Details of the Drug-Related molecule(s) Expression Atlas

General Information of DTP (ID: DTWDEIL)

• DTP Name: Electrogenic sodium bicarbonate cotransporter 1 (SLC4A4) DTP Info
• Gene Name: NBCe1

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	1.16E-11	-1.63E-01	-8.51E-01
Adrenocortical carcinoma	2D11.Z	Kidney	9.80E-01	-1.03E-01	-6.14E-01
Alopecia	ED70	Skin from scalp	2.99E-01	7.03E-02	1.87E-01
Alzheimer's disease	8A20	Entorhinal cortex	7.29E-02	4.90E-02	6.81E-02
Ankylosing spondylitis	FA92.0	Pheripheral blood	2.59E-01	1.37E-01	1.01E+00
Aortic stenosis	BB70	Calcified aortic valve	2.57E-01	-1.13E-01	-2.35E-01
Apnea	7A40	Hyperplastic tonsil	6.01E-01	4.20E-02	2.57E-01
Arthropathy	FA00-FA5Z	Peripheral blood	5.53E-02	-1.02E-01	-4.27E-01
Asthma	CA23	Nasal and bronchial airway	2.46E-01	2.26E-01	2.04E-01
Atopic dermatitis	EA80	Skin	5.33E-01	-4.67E-02	-6.87E-02
Autism	6A02	Whole blood	8.33E-01	-3.36E-02	-1.32E-01
Autoimmune uveitis	9A96	Peripheral monocyte	7.95E-01	1.29E-01	5.57E-01
Autosomal dominant monocytopenia	4B04	Whole blood	8.53E-01	-8.02E-02	-4.06E-01
Bacterial infection of gingival	1C1H	Gingival tissue	9.82E-01	-1.11E-02	-3.91E-02
Batten disease	5C56.1	Whole blood	3.06E-01	1.60E-01	1.42E+00
Behcet's disease	4A62	Peripheral blood	6.75E-01	5.75E-02	1.92E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	7.42E-01	8.45E-03	1.88E-02
Bladder cancer	2C94	Bladder tissue	9.80E-04	-9.76E-01	-2.41E+00
Breast cancer	2C60-2C6Z	Breast tissue	1.20E-50	-8.59E-01	-1.36E+00
Cardioembolic stroke	8B11.20	Whole blood	2.11E-01	1.61E-01	2.69E-01
Cervical cancer	2C77	Cervical tissue	1.50E-01	-5.96E-01	-6.44E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	7.44E-01	-2.58E-02	-1.69E-01
Chronic hepatitis C	1E51.1	Whole blood	9.93E-01	1.49E-01	2.24E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	1.25E-01	2.84E-01	4.97E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	2.95E-01	-1.34E-01	-1.87E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	5.41E-01	1.53E-01	3.31E-01
Colon cancer	2B90	Colon tissue	3.28E-118	-4.03E+00	-4.96E+00
Coronary artery disease	BA80-BA8Z	Peripheral blood	9.88E-01	-1.25E-01	-4.54E-01
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	9.78E-01	8.52E-02	3.67E-01
Endometriosis	GA10	Endometrium tissue	2.29E-01	2.00E-01	3.20E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	2.17E-01	-1.18E-01	-8.05E-01
Familial hypercholesterolemia	5C80.00	Whole blood	4.68E-06	-3.27E-01	-9.91E-01
Gastric cancer	2B72	Gastric tissue	2.37E-01	-4.54E-01	-1.25E+00
Glioblastopma	2A00.00	Nervous tissue	4.36E-01	6.42E-02	7.02E-02
Glioma	2A00.0Y-2A00.0Z	White matter tissue	7.32E-02	5.18E-01	5.94E-01
Head and neck cancer	2D42	Head and neck tissue	1.66E-25	-1.54E+00	-1.50E+00
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	5.74E-01	-7.38E-02	-1.15E-01
Huntington's disease	8A01.10	Whole blood	5.29E-01	-5.24E-02	-5.76E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	1.14E-02	6.40E-01	1.96E+00
Immunodeficiency	4A00-4A20	Peripheral blood	6.70E-03	-1.48E-01	-1.67E+00
Influenza	1.00E+30	Whole blood	8.45E-03	4.42E-01	3.19E+00
Interstitial cystitis	GC00.3	Bladder tissue	2.86E-02	-4.22E-01	-1.24E+00
Intracranial aneurysm	8B01.0	Intracranial artery	8.55E-01	7.95E-02	2.32E-01
Irritable bowel syndrome	DD91.0	Rectal colon tissue	3.60E-01	-1.20E-02	-4.35E-02
Ischemic stroke	8B11	Peripheral blood	6.89E-01	9.11E-02	2.68E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	4.51E-01	-6.98E-02	-1.05E-01
Lateral sclerosis	8B60.4	Cervical spinal cord	4.74E-01	2.63E-01	5.14E-01
Lateral sclerosis	8B60.4	Skin	6.79E-01	-6.58E-02	-2.17E-01
Liver cancer	2C12.0	Liver tissue	1.03E-08	-7.22E-01	-9.37E-01
Liver failure	DB99.7-DB99.8	Liver tissue	1.85E-02	4.05E-01	1.01E+00
Lung cancer	2C25	Lung tissue	7.17E-43	-8.43E-01	-1.79E+00
