Details of the Drug-Related molecule(s) Expression Atlas

General Information of DTP (ID: DTVP67E)

• DTP Name: Organic anion transporter 3 (SLC22A8) DTP Info
• Gene Name: OAT3

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	5.04E-01	4.29E-03	1.41E-02
Adrenocortical carcinoma	2D11.Z	Kidney	6.97E-02	-1.99E-01	-4.72E-01
Alopecia	ED70	Skin from scalp	3.78E-01	-5.21E-02	-2.30E-01
Alzheimer's disease	8A20	Entorhinal cortex	5.19E-01	-8.88E-03	-2.08E-02
Ankylosing spondylitis	FA92.0	Pheripheral blood	6.66E-01	-1.09E-02	-9.05E-02
Aortic stenosis	BB70	Calcified aortic valve	6.38E-01	-2.30E-01	-3.02E-01
Apnea	7A40	Hyperplastic tonsil	1.90E-01	-6.02E-01	-1.71E+00
Arthropathy	FA00-FA5Z	Peripheral blood	4.60E-01	6.48E-03	5.10E-02
Asthma	CA23	Nasal and bronchial airway	2.69E-01	-6.54E-02	-1.75E-01
Atopic dermatitis	EA80	Skin	3.36E-02	-1.08E-01	-8.66E-01
Autism	6A02	Whole blood	1.71E-01	-7.16E-02	-2.24E-01
Autoimmune uveitis	9A96	Peripheral monocyte	6.88E-02	-1.38E-01	-7.64E-01
Autosomal dominant monocytopenia	4B04	Whole blood	5.78E-01	9.18E-02	7.51E-01
Bacterial infection of gingival	1C1H	Gingival tissue	7.40E-01	-5.90E-02	-1.60E-01
Batten disease	5C56.1	Whole blood	2.09E-01	6.56E-02	8.27E-01
Behcet's disease	4A62	Peripheral blood	1.39E-01	1.13E-01	7.18E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	4.01E-01	-1.24E-01	-6.95E-01
Bladder cancer	2C94	Bladder tissue	1.08E-03	5.45E-01	2.17E+00
Breast cancer	2C60-2C6Z	Breast tissue	9.45E-03	-7.52E-02	-2.76E-01
Cardioembolic stroke	8B11.20	Whole blood	1.61E-01	6.83E-02	3.80E-01
Cervical cancer	2C77	Cervical tissue	1.22E-01	-8.94E-02	-3.36E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	6.93E-01	2.84E-02	9.87E-02
Chronic hepatitis C	1E51.1	Whole blood	6.17E-01	9.87E-03	7.34E-02
Chronic obstructive pulmonary disease	CA22	Lung tissue	1.52E-01	1.28E-01	4.56E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	1.99E-01	7.82E-02	2.98E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	7.43E-01	-1.62E-02	-1.46E-01
Colon cancer	2B90	Colon tissue	2.85E-06	-1.47E-01	-5.66E-01
Coronary artery disease	BA80-BA8Z	Peripheral blood	6.86E-01	-7.38E-02	-1.96E-01
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	9.23E-01	4.91E-02	2.42E-01
Endometriosis	GA10	Endometrium tissue	4.53E-01	3.92E-02	1.72E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	9.99E-01	-1.04E-03	-4.66E-03
Familial hypercholesterolemia	5C80.00	Whole blood	1.54E-03	-5.09E-01	-1.49E+00
Gastric cancer	2B72	Gastric tissue	1.51E-01	-1.14E-01	-9.10E-01
Glioblastopma	2A00.00	Nervous tissue	2.98E-27	-2.19E-01	-5.22E-01
Glioma	2A00.0Y-2A00.0Z	White matter tissue	4.53E-07	-6.78E-01	-3.33E+00
Head and neck cancer	2D42	Head and neck tissue	1.41E-01	1.23E-02	5.18E-02
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	4.13E-03	-1.77E-01	-8.17E-01
Huntington's disease	8A01.10	Whole blood	7.56E-01	6.80E-03	4.83E-02
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	2.86E-01	1.23E-01	5.65E-01
Immunodeficiency	4A00-4A20	Peripheral blood	2.70E-01	4.26E-02	1.03E+00
Influenza	1.00E+30	Whole blood	1.02E-02	4.76E-01	2.94E+00
Interstitial cystitis	GC00.3	Bladder tissue	3.18E-01	-9.89E-02	-8.51E-01
Intracranial aneurysm	8B01.0	Intracranial artery	7.59E-01	2.83E-02	1.87E-01
Irritable bowel syndrome	DD91.0	Rectal colon tissue	8.24E-01	-1.04E-02	-5.14E-02
Ischemic stroke	8B11	Peripheral blood	3.35E-03	1.70E-01	1.04E+00
Juvenile idiopathic arthritis	FA24	Peripheral blood	2.03E-01	2.96E-02	1.08E-01
Lateral sclerosis	8B60.4	Cervical spinal cord	8.95E-02	-1.21E-01	-4.10E-01
Lateral sclerosis	8B60.4	Skin	5.50E-01	4.15E-02	1.96E-01
Liver cancer	2C12.0	Liver tissue	2.08E-05	-2.18E-01	-1.12E+00
Liver failure	DB99.7-DB99.8	Liver tissue	2.27E-01	8.53E-02	6.86E-01
Lung cancer	2C25	Lung tissue	9.54E-02	-3.21E-02	-1.53E-01
