Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DME (ID: DEASG0Q)

DME Name	Thymidylate synthase (TYMS) DME Info
Gene Name	TYMS

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Approved Drug(s)

Investigative Drug(s)

Download the Complete Related Drug List

2 Approved Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Fluorouracil	DMUM7HZ	Adenocarcinoma	2D40	Approved	[1]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[2]
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1 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
2'-deoxyuridylic acid	DMPV1LU	Discovery agent	N.A.	Investigative	[3]
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Molecule Interaction Atlas

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References

1	5-Fluorouracil pharmacogenomics: still rocking after all these years? Pharmacogenomics. 2011 Feb;12(2):251-65.
2	The pharmacogenetics of methotrexate. Rheumatology (Oxford). 2007 Oct;46(10):1520-4.
3	Distribution of mutations in human thymidylate synthase yielding resistance to 5-fluorodeoxyuridine. J Biol Chem. 2002 Sep 27;277(39):36304-11.