Lupus erythematosus	4A40	Whole blood	4.26E-02	-1.63E-01	-3.20E-01
Major depressive disorder	6A70-6A7Z	Whole blood	6.34E-01	-4.42E-02	-9.63E-02
Major depressive disorder	6A70-6A7Z	Hippocampus	4.25E-02	-3.30E-01	-7.17E-01
Melanoma	2C30	Skin	4.74E-02	2.15E-01	3.07E-01
Multiple myeloma	2A83.1	Bone marrow	8.82E-01	-5.22E-02	-2.32E-01
Multiple myeloma	2A83.1	Peripheral blood	5.28E-01	1.39E-01	4.53E-01
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	1.81E-01	-7.95E-02	-2.83E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	7.09E-01	-2.57E-03	-1.60E-02
Myelofibrosis	2A20.2	Whole blood	1.41E-01	1.80E-01	6.80E-01
Myocardial infarction	BA41-BA50	Peripheral blood	3.27E-01	-1.79E-01	-2.17E-01
Myopathy	8C70.6	Muscle tissue	6.67E-01	-7.98E-03	-2.04E-02
Neonatal sepsis	KA60	Whole blood	3.14E-10	-2.35E-01	-7.40E-01
Neuroectodermal tumour	2A00.11	Brain stem tissue	2.92E-11	-2.41E+00	-6.76E+00
Non-alcoholic fatty liver disease	DB92	Liver tissue	2.15E-01	1.95E-01	3.05E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	3.57E-01	6.16E-02	4.39E-01
Olive pollen allergy	CA08.00	Peripheral blood	7.15E-03	3.88E-01	2.36E+00
Oral cancer	2B6E	Oral tissue	2.67E-04	-3.62E-01	-8.75E-01
Osteoarthritis	FA00-FA0Z	Synovial tissue	4.86E-03	-5.63E-01	-1.52E+00
Osteoporosis	FB83.1	Bone marrow	6.88E-01	5.94E-02	2.22E-01
Ovarian cancer	2C73	Ovarian tissue	3.17E-01	-1.76E-01	-2.01E-01
Pancreatic cancer	2C10	Pancreas	2.22E-03	-2.00E+00	-1.29E+00
Parkinson's disease	8A00.0	Substantia nigra tissue	5.40E-01	6.83E-01	9.70E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	1.10E-02	-2.50E-01	-1.85E+00
Pituitary cancer	2D12	Pituitary tissue	2.80E-06	-1.25E+00	-2.35E+00
Pituitary gonadotrope tumour	2D12	Pituitary tissue	2.46E-05	-1.32E+00	-2.39E+00
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	4.82E-01	1.10E-01	3.58E-01
Polycythemia vera	2A20.4	Whole blood	6.72E-01	2.12E-02	8.92E-02
Pompe disease	5C51.3	Biceps muscle	3.48E-01	-4.12E-01	-5.34E-01
Preterm birth	KA21.4Z	Myometrium	6.67E-02	1.68E-01	1.48E+00
Prostate cancer	2C82	Prostate	2.31E-02	8.27E-01	6.49E-01
Psoriasis	EA90	Skin	4.60E-12	-2.72E-01	-7.79E-01
Rectal cancer	2B92	Rectal colon tissue	5.01E-07	-2.60E+00	-6.11E+00
Renal cancer	2C90-2C91	Kidney	8.30E-04	-1.22E+00	-1.30E+00
Retinoblastoma	2D02.2	Uvea	1.03E-05	-7.02E-01	-1.72E+00
Rheumatoid arthritis	FA20	Synovial tissue	1.34E-03	-1.77E+00	-2.79E+00
Rhinovirus infection	CA42.1	Nasal epithelium tissue	9.86E-01	-4.25E-02	-1.35E-01
Schizophrenia	6A20	Prefrontal cortex	2.72E-01	-5.00E-02	-5.72E-02
Schizophrenia	6A20	Superior temporal cortex	2.40E-01	2.74E-02	8.72E-02
Scleroderma	4A42.Z	Whole blood	1.99E-05	-2.70E-01	-2.75E+00
Seizure	8A60-8A6Z	Whole blood	4.82E-01	1.66E-02	9.88E-02
Sensitive skin	EK0Z	Skin	3.65E-01	-6.10E-02	-2.88E-01
Sepsis with septic shock	1G41	Whole blood	3.41E-27	-3.46E-01	-9.47E-01
Shwachman-Diamond syndrome	3A70.0	Bone marrow	3.64E-01	3.14E-01	1.04E+00
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	5.46E-01	-2.99E-02	-2.03E-01
Simpson golabi behmel syndrome	LD2C	Adipose tissue	4.90E-02	7.95E-01	1.87E+00
Sjogren's syndrome	4A43.2	Salivary gland tissue	8.73E-01	5.03E-02	3.41E-01
Skin cancer	2C30-2C3Z	Skin	7.44E-14	2.44E-01	6.29E-01
Thrombocythemia	3B63	Whole blood	7.26E-01	4.97E-02	2.28E-01
Thrombocytopenia	3B64	Whole blood	7.50E-02	-6.48E-01	-7.33E-01
Thyroid cancer	2D10	Thyroid	5.18E-44	-2.65E+00	-2.60E+00
Tibial muscular dystrophy	8C75	Muscle tissue	3.51E-01	6.95E-02	3.65E-01
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	8.54E-01	1.92E-01	3.39E-01
Type 2 diabetes	5A11	Liver tissue	2.06E-01	-3.47E-01	-8.10E-01
Ureter cancer	2C92	Urothelium	5.53E-01	-5.05E-02	-1.62E-01
Uterine cancer	2C78	Endometrium tissue	1.57E-02	-2.55E-01	-3.87E-01
Vitiligo	ED63.0	Skin	8.05E-01	-5.82E-02	-6.38E-02