Details of the Drug-Related molecule(s) Expression Atlas

General Information of DTP (ID: DTX8KP0)

• DTP Name: Sodium- and chloride-dependent GABA transporter 2 (SLC6A13) DTP Info
• Gene Name: GAT2

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	7.42E-02	3.40E-02	1.89E-01
Adrenocortical carcinoma	2D11.Z	Kidney	2.68E-02	9.06E-02	4.47E-01
Alopecia	ED70	Skin from scalp	3.44E-01	9.87E-03	3.30E-02
Alzheimer's disease	8A20	Entorhinal cortex	2.37E-01	1.88E-02	4.96E-02
Ankylosing spondylitis	FA92.0	Pheripheral blood	3.82E-01	-1.05E-02	-7.58E-02
Aortic stenosis	BB70	Calcified aortic valve	7.19E-01	1.40E-01	1.70E-01
Apnea	7A40	Hyperplastic tonsil	3.35E-01	-3.52E-01	-1.31E+00
Arthropathy	FA00-FA5Z	Peripheral blood	8.84E-01	-4.56E-03	-3.22E-02
Asthma	CA23	Nasal and bronchial airway	8.74E-07	-5.76E-01	-7.31E-01
Atopic dermatitis	EA80	Skin	5.30E-01	9.98E-02	4.73E-01
Autism	6A02	Whole blood	5.40E-02	-5.40E-02	-2.07E-01
Autoimmune uveitis	9A96	Peripheral monocyte	4.12E-01	-1.74E-02	-1.77E-01
Autosomal dominant monocytopenia	4B04	Whole blood	7.35E-02	-1.34E-01	-2.20E+00
Bacterial infection of gingival	1C1H	Gingival tissue	4.91E-08	2.09E-01	7.30E-01
Batten disease	5C56.1	Whole blood	7.51E-02	2.16E-01	6.74E-01
Behcet's disease	4A62	Peripheral blood	2.85E-01	1.22E-01	7.86E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	5.35E-02	4.67E-02	2.92E-01
Bladder cancer	2C94	Bladder tissue	3.50E-05	4.17E-01	2.97E+00
Breast cancer	2C60-2C6Z	Breast tissue	5.08E-12	-1.39E-01	-4.74E-01
Cardioembolic stroke	8B11.20	Whole blood	1.38E-03	3.21E-01	8.70E-01
Cervical cancer	2C77	Cervical tissue	8.60E-01	1.91E-02	5.92E-02
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	7.87E-01	-6.68E-02	-3.10E-01
Chronic hepatitis C	1E51.1	Whole blood	9.20E-02	-9.82E-02	-5.51E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	9.80E-02	7.79E-02	3.84E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	1.61E-02	-2.90E-01	-5.24E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	8.13E-02	-9.82E-02	-1.15E-01
Colon cancer	2B90	Colon tissue	2.71E-08	-9.72E-02	-5.10E-01
Coronary artery disease	BA80-BA8Z	Peripheral blood	1.38E-01	-4.58E-01	-8.15E-01
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	1.09E-01	-5.65E-01	-8.41E-01
Endometriosis	GA10	Endometrium tissue	2.86E-01	2.73E-01	8.52E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	6.97E-01	5.17E-03	5.09E-02
Familial hypercholesterolemia	5C80.00	Whole blood	9.98E-06	-3.29E-01	-1.09E+00
Gastric cancer	2B72	Gastric tissue	7.04E-02	-1.95E-01	-1.79E+00
Glioblastopma	2A00.00	Nervous tissue	1.04E-48	-8.11E-01	-1.49E+00
Glioma	2A00.0Y-2A00.0Z	White matter tissue	1.42E-01	2.16E-01	7.00E-01
Head and neck cancer	2D42	Head and neck tissue	4.64E-08	-1.79E-01	-2.16E-01
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	3.14E-01	-1.48E-02	-5.29E-02
Huntington's disease	8A01.10	Whole blood	6.63E-01	1.29E-02	1.24E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	4.00E-01	7.53E-02	7.05E-01
Immunodeficiency	4A00-4A20	Peripheral blood	2.14E-01	1.29E-01	1.03E+00
Influenza	1.00E+30	Whole blood	1.59E-03	3.96E-01	5.33E+00
Interstitial cystitis	GC00.3	Bladder tissue	5.78E-02	1.95E-01	1.75E+00
Intracranial aneurysm	8B01.0	Intracranial artery	4.09E-03	1.46E+00	3.50E+00
Irritable bowel syndrome	DD91.0	Rectal colon tissue	5.80E-03	5.02E-02	2.28E-01
Ischemic stroke	8B11	Peripheral blood	5.53E-02	4.42E-02	4.51E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	7.76E-01	4.82E-03	2.06E-02
Lateral sclerosis	8B60.4	Cervical spinal cord	4.27E-02	-3.91E-01	-7.21E-01
Lateral sclerosis	8B60.4	Skin	1.75E-01	6.96E-02	5.21E-01
Liver cancer	2C12.0	Liver tissue	6.41E-06	-5.79E-01	-1.47E+00
Liver failure	DB99.7-DB99.8	Liver tissue	1.02E-03	-4.68E-01	-1.89E+00
Lung cancer	2C25	Lung tissue	6.97E-47	-5.74E-01	-1.57E+00
