Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DME (ID: DE43MW5)

DME Name	Indoleamine 2,3-dioxygenase 1 (IDO1) DME Info
Gene Name	IDO1

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Approved Drug(s)

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2 Approved Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
L-Tryptophan	DMIBH7M	Depression	6A70-6A7Z	Approved	[1]
Melatonin	DMKWFBT	Depression	6A70-6A7Z	Approved	[2]
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Molecule Interaction Atlas

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References

1	Kynurenine pathway metabolites and enzymes involved in redox reactions. Neuropharmacology. 2017 Jan;112(Pt B):331-345.
2	Molecular evidence that melatonin is enzymatically oxidized in a different manner than tryptophan: investigations with both indoleamine 2,3-dioxygenase and myeloperoxidase. Biochem J. 2005 May 15;388(Pt 1):205-15.