Lupus erythematosus	4A40	Whole blood	1.26E-01	-2.48E-01	-4.09E-01
Major depressive disorder	6A70-6A7Z	Whole blood	1.61E-01	1.64E-02	7.38E-02
Major depressive disorder	6A70-6A7Z	Hippocampus	3.12E-01	-3.68E-02	-2.09E-01
Melanoma	2C30	Skin	9.33E-01	1.73E-01	2.76E-01
Multiple myeloma	2A83.1	Bone marrow	2.37E-04	-4.20E-01	-2.64E+00
Multiple myeloma	2A83.1	Peripheral blood	3.37E-01	9.98E-02	4.61E-01
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	6.02E-01	2.24E-01	6.56E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	1.79E-01	5.03E-02	2.72E-01
Myelofibrosis	2A20.2	Whole blood	8.85E-02	1.53E-01	1.06E+00
Myocardial infarction	BA41-BA50	Peripheral blood	2.15E-01	3.54E-01	6.90E-01
Myopathy	8C70.6	Muscle tissue	1.98E-02	-3.79E-01	-1.51E+00
Neonatal sepsis	KA60	Whole blood	3.82E-03	-1.35E-01	-4.05E-01
Neuroectodermal tumour	2A00.11	Brain stem tissue	9.35E-03	-2.63E-01	-7.97E-01
Non-alcoholic fatty liver disease	DB92	Liver tissue	5.36E-01	5.28E-02	3.78E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	3.95E-01	2.19E-02	3.10E-01
Olive pollen allergy	CA08.00	Peripheral blood	1.64E-03	3.69E-01	3.73E+00
Oral cancer	2B6E	Oral tissue	5.40E-09	-5.72E-01	-1.62E+00
Osteoarthritis	FA00-FA0Z	Synovial tissue	6.64E-01	6.36E-02	1.80E-01
Osteoporosis	FB83.1	Bone marrow	9.04E-02	2.43E-01	3.87E+00
Ovarian cancer	2C73	Ovarian tissue	9.13E-02	-1.51E-01	-6.30E-01
Pancreatic cancer	2C10	Pancreas	1.43E-02	-5.14E-01	-1.03E+00
Parkinson's disease	8A00.0	Substantia nigra tissue	9.15E-01	5.97E-02	1.97E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	3.61E-01	-1.06E-01	-7.68E-01
Pituitary cancer	2D12	Pituitary tissue	3.80E-03	3.33E-01	9.88E-01
Pituitary gonadotrope tumour	2D12	Pituitary tissue	6.89E-02	2.37E-01	8.25E-01
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	2.55E-01	-7.67E-02	-4.41E-01
Polycythemia vera	2A20.4	Whole blood	9.65E-05	1.17E-01	8.58E-01
Pompe disease	5C51.3	Biceps muscle	1.34E-01	-7.41E-02	-7.44E-01
Preterm birth	KA21.4Z	Myometrium	8.77E-01	3.42E-02	1.61E-01
Prostate cancer	2C82	Prostate	4.79E-03	-8.56E-01	-8.26E-01
Psoriasis	EA90	Skin	4.65E-09	-2.73E-01	-5.62E-01
Rectal cancer	2B92	Rectal colon tissue	2.40E-01	-1.69E-01	-5.65E-01
Renal cancer	2C90-2C91	Kidney	3.59E-04	-4.41E+00	-2.18E+00
Retinoblastoma	2D02.2	Uvea	2.31E-07	-5.90E-01	-3.13E+00
Rheumatoid arthritis	FA20	Synovial tissue	1.26E-01	-4.25E-01	-1.12E+00
Rhinovirus infection	CA42.1	Nasal epithelium tissue	9.03E-01	-5.34E-02	-3.80E-01
Schizophrenia	6A20	Prefrontal cortex	9.49E-01	-1.42E-02	-3.77E-02
Schizophrenia	6A20	Superior temporal cortex	1.46E-01	-4.02E-02	-2.76E-01
Scleroderma	4A42.Z	Whole blood	9.00E-01	-1.63E-02	-9.72E-02
Seizure	8A60-8A6Z	Whole blood	4.70E-01	-6.69E-02	-3.12E-01
Sensitive skin	EK0Z	Skin	8.42E-01	-2.24E-02	-2.73E-01
Sepsis with septic shock	1G41	Whole blood	6.80E-02	-5.04E-02	-1.63E-01
Shwachman-Diamond syndrome	3A70.0	Bone marrow	2.39E-02	3.40E-01	1.14E+00
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	8.88E-01	-5.28E-02	-1.61E-01
Simpson golabi behmel syndrome	LD2C	Adipose tissue	3.41E-01	-1.16E-01	-1.21E+00
Sjogren's syndrome	4A43.2	Salivary gland tissue	6.90E-01	1.88E-02	7.27E-02
Skin cancer	2C30-2C3Z	Skin	2.63E-15	-4.13E-01	-6.73E-01
Thrombocythemia	3B63	Whole blood	3.89E-02	6.02E-02	4.19E-01
Thrombocytopenia	3B64	Whole blood	2.76E-01	1.34E-01	6.28E-01
Thyroid cancer	2D10	Thyroid	2.86E-05	1.26E-01	4.49E-01
Tibial muscular dystrophy	8C75	Muscle tissue	4.32E-04	-2.82E-01	-1.59E+00
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	7.73E-01	2.09E-02	8.63E-02
Type 2 diabetes	5A11	Liver tissue	6.49E-01	3.37E-03	6.66E-02
Ureter cancer	2C92	Urothelium	5.21E-01	-8.63E-02	-5.35E-01
Uterine cancer	2C78	Endometrium tissue	6.50E-01	-1.76E-02	-6.14E-02
Vitiligo	ED63.0	Skin	3.60E-01	-8.16E-02	-4.90E-01