Details of the Drug-Related molecule(s) Expression Atlas

General Information of DTP (ID: DTWY9RT)

• DTP Name: Cationic amino acid transporter 2 (SLC7A2) DTP Info
• Gene Name: CAT2

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	2.61E-03	2.76E-02	1.53E-01
Adrenocortical carcinoma	2D11.Z	Kidney	1.07E-02	-1.01E-01	-5.26E-01
Alopecia	ED70	Skin from scalp	6.34E-02	-9.39E-02	-3.62E-01
Alzheimer's disease	8A20	Entorhinal cortex	2.82E-03	3.68E-01	7.03E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	8.66E-01	-2.68E-02	-1.86E-01
Aortic stenosis	BB70	Calcified aortic valve	9.76E-01	-4.32E-01	-5.67E-01
Apnea	7A40	Hyperplastic tonsil	4.33E-01	-1.61E-01	-1.15E+00
Arthropathy	FA00-FA5Z	Peripheral blood	1.22E-01	4.03E-02	2.44E-01
Asthma	CA23	Nasal and bronchial airway	4.20E-06	-1.69E-01	-9.61E-02
Atopic dermatitis	EA80	Skin	6.76E-01	2.44E-02	2.14E-01
Autism	6A02	Whole blood	6.75E-02	-8.17E-02	-3.41E-01
Autoimmune uveitis	9A96	Peripheral monocyte	5.68E-01	-8.01E-02	-4.59E-01
Autosomal dominant monocytopenia	4B04	Whole blood	8.18E-02	8.34E-02	7.60E-01
Bacterial infection of gingival	1C1H	Gingival tissue	3.61E-03	5.70E-02	2.82E-01
Batten disease	5C56.1	Whole blood	7.45E-01	1.28E-02	1.73E-01
Behcet's disease	4A62	Peripheral blood	1.50E-01	5.02E-02	3.10E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	5.63E-01	-2.89E-03	-1.81E-02
Bladder cancer	2C94	Bladder tissue	1.07E-02	6.18E-01	1.52E+00
Breast cancer	2C60-2C6Z	Breast tissue	2.11E-03	-4.57E-03	-1.52E-02
Cardioembolic stroke	8B11.20	Whole blood	2.22E-01	7.35E-02	3.92E-01
Cervical cancer	2C77	Cervical tissue	2.84E-01	-9.49E-02	-4.12E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	6.29E-01	-2.30E-02	-9.55E-02
Chronic hepatitis C	1E51.1	Whole blood	8.19E-01	-1.72E-02	-8.45E-02
Chronic obstructive pulmonary disease	CA22	Lung tissue	1.66E-01	3.82E-02	1.76E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	1.29E-05	-7.63E-01	-9.53E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	3.54E-01	5.10E-02	4.25E-01
Colon cancer	2B90	Colon tissue	1.81E-04	-8.86E-02	-3.71E-01
Coronary artery disease	BA80-BA8Z	Peripheral blood	1.01E-01	-1.72E-01	-8.92E-01
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	3.95E-01	1.33E-01	5.04E-01
Endometriosis	GA10	Endometrium tissue	1.59E-04	3.35E-01	1.49E+00
Familial hypercholesterolemia	5C80.00	Peripheral blood	7.65E-01	-3.27E-03	-1.59E-02
Familial hypercholesterolemia	5C80.00	Whole blood	4.73E-05	-3.16E-01	-1.13E+00
Gastric cancer	2B72	Gastric tissue	1.64E-01	1.22E-01	1.05E+00
Glioblastopma	2A00.00	Nervous tissue	9.56E-18	-1.41E-01	-2.88E-01
Glioma	2A00.0Y-2A00.0Z	White matter tissue	1.03E-07	-9.23E-01	-3.73E+00
Head and neck cancer	2D42	Head and neck tissue	3.03E-09	-2.38E-01	-2.94E-01
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	4.73E-01	-6.78E-02	-3.65E-01
Huntington's disease	8A01.10	Whole blood	9.43E-01	-2.88E-02	-2.37E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	1.03E-02	-4.74E-01	-2.04E+00
Immunodeficiency	4A00-4A20	Peripheral blood	4.16E-01	3.43E-02	7.01E-01
Influenza	1.00E+30	Whole blood	5.22E-02	4.72E-01	2.21E+00
Interstitial cystitis	GC00.3	Bladder tissue	7.74E-01	7.95E-02	4.49E-01
Intracranial aneurysm	8B01.0	Intracranial artery	7.37E-01	6.72E-03	4.21E-02
Irritable bowel syndrome	DD91.0	Rectal colon tissue	4.99E-01	6.63E-02	1.86E-01
Ischemic stroke	8B11	Peripheral blood	8.78E-02	1.28E-02	6.68E-02
Juvenile idiopathic arthritis	FA24	Peripheral blood	3.50E-03	7.72E-02	3.45E-01
Lateral sclerosis	8B60.4	Cervical spinal cord	7.17E-01	-2.46E-04	-1.30E-03
Lateral sclerosis	8B60.4	Skin	8.18E-01	-5.26E-02	-6.04E-01
Liver cancer	2C12.0	Liver tissue	2.25E-05	-6.24E-01	-5.01E-01
Liver failure	DB99.7-DB99.8	Liver tissue	7.74E-02	-2.11E-01	-6.34E-01
Lung cancer	2C25	Lung tissue	8.47E-01	-5.21E-02	-1.60E-01
