Details of the Drug-Related molecule(s) Expression Atlas

General Information of DTP (ID: DTZAH46)

• DTP Name: Sodium/iodide cotransporter (SLC5A5) DTP Info
• Gene Name: NIS

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	2.96E-04	1.11E-01	3.23E-01
Adrenocortical carcinoma	2D11.Z	Kidney	1.96E-01	-4.48E-02	-1.39E-01
Alopecia	ED70	Skin from scalp	3.88E-01	-7.30E-02	-3.31E-01
Alzheimer's disease	8A20	Entorhinal cortex	6.41E-02	-2.55E-02	-1.04E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	7.36E-01	-4.45E-02	-5.38E-01
Aortic stenosis	BB70	Calcified aortic valve	7.16E-01	3.05E-02	4.28E-02
Apnea	7A40	Hyperplastic tonsil	3.61E-03	-4.94E-01	-2.16E+00
Arthropathy	FA00-FA5Z	Peripheral blood	6.30E-01	5.63E-02	3.89E-01
Asthma	CA23	Nasal and bronchial airway	6.79E-01	-1.97E-01	-3.24E-01
Atopic dermatitis	EA80	Skin	1.14E-02	9.74E-02	7.13E-01
Autism	6A02	Whole blood	2.13E-02	-1.77E-01	-6.07E-01
Autoimmune uveitis	9A96	Peripheral monocyte	4.14E-01	-7.43E-02	-4.40E-01
Autosomal dominant monocytopenia	4B04	Whole blood	3.64E-01	-3.81E-02	-2.32E-01
Bacterial infection of gingival	1C1H	Gingival tissue	9.55E-01	-4.27E-02	-1.32E-01
Batten disease	5C56.1	Whole blood	5.21E-01	1.42E-01	1.36E+00
Behcet's disease	4A62	Peripheral blood	6.88E-01	4.70E-02	1.87E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	5.11E-01	-3.92E-02	-2.14E-01
Bladder cancer	2C94	Bladder tissue	2.69E-05	7.06E-01	3.65E+00
Breast cancer	2C60-2C6Z	Breast tissue	7.70E-16	-2.18E-01	-5.48E-01
Cardioembolic stroke	8B11.20	Whole blood	2.30E-03	9.89E-02	5.92E-01
Cervical cancer	2C77	Cervical tissue	2.42E-01	-2.38E-02	-7.48E-02
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	1.14E-01	5.21E-02	1.89E-01
Chronic hepatitis C	1E51.1	Whole blood	3.07E-01	1.34E-01	5.54E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	2.01E-02	1.85E-01	7.22E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	4.16E-01	8.75E-02	2.89E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	5.21E-02	9.81E-02	1.33E+00
Colon cancer	2B90	Colon tissue	2.04E-15	-2.15E-01	-8.02E-01
Coronary artery disease	BA80-BA8Z	Peripheral blood	1.21E-01	4.50E-02	5.74E-01
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	7.45E-01	-1.78E-01	-5.56E-01
Endometriosis	GA10	Endometrium tissue	6.95E-01	3.16E-02	1.02E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	7.70E-01	-5.29E-02	-2.24E-01
Familial hypercholesterolemia	5C80.00	Whole blood	4.64E-03	-2.19E-01	-8.77E-01
Gastric cancer	2B72	Gastric tissue	2.31E-01	-8.08E-01	-1.53E+00
Glioblastopma	2A00.00	Nervous tissue	7.02E-08	-9.83E-02	-3.00E-01
Glioma	2A00.0Y-2A00.0Z	White matter tissue	1.52E-08	-9.51E-01	-4.69E+00
Head and neck cancer	2D42	Head and neck tissue	6.91E-06	1.26E-01	4.68E-01
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	2.63E-03	-1.30E-01	-6.48E-01
Huntington's disease	8A01.10	Whole blood	2.18E-01	7.81E-02	3.19E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	1.46E-01	3.08E-02	1.32E-01
Immunodeficiency	4A00-4A20	Peripheral blood	1.63E-01	4.81E-02	3.89E-01
Influenza	1.00E+30	Whole blood	2.17E-01	2.81E-01	1.54E+00
Interstitial cystitis	GC00.3	Bladder tissue	5.81E-01	9.83E-02	4.91E-01
Intracranial aneurysm	8B01.0	Intracranial artery	9.25E-01	1.14E-01	3.32E-01
Irritable bowel syndrome	DD91.0	Rectal colon tissue	6.64E-01	6.41E-02	1.64E-01
Ischemic stroke	8B11	Peripheral blood	2.80E-01	4.87E-02	2.56E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	8.79E-01	-2.59E-03	-1.17E-02
Lateral sclerosis	8B60.4	Cervical spinal cord	6.44E-01	-1.41E-01	-4.48E-01
Lateral sclerosis	8B60.4	Skin	2.85E-01	1.44E-01	1.09E+00
Liver cancer	2C12.0	Liver tissue	2.10E-04	-2.58E-01	-7.42E-01
Liver failure	DB99.7-DB99.8	Liver tissue	1.75E-01	1.05E-01	5.59E-01
Lung cancer	2C25	Lung tissue	4.91E-01	-1.43E-02	-4.82E-02