Lupus erythematosus	4A40	Whole blood	1.74E-02	-1.08E-01	-1.85E-01
Major depressive disorder	6A70-6A7Z	Whole blood	1.70E-01	1.48E-01	5.11E-01
Major depressive disorder	6A70-6A7Z	Hippocampus	2.97E-01	9.18E-02	5.76E-01
Melanoma	2C30	Skin	5.45E-01	3.60E-01	5.26E-01
Multiple myeloma	2A83.1	Bone marrow	9.97E-04	-6.07E-01	-1.76E+00
Multiple myeloma	2A83.1	Peripheral blood	2.80E-01	3.30E-02	2.43E-01
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	7.64E-01	2.21E-01	5.34E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	4.65E-01	3.97E-02	1.60E-01
Myelofibrosis	2A20.2	Whole blood	5.08E-03	1.05E-01	6.17E-01
Myocardial infarction	BA41-BA50	Peripheral blood	3.96E-01	2.78E-02	3.76E-02
Myopathy	8C70.6	Muscle tissue	1.24E-01	-9.66E-02	-1.00E+00
Neonatal sepsis	KA60	Whole blood	7.11E-01	-2.63E-02	-1.22E-01
Neuroectodermal tumour	2A00.11	Brain stem tissue	4.14E-06	-1.88E+00	-3.04E+00
Non-alcoholic fatty liver disease	DB92	Liver tissue	5.47E-01	-4.10E-02	-1.41E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	5.15E-01	-6.20E-02	-2.28E-01
Olive pollen allergy	CA08.00	Peripheral blood	6.55E-01	4.99E-02	4.87E-02
Oral cancer	2B6E	Oral tissue	8.36E-02	-3.01E-01	-1.02E+00
Osteoarthritis	FA00-FA0Z	Synovial tissue	9.81E-01	1.08E-02	8.89E-02
Osteoporosis	FB83.1	Bone marrow	7.98E-01	9.16E-02	4.77E-01
Ovarian cancer	2C73	Ovarian tissue	2.05E-03	5.74E-01	1.12E+00
Pancreatic cancer	2C10	Pancreas	4.19E-02	-2.19E-01	-5.34E-01
Parkinson's disease	8A00.0	Substantia nigra tissue	8.13E-01	-1.24E-01	-3.06E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	1.70E-02	1.15E-01	1.03E+00
Pituitary cancer	2D12	Pituitary tissue	8.58E-01	1.83E-01	2.94E-01
Pituitary gonadotrope tumour	2D12	Pituitary tissue	7.81E-01	9.55E-02	1.34E-01
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	7.75E-01	2.30E-03	2.67E-02
Polycythemia vera	2A20.4	Whole blood	6.08E-03	9.29E-02	5.31E-01
Pompe disease	5C51.3	Biceps muscle	5.58E-01	-5.89E-02	-4.75E-01
Preterm birth	KA21.4Z	Myometrium	7.28E-01	-6.75E-02	-4.78E-01
Prostate cancer	2C82	Prostate	9.86E-03	-3.52E-01	-4.53E-01
Psoriasis	EA90	Skin	1.11E-11	-1.75E-01	-6.01E-01
Rectal cancer	2B92	Rectal colon tissue	2.38E-02	-2.78E-01	-1.37E+00
Renal cancer	2C90-2C91	Kidney	1.06E-03	-1.27E+00	-1.43E+00
Retinoblastoma	2D02.2	Uvea	3.70E-03	-5.01E-01	-1.19E+00
Rheumatoid arthritis	FA20	Synovial tissue	6.53E-03	-3.21E-01	-1.97E+00
Rhinovirus infection	CA42.1	Nasal epithelium tissue	4.35E-01	-3.73E-02	-1.29E-01
Schizophrenia	6A20	Prefrontal cortex	1.51E-01	-9.72E-02	-1.14E-01
Schizophrenia	6A20	Superior temporal cortex	9.47E-01	-3.05E-03	-2.54E-02
Scleroderma	4A42.Z	Whole blood	3.14E-01	-8.19E-02	-5.24E-01
Seizure	8A60-8A6Z	Whole blood	3.63E-01	-6.38E-02	-3.39E-01
Sensitive skin	EK0Z	Skin	5.11E-01	1.63E-02	1.45E-01
Sepsis with septic shock	1G41	Whole blood	2.36E-02	4.63E-02	2.09E-01
Shwachman-Diamond syndrome	3A70.0	Bone marrow	6.14E-02	3.86E-01	1.12E+00
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	4.06E-02	1.20E-01	6.78E-01
Simpson golabi behmel syndrome	LD2C	Adipose tissue	2.12E-01	5.30E-02	8.93E-01
Sjogren's syndrome	4A43.2	Salivary gland tissue	9.59E-01	6.99E-02	3.24E-01
Skin cancer	2C30-2C3Z	Skin	1.14E-01	-1.50E-01	-3.79E-01
Thrombocythemia	3B63	Whole blood	7.67E-03	2.08E-01	1.26E+00
Thrombocytopenia	3B64	Whole blood	7.85E-01	4.93E-02	3.79E-01
Thyroid cancer	2D10	Thyroid	4.90E-28	-7.84E-01	-1.84E+00
Tibial muscular dystrophy	8C75	Muscle tissue	4.73E-01	-9.17E-03	-5.33E-02
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	1.46E-01	-2.53E-01	-3.68E+00
Type 2 diabetes	5A11	Liver tissue	1.60E-02	-2.08E-01	-1.61E+00
Ureter cancer	2C92	Urothelium	3.06E-01	-1.18E-01	-3.61E-01
Uterine cancer	2C78	Endometrium tissue	2.24E-10	2.24E-01	6.27E-01
Vitiligo	ED63.0	Skin	1.52E-01	-1.49E-01	-5.18E-01