery disease	BA80-BA8Z	Peripheral blood	4.64E-02	1.64E-01	1.37E+00
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	2.81E-01	-3.48E-02	-1.84E-01
Endometriosis	GA10	Endometrium tissue	3.84E-01	1.37E-01	4.98E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	7.23E-01	3.01E-02	1.55E-01
Familial hypercholesterolemia	5C80.00	Whole blood	1.40E-02	-1.36E-01	-5.01E-01
Gastric cancer	2B72	Gastric tissue	4.36E-01	-4.04E-01	-1.82E+00
Glioblastopma	2A00.00	Nervous tissue	3.32E-01	-7.49E-02	-2.34E-01
Glioma	2A00.0Y-2A00.0Z	White matter tissue	8.09E-02	-3.56E-01	-7.50E-01
Head and neck cancer	2D42	Head and neck tissue	9.64E-01	1.12E-02	6.43E-02
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	4.15E-02	-1.38E-01	-3.54E-01
Huntington's disease	8A01.10	Whole blood	4.53E-01	-2.49E-03	-2.56E-02
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	9.53E-01	1.03E-02	7.99E-02
Immunodeficiency	4A00-4A20	Peripheral blood	2.71E-01	3.47E-02	2.63E-01
Influenza	1.00E+30	Whole blood	4.89E-04	3.13E-01	1.09E+01
Interstitial cystitis	GC00.3	Bladder tissue	1.05E-01	1.13E-01	9.70E-01
Intracranial aneurysm	8B01.0	Intracranial artery	3.42E-01	-7.29E-02	-5.12E-01
Irritable bowel syndrome	DD91.0	Rectal colon tissue	3.05E-01	-9.71E-02	-2.65E-01
Ischemic stroke	8B11	Peripheral blood	9.01E-01	1.43E-02	6.70E-02
Juvenile idiopathic arthritis	FA24	Peripheral blood	4.13E-01	-2.90E-02	-6.87E-02
Lateral sclerosis	8B60.4	Cervical spinal cord	2.05E-01	1.70E-01	8.34E-01
Lateral sclerosis	8B60.4	Skin	8.67E-01	-4.75E-02	-2.86E-01
Liver cancer	2C12.0	Liver tissue	1.93E-03	-8.93E-02	-5.04E-01
Liver failure	DB99.7-DB99.8	Liver tissue	3.59E-01	-9.97E-02	-3.97E-01
Lung cancer	2C25	Lung tissue	5.38E-05	-4.84E-02	-2.56E-01
Lupus erythematosus	4A40	Whole blood	3.98E-02	5.85E-02	2.26E-01
Major depressive disorder	6A70-6A7Z	Whole blood	3.87E-01	6.21E-03	1.46E-02
Major depressive disorder	6A70-6A7Z	Hippocampus	8.50E-01	2.79E-03	1.97E-02
Melanoma	2C30	Skin	4.37E-01	1.53E-01	3.13E-01
Multiple myeloma	2A83.1	Bone marrow	6.98E-04	-1.13E+00	-2.39E+00
Multiple myeloma	2A83.1	Peripheral blood	1.83E-01	1.18E-01	6.43E-01
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	3.06E-01	-2.04E-01	-7.90E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	6.53E-01	-9.63E-03	-5.04E-02
Myelofibrosis	2A20.2	Whole blood	1.38E-02	9.42E-02	6.15E-01
Myocardial infarction	BA41-BA50	Peripheral blood	4.87E-01	1.14E-01	1.71E-01
Myopathy	8C70.6	Muscle tissue	7.41E-01	-5.00E-02	-2.12E-01
Neonatal sepsis	KA60	Whole blood	9.19E-01	-4.52E-02	-1.76E-01
Neuroectodermal tumour	2A00.11	Brain stem tissue	2.88E-03	-7.31E-01	-1.84E+00
Non-alcoholic fatty liver disease	DB92	Liver tissue	4.70E-01	8.73E-03	5.92E-02
Obesity related type 2 diabetes	5A11	Omental adipose tissue	1.72E-01	6.40E-02	1.08E+00
