Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DME (ID: DEI8NGH)

DME Name	UDP-glucuronosyltransferase 2B10 (UGT2B10) DME Info
Gene Name	UGT2B10

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Approved Drug(s)

Download the Complete Related Drug List

4 Approved Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Cotinine	DMCEZ1B	Insecticide	N.A.	Approved	[1]
Desloratadine	DM56YN7	Allergic rhinitis	CA08.0	Approved	[2]
Ketotifen	DM74XKS	Allergic conjunctivitis	9A60.02	Approved	[]
Pizotyline	DMV74ZH	Headache	8A80-8A84	Approved	[3]
------------------------------------------------------------------------------------

Molecule Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

References

1	Human UDP-glucuronosyltransferase (UGT) 2B10: validation of cotinine as a selective probe substrate, inhibition by UGT enzyme-selective inhibitors and antidepressant and antipsychotic drugs, and structural determinants of enzyme inhibition. Drug Metab Dispos. 2016 Mar;44(3):378-88.
2	Further characterization of the metabolism of desloratadine and its cytochrome P450 and UDP-glucuronosyltransferase inhibition potential: identification of desloratadine as a relatively selective UGT2B10 inhibitor. Drug Metab Dispos. 2015 Sep;43(9):1294-302.
3	Human UDP-glucuronosyltransferase (UGT) 2B10 in drug N-glucuronidation: substrate screening and comparison with UGT1A3 and UGT1A4. Drug Metab Dispos. 2013 Jul;41(7):1389-97.