Details of the Drug-Related molecule(s) Expression Atlas

General Information of DTP (ID: DTVY9PJ)

• DTP Name: Sodium-dependent vitamin C transporter 2 (SLC23A2) DTP Info
• Gene Name: SVCT2

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	3.64E-05	8.55E-02	3.45E-01
Adrenocortical carcinoma	2D11.Z	Kidney	3.62E-01	-8.02E-03	-8.51E-03
Alopecia	ED70	Skin from scalp	2.99E-01	-5.19E-02	-1.69E-01
Alzheimer's disease	8A20	Entorhinal cortex	1.59E-06	-4.47E-01	-9.05E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	8.13E-01	-3.06E-03	-6.88E-03
Aortic stenosis	BB70	Calcified aortic valve	9.16E-01	-3.45E-03	-1.04E-02
Apnea	7A40	Hyperplastic tonsil	5.89E-01	4.85E-02	2.57E-01
Arthropathy	FA00-FA5Z	Peripheral blood	2.22E-01	-6.97E-03	-4.73E-02
Asthma	CA23	Nasal and bronchial airway	7.94E-01	-8.21E-02	-1.35E-01
Atopic dermatitis	EA80	Skin	9.89E-01	1.15E-02	4.69E-02
Autism	6A02	Whole blood	9.73E-01	-8.87E-02	-3.96E-01
Autoimmune uveitis	9A96	Peripheral monocyte	2.41E-01	3.04E-01	1.41E+00
Autosomal dominant monocytopenia	4B04	Whole blood	1.17E-01	6.84E-01	2.68E+00
Bacterial infection of gingival	1C1H	Gingival tissue	4.80E-01	5.36E-03	2.52E-02
Batten disease	5C56.1	Whole blood	4.48E-01	2.00E-02	2.54E-01
Behcet's disease	4A62	Peripheral blood	4.75E-01	1.00E-01	6.20E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	5.40E-01	-4.08E-02	-1.59E-01
Bladder cancer	2C94	Bladder tissue	1.65E-01	-2.95E-01	-8.08E-01
Breast cancer	2C60-2C6Z	Breast tissue	7.30E-11	-3.21E-01	-6.14E-01
Cardioembolic stroke	8B11.20	Whole blood	2.11E-05	4.37E-01	1.37E+00
Cervical cancer	2C77	Cervical tissue	2.62E-01	5.39E-02	2.74E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	9.84E-01	2.01E-01	4.29E-01
Chronic hepatitis C	1E51.1	Whole blood	7.68E-01	4.58E-02	2.39E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	4.82E-01	8.57E-03	3.88E-02
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	5.54E-02	-5.21E-02	-1.77E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	1.53E-01	-1.75E-01	-7.68E-01
Colon cancer	2B90	Colon tissue	2.17E-03	6.18E-03	2.91E-02
Coronary artery disease	BA80-BA8Z	Peripheral blood	4.20E-01	-8.45E-03	-6.66E-02
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	5.92E-01	-1.24E-01	-2.33E-01
Endometriosis	GA10	Endometrium tissue	1.32E-01	1.30E-01	3.96E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	7.56E-02	-8.63E-02	-9.99E-01
Familial hypercholesterolemia	5C80.00	Whole blood	9.03E-02	-9.32E-02	-5.35E-01
Gastric cancer	2B72	Gastric tissue	9.07E-01	2.18E-01	2.93E-01
Glioblastopma	2A00.00	Nervous tissue	2.23E-85	-1.13E+00	-1.56E+00
Glioma	2A00.0Y-2A00.0Z	White matter tissue	1.29E-01	3.07E-01	5.67E-01
Head and neck cancer	2D42	Head and neck tissue	1.41E-01	1.29E-01	3.09E-01
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	9.47E-02	-9.21E-02	-4.03E-01
Huntington's disease	8A01.10	Whole blood	1.02E-01	-1.13E-02	-1.12E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	6.32E-01	-8.52E-02	-3.61E-01
Immunodeficiency	4A00-4A20	Peripheral blood	4.42E-01	-1.38E-02	-8.82E-02
Influenza	1.00E+30	Whole blood	1.75E-02	-5.21E-01	-3.48E+00
Interstitial cystitis	GC00.3	Bladder tissue	4.70E-01	-2.19E-01	-6.78E-01
Intracranial aneurysm	8B01.0	Intracranial artery	1.97E-03	5.65E-01	2.83E+00
Irritable bowel syndrome	DD91.0	Rectal colon tissue	8.52E-01	3.29E-02	1.50E-01
Ischemic stroke	8B11	Peripheral blood	6.30E-01	-1.66E-02	-9.13E-02
Juvenile idiopathic arthritis	FA24	Peripheral blood	2.16E-01	-9.63E-02	-3.17E-01
Lateral sclerosis	8B60.4	Cervical spinal cord	7.17E-02	7.11E-02	4.52E-01
Lateral sclerosis	8B60.4	Skin	6.56E-01	3.41E-02	2.39E-01
Liver cancer	2C12.0	Liver tissue	6.98E-09	-6.90E-01	-1.20E+00
Liver failure	DB99.7-DB99.8	Liver tissue	3.86E-01	-1.88E-01	-2.18E-01
Lung cancer	2C25	Lung tissue	3.86E-03	3.51E-02	9.06E-02