Olive pollen allergy	CA08.00	Peripheral blood	1.09E-02	1.12E-01	1.72E+00
Oral cancer	2B6E	Oral tissue	5.61E-04	-3.50E-01	-8.85E-01
Osteoarthritis	FA00-FA0Z	Synovial tissue	5.57E-03	-2.92E-01	-1.15E+00
Osteoporosis	FB83.1	Bone marrow	2.16E-01	2.26E-01	3.83E+00
Ovarian cancer	2C73	Ovarian tissue	6.42E-01	-2.38E-02	-1.12E-01
Pancreatic cancer	2C10	Pancreas	1.10E-01	-2.83E-01	-1.01E+00
Parkinson's disease	8A00.0	Substantia nigra tissue	2.09E-01	-1.66E-01	-3.68E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	1.94E-01	6.55E-02	4.25E-01
Pituitary cancer	2D12	Pituitary tissue	4.80E-03	2.02E-01	7.55E-01
Pituitary gonadotrope tumour	2D12	Pituitary tissue	9.05E-01	-5.21E-02	-1.93E-01
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	2.44E-01	-1.58E-01	-7.48E-01
Polycythemia vera	2A20.4	Whole blood	4.27E-07	2.01E-01	1.15E+00
Pompe disease	5C51.3	Biceps muscle	1.30E-01	-2.80E-02	-1.16E-01
Preterm birth	KA21.4Z	Myometrium	7.04E-01	6.42E-02	2.51E-01
Prostate cancer	2C82	Prostate	5.33E-01	-1.05E-01	-2.63E-01
Psoriasis	EA90	Skin	4.54E-02	-5.06E-02	-1.80E-01
Rectal cancer	2B92	Rectal colon tissue	4.53E-02	-7.16E-01	-1.62E+00
Renal cancer	2C90-2C91	Kidney	1.98E-03	-3.21E-01	-1.09E+00
Retinoblastoma	2D02.2	Uvea	3.60E-03	-2.28E-01	-3.01E+00
Rheumatoid arthritis	FA20	Synovial tissue	8.58E-02	-1.07E-01	-3.90E-01
Rhinovirus infection	CA42.1	Nasal epithelium tissue	7.59E-01	-9.72E-03	-7.02E-02
Schizophrenia	6A20	Prefrontal cortex	3.96E-01	7.42E-03	2.16E-02
Schizophrenia	6A20	Superior temporal cortex	4.03E-01	-5.12E-02	-4.64E-01
Scleroderma	4A42.Z	Whole blood	1.39E-03	1.93E-01	2.00E+00
Seizure	8A60-8A6Z	Whole blood	1.52E-01	-1.57E-02	-1.21E-01
Sensitive skin	EK0Z	Skin	8.03E-01	3.41E-03	1.46E-02
Sepsis with septic shock	1G41	Whole blood	9.93E-01	-7.46E-02	-2.54E-01
Shwachman-Diamond syndrome	3A70.0	Bone marrow	1.90E-01	1.88E-01	7.39E-01
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	6.97E-01	1.90E-02	9.79E-02
Simpson golabi behmel syndrome	LD2C	Adipose tissue	7.86E-01	-1.00E-01	-5.08E-01
Sjogren's syndrome	4A43.2	Salivary gland tissue	5.26E-01	1.36E-01	1.02E+00
Skin cancer	2C30-2C3Z	Skin	5.16E-09	5.73E-02	1.79E-01
Thrombocythemia	3B63	Whole blood	1.05E-05	1.53E-01	1.00E+00
Thrombocytopenia	3B64	Whole blood	2.25E-01	9.58E-02	5.42E-01
Thyroid cancer	2D10	Thyroid	1.72E-01	-1.63E-04	-8.72E-04
Tibial muscular dystrophy	8C75	Muscle tissue	5.04E-01	8.94E-04	5.79E-03
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	5.66E-01	1.15E-01	1.10E+00
Type 2 diabetes	5A11	Liver tissue	4.61E-01	1.11E-01	7.67E-01
Ureter cancer	2C92	Urothelium	2.69E-01	-5.71E-02	-3.74E-01
Uterine cancer	2C78	Endometrium tissue	6.58E-01	4.38E-02	1.24E-01
Vitiligo	ED63.0	Skin	1.32E-01	-2.35E-01	-9.70E-01