Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DME (ID: DE6NIY9)

DME Name	Methionine synthase reductase (MTRR) DME Info
Gene Name	MTRR

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Approved Drug(s)

Investigative Drug(s)

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3 Approved Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Doxorubicin	DMVP5YE	Acute myelogenous leukaemia	2A41	Approved	[1]
Folic Acid	DMEMBJC	Colorectal carcinoma		Approved	[2]
Menadione	DMSJDTY	Vitamin K deficiency	5B59	Approved	[1]
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2 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Dichloroindophenol	DMAEI51	N. A.	N. A.	Investigative	[1]
Ferricyanide	DM1TH08	N. A.	N. A.	Investigative	[1]
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Molecule Interaction Atlas

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References

1	Differences in the efficiency of reductive activation of methionine synthase and exogenous electron acceptors between the common polymorphic variants of human methionine synthase reductase. Biochemistry. 2002 Nov 12;41(45):13378-85.
2	Polymorphisms in genes involved in folate metabolism as maternal risk factors for Down syndrome in China. J Zhejiang Univ Sci B. 2008 Feb;9(2):93-9.