Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DME (ID: DE0JMZ5)

DME Name	Steroid 21-hydroxylase (CYP21A2) DME Info
Gene Name	CYP21A2

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Approved Drug(s)

Download the Complete Related Drug List

2 Approved Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Hydroxyprogesterone	DMIKQH5	Solid tumour/cancer	2A00-2F9Z	Approved	[1]
Progesterone	DMUY35B	Amenorrhea	GA20.0	Approved	[2]
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Molecule Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

References

1	Functional characterization of two novel point mutations in the CYP21 gene causing simple virilizing forms of congenital adrenal hyperplasia due to 21-hydroxylase deficiency. J Clin Endocrinol Metab. 2005 Jan;90(1):445-54.
2	Human cytochrome P450 21A2, the major steroid 21-hydroxylase: structure of the enzyme progesterone substrate complex and rate-limiting C-H bond cleavage. J Biol Chem. 2015 May 22;290(21):13128-43.