Lupus erythematosus	4A40	Whole blood	8.65E-01	2.59E-02	7.52E-02
Major depressive disorder	6A70-6A7Z	Whole blood	2.10E-01	6.35E-02	2.52E-01
Major depressive disorder	6A70-6A7Z	Hippocampus	9.57E-01	-7.16E-03	-2.80E-02
Melanoma	2C30	Skin	4.27E-03	6.24E-01	7.80E-01
Multiple myeloma	2A83.1	Bone marrow	1.18E-01	1.87E-01	7.59E-01
Multiple myeloma	2A83.1	Peripheral blood	4.27E-01	-3.65E-02	-2.85E-01
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	3.74E-01	8.80E-02	3.68E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	9.34E-01	-5.96E-02	-2.80E-01
Myelofibrosis	2A20.2	Whole blood	1.51E-01	-5.64E-02	-5.74E-01
Myocardial infarction	BA41-BA50	Peripheral blood	3.60E-02	1.98E-01	4.19E-01
Myopathy	8C70.6	Muscle tissue	2.34E-02	1.20E-01	1.06E+00
Neonatal sepsis	KA60	Whole blood	4.81E-02	4.99E-02	2.69E-01
Neuroectodermal tumour	2A00.11	Brain stem tissue	1.92E-06	-2.05E+00	-3.18E+00
Non-alcoholic fatty liver disease	DB92	Liver tissue	4.00E-01	2.73E-01	6.01E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	7.08E-01	-9.61E-02	-1.13E+00
Olive pollen allergy	CA08.00	Peripheral blood	3.72E-01	5.21E-01	1.05E+00
Oral cancer	2B6E	Oral tissue	2.40E-02	2.13E-01	4.55E-01
Osteoarthritis	FA00-FA0Z	Synovial tissue	1.29E-01	3.79E-01	8.37E-01
Osteoporosis	FB83.1	Bone marrow	1.65E-01	3.83E-01	1.66E+00
Ovarian cancer	2C73	Ovarian tissue	4.56E-02	-3.42E-01	-2.35E-01
Pancreatic cancer	2C10	Pancreas	6.82E-02	-3.71E-01	-1.08E+00
Parkinson's disease	8A00.0	Substantia nigra tissue	9.05E-03	-6.00E-01	-2.08E+00
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	5.02E-01	5.43E-02	3.76E-01
Pituitary cancer	2D12	Pituitary tissue	1.50E-03	1.16E+00	1.70E+00
Pituitary gonadotrope tumour	2D12	Pituitary tissue	6.78E-06	1.34E+00	3.41E+00
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	5.76E-01	-2.61E-02	-1.69E-01
Polycythemia vera	2A20.4	Whole blood	6.93E-02	-3.53E-02	-2.84E-01
Pompe disease	5C51.3	Biceps muscle	1.60E-01	-6.19E-02	-4.54E-01
Preterm birth	KA21.4Z	Myometrium	3.64E-01	1.48E-01	1.47E+00
Prostate cancer	2C82	Prostate	1.02E-01	2.48E-01	3.34E-01
Psoriasis	EA90	Skin	5.07E-48	1.26E+00	3.52E+00
Rectal cancer	2B92	Rectal colon tissue	1.19E-01	1.93E-01	7.50E-01
Renal cancer	2C90-2C91	Kidney	3.05E-01	4.42E-02	6.47E-02
Retinoblastoma	2D02.2	Uvea	5.04E-14	-2.02E+00	-9.61E+00
Rheumatoid arthritis	FA20	Synovial tissue	9.32E-04	6.15E-01	2.31E+00
Rhinovirus infection	CA42.1	Nasal epithelium tissue	5.38E-02	-1.05E-01	-3.65E-01
Schizophrenia	6A20	Prefrontal cortex	2.28E-03	-2.27E-01	-4.51E-01
Schizophrenia	6A20	Superior temporal cortex	8.69E-01	2.74E-02	9.43E-02
Scleroderma	4A42.Z	Whole blood	4.60E-01	1.99E-02	1.06E-01
Seizure	8A60-8A6Z	Whole blood	8.69E-01	3.40E-02	1.36E-01
Sensitive skin	EK0Z	Skin	2.11E-01	1.40E-01	1.16E+00
Sepsis with septic shock	1G41	Whole blood	2.67E-04	6.12E-02	3.21E-01
Shwachman-Diamond syndrome	3A70.0	Bone marrow	3.43E-02	1.26E-01	9.40E-01
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	6.24E-01	-3.56E-02	-3.05E-01
Simpson golabi behmel syndrome	LD2C	Adipose tissue	9.57E-01	6.77E-02	3.56E-01
Sjogren's syndrome	4A43.2	Salivary gland tissue	2.83E-01	-2.04E-01	-1.04E+00
Skin cancer	2C30-2C3Z	Skin	1.85E-58	7.16E-01	2.12E+00
Thrombocythemia	3B63	Whole blood	9.39E-01	-5.36E-02	-5.12E-01
Thrombocytopenia	3B64	Whole blood	2.22E-02	-2.11E-01	-6.24E-01
Thyroid cancer	2D10	Thyroid	1.32E-08	-3.29E-01	-7.90E-01
Tibial muscular dystrophy	8C75	Muscle tissue	3.50E-02	-8.37E-02	-7.23E-01
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	3.12E-01	-3.66E-01	-4.91E-01
Type 2 diabetes	5A11	Liver tissue	1.64E-01	-5.42E-01	-5.75E-01
Ureter cancer	2C92	Urothelium	5.00E-02	1.08E-01	1.08E+00
Uterine cancer	2C78	Endometrium tissue	2.64E-07	1.36E-01	4.76E-01
Vitiligo	ED63.0	Skin	2.59E-01	-9.37E-02	-5.50E-01