Lupus erythematosus	4A40	Whole blood	9.71E-03	-1.65E-01	-2.12E-01
Major depressive disorder	6A70-6A7Z	Whole blood	3.29E-01	4.97E-02	2.26E-01
Major depressive disorder	6A70-6A7Z	Hippocampus	7.17E-01	-1.06E-03	-5.56E-03
Melanoma	2C30	Skin	5.88E-01	1.48E-02	1.30E-02
Multiple myeloma	2A83.1	Bone marrow	4.95E-04	-3.46E-01	-2.18E+00
Multiple myeloma	2A83.1	Peripheral blood	6.09E-01	2.68E-02	2.13E-01
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	7.05E-01	6.03E-04	2.06E-03
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	2.52E-01	-8.94E-02	-3.56E-01
Myelofibrosis	2A20.2	Whole blood	8.79E-01	-4.82E-02	-3.09E-01
Myocardial infarction	BA41-BA50	Peripheral blood	8.02E-02	8.69E-01	1.01E+00
Myopathy	8C70.6	Muscle tissue	4.34E-02	-2.23E-01	-1.09E+00
Neonatal sepsis	KA60	Whole blood	7.11E-05	-1.27E-01	-3.91E-01
Neuroectodermal tumour	2A00.11	Brain stem tissue	1.33E-03	-4.87E-01	-1.68E+00
Non-alcoholic fatty liver disease	DB92	Liver tissue	7.81E-01	-6.00E-02	-3.01E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	3.51E-02	1.41E-01	1.46E+00
Olive pollen allergy	CA08.00	Peripheral blood	1.89E-01	3.30E-01	9.00E-01
Oral cancer	2B6E	Oral tissue	5.83E-05	-2.88E-01	-8.93E-01
Osteoarthritis	FA00-FA0Z	Synovial tissue	9.06E-01	3.28E-02	1.11E-01
Osteoporosis	FB83.1	Bone marrow	1.73E-04	6.64E-01	3.77E+00
Ovarian cancer	2C73	Ovarian tissue	3.15E-01	-2.45E-01	-6.71E-01
Pancreatic cancer	2C10	Pancreas	1.30E-01	-1.92E-01	-4.74E-01
Parkinson's disease	8A00.0	Substantia nigra tissue	2.58E-01	-1.22E-01	-4.90E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	9.28E-01	-6.22E-02	-3.52E-01
Pituitary cancer	2D12	Pituitary tissue	1.14E-01	4.74E-01	1.19E+00
Pituitary gonadotrope tumour	2D12	Pituitary tissue	6.70E-01	1.75E-03	4.91E-03
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	6.42E-01	1.02E-02	6.57E-02
Polycythemia vera	2A20.4	Whole blood	6.38E-01	-2.29E-02	-1.31E-01
Pompe disease	5C51.3	Biceps muscle	1.76E-01	-2.25E-01	-1.11E+00
Preterm birth	KA21.4Z	Myometrium	2.95E-01	-3.28E-03	-2.21E-02
Prostate cancer	2C82	Prostate	7.01E-04	-1.48E+00	-1.37E+00
Psoriasis	EA90	Skin	3.54E-11	-2.53E-01	-4.95E-01
Rectal cancer	2B92	Rectal colon tissue	1.36E-01	-2.78E-01	-8.17E-01
Renal cancer	2C90-2C91	Kidney	3.01E-02	-3.41E-01	-1.15E+00
Retinoblastoma	2D02.2	Uvea	4.17E-02	-1.95E-01	-1.29E+00
Rheumatoid arthritis	FA20	Synovial tissue	2.61E-01	-1.42E-01	-5.94E-01
Rhinovirus infection	CA42.1	Nasal epithelium tissue	6.58E-01	1.44E-02	8.85E-02
Schizophrenia	6A20	Prefrontal cortex	8.49E-01	4.69E-03	1.68E-02
Schizophrenia	6A20	Superior temporal cortex	9.87E-01	-1.23E-02	-8.36E-02
Scleroderma	4A42.Z	Whole blood	6.66E-04	3.34E-01	1.76E+00
Seizure	8A60-8A6Z	Whole blood	1.11E-01	-2.10E-01	-8.11E-01
Sensitive skin	EK0Z	Skin	5.85E-01	-7.48E-02	-3.95E-01
Sepsis with septic shock	1G41	Whole blood	1.82E-02	-2.04E-02	-6.11E-02
Shwachman-Diamond syndrome	3A70.0	Bone marrow	1.61E-01	3.69E-01	7.61E-01
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	4.41E-01	1.43E-01	4.61E-01
Simpson golabi behmel syndrome	LD2C	Adipose tissue	8.24E-01	-6.47E-02	-9.59E-01
Sjogren's syndrome	4A43.2	Salivary gland tissue	4.54E-01	-1.56E-01	-2.61E-01
Skin cancer	2C30-2C3Z	Skin	4.16E-10	-4.10E-01	-5.64E-01
Thrombocythemia	3B63	Whole blood	4.84E-01	5.16E-02	3.11E-01
Thrombocytopenia	3B64	Whole blood	4.54E-01	-8.07E-02	-2.83E-01
Thyroid cancer	2D10	Thyroid	4.49E-14	-4.45E-01	-7.18E-01
Tibial muscular dystrophy	8C75	Muscle tissue	3.32E-01	-1.10E-01	-4.83E-01
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	2.05E-01	4.77E-02	3.93E-01
Type 2 diabetes	5A11	Liver tissue	8.66E-01	-5.33E-15	-2.73E-14
Ureter cancer	2C92	Urothelium	7.50E-01	2.35E-02	1.34E-01
Uterine cancer	2C78	Endometrium tissue	5.43E-06	-2.43E-01	-8.42E-01
Vitiligo	ED63.0	Skin	7.54E-02	-1.05E-01	-5.92E-01