Details of the Drug-Related molecule(s) Expression Atlas

General Information of DTP (ID: DTXBIQG)

• DTP Name: Sodium- and chloride-dependent GABA transporter 3 (SLC6A11) DTP Info
• Gene Name: GAT3

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	2.02E-04	1.16E-01	6.26E-01
Adrenocortical carcinoma	2D11.Z	Kidney	7.54E-01	2.80E-02	1.19E-01
Alopecia	ED70	Skin from scalp	3.69E-02	-1.17E-01	-2.82E-01
Alzheimer's disease	8A20	Entorhinal cortex	8.24E-01	1.81E-02	4.48E-02
Ankylosing spondylitis	FA92.0	Pheripheral blood	3.37E-01	5.12E-02	3.61E-01
Aortic stenosis	BB70	Calcified aortic valve	7.73E-01	-2.78E-02	-1.44E-01
Apnea	7A40	Hyperplastic tonsil	6.39E-01	-3.82E-02	-1.55E-01
Arthropathy	FA00-FA5Z	Peripheral blood	6.42E-02	8.85E-02	9.78E-01
Asthma	CA23	Nasal and bronchial airway	5.14E-01	3.46E-02	1.03E-01
Atopic dermatitis	EA80	Skin	1.46E-03	2.09E-01	8.93E-01
Autism	6A02	Whole blood	8.76E-02	-1.94E-02	-1.03E-01
Autoimmune uveitis	9A96	Peripheral monocyte	5.20E-02	-2.26E-01	-2.40E+00
Autosomal dominant monocytopenia	4B04	Whole blood	1.13E-01	-1.77E-02	-1.32E-01
Bacterial infection of gingival	1C1H	Gingival tissue	2.31E-02	-4.82E-02	-1.52E-01
Batten disease	5C56.1	Whole blood	9.38E-01	2.99E-03	3.64E-02
Behcet's disease	4A62	Peripheral blood	8.03E-01	-5.61E-02	-2.53E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	4.60E-01	1.65E-02	1.18E-01
Bladder cancer	2C94	Bladder tissue	4.49E-02	1.31E-01	7.80E-01
Breast cancer	2C60-2C6Z	Breast tissue	6.07E-01	-3.05E-02	-1.34E-01
Cardioembolic stroke	8B11.20	Whole blood	5.55E-01	-6.33E-02	-2.66E-01
Cervical cancer	2C77	Cervical tissue	2.33E-01	-7.86E-02	-3.95E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	8.84E-01	-4.30E-02	-1.78E-01
Chronic hepatitis C	1E51.1	Whole blood	1.58E-01	1.46E-01	1.12E+00
Chronic obstructive pulmonary disease	CA22	Lung tissue	4.23E-01	-2.10E-02	-9.06E-02
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	6.90E-06	2.08E-01	9.61E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	8.33E-01	1.26E-02	9.06E-02
Colon cancer	2B90	Colon tissue	1.89E-04	-8.72E-02	-3.45E-01
Coronary artery disease	BA80-BA8Z	Peripheral blood	1.64E-01	-1.25E-01	-6.30E-01
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	8.30E-01	-3.25E-02	-2.67E-01
Endometriosis	GA10	Endometrium tissue	4.15E-01	-6.79E-02	-2.28E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	6.68E-01	6.68E-05	5.71E-04
Familial hypercholesterolemia	5C80.00	Whole blood	4.90E-01	3.63E-02	1.65E-01
Gastric cancer	2B72	Gastric tissue	2.58E-02	-3.09E-01	-3.24E+00
Glioblastopma	2A00.00	Nervous tissue	1.92E-34	-4.60E-01	-8.96E-01
Glioma	2A00.0Y-2A00.0Z	White matter tissue	2.34E-03	-7.66E-01	-1.12E+00
Head and neck cancer	2D42	Head and neck tissue	7.80E-06	3.08E-01	7.56E-01
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	8.62E-01	-6.23E-02	-2.29E-01
Huntington's disease	8A01.10	Whole blood	6.68E-01	8.57E-02	4.09E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	3.00E-01	-4.09E-02	-4.24E-01
Immunodeficiency	4A00-4A20	Peripheral blood	1.29E-01	8.57E-02	6.56E-01
Influenza	1.00E+30	Whole blood	6.05E-02	2.51E-01	2.34E+00
Interstitial cystitis	GC00.3	Bladder tissue	8.32E-01	-3.43E-02	-6.21E-01
Intracranial aneurysm	8B01.0	Intracranial artery	2.54E-01	-8.52E-02	-4.29E-01
Irritable bowel syndrome	DD91.0	Rectal colon tissue	2.11E-01	9.66E-02	3.07E-01
Ischemic stroke	8B11	Peripheral blood	9.18E-01	1.47E-02	9.38E-02
Juvenile idiopathic arthritis	FA24	Peripheral blood	1.64E-01	1.49E-01	3.06E-01
Lateral sclerosis	8B60.4	Cervical spinal cord	5.70E-01	-1.02E-01	-4.40E-01
Lateral sclerosis	8B60.4	Skin	1.09E-01	-1.47E-01	-1.98E+00
Liver cancer	2C12.0	Liver tissue	3.84E-03	2.26E-02	8.20E-02
Liver failure	DB99.7-DB99.8	Liver tissue	4.79E-01	1.17E-01	7.06E-01
Lung cancer	2C25	Lung tissue	4.70E-02	4.71E-02	2.01E-01
