Details of the Drug-Related molecule(s) Expression Atlas

General Information of DTP (ID: DTO4FLB)

• DTP Name: Sodium/glucose cotransporter 3 (SLC5A4) DTP Info
• Gene Name: SGLT3

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	6.29E-03	-3.83E-02	-1.80E-01
Adrenocortical carcinoma	2D11.Z	Kidney	5.16E-01	1.00E-02	3.76E-02
Alopecia	ED70	Skin from scalp	4.84E-01	5.15E-02	3.09E-01
Alzheimer's disease	8A20	Entorhinal cortex	2.32E-01	-1.04E-02	-5.65E-02
Ankylosing spondylitis	FA92.0	Pheripheral blood	9.91E-01	5.26E-03	6.64E-02
Aortic stenosis	BB70	Calcified aortic valve	5.39E-01	9.74E-02	1.56E-01
Apnea	7A40	Hyperplastic tonsil	5.98E-01	8.04E-02	4.26E-01
Arthropathy	FA00-FA5Z	Peripheral blood	8.31E-01	-1.54E-02	-1.23E-01
Asthma	CA23	Nasal and bronchial airway	1.16E-01	-5.94E-02	-1.72E-01
Atopic dermatitis	EA80	Skin	1.60E-01	-6.04E-02	-4.42E-01
Autism	6A02	Whole blood	5.05E-01	-4.08E-02	-2.17E-01
Autoimmune uveitis	9A96	Peripheral monocyte	9.90E-03	-1.15E-01	-8.00E-01
Autosomal dominant monocytopenia	4B04	Whole blood	1.91E-01	7.26E-02	4.64E-01
Bacterial infection of gingival	1C1H	Gingival tissue	3.30E-01	3.27E-02	1.25E-01
Batten disease	5C56.1	Whole blood	3.18E-01	1.14E-01	1.36E+00
Behcet's disease	4A62	Peripheral blood	5.15E-01	4.34E-02	2.63E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	1.85E-03	-9.73E-02	-6.89E-01
Bladder cancer	2C94	Bladder tissue	7.23E-05	6.06E-01	3.51E+00
Breast cancer	2C60-2C6Z	Breast tissue	2.04E-07	-8.69E-02	-2.48E-01
Cardioembolic stroke	8B11.20	Whole blood	3.36E-02	1.39E-01	5.78E-01
Cervical cancer	2C77	Cervical tissue	5.90E-01	3.37E-03	1.41E-02
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	7.53E-01	-4.19E-03	-2.15E-02
Chronic hepatitis C	1E51.1	Whole blood	1.78E-01	8.33E-02	4.91E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	3.18E-01	4.47E-02	1.78E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	8.18E-01	-8.13E-03	-5.02E-02
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	1.46E-02	1.58E-01	1.15E+00
Colon cancer	2B90	Colon tissue	4.13E-01	7.46E-03	3.96E-02
Coronary artery disease	BA80-BA8Z	Peripheral blood	3.51E-03	1.24E-01	3.14E+00
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	5.39E-01	-4.03E-02	-1.84E-01
Endometriosis	GA10	Endometrium tissue	2.39E-01	9.74E-02	5.11E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	6.66E-01	-1.93E-02	-1.21E-01
Familial hypercholesterolemia	5C80.00	Whole blood	4.72E-05	-2.15E-01	-1.02E+00
Gastric cancer	2B72	Gastric tissue	6.01E-01	2.16E-02	3.25E-01
Glioblastopma	2A00.00	Nervous tissue	2.42E-04	-5.54E-02	-1.92E-01
Glioma	2A00.0Y-2A00.0Z	White matter tissue	7.35E-03	-4.77E-01	-1.37E+00
Head and neck cancer	2D42	Head and neck tissue	8.65E-01	-5.22E-04	-3.17E-03
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	3.72E-01	-5.10E-03	-2.13E-02
Huntington's disease	8A01.10	Whole blood	6.18E-01	5.97E-03	3.66E-02
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	9.47E-01	9.76E-02	3.97E-01
Immunodeficiency	4A00-4A20	Peripheral blood	5.73E-01	2.45E-02	3.38E-01
Influenza	1.00E+30	Whole blood	3.06E-01	3.50E-01	1.37E+00
Interstitial cystitis	GC00.3	Bladder tissue	2.88E-01	1.41E-02	8.25E-02
Intracranial aneurysm	8B01.0	Intracranial artery	8.31E-02	-7.27E-02	-5.70E-01
Irritable bowel syndrome	DD91.0	Rectal colon tissue	2.65E-01	8.29E-02	2.58E-01
Ischemic stroke	8B11	Peripheral blood	8.92E-01	3.77E-02	2.42E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	1.53E-01	9.90E-02	3.31E-01
Lateral sclerosis	8B60.4	Cervical spinal cord	7.17E-01	1.41E-01	5.26E-01
Lateral sclerosis	8B60.4	Skin	4.38E-01	5.87E-02	2.96E-01
Liver cancer	2C12.0	Liver tissue	1.42E-05	-1.21E-01	-6.47E-01
Liver failure	DB99.7-DB99.8	Liver tissue	7.33E-02	-8.65E-02	-8.15E-01
Lung cancer	2C25	Lung tissue	6.28E-05	-7.53E-02	-3.33E-01