Lupus erythematosus	4A40	Whole blood	5.23E-02	-1.86E-01	-3.56E-01
Major depressive disorder	6A70-6A7Z	Whole blood	7.50E-01	-1.55E-02	-4.53E-02
Major depressive disorder	6A70-6A7Z	Hippocampus	6.63E-01	2.34E-03	1.38E-02
Melanoma	2C30	Skin	2.80E-01	-1.31E-01	-2.24E-01
Multiple myeloma	2A83.1	Bone marrow	6.02E-04	-3.84E-01	-1.98E+00
Multiple myeloma	2A83.1	Peripheral blood	1.38E-01	3.71E-02	3.35E-01
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	5.26E-01	-9.51E-03	-4.87E-02
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	3.90E-02	-1.43E-01	-7.25E-01
Myelofibrosis	2A20.2	Whole blood	2.58E-05	1.91E-01	1.16E+00
Myocardial infarction	BA41-BA50	Peripheral blood	8.63E-01	8.26E-02	1.25E-01
Myopathy	8C70.6	Muscle tissue	7.88E-01	-5.37E-01	-3.10E-01
Neonatal sepsis	KA60	Whole blood	5.27E-01	4.28E-03	1.94E-02
Neuroectodermal tumour	2A00.11	Brain stem tissue	7.08E-03	-3.40E-01	-1.02E+00
Non-alcoholic fatty liver disease	DB92	Liver tissue	6.75E-01	-1.94E-01	-2.41E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	6.74E-02	7.52E-02	1.25E+00
Olive pollen allergy	CA08.00	Peripheral blood	3.69E-01	2.18E-01	1.08E+00
Oral cancer	2B6E	Oral tissue	5.96E-05	-2.25E-01	-8.55E-01
Osteoarthritis	FA00-FA0Z	Synovial tissue	5.36E-01	-4.64E-02	-2.65E-01
Osteoporosis	FB83.1	Bone marrow	2.76E-02	2.64E-01	3.60E+00
Ovarian cancer	2C73	Ovarian tissue	4.38E-01	-1.44E-01	-2.56E-01
Pancreatic cancer	2C10	Pancreas	5.85E-02	-1.99E-01	-1.63E-01
Parkinson's disease	8A00.0	Substantia nigra tissue	3.11E-01	-5.29E-02	-2.64E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	2.41E-01	-5.28E-02	-3.49E-01
Pituitary cancer	2D12	Pituitary tissue	4.71E-01	7.50E-02	2.37E-01
Pituitary gonadotrope tumour	2D12	Pituitary tissue	7.35E-01	6.50E-02	2.73E-01
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	2.23E-01	1.16E-01	5.28E-01
Polycythemia vera	2A20.4	Whole blood	3.77E-09	1.63E-01	1.14E+00
Pompe disease	5C51.3	Biceps muscle	8.77E-04	-4.11E-01	-2.21E+00
Preterm birth	KA21.4Z	Myometrium	9.60E-01	-6.46E-02	-5.86E-01
Prostate cancer	2C82	Prostate	2.68E-03	1.99E-01	4.71E-01
Psoriasis	EA90	Skin	2.85E-01	9.67E-02	2.98E-01
Rectal cancer	2B92	Rectal colon tissue	7.84E-02	-1.43E-01	-1.09E+00
Renal cancer	2C90-2C91	Kidney	8.94E-01	3.17E-02	8.62E-02
Retinoblastoma	2D02.2	Uvea	5.34E-02	-1.37E-01	-1.40E+00
Rheumatoid arthritis	FA20	Synovial tissue	6.66E-01	2.97E-02	1.47E-01
Rhinovirus infection	CA42.1	Nasal epithelium tissue	6.59E-02	-2.79E-01	-4.60E-01
Schizophrenia	6A20	Prefrontal cortex	4.19E-01	4.47E-02	1.90E-01
Schizophrenia	6A20	Superior temporal cortex	2.94E-01	-5.51E-02	-4.73E-01
Scleroderma	4A42.Z	Whole blood	1.49E-04	5.65E-01	2.51E+00
Seizure	8A60-8A6Z	Whole blood	7.56E-01	5.38E-02	2.45E-01
Sensitive skin	EK0Z	Skin	7.54E-01	1.43E-02	2.06E-01
Sepsis with septic shock	1G41	Whole blood	7.93E-05	6.78E-02	3.24E-01
Shwachman-Diamond syndrome	3A70.0	Bone marrow	2.80E-01	2.40E-01	1.24E+00
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	1.38E-01	3.52E-02	1.34E-01
Simpson golabi behmel syndrome	LD2C	Adipose tissue	9.13E-01	4.89E-02	1.68E-01
Sjogren's syndrome	4A43.2	Salivary gland tissue	2.08E-01	-1.74E-01	-8.00E-01
Skin cancer	2C30-2C3Z	Skin	2.00E-02	3.99E-02	1.18E-01
Thrombocythemia	3B63	Whole blood	1.60E-03	2.02E-01	1.45E+00
Thrombocytopenia	3B64	Whole blood	3.09E-01	6.37E-01	1.62E+00
Thyroid cancer	2D10	Thyroid	1.84E-01	5.67E-02	1.13E-01
Tibial muscular dystrophy	8C75	Muscle tissue	6.53E-05	-8.58E-01	-1.49E+00
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	7.83E-01	9.32E-03	7.02E-02
Type 2 diabetes	5A11	Liver tissue	9.87E-01	5.10E-02	2.08E-01
Ureter cancer	2C92	Urothelium	2.43E-01	5.44E-02	4.33E-01
Uterine cancer	2C78	Endometrium tissue	2.55E-02	-3.45E-02	-1.02E-01
Vitiligo	ED63.0	Skin	2.75E-02	-8.32E-02	-1.20E+00