Lupus erythematosus	4A40	Whole blood	8.99E-01	2.01E-02	5.26E-02
Major depressive disorder	6A70-6A7Z	Whole blood	8.93E-03	4.41E-02	2.91E-01
Major depressive disorder	6A70-6A7Z	Hippocampus	1.29E-01	-2.69E-02	-1.84E-01
Melanoma	2C30	Skin	6.83E-03	-2.57E-01	-8.38E-01
Multiple myeloma	2A83.1	Bone marrow	2.93E-01	7.17E-02	3.71E-01
Multiple myeloma	2A83.1	Peripheral blood	6.60E-01	6.01E-02	3.75E-01
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	1.52E-01	3.01E-01	1.37E+00
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	1.06E-01	-1.22E-03	-7.15E-03
Myelofibrosis	2A20.2	Whole blood	7.49E-01	2.10E-03	1.60E-02
Myocardial infarction	BA41-BA50	Peripheral blood	9.91E-01	-3.27E-03	-5.30E-03
Myopathy	8C70.6	Muscle tissue	2.41E-01	-6.36E-02	-4.78E-01
Neonatal sepsis	KA60	Whole blood	1.11E-02	7.70E-02	3.34E-01
Neuroectodermal tumour	2A00.11	Brain stem tissue	5.20E-02	-7.10E-02	-2.72E-01
Non-alcoholic fatty liver disease	DB92	Liver tissue	9.81E-01	-7.98E-02	-4.42E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	1.44E-02	1.19E-01	2.06E+00
Olive pollen allergy	CA08.00	Peripheral blood	4.36E-01	1.11E-01	9.83E-01
Oral cancer	2B6E	Oral tissue	7.27E-04	-3.15E-01	-8.70E-01
Osteoarthritis	FA00-FA0Z	Synovial tissue	2.47E-01	-6.30E-02	-1.68E-01
Osteoporosis	FB83.1	Bone marrow	6.99E-01	3.16E-02	2.74E-01
Ovarian cancer	2C73	Ovarian tissue	1.50E-01	1.34E-01	6.46E-01
Pancreatic cancer	2C10	Pancreas	2.32E-03	-1.90E-01	-1.11E+00
Parkinson's disease	8A00.0	Substantia nigra tissue	1.04E-01	-3.45E-01	-1.05E+00
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	9.81E-01	-1.19E-02	-8.13E-02
Pituitary cancer	2D12	Pituitary tissue	7.34E-02	8.90E-02	4.56E-01
Pituitary gonadotrope tumour	2D12	Pituitary tissue	2.68E-01	7.22E-02	3.12E-01
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	8.34E-01	-1.95E-02	-5.44E-02
Polycythemia vera	2A20.4	Whole blood	7.20E-05	5.33E-02	3.69E-01
Pompe disease	5C51.3	Biceps muscle	2.32E-01	-4.10E-02	-2.74E-01
Preterm birth	KA21.4Z	Myometrium	6.21E-01	1.60E-02	1.06E-01
Prostate cancer	2C82	Prostate	1.45E-10	8.89E-01	2.45E+00
Psoriasis	EA90	Skin	8.65E-24	5.37E-01	1.54E+00
Rectal cancer	2B92	Rectal colon tissue	3.15E-02	-1.36E-01	-9.19E-01
Renal cancer	2C90-2C91	Kidney	3.01E-03	-5.65E-01	-1.54E+00
Retinoblastoma	2D02.2	Uvea	7.65E-04	-4.57E-01	-1.48E+00
Rheumatoid arthritis	FA20	Synovial tissue	2.96E-02	-3.36E-01	-9.12E-01
Rhinovirus infection	CA42.1	Nasal epithelium tissue	5.98E-01	3.43E-03	3.43E-02
Schizophrenia	6A20	Prefrontal cortex	8.03E-01	-4.19E-03	-1.64E-02
Schizophrenia	6A20	Superior temporal cortex	5.39E-01	8.87E-04	5.33E-03
Scleroderma	4A42.Z	Whole blood	5.08E-02	6.81E-02	5.33E-01
Seizure	8A60-8A6Z	Whole blood	7.73E-01	-2.76E-02	-1.32E-01
Sensitive skin	EK0Z	Skin	6.97E-01	7.94E-02	5.07E-01
Sepsis with septic shock	1G41	Whole blood	6.45E-02	3.21E-03	1.31E-02
Shwachman-Diamond syndrome	3A70.0	Bone marrow	1.01E-01	-9.82E-02	-5.20E-01
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	1.60E-01	2.74E-01	8.95E-01
Simpson golabi behmel syndrome	LD2C	Adipose tissue	2.01E-01	7.02E-02	3.71E+00
Sjogren's syndrome	4A43.2	Salivary gland tissue	2.94E-01	9.45E-02	2.79E-01
Skin cancer	2C30-2C3Z	Skin	2.64E-18	-5.78E-01	-1.36E+00
Thrombocythemia	3B63	Whole blood	5.00E-02	3.62E-02	2.93E-01
Thrombocytopenia	3B64	Whole blood	4.11E-01	1.41E-02	7.88E-02
Thyroid cancer	2D10	Thyroid	1.53E-05	5.25E-02	3.01E-01
Tibial muscular dystrophy	8C75	Muscle tissue	2.65E-04	-2.86E-01	-1.09E+00
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	8.38E-01	-1.57E-04	-6.45E-04
Type 2 diabetes	5A11	Liver tissue	1.33E-01	-2.80E-01	-1.21E+00
Ureter cancer	2C92	Urothelium	9.07E-01	9.96E-03	5.82E-02
Uterine cancer	2C78	Endometrium tissue	6.86E-11	3.09E-01	7.94E-01
Vitiligo	ED63.0	Skin	1.37E-01	2.11E-01	1.00E+00