Lupus erythematosus	4A40	Whole blood	7.07E-01	-1.05E-02	-2.96E-02
Major depressive disorder	6A70-6A7Z	Whole blood	3.81E-02	8.51E-02	4.50E-01
Major depressive disorder	6A70-6A7Z	Hippocampus	8.00E-01	3.01E-02	2.20E-01
Melanoma	2C30	Skin	8.55E-03	4.20E-01	7.68E-01
Multiple myeloma	2A83.1	Bone marrow	1.54E-05	-5.05E-01	-3.64E+00
Multiple myeloma	2A83.1	Peripheral blood	6.33E-01	-1.24E-02	-6.96E-02
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	7.54E-01	-4.85E-03	-2.11E-02
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	9.77E-01	3.80E-02	2.31E-01
Myelofibrosis	2A20.2	Whole blood	3.19E-01	-3.08E-02	-2.10E-01
Myocardial infarction	BA41-BA50	Peripheral blood	8.34E-01	5.99E-02	1.44E-01
Myopathy	8C70.6	Muscle tissue	7.43E-02	1.08E-01	8.80E-01
Neonatal sepsis	KA60	Whole blood	2.13E-03	9.94E-02	5.12E-01
Neuroectodermal tumour	2A00.11	Brain stem tissue	5.00E-04	-8.31E-01	-1.61E+00
Non-alcoholic fatty liver disease	DB92	Liver tissue	4.87E-01	-8.53E-02	-6.07E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	9.27E-03	1.00E-01	1.44E+00
Olive pollen allergy	CA08.00	Peripheral blood	2.29E-02	1.49E-01	1.43E+00
Oral cancer	2B6E	Oral tissue	8.94E-02	-1.52E-01	-6.43E-01
Osteoarthritis	FA00-FA0Z	Synovial tissue	3.75E-01	1.31E-01	7.89E-01
Osteoporosis	FB83.1	Bone marrow	2.21E-01	1.07E-01	8.72E-01
Ovarian cancer	2C73	Ovarian tissue	2.95E-01	-2.40E-01	-5.98E-01
Pancreatic cancer	2C10	Pancreas	3.13E-02	-2.09E-01	-6.52E-01
Parkinson's disease	8A00.0	Substantia nigra tissue	3.77E-01	-1.65E-02	-8.35E-02
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	1.42E-01	8.78E-02	5.07E-01
Pituitary cancer	2D12	Pituitary tissue	5.72E-01	9.06E-02	3.49E-01
Pituitary gonadotrope tumour	2D12	Pituitary tissue	4.20E-01	5.52E-02	2.01E-01
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	1.69E-01	5.74E-02	4.90E-01
Polycythemia vera	2A20.4	Whole blood	4.03E-01	-2.07E-02	-1.43E-01
Pompe disease	5C51.3	Biceps muscle	8.85E-02	-1.68E-01	-8.80E-01
Preterm birth	KA21.4Z	Myometrium	4.43E-01	-7.50E-02	-4.03E-01
Prostate cancer	2C82	Prostate	8.94E-02	-4.44E-01	-7.79E-01
Psoriasis	EA90	Skin	4.38E-08	-2.15E-01	-6.27E-01
Rectal cancer	2B92	Rectal colon tissue	6.57E-03	-3.07E-01	-1.93E+00
Renal cancer	2C90-2C91	Kidney	5.21E-01	-2.57E-02	-9.38E-02
Retinoblastoma	2D02.2	Uvea	8.63E-01	-6.80E-02	-4.17E-01
Rheumatoid arthritis	FA20	Synovial tissue	2.28E-02	3.36E-01	1.27E+00
Rhinovirus infection	CA42.1	Nasal epithelium tissue	4.51E-01	-8.96E-03	-6.55E-02
Schizophrenia	6A20	Prefrontal cortex	5.68E-01	-1.47E-02	-4.65E-02
Schizophrenia	6A20	Superior temporal cortex	5.15E-01	-2.53E-03	-1.74E-02
Scleroderma	4A42.Z	Whole blood	9.88E-01	-1.54E-02	-8.42E-02
Seizure	8A60-8A6Z	Whole blood	8.57E-01	-4.43E-02	-2.19E-01
Sensitive skin	EK0Z	Skin	7.25E-01	2.97E-02	1.32E-01
Sepsis with septic shock	1G41	Whole blood	3.51E-05	7.41E-02	3.72E-01
Shwachman-Diamond syndrome	3A70.0	Bone marrow	2.72E-02	4.67E-01	1.82E+00
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	4.24E-02	3.42E-02	2.73E-01
Simpson golabi behmel syndrome	LD2C	Adipose tissue	5.52E-01	-2.39E-02	-1.71E-01
Sjogren's syndrome	4A43.2	Salivary gland tissue	7.54E-01	-9.15E-02	-4.17E-01
Skin cancer	2C30-2C3Z	Skin	1.27E-07	5.83E-02	1.53E-01
Thrombocythemia	3B63	Whole blood	8.42E-02	-4.42E-02	-3.08E-01
Thrombocytopenia	3B64	Whole blood	5.80E-01	1.77E-01	9.08E-01
Thyroid cancer	2D10	Thyroid	9.81E-01	8.94E-03	3.73E-02
Tibial muscular dystrophy	8C75	Muscle tissue	9.91E-01	-1.66E-02	-7.76E-02
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	4.24E-01	1.83E-02	3.03E-01
Type 2 diabetes	5A11	Liver tissue	2.08E-01	-4.01E-02	-1.95E-01
Ureter cancer	2C92	Urothelium	2.68E-01	-6.23E-02	-3.50E-01
Uterine cancer	2C78	Endometrium tissue	3.07E-06	-1.57E-01	-5.65E-01
Vitiligo	ED63.0	Skin	3.71E-03	-1.38E-01	-1.61E+00